A new technique using fluorescent imaging to track the actions of enzymes might aid drug design for new anti-cancer, inflammation and kidney disease treatments. Researchers at the University of York and Leiden University have published these findings in Nature Chemical Biology.

Hundreds of thousands of Dutch people suffer from pain caused by knee osteoarthritis and the number is rising fast. Prof. Jaap Harlaar specialises in clinical biomechanics. His research is helping improve osteoarthritis treatment. Harlaar has been appointed Medical Delta Professor and now holds posts…

For the International Day of Women and Girls in Science, women students and researchers from physics talk about what inspires them about their work. From quantum to cosmology and biophysics, their curiosity about how nature works is what connects these women. What do these 5 scientists want to share…

This project on the role of FoxPs in vocal perception and production learning is part of nine PhD-positions funded by the NWO Gravitation Programme which was granted to the Dutch Research Consortium 'Language in Interaction'

The question of land property titles is a common source of conflict between indigenous communities and federal authorities all over the Americas. A new Panamanian law have led indigenous communities to reach out to archaeologist Dr Natalia Donner. A grant from the Centre for Indigenous American Studies…

A microscope with incredible sharpness that leaves samples unharmed – Guido Stam helped develop one. During his PhD research, he combined light and electrons to study biological samples. ‘We can now measure things that simply weren’t possible before.’

A soap film with chemically distinct sides: it's the latest breakthrough in the research led by chemist Sylvestre Bonnet. This unique soap film, along with an innovative device capable of continuously producing new soap films, forms a crucial piece in the puzzle for the development of artificial pho…

How do opinions form and change in large groups of people? That's not just a sociological question, it's a mathematical one. PhD candidate Federico Capannoli studied opinion dynamics. He defended his thesis on November 19.

How do you ensure that a drug has an effect on the right protein – and nothing else? Chemist Anthe Janssen explored various methods for determining the selectivity of potential medicines. He also looked at the substance BIA 10-2474, after a man died in a French clinical trial in 2016. PhD defence on…

The first of April was the official start of Phase II of the collaborative “PCAD4Cod”-project on the effect of sound on fish populations. Hans Slabbekoorn, associate professor at the IBL, is the principal investigator and collaborates with three PhD-students, Dr. Erwin Winter, (Wageningen Marine Research),…

Whether a microbe is beneficial or harmful to a plant can now be predicted with high accuracy thanks to bacLIFE. This bioinformatic tool with an intuitive interface makes it much easier to unlock the secrets of bacterial genomes. A group of Leiden biologists presented it in Nature Communications.

Lotje Zuur sometimes has to perform disfiguring operations. As a head and neck surgeon, she removes parts of the mouth, throat or face of people with cancer. Now a promising treatment may make such operations unnecessary. What would this mean for patients? This is what her inaugural speech on 19 September…

By measuring proteins in tears, ophthalmologists can more easily diagnose dry eyes (Dry Eye Disease). Peter Raus, a Belgian ophthalmologist and PhD student at the Institute of Biology Leiden, developed a new method for protein determination in tear fluid. The technique is also promising for the early…

Newts of which half of the offspring die before birth. Evolutionary biologist Ben Wielstra is investigating how this can exist in nature. In his research he collaborates with Naturalis Biodiversity Center.

Hans Slabbekoorn is specialised in animal sounds. On 1 July, he was appointed professor of Acoustic ecology and behaviour. A great honour, according to the new professor. ‘This job never gets boring, whether I am investigating the urban jungle or marine noise.’

There are more molecules that could conceivably be candidate drugs than there are stars in the universe. How can we ever efficiently identify those molecules? Professor of AI and Medicinal Chemistry, Gerard van Westen: ‘I’m going to use artificial intelligence as the co-pilot to make an automated search.’…

What are the often invisible cognitive consequences of multiple sclerosis? Maureen van Dam mapped these out during her doctoral research. 'People usually notice the physical symptoms, but the cognitive symptoms deserve at least as much attention.'

Ben Wielstra strives to unravel the evolution of balanced lethal systems. On 1 February he started his own lab at the Institute of Biology Leiden. Wielstra is one of five researchers at Leiden University who has been awarded an ERC Starting Grant in 2018 by the European Research Council. ERC Starting…

In FameLab contestants explain their research to the public in a three-minute presentation – without using PowerPoint or other presentation tools. The Leiden heats of this international communications competition will be held on 7 March. Anyone is welcome to come and watch!

