948 search results for “optimise drug design” in the Staff website
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In Memoriam - associate professor Hans Brussee
On 15 April, our much-beloved and highly respected former colleague Dr Hans Brussee passed away from cancer. In January 2025, Hans began experiencing neck pain. Initially, it appeared to be a herniated disc, but sadly, the diagnosis was soon revised, and his condition proved untreatable. Hans was 77…
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From liquid to solid: revolutionary technique uncovers disease-related changes in tiny droplets within our cells
Understanding the behaviour of tiny droplets in our cells could aid the search for new treatments. A team of Leiden researchers has developed a groundbreaking method to study how these droplets transition from liquid to solid. This change plays a role in various diseases, including neurodegenerative…
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NWO-XS grants for two innovative research projects
Two Leiden Science researchers received an NWO-XS grant for their research. Both projects are highly promising, but also high-risk. Macrophages that trap bacteria and data storage made from 2D materials convinced the board of their potential.
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European grants for research on ultrathin membranes and the biological clock in bacteria
Two research groups involving Leiden University have been awarded a major European grant, the ERC Synergy Grant. This for research on the development of membranes that can clean water and purify medical drugs and research on the biological clock in certain bacteria.
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Antibiotic resistance: an economic problem universities could help to solve
Antibiotic resistance is an economic problem. Pharmaceutical companies cannot earn much from antibiotic research, so they do not invest in it. This makes it important that universities do so, says Ned Buijs.
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‘A few nerves before lectures show that my work matters’
Giving an incorrect answer as a student in a packed lecture hall can be nerve-wracking. But with Pharmacology teacher Rob van Wijk, you don’t need to worry about that. ‘He creates a comfortable and safe atmosphere,’ his students say. They have nominated him for the Leiden Science Teacher Award.
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The career choices of cells
How does an embryonic stem cell decide if it becomes a heart cell or a kidney cell? That’s the question computational biologist Maria Mircea studied for her PhD research. She looked at the inside of individual cells to analyse how they change. This is what she discovered.
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In memoriam: Dr. Daniëlle A. Hamstra
On July 28, 2022, our dear colleague Daniëlle Hamstra passed away after a short sickbed. Daniëlle had been associated with the Clinical Psychology Section since 2010, initially as a student in the research master's program and subsequently as a lecturer and PhD candidate.
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Carlijn Lems wins the Suzanne Hovinga Award 2020-2021
During the LACDR Fall Symposium the Suzanne Hovinga Award for ‘best master thesis’ was awarded to Carlijn Lems for her master thesis entitled ‘Elucidating the crosstalk between epithelial-to-mesenchymal transition and Programmed Death-Ligand 1: validation and extension of a computational model’. Carlijn…
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Royal honour for emeritus professor Ad IJzerman
Ad IJzerman, Emeritus Professor of Pharmacochemistry, was made a Knight of the Order of the Lion of the Netherlands on 26 April. He was presented with the royal honour by Mayor Elbert Roest in the town hall in Bloemendaal.
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Remarkable PhD research: diagnosing sepsis in premature babies
How can we diagnose the life-threatening condition sepsis in premature babies as quickly and accurately as possible? That is what PhD student Manchu Thangavelu from the Leiden Academic Centre for Drug Research (LACDR) wants to figure out.
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Review on “Anticancer opportunities at every stage of chemokine function” is featured on the cover of TIPS
Last November, Dr. Natalia Ortiz, Martijn Bemelmans (MSc), and Prof. Laura Heitman published a review in Trends in Pharmacological Sciences (TIPS) on targeting the chemokine system in cancer (https://doi.org/10.1016/j.tips.2021.08.001). The review was written in collaboration with Prof. Tracy Handel…
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AMPK activation as host-directed therapy to improve tuberculosis treatment: Computational characterization and prediction of intracellular pharmacology
Rob van Wijk (LACDR, Leiden University) and Robin van den Biggelaar (LUCID, LUMC) have been awarded a €10,000 euro KIEM grant from Leiden University to start an interdisciplinary collaboration to investigate the potential of AMPK activation as an adjunctive therapy to enhance tuberculosis treatment.
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Will you be our new Research Theme Leader?
