1,129 search results for “optimize drug design” in the Staff website
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Aleida Nijland on Track: Preliminary Design Approved
With the approval of the preliminary design (PD), an important milestone has been reached in the design process for the Aleida Nijland building. This means that the key functional and spatial decisions have now been finalised. The future users of the building – LUCL, part of LUCAS, lab users, LAK, ATC,…
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Art Academy students design 450th anniversary logo
Students from the Royal Academy of Art The Hague (KABK) designed the 450 lustrum logo.
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Laura HeitmanFaculty of Science
l.h.heitman@lacdr.leidenuniv.nl | 071 5274558
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Man-made antibodies may change the future of drug development – here’s why
Sometimes an idea seems so logical and elegant at first glance, that you later wonder why no one thought of it before. Two researchers from LACDR have teamed up to develop a completely synthetic alternative to antibodies—one that mimics their size, shape and function, but which is cheaper, more stable,…
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Drugs for our immune system in the right place at the right time
Immunologist Leender Trouw specialises in the complement system, which is part of the immune system. In some diseases drugs help activate or inhibit this system. This is best done ‘in the right place at the right time’ − the title of his inaugural lecture.
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Thomas BäckFaculty of Science
t.h.w.baeck@liacs.leidenuniv.nl | 071 5277108
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Opening of Academic Year on sustainability: optimism and criticism go hand in hand
The theme of the Opening of the Academy Year on 4 September was sustainability and how the university could take the lead as a change agent. How is it going about this and what else can it do? There was also room for a critical note.
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der Hof joins Special Group on Code of Conduct for age-appropriate design
Simone van der Hof, professor of Law and Digital Technology at eLaw, has joined the EU Special Group on Code of Conduct for age-appropriate design as an expert.
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From lab discovery to a new drug: the Venture Challenge makes it possible
A breakthrough from the PhD research of medical chemist Elmer Maurits may help patients with autoimmune diseases and blood cancer in the future. But bringing a discovery from the lab to the clinic is not so easily done. Thanks to NWO's Venture Challenge, Maurits and his team will receive ten weeks of…
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Creative Call: Help us name and design the logo for our Humanities Labs!
Organisation
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Jurian LockFaculteit der Rechtsgeleerdheid
j.i.w.lock@law.leidenuniv.nl | 071 5272727
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Todor StefanovFaculty of Science
t.p.stefanov@liacs.leidenuniv.nl | 071 5275776
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Eline DekeysterFaculty of Social and Behavioural Sciences
e.a.g.dekeyster@fsw.leidenuniv.nl | 071 5272727
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Bas GouloozeFaculty of Science
s.c.goulooze@lacdr.leidenuniv.nl | 071 5276329
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Efficient Constraint Multi-Objective Optimization with Applications in Ship Design
PhD defence
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Grant Elise Mathilde Fund & LUF: Using virus to kill bacteria: design of innovative phage-antibiotic combination treatments to combat antimicrobial
Phage therapy is a novel yet unmatured therapeutic approach in the face of the crisis of antimicrobial resistance (AMR). Dr. Tingjie Guo received a grant from the Elise Mathilde Fund and the LUF to develop innovative phage-antibiotic combination treatment strategy for combating AMR.
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Skin researcher calls for multidisciplinary collaboration: ‘I want to pool expertise’
In dermatology, there should be a high level of multidisciplinary collaboration among institutes and specialists, Professor of Translational Dermatology, Robert Rissmann, will say in his inaugural lecture on 8 July. He is building an infrastructure that will put pre-clinical and clinical skin research…
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Publication on the design of multifunctionalized nanoparticles
Despite considerable progress in the design of multifunctionalized nanoparticles (NPs) that selectively target specific cell types, their systemic application often results in unwanted liver accumulation. The exact mechanisms for this general observation are still unclear.
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European Proof of Concept grants for two Leiden researchers
Two Leiden researchers have been awarded ERC Proof of Concept grants. These grants, each worth EUR 150,000, will help the grantees in their efforts to bridge the gap from basic science to real-life applications
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Centre for Innovation launches podcast about Design Thinking
How do you put students at the centre of education? And how do you make your research action-oriented? A new podcast by the Centre for Innovation answers these question. In Design Thinking in Education, four lecturers and two students talk about educational innovation.
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Design METIS instrument for the Extremely Large Telescope finalised
The design for the METIS instrument for the Extremely Large Telescope (ELT) is final. The European Southern Observatory (ESO) has given the green light for production of all parts of the instrument. It is the first ELT instrument, designed and to be built under Dutch leadership, to formally pass the…
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Meiling GaoFaculty of Science
m.gao@biology.leidenuniv.nl | 071 5276592
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Madeline KavanaghFaculty of Science
m.e.kavanagh@lic.leidenuniv.nl | 071 5272727
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Design plan for Aleida Nijland building presented during user meeting
Future users of the Aleida Nijland building were recently the first to have the opportunity to admire the design plan for the new building. During a user meeting, architectural firm De Zwarte Hond presented the design, and future users of the building were able to share their wishes and ideas for further…
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Accounting for diversity in robot design, testbeds, and safety standardisation
Eduard Fosch-Villaronga from eLaw - Center for Law and Digital Technologies, and Hadassah Drukarch, explored the role of intersectionality within (rehabilitation) robot design, testbed, and standards. Being oblivious to these considerations may give way to the development of robots that fall short of…
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The Humanities Campus development continues: North Cluster design process begins
Now that the South Cluster is reaching its concluding phase, we are looking ahead to the next building to be developed in the context of the Humanities Campus: Matthias de Vrieshof (working title: North Cluster).
