Can the venom of snakes, scorpions and other animals be sources of new antibiotics?

Lecture

best phd theses of the faculty of science Leiden - physics, chemistry, computer science, biopharmaceutical sciences, biology, industrial ecology, environmental sciences, astronomy, mathematics. thesis

Freezing bacteria super fast to gain a true-to-nature image of the internal and external structure. Ariane Briegel Professor of Ultrastructural Biology came to Leiden specially to carry out this research. Leiden University is one of the few institutes in the world to have the necessary equipment. Inaugural…

The current COVID-19 vaccination campaign involves injecting the vaccine into muscle tissue, but injecting a smaller amount of vaccine in the skin might also provide good protection. The #wakeuptocorona crowdfunding campaign has enabled Anna Roukens (LUMC) to examine the safety and efficacy of vaccination…

ACPA PhD Marina Liontou Mochament will host an online workshop in April.

PhD defence

PhD defence

A portrait of the complex historical process of over 500 years of European colonialism in the New World.

Nanoparticles can be used as delivery systems for both small molecules and macromolecules such as proteins, peptides or oligonucleotides. This thesis focuses on the use of liposomes, nanometric vesicles formed by a lipid bilayer enclosing an aqueous core. Liposomes are highly versatile delivery syst…

Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt

How does invasive hybridization affect threatened native species?

Promotor: G.P. van Wezel, Co-promotor: Y.H. Choi

Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée

The company Azafaros was established in 2018 to translate innovative science from Leiden University and Amsterdam University Medical Center into novel disease-modifying treatment modalities for rare genetic metabolic disorders such as lysosomal storage diseases.

In this article, Dimiter Toshkov aims to explains the gender gap in COVID-19 vaccination attitudes.

Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot

The CMCB brings together microbial cell biology expertise in Leiden. It aims at optimal resonance between the groups and maximal exploitation of the available infrastructure and to develop innovative cross-boundary technology platforms.

Glycoconjugate vaccines are composed of microbial poly- or oligosaccharides covalently linked to a carrier protein.

New or improved treatments for chronic and acute illness.

Dr. Foks obtained this fellowship for the project “Can promotion of efferocytosis induce regression of atherosclerosis?”, in which she aims to identify novel targets to promote regression of atherosclerosis. This research grant allows her to initiate independent research for the next three years.

We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.

PhD student Wen Yang discovered how certain cell receptors in E. coli bacteria signal 'smells'. With the use of ice-cold electron microscopy microbiologists from Leiden gain more insight into how bacteria respond to their environment. Publication in mBio.

Research at the BIOSYN group is comprised of the following research themes:

During the Leiden Science Family Day, you can take part in various workshops. You can also watch various demonstrations. Where will you go?

Through his project we will unravel the global regulatory networks that control gene expression in Streptomyces bacteria and allow them to properly respond to major changes in the environment; we will then harness this knowledge to activate and identify novel antibiotics

Nanoparticles exhibit a number of adjustable properties, e.g., their size, shape, and surface and core chemistry, which can be further diversified with different functional moieties. This opens a broad field for application in diagnostic and therapy. In this respect, the use of a polymeric hybrid material,…

Atherosclerosis (thickening of the artery wall) is the most common cause of heart attacks or strokes, and one of the most common causes of death in the western world. People with this condition have to take medicine all their lives, so a vaccine for atherosclerosis would be a breakthrough.

Molecular Physiology is a research group at the Leiden Institute of Chemistry dedicated to the design, synthesis and application of chemical tools to study important biological and biomedical questions. The group is headed by Prof. Dr. Mario van der Stelt and includes the research lines of Assistant…

The Delivery of Biotherapeutics research group is led by Prof. Matthias Barz and focusses on the synthesis and characterization of polypept(o)ids and their application in nanomedicine to improve existing therapies or enable novel diagnostic or therapeutic approaches.

In order to gain insight into the structure and function of the molecular complexes involved in chemotaxis, we use electron cryotomography (ECT). This technique allows us to directly study microbes in their native state at resolutions capable of visualizing individual proteins.

The central question of this Vici proposal is to investigate if, and how actinobacteria exploit life without a cell wall.

From self-driving cars to innovative drug development: artificial intelligence (AI) will fundamentally change our lives in many different ways. We study this technology at a deep and fundamental level. And we seek answers to questions about liability and privacy, for example. Our researchers from…

The Biomedical Sciences Health specialisation aims to provide you with a theoretical background and academic competences in multidisciplinary research in Biomedical Sciences and in clinical practice in Medicine. Since the programme is partly taught in English and partly in Dutch, fluency in Dutch is…

The Biomedical Sciences research specialisation aims to provide you with a theoretical background and academic competences in multidisciplinary research in Biomedical Sciences. The entire programme is taught in English.

The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterise and predict variation in treatment response and enhance translational drug development strategies.