826 search results for “lysosomal strong disorder” in the Public website
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Migraine@Work: work ability in employees with migraine
This study aims to answer two main research questions: (1) What are the main predictors of work ability in employees with migraine? (2) Can we optimise work ability in employees with migraine using a web-based intervention focused on these relevant predictors?
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Research
Research in the group Clinical Neurodevelopmental Sciences is focused on understanding and influencing developmental mechanisms in children and adolescents.
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Fundamental research: Underlying mechanisms of disease and health
To make the right clinical decisions or develop effective diagnostic tests and treatments, it is important to understand the underlying mechanisms of a condition or behavior.
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Overstimulated? Artist pictures her brain with cacophony of colours
'With this artwork, I want to give the audience a glance into my overstimulated brain and that of other people with autism', says Jasmijn den Hoed. The Faculty of Social and Behavioural Sciences is exhibiting her artwork 'Overstimulated' in the restaurant near the blue wall during Autism Week 25 March…
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New impulse for autism research in collaboration with China
Psychologists of Leiden University and Peking University will collaborate to investigate the deficiencies in emotion recognition in children with Autism Spectrum Disorder (ASD). The new collaboration fits very well in the policy of Leiden University in which intensified collaboration with China has…
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Cooperation is improving autism treatment
There are effective treatments for people with autism, says Wouter Staal, professor of Autism Spectrum Disorders, in his inaugural lecture on 4 May. However, it is not yet clear which treatment is most effective for which individual.
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Topologies and convergence structures on vector lattices of operators
This thesis consists of three papers that are centered around the common theme of Hausdorff uo-Lebesgue topologies and convergence structures on vector lattices and on vector lattices and vector lattice algebras of order bounded operators.
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Social Anxiety and Normal Development
Why does social anxiety increase in adolescence and how does it grow out of control in some adolescents?
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Topic: Persistent physical symptoms
Persistent somatic symptoms are long term symptoms that lack a clear medical explanation. These symptoms have a high prevalence where most people know someone who experiences such symptoms or they experience such symptoms themselves. Symptoms can vary greatly in and between people. While one person…
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People and Projects
Our team consists of the following members.
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Programme structure
The research master's specialisation Clinical and Health Psychology consists of five main parts: the general courses, the track-specific courses, the elective courses, a research internship and a thesis.
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How do we deal with the messy reality of psychiatric diagnoses?
Depression or ADHD? Neatly delineated diagnoses fail to do justice to the infinitely complex reality that they refer to, argues Eiko Fried in a new paper for JAMA Psychiatry. His proposal: to map the underlying mechanisms of mental health problems using a Mental Health Atlas.
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How to hijack natural destruction in cells: ‘We need to understand it through and through’
Destroying proteins from the Golgi apparatus of the cell in a controlled manner. That is the focus of chemist Marta Artola’s pioneering research. By developing a groundbreaking technology to target specific proteins in the Golgi, Artola aims to unlock new ways for drug development. For this ambitious…
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BioTherapeutics
Research in the BioTherapeutics research programme is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.
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Our projects
Within Brave Little Ones, we work on several projects to support young children who are prone to anxiety or shyness. We focus on early identification of anxious behavior, as well as on supporting parents in how to respond to and manage this behavior.
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Brave Steps
A step-by-step approach to building confidence in anxiety-prone young children.
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Respiratory health and disease in the Netherlands
Studying the impact of urbanisation on the respiratory health of past Dutch populations (1200-1850 CE).
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Topic: Movement and mental functions
Our ability to learn and control movements is essential for engaging in goal-directed behaviour. From buttoning your shirt and driving a car, to cooking dinner and brushing your teeth -- our actions in daily life rely on this ability.
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Stimulating eye-contact in a virtual environment
Can a virtual character’s friendly non-verbal responses stimulate eye-contact in individuals with varying levels of social anxiety?
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Changing minds in social anxiety: A developmental network approach to neurocognitive bias modification
Which adolescents are more at risk of developing social anxiety disorder later in life?
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The SMILE study: Sleep Mood lntervention: Live Effectively a group intervention in students with sleep problems
Can SMILE, our multi-component intervention, which combines cognitive-behavioural therapy for insomnia, mindfulness, stress, and lifestyle components, improve sleep quality? Can it also improve mood and quality of life and prevent depression and anxiety in the long term?
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Topic: Novelty and enrichment
One of the most crucial aspects of our behaviour is our motivation to explore novel environments and interact with new people. This became painfully clear during the COVID-19 lockdowns, when many people suffered from lack of new experiences and real-life social interactions. The relevance of novelty…
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Career prospects
A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers. However, there are far more graduates than vacancies, especially in mental health care, and competition is therefore fierc…
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Cool Little Kids
In the ‘Cool Little Kids’ research project, we investigate a parenting program that focuses on the prevention of the development of anxiety problems in young, anxiety-prone children.
