1,783 search results for “ab de and exploitation” in the Public website
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‘How can we translate the language of cells into cancer therapies?’
On 23 April 2021, Professor Alfred Vertegaal from the Department of Cell and Chemical Biology at the Leiden University Medical Center (LUMC) delivered his inaugural lecture ‘Unraveling and exploiting cellular communication codes’. Vertegaal used the opportunity to describe how research in the field…
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Leiden Leadership Lunch – Uncertainty and innovation in the social domain: The role of leadership
What opportunities does uncertainty offer with regard to innovative behaviour of professionals and what role does leadership play in this?
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Digitalisering verdient plek op de verkiezingsagenda
Digitalisering raakt iedereen, maar speelt nauwelijks een rol in verkiezingsdebatten. In een opiniestuk in de Volkskrant pleit Reijer Passchier, universitair docent staatsrecht en hoogleraar digitalisering aan de OU voor politieke urgentie en visie op digitale vraagstukken.
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Wouter Kalf and Museum de Lakenhal
On Tuesday 7 December, Wouter Kalf gave a lecture on how All Knowlegde starts with intuïtions for the Studium Generalis series co-hosted by the Museum de Lakenhal. The lecture was in Dutch.
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Article in 'de Volkskrant' by Adriaan Bedner
Adriaan Bedner wrote an article on the relationship between Indonesia and the Netherlands in 'de Volkskrant' of 21 November 2016.
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Huub de Groot breaks down artificial photosynthesis
In a promotional video for the SUNRISE initiative, prof. Huub de Groot explains the impact and ideas behind artificial photosynthesis.
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H2OLAW conference: Law-science interfaces within the law of the sea and fresh water law
On 26 and 27 September 2024, Leiden University's Grotius Centre for International Legal Studies hosted the H2OLAW conference entitled 'Law-science interfaces within the law of the sea and fresh water law’. The conference marked the launch of a multi-year research project led by Dr Hilde Woker and Dr…
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New publication on EU law sexual imagery of minors
Carlotta Rigotti and Christina Pasvanti Gkioka from eLaw – Center for Law and Digital Technologies, have published an article titled 'Overlapping Offences, Divergent Logics: Reconciling EU Law on Sexual Imagery of Minors' in the New Journal of European Criminal Law.
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Publication: De Rijmbijbel van Jacob van Maerlant
In this new edition of the Rijmbijbel there are 159 valuable miniatures, combined with commentary by MA-students from Utrecht. Students in Dutch Language at the universities of Antwerp and Leiden have translated the text passages. Various experts, such as Martine Meuwese (UU), tell more about Jacob…
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Björn de Rijk wins SIAM Posterprize
During the last SIAM / Nonlinear Waves and Coherent Structures / conference, PhD student Björn de Rijk, supervised by Prof.Dr. Arjen Doelman and Prof. Dr. Jens Rademacher, received the ‘Posterprijs’. This award is given to the student with the best Poster Presentation..
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Plant Macro-Fossils and Climate Change
This part of the research programme is carried out by Prof. Dr. René Cappers. It focusses on the continuities and changes in the use of plants at Late Neolithic Tell Sabi Abyad, as well as on their implications as proxy evidence for the climate change c. 6200 BC. Parallel to the design of the other…
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Anisotropic Colloids
While colloidal aggregates are often undesirable due to their random shapes, we exploit them as a starting point to synthesize patchy particles.
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Feeding on the fat: how mycobacterial infections disrupt lipid metabolism
How do pathogenic mycobacteria alter lipid metabolism in human cells and patients, and which disrupted pathways could be targeted for new antibiotics?
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Computational modeling of tumor growth and metastasis and the role of the immune system in tumor destruction
In this project, we aim to obtain a quantitative understanding of the role of the immune system in tumor regression, of the role of tumor cell heterogeneity in cancer growth and of tumor cell migration properties.
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Danny Mekić guest columnist for de Volkskrant
De Volkskrant has a guest columnist every month who writes a column for the website on Sundays. eLaw PhD student Danny Mekić was asked by de Volkskrant to be guest columnist for the month of January.
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De groeiende dreiging van ongecontroleerde AI-macht
Reijer Passchier, universitair staatsrecht en hoogleraar digitalisering en de democratische rechtsstaat aan de OU, waarschuwt in HP/De Tijd hoe weinig controle we werkelijk hebben over kunstmatige intelligentie, terwijl machtige bedrijven steeds meer invloed krijgen op onze democratische samenleving…
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Virtual Reality: binnenkort in het onderwijs aan de universiteit Leiden
Virtual Reality komt steeds dichter binnen handbereik van docenten en studenten. Hoe zou Virtual Reality kunnen bijdragen aan de leerervaringen van uw studenten? Vrijdag 19 februari, kwam een groep van ruim twintig docenten en experts af op een bijeenkomst over deze vraag in Studiecentrum Plexus. Met…
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Save the date: Symposium 'De Middeleeuwen als inspiratiebron'
Op donderdagmiddag 15 mei 2025 organiseert Universitaire Bibliotheken Leiden het symposium ‘De Middeleeuwen als inspiratiebron’. Aanleiding voor dit symposium is de publicatie van het rijk geïllustreerde publieksboek 'Schatten op schrift, 50 manuscripten uit middeleeuws Europa'.