Delft, Nov. 15th, 2022 – Today, eight professors were simultaneously inaugurated as ‘Medical Delta professors’ at Leiden University, LUMC, TU Delft, Erasmus University and/or Erasmus MC. With an appointment of two or more of these five academic institutions, they combine technology and healthcare in…

Thanks to a clever research method, progress is being made in the quest for better tuberculosis medications. Within an American consortium that received a 30 million dollars grant, Leiden researcher Rob van Wijk plays a significant role. ‘The next breakthrough in tuberculosis research will come much…

The adventure of iGEM Leiden has come to an end. The result: prizes for Best Therapeutic Project and Best Model, a gold medal, a successful crowdfunding campaign and of course their open-source research findings, which are available for the scientific community.

Humans have influenced nature since as early as the Ice Age, and over the past century man’s impact has become even greater with our many new technologies and a growing world population. Leiden researchers study this impact and how we can keep it within reasonable limits so that nature can be preserved.…

With his dance routine and YouTube clips, he even manages to make grammar fun. His infectious enthusiasm and innovative teaching methods have won Thijs Porck, a lecturer in Old and Middle English, a nomination for the LUS Teaching Prize.

A team of researchers has managed to recreate the most natural skin cream in existence. Using the DUBBLE beamline (Dutch Belgian Beamline) at the European Synchrotron Radiation produced on the basis of the information identified, has the same properties as vernix caseosa. This cream may have a therapeutic…

Moving an electron microscope of 2000 kg is a delicate challenge. The highly sensitive instrument needed to be moved to a new measurement hall, but even a tiny bump could damage it. After a few nerve-racking weeks of preparing the move and reinstalment, the researchers finally have a verdict: the instrument…

Joost van den Vondel is considered to be the greatest Dutch poet and playwright of his time, but he certainly wasn’t the most popular. The 17th- and 18th-century public preferred to watch ‘Spanish theatre’. University lecturer Olga van Marion has written a book about this, together with Frans Blom (University…

Professor of Ecotoxicology Martina Vijver had planned an eight-week field work course for her students, but the corona virus threw a spanner in the works and Vijver had to come up with a new plan at short notice. ‘Without the help of my own network and that of my colleagues this would have been very…

Discovering effective new drugs is a long, expensive and uncertain process. Laura Heitman wants to improve this by finding out more about how drugs bind to proteins that play a role in disease. She calls it ‘drug discovery 3.0’. Inaugural lecture on 9 December.

Bringing together institutes and research groups, how do you do that? The Faculty of Science set up a joint research theme and financed three PhD positions. After four years, the profiling programme Endocannabinoids expires. ‘It really brought us together, and the collaborations remain.’

Fungi living in vanilla plants play a role in the development of the taste and smell of vanilla, according to Shahnoo Khoyratty of the Institute of Biology Leiden. PhD defence on 27 October.

Interview with Pieter Slaman who received the LUS Education Prize. What makes the award so special to him and does he already know how he will use his prize money?

How do fats and enzymes in the brain contribute to multiple sclerosis? In his PhD research, Daan van der Vliet combined chemistry and neuroscience to gain new insights into how brain disorders develop.

Leiden ecotoxicologist Martina Vijver helped shake a European policy proposal in a single weekend. Not with a new experiment, but with years of research on pesticides – and an urgent letter that reached Brussels.

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In his biography about Professor Rudolph Cleveringa, Kees Schuyt adds to the image we already have of this famous Leiden professor. The overriding focus is generally on Cleveringa’s protest speech against the Nazis, while his later Resistance work carried much greater risks. And we also shouldn't forget…

From molecular ping-pong to cassava in the Amazon, and from extraterrestrial life to special antibodies. Twenty-five researchers from Leiden University have been awarded a Veni grant from the NWO. A grant of up to 250,000 euros will give them the opportunity to further elaborate their own ideas over…

On Thursday November 15th, Leiden University organizes its Physics & Astronomy Ladies' Day for female high school students. To mark this festive day, we put the spotlight on five female researchers, who talk about their experiences working in science.

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