PhD defence

A portrait of the complex historical process of over 500 years of European colonialism in the New World.

Nanoparticles can be used as delivery systems for both small molecules and macromolecules such as proteins, peptides or oligonucleotides. This thesis focuses on the use of liposomes, nanometric vesicles formed by a lipid bilayer enclosing an aqueous core. Liposomes are highly versatile delivery syst…

Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt

How does invasive hybridization affect threatened native species?

Promotor: G.P. van Wezel, Co-promotor: Y.H. Choi

Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée

The company Azafaros was established in 2018 to translate innovative science from Leiden University and Amsterdam University Medical Center into novel disease-modifying treatment modalities for rare genetic metabolic disorders such as lysosomal storage diseases.

In this article, Dimiter Toshkov aims to explains the gender gap in COVID-19 vaccination attitudes.

Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot

The CMCB brings together microbial cell biology expertise in Leiden. It aims at optimal resonance between the groups and maximal exploitation of the available infrastructure and to develop innovative cross-boundary technology platforms.

Glycoconjugate vaccines are composed of microbial poly- or oligosaccharides covalently linked to a carrier protein.

New or improved treatments for chronic and acute illness.

Dr. Foks obtained this fellowship for the project “Can promotion of efferocytosis induce regression of atherosclerosis?”, in which she aims to identify novel targets to promote regression of atherosclerosis. This research grant allows her to initiate independent research for the next three years.

We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.

PhD student Wen Yang discovered how certain cell receptors in E. coli bacteria signal 'smells'. With the use of ice-cold electron microscopy microbiologists from Leiden gain more insight into how bacteria respond to their environment. Publication in mBio.

What is the Fine Mechanical Department?

An interdisciplinary team of Leiden researchers has discovered that wasting syndrome, a severe byproduct of tuberculosis, is the same for all humans and animals studied. The discovery offers new opportunities to investigate the still insufficiently understood condition. The scientists also developed…

Research at the BIOSYN group is comprised of the following research themes:

During the Leiden Science Family Day, you can take part in various workshops. You can also watch various demonstrations. Where will you go?

Through his project we will unravel the global regulatory networks that control gene expression in Streptomyces bacteria and allow them to properly respond to major changes in the environment; we will then harness this knowledge to activate and identify novel antibiotics

Nanoparticles exhibit a number of adjustable properties, e.g., their size, shape, and surface and core chemistry, which can be further diversified with different functional moieties. This opens a broad field for application in diagnostic and therapy. In this respect, the use of a polymeric hybrid material,…

Atherosclerosis (thickening of the artery wall) is the most common cause of heart attacks or strokes, and one of the most common causes of death in the western world. People with this condition have to take medicine all their lives, so a vaccine for atherosclerosis would be a breakthrough.

Molecular Physiology is a research group at the Leiden Institute of Chemistry dedicated to the design, synthesis and application of chemical tools to study important biological and biomedical questions. The group is headed by Prof. Dr. Mario van der Stelt and includes the research lines of Assistant…

The Delivery of Biotherapeutics research group is led by Prof. Matthias Barz and focusses on the synthesis and characterization of polypept(o)ids and their application in nanomedicine to improve existing therapies or enable novel diagnostic or therapeutic approaches.

In order to gain insight into the structure and function of the molecular complexes involved in chemotaxis, we use electron cryotomography (ECT). This technique allows us to directly study microbes in their native state at resolutions capable of visualizing individual proteins.

The central question of this Vici proposal is to investigate if, and how actinobacteria exploit life without a cell wall.

From self-driving cars to innovative drug development: artificial intelligence (AI) will fundamentally change our lives in many different ways. We study this technology at a deep and fundamental level. And we seek answers to questions about liability and privacy, for example. Our researchers from…

The Biomedical Sciences Health specialisation aims to provide you with a theoretical background and academic competences in multidisciplinary research in Biomedical Sciences and in clinical practice in Medicine. Since the programme is partly taught in English and partly in Dutch, fluency in Dutch is…

The Biomedical Sciences research specialisation aims to provide you with a theoretical background and academic competences in multidisciplinary research in Biomedical Sciences. The entire programme is taught in English.

The ‘Contagious!’ exhibition was set to open at Rijksmuseum Boerhaave in April but had to be postponed because of the corona crisis. The museum hasn’t been twiddling its thumbs in the meantime. The exhibition will now open on 16 July, and the corona crisis has a major role.

The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterise and predict variation in treatment response and enhance translational drug development strategies.

Bioprinters that enable scientists to engineer complex tissues and organs. It sounds like science-fiction, but not for the scientists of the Alireza Mashaghi lab at the Leiden Academic Centre for Drug Research. The lab has recently been equipped with two state-of-the-art bioprinters: BioX and LumenX+.…

With the passing of Henk Jan de Jonge on 16 April 2022, Leiden University has lost one of its most characteristic, learned and devoted professors.

Professor Annemarie Meijer and several students explained to more than 8000 visitors the zebrafish as a model for research during the National Weekend of Science (3-4 Oct) at Science Center NEMO in Amsterdam.

PhD defence