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Putting a spin on it: amyloid aggregation from oligomers to fibrils
This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.
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On the geometry of demixing: A study of lipid phase separation on curved surfaces
Like a mixture of oil and water, lipid membranes separate into two liquid phases.
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Imperfections: using defects to program designer matter
Errors are everywhere, and mechanical failures are especially common: buckled grain silos and cracked support columns are, justly, seen as an issue to be avoided.
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Hysterons and pathways in mechanical metamaterials
Mechanical metamaterials are carefully engineered materials whose properties are controlled by their structure, not by their composition, which allows using metamaterials to study and control physical effects in detail.
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Non-Abelian metamaterials: emergent computing and memory
In the traditional theory of linear elasticity, superposition dictates that the response of a material does not depend on the sequence of the applied mechanical actuations.
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Translational Neuroscience
Within the LUMC medical research profile Translational Neuroscience innovative multidisciplinary research is performed on a number of severe disorders of the brain, nerves and muscles.
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Topic: Work and health
The research connected to this topic is related to Work and health.
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Hye Kyong Kim
PhD at the Natural Product Laboratory, Institute of Biology, Leiden University - the Netherlands
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Genetic risk & atypical development: 22q11 Syndrome
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Facing social anxiety and avoidant personality disorder
PhD defence
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Activity-based protein profiling for drug discovery
Activity-based protein profiling (ABPP, also termed chemical proteomics), is one of the pillars of chemical biology, and at LED3 we have taken it to the next level. ABPP allows the assessment of protein function in live cells and tissues, which means that the activity of a complete protein family can…
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Psychologists receive grant for social anxiety research
“We are proud and happy to receive this grant. It will enable us to do truly innovative fundamental research with a direct link to practical applications.” Michiel Westenberg is looking forward to investigate the effects of age and social anxiety on eye-contact. Together with Esther van den Bos he has…
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Why avoid my gaze?
Individuals suffering from social anxiety disorder (SAD) consistently avoid eye contact. However, in a non-clinical population, gaze avoidance in socially anxious individuals depends on social situations, Jiemiao Chen saw in a series of experiments, for which she used wearable eye-trackers. On 25 April…
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Student experience
Lifelong learning | “Even though we were spread across five continents, there was a strong sense of connection.”
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After graduation
Psychology graduates acquire skills useful in a variety of jobs. Whether helping people with mental disorders, researching the brain or deciding who should be hired at a company, psychologists can do it.
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Clinical Psychology (English-taught) (MSc)
In the specialisation Clinical Psychology, part of the Master in Psychology, you gain extensive knowledge on the asessment and treatment of mental disorders.
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LIBC Sylvius Lectures
Our lectures are open to anyone with an interest Find your inspiration for interdisciplinary research
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Festive opening of the college year in The Hague: strong ambitions for the new year
How can we make sure that The Hague becomes even more of a city of education and knowledge? This was the theme during the festive opening of the college year in The Hague on 30 August. Filled with ambition, representatives from all The Hague's educational institutions, the municipality of The Hague…
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Scientists find strong evidence that wasting syndrome is the same for all organisms
An interdisciplinary team of Leiden researchers has discovered that wasting syndrome, a severe byproduct of tuberculosis, is the same for all humans and animals studied. The discovery offers new opportunities to investigate the still insufficiently understood condition. The scientists also developed…
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Coffee with Gert and Niels: ‘Positive results, strong growth and new challenges’
The balance is positive: the faculty is growing faster than expected, reserves have been built up, and new programmes are attracting many students. At the same time, rapid growth requires realistic budgets, targeted staff expansion and agility in changing circumstances.
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Real-life data ask for strong algorithms: Mitra Baratchi designs them
How do we deal with large sources of greenhouse gases? Do schools provide a socially-inclusive environment for all children? And how can we protect Earth’s nature? These questions have two things in common: they are complex global challenges, and data can help answer them. Mitra Baratchi is computer…
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Fact or fiction: people with autism never make eye contact
There's a myth that people with autism avoid eye contact in conversations. This can come across as indifferent. Unjustified, stresses Jiayin Zhao, who is doing her PhD research on the socio-emotional development of children with autism. 'That people with autism don't care is anything but true.'
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Social anxiety in adolescents
Serious forms of anxiety concerning other people’s opinions can hinder teenagers at school in social interactions or carrying out tasks. Psychologist Anne Miers is looking for ways to reduce this so-called ‘social anxiety’.
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Preventive Intervention Team
Leiden University neuropsychologists have shown that customised intervention pays off. A new fundamental research-based approach in children who are in danger of going off the rails has delivered spectacular results.
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More efficient learning thanks to sleep
Young children, adolescents and students may experience learning difficulties as a result of lack of sleep. Dr Kristiaan van der Heijden investigates sleep problems and solutions for various age groups.
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United States
This is an Erasmus+ International Credit Mobility project of Leiden University Medical Center with Boston Children’s Hospital in the USA.