Promotor: A. Kros

Human and animal cells are very complex: very different chemical processes are going on at the same time, but they are separated from each other because the cells are divided in compartments. These compartments may also have a profound effect on the potential efficacy of therapeutics, because the drug…

This volume provides an authoritative, cutting-edge resource on the characteristics of both technological and social change in warfare in the twenty-first century, and the challenges such change presents to international law.

Saeedeh Shahnahpur defended her thesis on 13 September 2016.

Study information

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Salvador Santino Regilme has been selected for a fellowship at the Netherlands Institute for Advanced Study (NIAS) in Amsterdam. From September 2022, he will spend 5 months at NIAS working on his research project titled 'The Normative Order of the Global War on Drugs'.

Why does the past elicit this intense activity in the present? What does the past mean for the present, and what does it do to it? A WAR OF WORDS will engage this complex of Chinese claims to Manchu-Korean ancient history, South Korean reactions, public discourse and cultural expression in both states,…

Activity-based protein profiling (ABPP, also termed chemical proteomics), is one of the pillars of chemical biology, and at LED3 we have taken it to the next level. ABPP allows the assessment of protein function in live cells and tissues, which means that the activity of a complete protein family can…

Promotor: A.P. IJzerman Co-promotor: L.H. Heitman

Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.

Are you thinking about studying Crisis and Security Management: War and Peace Studies? Learn more and watch the videos.

Promotores: Prof.dr. H. S. Overkleeft, Prof.dr. G. A. van der Marel

If Dutch cinema is examined in academic studies, the focus is usually on pre-war films or on documentaries, but the post-war fiction film has been sporadically addressed.

Analysis of drug adversity

In this article, Marieke Liem and Kim Moeller revisit Goldstein’s framework on the drugs-violence nexus

Archaeologist Bjørn Peare Barthold suspected farmers in a doctorless 19th century Dutch village may have been self-medicating to manage pain and disease. By examining the skeletons' dental calculus this hypothesis could be tested. Science Magazine interviewed him about this new technique.

Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: Dr. L.H. Heitman

High throughput microscopy

Through a range of case studies spanning the post-Cold War period in Iraq, Moldova and Serbia, this book studies asymmetric conflicts where warring sides exhibit vast power differentials.

This project’s aim is to critically assess current homicide data sources in order to develop a proposal for long-term EU-level monitoring of DRH.

Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.

The Revolt in The Netherlands erupted in 1566 and tore apart the Low Countries. In Memory Wars in the Low Countries, 1566-1700 Jasper van der Steen explains how public memories of the Revolt in the Habsburg Netherlands in the South and the Dutch Republic in the North diverged and became the objects…

This book offers novel perspectives on the national and international dimensions of the post-war welfare state in Western Europe and North America.

Source: Nature Biotechnology, Volume 2014, Issue June (2014)

In neonates and infants, body size, enzyme pathways, and expression and function of receptors and (target) proteins are still developing.

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Promotores: C.A.J. Knibbe; J.N. van den Anker, Co-promotores: H.P.A. van Dongen; B. van Ramshorst

From descriptive to physiological models that can predict oral absorption and elimination of CYP3A substrates across the pediatric age range.

Promotor: A.P.IJzerman Co-promotor: A. Bender

Tom Buitelaar is an Assistant Professor in the War, Peace & Justice programme of the Institute of Security and Global Affairs. This paper discusses four important challenges to the involvement of UN peace operations in international criminal justice: its effects on host state relations, peace and justice…

In this article, Ben de Jong, research fellow at the Institute of Security and Global Affairs, examines the relationship between double agents and their handlers.

Promotor: B. van de Water

He’s a fast and animated speaker, which is only logical because Gerard van Westen is driving an express train. His destination? A virtual human, consisting of algorithms that predict what an administered substance will do in the body. The train is already a long way down the line and the pharmaceutical…

The historiography of the Bretton Woods conference of July 1944 is dominated by the personal clash between the principal negotiators, Harry Dexter White of the United States and John Maynard Keynes of Britain.

The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.

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Growth hormone profiles are pulsatile and highly variable between individuals, limiting the implementation of mathemathical models to quantify an individual's secretion.

In the last two decades, there have been heated public and scholarly debates in France, the United Kingdom, and the Netherlands on the violent end of empire. Nevertheless, the broader comparative investigations into colonial counterinsurgency tend to leave atrocities such as torture, execution, and…

Political scientist Corinna Jentzsch (Leiden University) about the organisation of rebel and government auxiliaries in the civil war in Mozambique (1976–1992).

The Afro-Asianism of the early Cold War has long remained buried under the narrative of Bandung, homogenising and subverting the different visions of post-colonial worldmaking that co-existed alongside the Bandung project.

Supervisor: Lizi Xia

The path to rational drug and dose selection

Exploring the mechanism of targeted nanoparticle-mediated drug delivery using the zebrafish model

Onderzoek van de onderzoeksgroep 'War, Peace and Justice'

The polypept(o)ide hybrid material attracted more and more attention over the past decade by combining the multifunctional characteristics of polypeptides with the shielding characteristics of polypeptoid-pSar possessing similar properties as a shielding material as polvethylene glycol(PEG). Polysarcosine…

Japan's Occupation of Java in the Second World War draws upon written and oral Japanese, Indonesian, Dutch and English-language sources to narrate the Japanese occupation of Java as a transnational intersection between two complex Asian societies, placing this narrative in a larger wartime context of…

Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)

Drug induced organ toxicity is the main problem of the drug development and drug usage in the clinic. The liver and kidneys are the most sensitive organs towards drug induced toxicity.

Source: Biosens Bioelectron, Volume 74, pp. 233-42 (2015)