Despite being the second largest transmembrane protein family after GPCRs, the SLC superfamily has only gained significant attention in early drug development over the past decade.

We report new computational and experimental evidence of an efficient and astrochemically relevant formation route to formaldehyde (H2CO). This simplest carbonylic compound is central to the formation of complex organics in cold interstellar clouds and is generally regarded to be formed by the hydrogenation…

Pericytes, the mural cells of blood microvessels, are important regulators of vascular morphogenesis and function that have been postulated to mechanically control microvascular diameter through as yet unknown mechanisms.

In this thesis new methodologies are developed for the detection and systematic study of radio sources in the early universe. This allows us to gain a deeper understanding of the formation and evolution of galaxies, the activity of supermassive black holes, and the final phase transition of our universe:…

This book offers a new direction for the study of contemporary Islam by focusing on what being Muslim means in people’s everyday lives.

What are the university's requirements for PhD candidates? How do you organise your PhD track? You read all about it in the regulations, guidelines and golden rules.

Automated Machine Learning (AutoML) is widely used to automatically build a suitable practical Machine Learning (ML) model for an arbitrary real-world problem, reducing the effort of practitioners in the ML development cycle for real-world applications. Optimization is a key part of a typical AutoML…

Promotor: Prof.dr. A.G.G.M. Tielens, Prof.dr. C. Dominik (UvA)

In this paper, the authors outline how the UK and USA adopt the Chilean pension model without proper attribution, potentially distorting the lessons.

Promotor: Prof.dr. H.V.J. Linnartz, Co-Promotores: H.M. Cuppen, S. Ioppolo

Quantum computing is an emerging technology, which holds the potential to simulate complex quantum systems beyond the reach of classical numerical methods.Despite recent formidable advancements in quantum hardware, constructing a quantum computer capable of performing useful calculations remains challenging.In…

In this article, Ben S. Kuipers and Joanne Murphy review recent critiques of leadership theory and practice.

Promotor: M. Ubbink, Co-promotor: G. Siegal

The programme group Forensic Family and Youth Care Studies is one of the six programme groups within the department of Child and Education Studies at Leiden University.

Leiden University Centre for Linguistics (LUCL) is a reputable institute in the field of linguistics, offering excellent research and education opportunities covering a broad range of languages of the world.

Promotor: J.N. Kok, Co-promotor: H.J. Hoogeboom

Since 1990 Leiden University has awarded the William of Orange medal to individuals of eminent national or international social standing.

Human vocal communication and music perception represent advanced cognitive skills, seemingly innate and universal. These faculties encompass a range of perceptual and cognitive abilities. Cross-species research sheds light on the origins of musicality by investigating whether these traits are shared…

We investigate how radiation pressure can be used to influence the mechanical motion of a micro-mirror suspended from springs.

This thesis introduces the concept of

The research described in this thesis combines the latest insights in lysosomal function with lysosome centred cell signalling.

Methods for accurately computing the interaction of molecules with metal surfaces are critical to understanding and thereby improving heterogeneous catalysis.

Former clients en projects

This inaugural lecture discusses the question: How to cooperate in the digital era?

This dissertation aims to advance understanding of amoeboid single cell migration under the influence of changing physicochemical environmental properties. The particular focus is on the relatively unknown influence of differing physical properties in the extracellular environment, such as the migratory…

Promotor: F. Arbab, R. De Nicola, Co-Promotor: M. Tribastone

The Faculty of Governance and Global Affairs is situated at three locations in The Hague's city centre.

The Governance of Crises research group at Leiden University focuses on both research and education. They offer students in-depth knowledge of crisis management, with an emphasis on prevention, response, and recovery.

Almost all bacteria are enveloped by a cell wall that provides cellular protection.

Gorlaeus Building, Einsteinweg 55, 2333 CC, Leiden

Every day, we make numerous decisions, from choosing what to eat to how we interpret the world around us. Traditionally, researchers have assumed that a key part of our decision-making process, namely the decision criterion, stays stable over time. However, increasing evidence suggests that instead…

Promotor: Prof.dr. J.N. Kok

Public leadership received increasing attention, but we still do not understand how the context of public leaders affects leadership. This research project delves into public leaders’ perceptions of the leadership situations they find themselves in, which are characterised by multiplicity – one could…

Bacteria are highly complex and diverse organisms that have adapted to survive in ecological niches ranging from the most extreme to the most heterogeneous environments.

The University buildings in The Hague are all in the city centre, within walking distance of the stations.

The Centre for Professional Learning (CPL) develops in-depth and challenging programmes for higher educated professionals.

Molecular complexes can be used as electrocatalysts for oxygen reduction, water oxidation, and/or hydrogen peroxide production.

The importance of diversity and inclusion within society and its institutions can never be understated. In an interdependent, globalised world, we are more connected than ever, but we also face the risks of being more polarized than ever due to misunderstanding and misinformation. It is, therefore,…

Active-site directed probes are powerful in studies of enzymatic function. We report an active-site directed probe based on a warhead so far considered unreactive.

Detecting nanoscopic objects plays an important role in nanoscience in particular, in the rapidly growing field of nanobiology. The forebear to modern super-resolution microscopy for single molecule investigation, is fluorescence microscopy.

The research of our group is centered around dynamical systems, functional analysis and their interplay.

With an emphasis on developing novel miktoarm star polymers termed PeptoMiktoStars, this thesis leverages asymmetric polymeric polypept(o)ide frameworks to advance their effectiveness in delivering hydrophobic drugs and nucleic acids.

Discovery of metastasis promoting candidate drug targets

Promotores: Prof.dr. M. Franx & Prof.dr. P.G. van Dokkum (Yale University)

Van Steenis, Einsteinweg 2, 2333 CC, Leiden

Every year, the Leiden Institute of Physics (LION) organises the Science Day. The goal is to highlight the newest research at LION, to socialise, and to welcome first year master students and new PhD's and Postdocs to our institute.

The debate about Africa’s changing relations with the world has rapidly evolved over the past decade. The initial emphasis on China’s role in Africa has given way to a more diversified approach, acknowledging that other emerging global players have also become important.

The Laboratory for Archaeozoological Studies is an advanced laboratory with advanced Leica stereomicroscopes and measuring instruments and an extensive reference collection which is used for research e.g. the identification of fossil remains. The collection is also used for teaching students the anatomy…

Promotor: Erik F. Smets, Co-promotores: Barbara Gravendeel, Niels Raes

Promotores: Prof.dr. C.U. Keller, Prof.dr. H.C. Gerritsen