Accelerating the development of new cancer medicines by joining forces—that’s the mission of Oncode Accelerator, a Dutch consortium that recently welcomed three Leiden-based PhD candidates. Under the guidance of Gerard van Westen, Marc Boef, Remco van den Broek, and Lucina-May Nollen are exploring how…

Aad van der Vaart, professor of stochastics at Leiden University, has been awarded the NWO Spinoza Prize for his groundbreaking research in statistics. Van der Vaart conducts fundamental research on models that can help, for instance, to identify genes that play a role in cancer.

Gilles van Wezel will step down as Scientific Director (SD) of the Institute of Biology Leiden (IBL) as of June 17th. He has held this position since September 2018. Van Wezel will be temporarily succeeded by Hubertus Irth, the current SD of the Leiden Academic Centre for Drug Research (LACDR). Irth…

When the tokay gecko loses its tail, a new one grows from resident stem cells at the stump. Each tissue type - muscle, bone, blood vessels and skin - develops from specific stem cells. This discovery by Luthfi Nurhidayat holds potential implications for advancing regenerative medicine in humans. Nurhidayat…

An international team of researchers, including Federico Calle-Vallejo of Leiden University’s Institute of Chemistry, have taken the atomic-scale design of catalysts to the next level. Their research contributes to the quest for a method to generate or store energy more efficiently. The report is published…

Sjaak Neefjes, Professor of Chemical Immunology at Leiden University, will receive the NWO Spinoza Prize this year. The Spinoza Committee called Neefjes an ‘exceptional researcher whose intelligence is matched by his boldness’. He will use the 2.5 million euro prize to pursue his research into cancer…

For medical research, researchers often recreate tissue in the lab. Organ-on-a-chip technology emulates organs, right down to the blood that flows through them, thus creating a realistic test model for drugs or research into disease processes. Researchers from the LUMC are coordinating an NWO Gravitation…

Five of the new Medical Delta professors who now hold an appointment at multiple institutions are affiliated with Leiden University/LUMC. They are psychologist Andrea Evers and four LUMC professors.

What dose of medicine do you give a child? That depends to a large extent on how quickly their kidneys remove the drug from the blood. For ethical reasons it is impossible to measure this directly in little patients. PhD candidate Sinziana Cristea combined different types of modelling and lots of data…

From artificial intelligence to letters from the Dutch East Indies and from breast-cancer gene BRCA-1 to the collaboration between government and opposition: nine researchers from Leiden University have been awarded a Vidi grant for their research.

One used 3D cell models to study colorectal cancer, while the other used machine learning for more efficient blood donation. For these achievements, Marieke Vinkenoog and Simon Christian Hansmann were awarded the Krijn Rietveld Memorial Innovation Award on Tuesday 2 September.

In an Advance Online Publication biophysicist John van Noort and others show using magnetic tweezers that DNA is folded in compliant helices of chromatin. This allows enzymes access to the DNA needed for gene expression. Van Noort's research group made the discovery in close partnership with researchers…

Smooth platinum electrodes roughen and wear when subjected to repeated cycles of oxidation and reduction, which causes nanometer-scale mounds to grow. Leiden chemists Leon Jacobse and Marc Koper, together with physicist Marcel Rost, discovered the exact details, using a unique tunneling microscope.

Ten Leiden researchers have been awarded a Veni grant by the Dutch Research Council (NWO). The grant, of up to 280,000 euros, will enable them to elaborate their ideas over a period of three years.

Leiden researchers have carried out successful tests using a new method of packaging a cancer vaccine in nano-particles. The new vaccine has induced a strong immune reaction in mice. The researchers believe that this method can make an important contribution to the treatment of cancer. Their findings…

A public symposium was held at Leiden University on 20 February on a hot topic: renewable energy. This is the second time in a year that the University has organised such a symposium. The previous one, about Artificial Intelligence, was a big success.

