In Reframing the Diplomat Albertine Bloemendal offers a unique window onto the unofficial dimension of Cold War transatlantic relations by analyzing the diplomatic role of the Dutch Atlanticist Ernst van der Beugel as a government official and as a private diplomat.

The territories that would make up what is today the Republic of Zambia officially became British in 1891. However, this did not equate to an on-the-ground presence of colonial authority capable of affecting the destiny and daily lives of people.

In this chapter, Linde Desmaele & Luis Simón examine NATO’s strategic adaptation since Russia’s annexation of Crimea in 2014.

Microscopic insight on lipid-based nanomedicine in vivo remains limited to the perception of the knowledge that could be obtained: if we interpret only what we see, then we only believe to know. Although believing to know encapsulates an undefined amount of uncertainty in the exploration of lipid-based…

This book explores the reception of foreign news during the late sixteenth-century civil wars in France and the Netherlands.

Japan's Occupation of Java in the Second World War draws upon written and oral Japanese, Indonesian, Dutch and English-language sources to narrate the Japanese occupation of Java as a transnational intersection between two complex Asian societies, placing this narrative in a larger wartime context of…

Robert Pee, William Michael Schmidli (Eds.) This book posits that democracy promotion played a key role in the Reagan administration’s Cold War foreign policy.

Does foreign aid promote human rights?

Potential drugs that seem promising in the lab, but don’t show any activity in a person: they cost the industry an incredible amount of time and money. That’s why Indira Nederpelt focuses on a more efficient search for new drugs in her PhD, by determining the kinetics of a potential drug earlier on…

Laura Heitman has been awarded a VIDI grant for her innovative drug research. Heitman strives to optimize a drug’s binding kinetics at its target in order to ultimately fight diseases effectively. She even pleads for a paradigm shift in drug discovery.

Currently, more than 80% of drugs are used in an off-label manner in critically ill neonates.

In this article, Thomas Maguire, assistant professor at the Institute of Governance and Global Affairs, examines the intelligence of the US, British and Ukrainian governments and NATO partners concerning Russia and its war against Ukraine. This article discusses how and why governments communicate intelligence…

On 4 May, Leiden University remembered the victims of the Second World War from our university community. Alumni, students and present and former staff of the University came together for this Hour of Remembrance.

Southern Crossings: Indian activists and the Afro-Asian movement in the early Cold War era

Emily Wolff, PhD candidate at Leiden University, wrote a paper about the inclusion of imperial citizens in the Dutch post-war welfare state.

In the search for new medicines against diseases such as cancer, a Leiden team has developed a new workflow. This approach combines artificial intelligence (AI) with molecular modelling and is suitable for finding unknown and innovative drug structures, the researchers proved.

In this article, Thomas Maguire, Assistant Professor at the Institute of Security and Global Affairs, examines why states use intelligence to influence external audiences.

Schuurman examines how Russia is escalating its covert operations against European countries.

Leiden chemists have developed a new technique with which they can determine the role of kinases – a group of proteins – in a living cell. This technique makes it easier to find new drug targets for diseases such as cancer and rheumatoid arthritis. The team published the findings in the journal Nature…

Jacques Waisvisz (98) is one of our oldest living alumni. As a Jewish student in the Second World War, he was forbidden from completing his studies. How does he look back at that time, and what was life like afterwards? ‘No one thought that the situation here would become so bad.’

Medical drugs are expensive to make and can have an adverse effect on the environment. Researchers Stefano Cucurachi and Justin Lian have developed a framework to help the healthcare system assess the economic and environmental sustainability of medical compounds.

How were Spanish commanders fighting in the Low Countries between 1567 and 1577 portrayed in Spanish and Dutch narrative sources during the Eighty Years War?

Molecular Physiology is a research group at the Leiden Institute of Chemistry dedicated to the design, synthesis and application of chemical tools to study important biological and biomedical questions. The group is headed by Prof. Dr. Mario van der Stelt and includes the research lines of Assistant…

How do you know if a drug will actually work? The Leiden-based spin-off Omivera is developing a new technology that could provide clearer answers. The young company received a seed investment from the investment fund UNIIQ to support its development.

We aim to gain a better understanding of the natural disease progression of ALS in order to improve clinical trial design and analysis and to support drug discovery and clinical development of new drugs.

