Children with autism spectrum disorder experience serious challenges in social functioning, which threatens their development in many areas of functioning.

The symposium is open to all registered participants and consists of a one-day programme and a poster session.

This article devises a framework to assess the degree to which human rights bodies provide duplicating or contradicting recommendations to States. Focusing on the case of torture, it creates an original database of recommendations delivered to 14 countries in the years 2012–2016. Results show that duplications…

During the early modern period, many medieval manuscripts were cut up into strips of parchment which were reused to reinforce the bindings of newly printed books. Until recently, these reused pieces of medieval manuscripts only came to light when the early modern book binding was damaged and/or subjected…

Promotor: F.H.J. Redig, Co-Promotor: W.T.F. den Hollander

If you replace the standard hydrogen atoms in ice with a heavier variant, something odd happens. The volume occupied by the molecules increases by 0.1 per cent. Leiden chemist Jörg Meyer and his colleagues have created a theoretical model that describes this behaviour. Their research appeared on the…

How do plant defense genes get activated?

Which adolescents are more at risk of developing social anxiety disorder later in life?

In Quantum mechanics, particles can be in multiple positions simultaneously. Yet, when a measurement is made, the particle is found only in one place. Technology has come to a point where we may design experiments that will tell us how.

The effects of many treatments are determined, to a significant degree, by factors other than the medicine or treatment itself. For example, placebo effects can be equal to the effect size of for example antidepressants or painkillers. Contributing factors are the trust placed in the doctor, the expectation…

Open online education has become a highly popular method of education. The current project aims to further our knowledge of how open online courses can be best designed to be consistent with human learning mechanics and facilitate meaningful learning.

Glucocorticoids (GCs) are widely prescribed as anti-inflammatory drugs due to their well-established immunosuppressive effects.

Research in the group Clinical Neurodevelopmental Sciences is focused on understanding and influencing developmental mechanisms in children and adolescents.

Miriam Cohen defended her PhD dissertation entitled “Reparations for International Crimes and the development of a Civil Dimension of International Criminal Justice” on 28 June 2017. She wrote her thesis under the supervision of Professor L.J. van den Herik and Professor C. Stahn.

Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda

In this research group, headed by Prof. Erik Danen, the aim is to unravel cellular signaling mechanisms in normal and diseased cells, with a long-standing interest in cell adhesion signaling. In complex multicellular organisms such as ourselves, a division of labor emerges where different tissues and…

Source: PLoS ONE, Volume 10, Issue 3 (2015)

Promotor: M. Ubbink, Co-Promotor: R. T. Dame

This doctoral thesis is an effort to understand how lipid phase-separation induced by diacylglycerol analogues in lipid-based nanoparticles affects their in vivo behavior, leading to specific nanoparticle-protein communications and selective cell targeting.

In this thesis, we aim to shed light on the diverse and often opposing roles of integrin α3β1 in cancer.

‘Schiedsgerichte in den Aussenverträgen der EU. Neue Entwicklungen unter Einbezug der institutionellen Verhandlungen Schweiz–EU’, Jusletter 28 May 2018

Aluminium-based adjuvants, such as aluminium hydroxide and aluminium phosphate, are well-known for their immune-stimulating properties.

To what extent does the Law Ombudsperson for Children achieve its goals as intended by the legislator when introducing the law?

Somatic symptoms, such as pain, itch, and fatigue have been shown to have a bidirectional relationship with mental symptoms. Although acute somatic symptoms serve some adaptive properties, chronic symptoms can instead lead to interference in daily activities and lower quality of life.

We focus on a better understanding of the mechanisms of cancer drug resistance and metastasis.

During the Leiden Science Family Day, you will visit places that are normally closed to the public: go backstage at the Faculty of Science!

The CIGR comprises research groups from the Leiden Institute of Chemistry (LIC), the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institue of Physics (LION).

Why is Crossnational and Cross-cultural agents such as Henrich Carloff and Willem Leyel important when studying Early Modern expansion?

Despite substantial progress in understanding tuberculosis (TB), the eradication of the TB epidemic is still far from reach.

A new computer simulation shows the promising possibilities of the booming field of topology. Smartly designed mechanical structures carry sound exclusively one way and are immune to fabrication errors. Publication on 17 July in Nature Physics.

To be eligible for Physics at Leiden University, you must meet the following admission requirements.

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To be eligible for Research in Physics, theoretical at Leiden University, you must meet the following admission requirements.

To be eligible for Research in Physics, Quantum Matter and Optics at Leiden University, you must meet the following admission requirements.

The availability of complete plant genome sequences together with the ever increasing amount of data on the molecular, cellular and physiological mechanisms of plant development require mathematical and computational models to obtain a complete overview of and generate new insights into the quantitative…

Atoms and molecules are the basic units of matter. If we keep dividing a bar of gold or a glass of water into smaller parts, at the end we are left with a single gold atom or a water molecule.

In a typical glycosylation reaction, a donor is activated to form a (variety of) electrophilic species which can react with a nucleophilic acceptor, following a reaction mechanism having both SN1 and SN2 character.

Promotor: V. Vitelli, Co-promotor: J. Paulose

What is the role of emotion regulation in coping with interpersonal feedback?

The research programme Industrial Ecology aims to support the ecological transformation of society and environment towards sustainability. The research subject is Industrial Ecology in its broadest definition, covering environmental systems analysis, and incorporating the social and economic aspects…

Promotor: G.J. Kramer Co-Promotor: E.G.M. Kleijn

The study of orchid flowers, fruits, and inflorescences is crucial due to the remarkable diversity of orchid species and their unique adaptations to pollinators and seed dispersers. However, our understanding of the evolution and development of these organs within the orchid family remains limited.

In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.