The electrochemical reduction of a group of organic compounds on platinum is strongly dependent on the arrangement of the atoms in the platinum surface. Christoph Bondue, postdoc in Marc Koper's group, published this in Nature Catalysis on 4 March. The reduction of such compounds is an important process…

A group of single-celled organisms organises its DNA in a similar way to higher organisms such as plants, animals, and fungi. However, the way packaged DNA is read out differs between the two related groups, Bram Henneman discovered. PhD defence on 5 December.

How can we supply the growing world population with sustainable energy? At Laurens College in Rotterdam, Prof. Marc Koper speaks with the students about the crucial role of chemistry in the energy transition. Guest classes like this are a good way for school students to learn about the academic world,…

Discovering effective new drugs is a long, expensive and uncertain process. Laura Heitman wants to improve this by finding out more about how drugs bind to proteins that play a role in disease. She calls it ‘drug discovery 3.0’. Inaugural lecture on 9 December.

A consortium of international researchers comes with a unique solution to the energy problem. By mimicking photosynthesis, they aim to produce sustainable fuels out of sunlight, water, and CO2. Their secret? ‘Soap bubbles’, says Leiden chemist Sylvestre Bonnet, who is part of the consortium.

The Institute of Biology Leiden has a new visiting professor as of the first of May. Bioinformatician Marnix Medema holds the Van der Klaauw chair for a year and looks forward to scientific collaborations and to boost the bioinformatics education.

Cornelia Pabst is a PhD candidate at Leiden Observatory, whose research is based around primary data taken by instruments onboard SOFIA, an airplane-based observatory on which she has flown multiple times. Pabst explains how this airplane has impacted her research career and gives her views on the ever-present…

Pharmacist-clinical pharmacologist Robert Rissmann has been appointed Professor of Translational Dermatology. This extraordinary professorship has been created jointly by the Leiden Academic Centre for Drug Research (LACDR) and the Centre for Human Drug Research (CHDR) to strengthen their partnership…

An all-optical transistor, a molecule-sized sensor and a new kind of single-photon source for quantum communication. All dreamed applications of fundamental physics that are one step closer thanks to Robert Smit. On 12 June, he defended his PhD thesis with distinction.

Leiden University will be conferring three honorary doctorates in its special anniversary year. They will be awarded to Eliot Higgins, truth finder and founder of Bellingcat, Bonnie Honig, expert in feminist theory and legal theory, and Kelly Chibale, professor of organic chemistry, who works on prevention…

Three speakers, three fascinating science stories and a well-filled lecture hall. The Niko Tinbergen Lecture had a successful restart on 10 December 2019.

From bedtime stories about mathematics to podcasts about microplastics and games on weeds: master students from the Science Communication & Society track presented the real-life products they developed during their final presentations on 20 December. Many of the products are already implemented by c…

Several consortia in which Leiden University is involved have been awarded Dutch Research Agenda funding. Leiden is the coordinator of five of these consortia. These five consortia will receive grants worth a total of almost 24 million euros. They relate to interdisciplinary projects that will bring…

Astronomers and surgeons from Leiden are collaborating with industry to develop an optical instrument that delivers faster, more accurate imaging of tumour tissue and abnormal blood flow during surgery.

Both Leon Jacobse and Thom Hersbach from Marc Koper's research group obtained their PhDs cum laude. They both investigated changes on the surface of a platinum electrode. Jacobse studied this at a positive voltage, Hersbach at a negative voltage. Platinum has the potential to convert renewable energy…

An international team of astronomers including Leiden professor Ewine van Dishoeck has observed the benzene molecule (C6H6) in a planet-forming disk around a young star for the first time. The observations tell us more about the forming of planets in this disc, like our own Earth. The scientists publish…

Liposomes – nano-sized spheres composed of fatty molecules – are very promising for vaccination. Bio-pharmaceutical scientist Naomi Benne discovered that the immune response in animal models can be steered by varying the charge of the liposomes. She obtained her PhD degree on 8 September for this research,…