This book describes the different approaches for drug delivery to the brain with an emphasis on the physiology of the blood-brain barrier (BBB) and the governing principles and concepts for drug delivery across the BBB

Odile Bodde tells about her stay in London at King's College...

This book closely analyses the rise and fall of Louis XIV's marine insurance institutions in Paris, which were central to the French monarchy's efforts to stimulate commerce, colonial enterprise and economic growth.

Utilizing the polymeric platform of polypept(o)ides, this thesis describes synthesis and investigation of novel triblock copolymers to obtain carrier systems with multiple compartments for efficient siRNA delivery. Although the individual microstructure of nanoparticles differs depending on the polymeric…

How do first-hand narratives of war of commanders in the front line relate to the official narrative of the Eighty Years’ War?

Students were able to continue their studies in September 1945 after the University had been closed for several years during the Second World War. This moment was celebrated for four days, with the traditional cortège, commemorative services and a party in the Botanical Garden. Queen Wilhelmina was…

The chain that supplies patients with new medicines consists of various complex links: from fundamental research to clinical tests and production. This entire chain is represented in Leiden. Leiden University, the Leiden University Medical Center (LUMC), and the companies on the Leiden Bio Science Park…

Two Stolpersteine (stumbling stones) have been placed in front of the University Library in memory of the Jewish Cosman family. At the time of the Second World War, they lived in one of the houses where the library is now located.

The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.

Pharmacy undergraduate education at Leiden Pharmacy combines the strong scientific foundation of the bachelor programme Bio-Pharmaceutical Sciences with experience-based learning and a strong focus on pharmaceutical patient care and pharmaceutical treatment in the master programme Pharmacy.

Leiden researcher Ethan Mark has a mission, he explains in the alumni magazine Leidraad. He wants us to take off our Eurocentric glasses when we study the Second World War. We have focused on ourselves for far too long; after 75 years, it’s about time we listened to stories from the rest of the worl…

On 1 June 2022, Bruno Braak defended his thesis entitled 'Overcoming ruptures: Zande identity, governance, and tradition during cycles of war and displacement in South Sudan and Uganda (2014-2019).' The doctoral research was supervised by Prof.dr. J.M. Otto, Dr.ir. C.I.M. Jacobs, and Dr. C. Leonardi…

Four years of protracted negotiations and bitter warfare passed between the declaration of Indonesian independence on 17 August, 1945, and the official transfer of sovereignty on 27 December, 1949.

Microneedle-based vaccination has several advantages over vaccination by using conventional hypodermic needles.

What makes peace missions succeed or fail? Which new technologies will determine the outcome of wars? In recent decades, insufficient use has been made of knowledge of modern warfare, when this is crucial to European security. This is what Frans Osinga, Professor by Special Appointment of War Studies,…

Leiden chemical biologists led by Dr Mario van der Stelt have developed a method to facilitate the search for new drugs. This method has allowed them to take an important first step in the development of a drug against obesity.

Finding structure in disordered proteins and developing drugs for undruggable diseases: it might sound like mission impossible, but pharmacologist Alireza Mashaghi and his team are right on top of it. Their project was awarded by NWO through the Open Competition Domain Science -XS, a competition that…

This thesis investigates a pharmacological challenge model induced by Toll-like receptor 7 (TLR7) activation, focusing on skin inflammation and its implications for early drug development.

These days we do not just have wars and civil wars – more of a global civil war, says Bashir Azizi, who received a PhD in April 2020 for his thesis on global citizenship. The second edition of his thesis was recently published.

Nuclear Magnetic Resonance (NMR) Spectroscopy is a non-destructive analytical technique that is used to study the nature and characteristics of molecules with an atomic level precision. It has a wide range of applications especially in synthetic chemistry, biological and biochemical research groups…

Researchers from Leiden University Medical Center (LUMC) and the Leiden-based biotech company Ncardia have joined forces to develop a new platform that enables the automated production of 3D cardiac microtissues. This platform will allow large numbers of drugs to be tested quickly

How can we prevent drug-induced liver and kidney damage? PhD candidates Marije Niemeijer and Lukas Wijaya investigated what happens in the cells during the onset of this damage: a stress response. Both focused on a different subtopic and made some interesting discoveries.