Research
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Looking at toxicodynamic variation in the human population to address chemical safety
The European Food Safety Authority (EFSA) has awarded a €1.6M contract to an LACDR-led consortium to assess how sensitivity to toxicity caused by chemicals varies among individual people. Currently these toxicodynamic differences are an unknown source of uncertainty when carrying out risk assessment…
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Vincent Delhomme successfully defends his PhD on the regulation of lifestyle risks in EU law
On Friday 2 June 2023, Vincent Delhomme, Assistant professor at the Europe Institute at Leiden Law School, successfully defended his PhD thesis entitled : ‘Regulating lifestyle risks in EU law: Promoting health in a diverse market’.
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In memoriam Hans Junginger
On 25 May 2024, our much-loved former colleague prof.dr.dr.h.c.mult Hans E. Junginger passed away.
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Natalia Ortiz – Winner of the 2019 - 2020 KNCV Medicinal Chemistry & Chemical Biology thesis prize
Natalia Ortiz (Division of Drug Discovery and Safety) has been awarded the 2019-2020 PhD-thesis prize by the Division of Medicinal Chemistry & Chemical Biology, from the Royal Netherlands Chemical Society (KNCV-MCCB). The KNCV-MCCB thesis prize is a biannual award which is granted to the best PhD thesis…
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These eleven Leiden Science researchers are among the most highly cited
Eleven researchers of the Faculty of Science are on the 2021 Highly Cited Researchers list of Clarivate Analytics. Only 0.1 per cent of researchers are included in this list, literally making them one in a thousand.
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Bart Custers comments on Telegram’s catalogue of crimes
Instant messaging app Telegram is not faring well in the news – the reason being the illicit activities occurring on the platform. Professor Bart Custers helped Dutch current affairs programme ‘EenVandaag’ respond to questions about the platform.
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Maaike van der Lee wins the national PhD competition 2021 at the FIGON Dutch Medicine Days
We are congratulating Maaike van der Lee, PhD candidate at LUMC-KFT, for winning the national PhD competition 2021 at the FIGON Dutch Medicine Days. During this national competition, 8 researchers from the major university cities in the Netherlands present their work in the field of innovative medicine…
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Thirteen NWO Open Competition XS grants for Leiden researchers
From medicines from snake venom to supercrops and the origin of words. Thirteen researchers from Leiden University will receive Open Competition XS grants from the Dutch Research Council (NWO).
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Sustainability and energy: AI research in Leiden, Delft and Rotterdam
From energy transition to the nitrogen crisis: artificial intelligence can be of great help. Researchers from the three universities in Zuid-Holland are seizing the opportunity. Three of them talk about collaborative research in the AI for Energy and Sustainability focus group within the Zuid-Holland…
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Mitra BaratchiFaculty of Science
m.baratchi@liacs.leidenuniv.nl | 071 5277492
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Veni grants for 18 Leiden researchers
Eighteen researchers from Leiden University have been awarded a Veni grant by the Dutch Research Council (NWO). This grant gives promising young researchers the opportunity to develop their ideas for a period of three years.
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Tingjie GuoFaculty of Science
t.guo@lacdr.leidenuniv.nl | 071 5274501
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Catherine MergenFaculty of Science
c.mergen@lacdr.leidenuniv.nl | 071 5276038
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Frits RosendaalFaculty of Medicine
f.r.rosendaal@lumc.nl | 071 5264037
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Adam CohenFaculty of Medicine
ac@chdr.nl | 071 5269111
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Laura ZwepFaculty of Science
l.b.zwep@lacdr.leidenuniv.nl | 071 5272727
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Ferry OssendorpFaculty of Medicine
f.a.ossendorp@lumc.nl | 071 5263800
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Catherijne KnibbeFaculty of Science
c.knibbe@antoniusziekenhuis.nl | 071 5276329
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Marcel TijstermanFaculty of Medicine
m.tijsterman@lumc.nl | 071 5269111
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Marcellus UbbinkFaculty of Science
m.ubbink@chem.leidenuniv.nl | 071 5274628
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Bram SlütterFaculty of Science
b.a.slutter@lacdr.leidenuniv.nl | 071 5276208
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The Erasmus+ grant opens doors
What is it like to participate in the Erasmus+ grant programme as a Master's student from Ukraine? Yevhenii Radchenko did an eight-month internship at Leiden University in 2018. Soon after, he returned as a PhD candidate. 'You have little to lose, but a lot to gain.'