Having a bachelor's, a master's and a PhD in Chemistry, Elena Sánchez López shifted to a more biological field of research for her postdoc. She completed all her studies at the University of Alcala, in Spain, before applying for a LEaDing fellowship at Leiden University, a Marie Sklodowska-Curie Cofund…

Researchers from the Leiden University Medical Center (LUMC) have successfully used stem cell gene therapy to treat a baby with the severe congenital immune disorder SCID. An important milestone: it is the first time stem cell gene therapy of Dutch origin has been administered to a patient, and also…

What’s really happening in the space between the cells in your body? With the Collagen Canvas project, students from Leiden University invite you to explore this question by blending science with art. This interactive artwork immerses you in the dynamics of the extracellular matrix—the invisible structure…

Studying how single DNA molecules behave helps us to better understand genetic disorders and design better drugs. Until now however, examining DNA molecules one-by-one was a slow process. Biophysicists from Delft University of Technology and Leiden University developed a technique that speeds up screening…

An international team of astronomers, led by Will Rocha of Leiden Observatory, using the NASA/ESA/CSA James Webb Space Telescope have discovered that the key ingredients for making potentially habitable worlds are present in early-stage protostars, where planets have not yet formed.

Leiden molecular cell biologists in the research group of Annemarie Meijer have discovered novel early macrophage-specific genes in zebrafish, including a signal transducer pivotal for the migration of macrophages in the innate immune response to bacterial infection. Their findings were published on…

Researchers and clinicians at Leiden University Medical Centre (LUMC) are about to begin a milestone clinical study. It will be the first time a stem cell gene therapy developed in the Netherlands is used in a clinic. The therapy will be used to treat children with SCID, a rare disorder where children…

Six researchers from Leiden University have received an ERC starting grant. This grant of on average 1.5m euros will enable the researchers to launch their own project, form their own research team and develop their best ideas.

The dark matter of biology: clumps of sugar molecules that, for example, form sugary webs around pathogens. We know very little about them. Wouter Remmerswaal threw all his talent into the challenge – both in the lab and as a modeller – and succeeded. He received his PhD on 12th September.

Ton Schumacher, professor by special appointment in Immunotechnology at the LUMC and group leader of Molecular Oncology and Immunology at the Netherlands Cancer Institute, has been awarded the NWO Stevin Prize. The Stevin Prize and the Spinoza Prize are the top scientific prizes in the Netherlands and…

Five researchers from Leiden University have been awarded a Starting Grant by the European Research Council (ERC). This grant of on average 1.5m euros enables researchers who show potential to start their own project, lead a research team and implement their best ideas.

All comets might share their place of birth, new research says. For the first time ever, astronomer Christian Eistrup applied chemical models to fourteen well-known comets, surprisingly finding a clear pattern. His publication has been accepted in the journal Astronomy & Astrophysics.

Electrochemist Marc Koper has been awarded an ERC Advanced Grant of 2.5 million euros for research into chemical reactions driven by electrodes and electricity. He hopes that new insights will make it into the textbooks and help design green processes, such as making fuel from greenhouse gas.

Imagine that you need to travel, but you don’t have a car and you’re dead broke. What do you do? Hitchhiking, of course! Leiden biologists found that certain bacteria use this very same tactic: their spores hop on motile bacteria and use them as a taxi, ensuring they reach the right environment to f…

Humans have influenced nature since as early as the Ice Age, and over the past century man’s impact has become even greater with our many new technologies and a growing world population. Leiden researchers study this impact and how we can keep it within reasonable limits so that nature can be preserved.…

16 April was a special day at the Faculty of Science. In honour of the collaborations with the Chinese partner university, it was declared Xi’an Jiaotong University Day.

The European Research Council (ERC) has awarded an Advanced Grant to six Leiden researchers. It awards these significant grants to established principal investigators for ground-breaking, high-risk research.