Damien Van Puyvelde and Paul Oling explore how government intelligence agencies can effectively collaborate with the private technology sector to meet their evolving technological needs, focusing particularly on emerging technologies such as artificial intelligence (AI) and quantum computing.

Bacteria are highly complex and diverse organisms that have adapted to survive in ecological niches ranging from the most extreme to the most heterogeneous environments.

The Science Council is an advisory committee to the Board of the Institute and consists of the full professors of the Institute.

This dissertation focused on computational methods based on first principles calculations using the Density Functional Theory (DFT) framework. Emphasis was laid on affordable methods that can provide a tradeoff between computational expense and accuracy.

PhD defence

PhD defence

PhD defence

PhD defence

The Chemical Probe Facility is part of the Leiden Early Drug Discovery & Development (LED3) center. Activity-based protein profiling (ABPP) is one of the pillars of chemical biology. ABPP determines the activity of entire protein families in living cells and tissues under physiological conditions, such…

Looking for ways to travel more sustainably once you've reached your destination? Here, we offer some ideas and helpful links to guide you in becoming a more responsible tourist. Ecotourism, defined as "responsible travel to natural areas that conserves the environment, sustains the well-being of…

Twenty years from now, the world population is estimated to be around 9 billion people (now 8 billion). In combination with the improvements in living standards and the corresponding growth in consumption, this population will result in an enormous increase in the demand for food, consumables, water…

Adoptees in the Netherlands generally do not use more medication than their non-adopted peers.

To get a feeling of how we operate at LED3 when it comes to Early Drug Discovery, please browse through our case studies. When you select a case study you’ll find relevant contacts.

Urban, Food, Water, Biodiversity, Resources and Energy: these are the main research topics of the Institute of Environmental Sciences. We always strive to be a global leader in our field. And make a real impact with both our research programmes.

The first index to measure product safety, sustainability, and circularity, operationalising the EU’s (SSbD) framework.

Promotor: E.F. Smets Co-promotor: J. Geml

For thousands of years, societies have fallen under the reign of a single leader, ruling as chief, king, or emperor. In this fascinating global history of medieval and early modern dynastic power, Jeroen Duindam charts the rise and fall of dynasties, the rituals of rulership, and the contested presence…

My artistic practice deals with documents and, more specifically, with the use and the exploration of their narrative potential.

Striga hermonthica, commonly known as witchweed, infests major cereal crops in Sub-Saharan Africa causing severe yield losses and threatening the livelihood of millions of resource poor farmers.

The research programme Industrial Ecology aims to support the ecological transformation of society and environment towards sustainability. The research subject is Industrial Ecology in its broadest definition, covering environmental systems analysis, and incorporating the social and economic aspects…

Hydrogen fuel cells are expected to be pivotal in the energetic transition towards renewable energy sources such as solar and wind power. However, their industrial scalability is severely hindered by the high cost and degradation rate of platinum catalysts, one of their key components. Addressing this…

L1-oral language education is widely regarded as essential for developing communicative competence and critical thinking. However, as a research domain it remains relatively underexplored. The aim of this study was to identify effective elements and challenges within oral language education and to contribute…

Promotor: Prof.dr. M.K. Richardson

This research delves into a region of space known as the interstellar medium (ISM), which is essentially the area between the stars filled with gas and dust.

Leiden is a real student city and has everything you’ll need to turn your time as a student into the time of your life.

The research of the Applied Mathematics cluster is concerned with such diverse topics as dynamical systems, representation theory, differential equations and pattern recognition.

Bacteriophages, or phages for short, are the most abundant biological entity in nature. They shape bacterial communities and are a major driving force in bacterial evolution.

Where did species survive the cold cycles of the current Ice Age?

Understanding the water use of power production is an important step to both a sustainable energy transition and an improved understanding of water conservation measures. However, there are large differences across the literature that currently present barriers to decision making.

Promotor: W.T. de Groot

How did Anglo-Saxons reflect on the experience of growing old? Was it really a golden age for the elderly, as has been suggested?

Promotores: Prof.dr. G.W. Canters, Prof.dr. T.J. Aartsma

Streptomyces are multicellular, Gram-positive bacteria in the phylum of actinobacteria which produce a high amount of bioactive natural products of which the expression is tightly coordinated with the life cycle.

Plants and soils from natural ecosystems harbor great diversity of soil microorganisms, which could potentially contribute to the sustainability of horticulture. The knowledge about using wild plant species and soil from natural ecosystem to improve the crop health will advance the application of ecological…

The demand for neodymium-iron-boron (NdFeB) magnets is rapidly growing, while the neodymium supply chain is under pressure. Recycling can alleviate these issues. This thesis investigates the potential for deploying novel magnet recycling technologies and their environmental consequences.

Human civilization consumes a huge amount of fossil fuels, which has resulted in an atmospheric CO2 level which has not been higher in over 800 millennia.

Vitamin A or retinol is essential in embryonic development, the visual cycle and the immune system.

Surface acoustic waves (SAWs) are mechanical waves that travel along the surface of a material and find many applications in modern technologies due to the ease of excitation on piezoelectric substrates via interdigital transducers (IDTs).

Promotores: Prof.dr. P.M. Brakefield, Prof.dr. B.J. Zwaan (Wageningen Universiteit)

Fungal food spoilage often starts with a contamination with spores. Experimental data strongly indicate the existence of subpopulations of spores with different levels of resistance to preservation methods.

Leiden University is established in two cities: Leiden and The Hague.

How do mycobacteria subvert the defenses of host immune cells?

The electrochemical oxygen reduction reaction (ORR) is an essential half-reaction for the utilization of hydrogen as a sustainable fuel, via the conversion of hydrogen to electrons and protons facilitated by the ORR. In the most common fuel cells, the ORR is requires high loadings of non-abundant platinum…

This dissertation revolves around the design and implementation of novel instrumentation and related measurement techniques, at the single molecule level, for use in biophysical research. Chapter 1 presents an introduction to the field of fluorescence-based single molecule measurements. In particular,…

Changing burial rites in Early Medieval Northern Gaul, 450-600 CE

On 22 June, Chalermwut Sriporm defended the thesis 'Franchising legal frameworks: a comparative study of the DCFR, US law and Australian law regarding franchise contracts'. The doctoral research was supervised by Jacob Hijma and Iris Houben.

Research and design are two activities that are becoming increasingly important in the Dutch subjects O&O (‘research and design’) and NLT ('nature, life and technology’). The dissertation of Tessa Vossen (ICLON and Faculty of Science) indicates that teachers and students understand the importance of…

The role of material production as a driver of environmental impacts is increasing, which calls for a better understanding of global material flows. This thesis explores the role of in-use stocks of products, buildings and infrastructure as a key driver of global material demand and discusses the implications…

Kuba funerary art from the Congo River Basin