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Maureen Rutten - van Mölken: 'Investeren in innovaties die de meeste gezondheidswinst opleveren'
Digitale medische technologie kan een belangrijke bijdrage leveren aan betaalbare zorg en het oplossen van het tekort aan zorgpersoneel. Maar hoe weet je of een innovatie daadwerkelijk waarde toevoegt aan het zorgsysteem?
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Rawi Ramautar new Programme Director of Bio-Pharmaceutical Sciences bachelor’s program
Rawi Ramautar will be the new Programme Director of the bachelor of Bio-Pharmaceutical Sciences starting September 1. The appointment is for four years. Ramautar succeeds Erik Danen, who has held the position since 2019.
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Carsten Stahn: 'New ICC prosecutor can bring new momentum'
On Wednesday 16 June 2021, Karim Khan was sworn in at the International Criminal Court (ICC) in The Hague. Experts say this is no easy time to join the ICC.
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LACDR-Bruker Bio-AFM workshop: connecting disciplines through force spectroscopy
On the 6th and 7th of September 2023, the Leiden Academic Centre for Drug Research (LACDR) organized the Leiden Bio-AFM workshop in cooperation with Bruker Nano GmbH (Germany) and Bruker Nederland BV. The organization of this event was led by the Medical Systems Biophysics and Bioengineering group (Alireza…
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Bold and anxious fish help in the hunt for medication for ADHD and depression
Personality is genetic in zebrafish: risk-taking parents have risk-taking children. These are the findings of research by Christian Tudorache and his team published in BMC Neuroscience.
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Pauline Schuyt: 'Life imprisonment demand ineffective if goal is deterrence'
The number of life sentences in the Netherlands is rising sharply. This is a clear response to the serious drugs violence and brutal attacks on our rule of law. However, criminal justice experts do not believe that this will deter future offenders from carrying out liquidations.
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Suzanne van der Pluijm to be Science Faculty’s new Executive Director
Suzanne van der Pluijm will be appointed Executive Director and Member of the Board of the Faculty of Science with effect from 1 June 2022. She succeeds Ed van den Berg, who has held this position on an interim basis since 1 September 2021 .
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LACDR Spring symposium 2025
It was great to welcome so many people at the LACDR Spring symposium which was held on May 19th. After an inspiring lecture of Dr. Frederica Eduati, associate professor at the Eindhoven University of Technology, the PhD speakers impressed with their talks. The poster sessions gave a good inside in the…
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Miranda van Eck new Scientific Director of the LACDR institute
As of 1 September Miranda van Eck will be the new Scientific Director of the Leiden Academic Centre for Drug Research. She succeeds Hubertus Irth, who led the institute since 2016. Van Eck has been appointed for a period of four years.
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Templeton Grant Drukker News
In a project funded by the John Templeton Foundation to the group of Micha Drukker, scientists will produce stem cells from short and long living understudied species to model cellular and organismal lifespan.
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More attention needs to be paid to prevention in the fight against cancer
On 11 November Professor of Gastroenterology and Hepatology, Monique van Leerdam will deliver her inaugural lecture entitled, ‘Aiming for Prevention’. Van Leerdam, who specialises in hereditary tumours, was appointed professor in July 2020. In her inaugural lecture she will discuss the importance of…
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Faculty Council FSW: an update on participation
The academic year 2021-2022 is already past the halfway mark. That also means that the current members of the Faculty Council have been at work for more than half a year. Time for an update with staff members Evelien Wolthuis and Kiki Zanolie.
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ICT conference Our Digital Future: ‘This touches on everything we do here’
What are the digital challenges facing us now and in the near future? This was the question discussed by over 250 ICT experts, functional application management staff and information managers during the Our Digital Future conference on 26 January. We asked some of them how they found the day and what…
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Dutch Research Council pilot programme funding for seven researchers
Seven researchers from Leiden University have made a successful application to the Open Competition SSH (Social Sciences and Humanities) XS, a Dutch Research Council pilot programme.