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Lina van DrunenFaculty of Social and Behavioural Sciences
l.van.drunen@fsw.leidenuniv.nl | 071 5272727
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Dirk VisserFaculteit der Rechtsgeleerdheid
d.j.g.visser@law.leidenuniv.nl | 071 5277888
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A future with tailored therapy for patients with atherosclerosis
The AtheroNeth consortium received €6 million from the Dutch Heart Foundation to gain a better understanding of the differences in disease progression among patients with atherosclerosis. The ultimate goal is to enable personalised treatment.
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Marije NiemeijerFaculty of Science
m.c.niemeijer@lacdr.leidenuniv.nl | 071 5276105
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Bas ter BraakFaculty of Science
s.j.ter.braak@lacdr.leidenuniv.nl | 071 5272727
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and Italian pharma company receive an EU grant to realise sustainable drug production
With a €1.5 million European grant, industrial ecologist Stefano Cucurachi will work on more sustainable production methods for the pharmaceutical industry. The Italian company Angelini Pharma intends to use the resulting knowledge to make its production process more sustainable.
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LACDR introduces ‘Digital Labcoat’ for Biopharmaceutical Sciences students
Learn to program, gain knowledge of AI methods, or use it in a research project at the LACDR. With the introduction of the innovative digital learning environment ‘Digital Labcoat’, Biopharmaceutical Sciences bachelor students can further develop their computational skills.
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Skip ThijssenFaculty of Science
s.thijssen@liacs.leidenuniv.nl | 071 5272727
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More control over your future with designing your future
The future does not yet exist, but many people think about it daily. The course Designing Your Future, part of the Honours Programme at the Faculty of Governance and Global Affairs and taught by Bram Hoonhout‘Being a mentor during HOP week is something I can recommend to everyone’
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BPS MSc course Design, Analysis, and Practical Use of Biologicals
BPS MSc student Guus Ruiter: This year I followed this new course called Design, Analysis, and Practical Use of Biologicals at the LUMC given by Rawi Ramautar and developed for both BPS MSc and Pharmacy students. During this course, there were many different speakers, in particular from biotech companies…
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During the next pandemic, this mathematical model will speed up the search for treatment
Do you recall all those drugs that were hastily proposed as potential treatments for COVID-19? In the event of a future pandemic, the goal is to offer an effective treatment more quickly and efficiently. To achieve this, a team led by Coen van Hasselt is developing a platform that can speed up the process…
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A faster way to find new medicines – without the limitations of big DNA barcodes
Leiden researchers, led by Sebastian Pomplun developed a new method to screen hundreds of thousands of molecules for drug discovery, using mass spectrometry instead of DNA tags. ‘We wanted to make drug discovery faster and more accessible.’
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How Oncode-PACT is bringing new cancer medicines closer with 325 million in Growth Fund money
How can you ensure that more experimental drugs reach the finish line? At the moment, only one in twenty cancer drugs that are tested on humans makes it to the market. This is an enormous loss for patients and society. With a grant from the National Growth Fund, Oncode-PACT aims to efficiently select…
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The Nobel Prize in Chemistry went to an AI model (and rightly so)
Not experiments and lab coats, but computers and artificial intelligence: this year's Nobel Prize in Chemistry went to the inventors of the groundbreaking AI model, AlphaFold. This programme accurately predicts protein structures based on their genetic code—a crucial step in understanding biological…
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Mario van der SteltFaculty of Science
m.van.der.stelt@chem.leidenuniv.nl | 071 5274768
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Optimizing antifungal treatment through pharmacometrics: dosing considerations for enhanced efficacy
PhD defence
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UMCs join forces to increase pandemic preparedness
Four university medical centres, including the LUMC, are joining forces to increase pandemic preparedness in the Netherlands.
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Margo DonaFaculty of Science
m.a.dona@biology.leidenuniv.nl | 071 5272727
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Dan XuFaculty of Science
d.xu@liacs.leidenuniv.nl | 071 5277061
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Randal SheppardFaculty of Humanities
r.c.sheppard@hum.leidenuniv.nl | 071 5272656
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Laura de JongFaculty of Science
l.m.de.jong@lacdr.leidenuniv.nl | 071 5272727
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From discovery to business: 'In the lab, we often don't realise that we are working to help an immense number of patients'
'It gave our team a big boost to hear that our work was valuable,' says medical chemist Elmer Maurits about the moment they won the Venture Challenge. With their company Iprotics, they want to develop a drug that can better treat patients with autoimmune diseases and blood cancers. 25,000 euros of prize…
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Corrugated plastic unveils a new design principle for programmable materials
Martin van Hecke en Anne Meeussen publiceren in het tijdschrift Nature over mechanische metamaterialen. Ze hebben een nieuwe klasse multistabiele materialen ontdekt. Dit is gebaseerd op ribbeltjes plastic.
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RARE-NL: LUMC joins consortium to find treatments for rare diseases
RARE-NL, a new collaboration between university hospitals, hopes to find treatments for rare diseases. Professor Teun van Gelder is representing the LUMC in the initiative.