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Studiemiddag Middeleeuwse Verzamelhandschriften uit de Nederlanden (UU, 2 oktober)
Op 2 oktober 2023 zullen meerdere nieuwe delen in de reeks Middeleeuwse Verzamelhandschriften uit de Nederlanden worden gepresenteerd, ditmaal uitsluitend in digitale vorm.
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In hoeverre kunnen de coalitiepartijen de Grondwet nog waarborgen na Wilders uitlatingen op X?
Na de 7 oktober demonstraties schoffeerde Wilders burgemeester Halsema, door op X te roepen dat zij het land moet verlaten. Volgens experts overtreedt Wilders hiermee de gemaakte afspraken met de coalitiepartijen. Wim Voermans, hoogleraar Staatsrecht, hierover aan het woord in het Parool.
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Conferencia Spinoza a cargo de la poeta nicaragüense, Gioconda Belli
Nos complace abrir el X Congreso Internacional, Transhispanismos: contactos y contagios, con la Conferencia Spinoza a cargo de la poeta nicaragüense, Gioconda Belli. Para asistir a la conferencia es importante registrarse. Lo pueden hacer en el siguiente enlace:
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From hunter-gathering to food production
Isotopic insights on human diet from the later stone age to Neolithic in Northwest Africa, Morocco
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Children’s Rights Monitor 2013
The Children’s Rights Monitor provides a thematic overview of the implementation of the UN Convention on the Rights of the Child in the Netherlands.
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Semisynthetic glycopeptide antibiotics
Vancomycin is a last-resort antibiotic for the treatment of many Gram-positive bacterial infections, while remaining inactive against Gram-negative strains.
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Computational speedups and learning separations in quantum machine learning
This thesis investigates the contribution of quantum computers to machine learning, a field called Quantum Machine Learning. Quantum Machine Learning promises innovative perspectives and methods for solving complex problems in machine learning, leveraging the unique capabilities of quantum computers…
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The Indian Frontier: Horse and Warband in the Making of Empires
This omnibus brings together some old and some recent works by Jos Gommans on the warhorse and its impact on medieval and early modern state-formation in South Asia.
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The High Representative in Bosnia-Herzegovina: The Unusual Institutional Arrangement of a Non-Authoritarian, Yet Controlled, Democracy
In this article, Gerrit Dijkstra and Jos Raadschelders from the Institute of Public Administration, argue that Bosnia-Herzegovina survives so far on the basis of negative legitimacy.
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Caught off guard? Evaluating how external experts in Germany warned about Russia’s war on Ukraine
This article reviews how external expertise supports intelligence production and crisis decision-making with Germany's response to the Russio-Ukrainian war.
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Visual Relation extraction Based on Deep Cross-media Transfer Network
Building a Deep Cross-media Transfer Network to extract visual relations that relieve the problem of insufficient training data for visual tasks.
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From molecules to monitoring: Integrating genetic tools into freshwater quality assessments
Freshwater is an important resource, but at a great risk of species decline due to habitat loss, pollution and over-exploitation, and invasive alien species.
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Protecting Democracy in Europe: Pluralism, Autocracy and the Future of the EU
The future of Europe as a community of democratic states is deeply uncertain. The European Union, founded to promote ‘ever closer’ integration, aims nominally for peaceful, prosperous cooperation. But this ideal has been battered by a series of bruising crises, and now by war.
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Prosody in whispered speech: retrieving alternative cues to pitch
The goal of this study is to systematically investigate how intonation (speech melody) is conveyed in whispered speech.
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The Role of Historical Narratives in Extremist Propaganda
In this paper for Defence Strategic Communications, Alastair Reed and Jennifer Dowling seek to show the importance of historical narratives to propaganda by identifying and exploring five ways in which such narratives are exploited to reinforce the extremists' 'competitive system of meaning'.
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Children's Rights Monitor 2015
The Children’s Rights Monitor provides a thematic overview of the implementation of the UN Convention on the Rights of the Child in the Netherlands.
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Unlocking Cosmic Depth and Detail
This thesis utilises the exceptional sensitivity and resolution of LOFAR to explore the low-frequency Universe, while simultaneously advancing the telescope's capabilities to enable new scientific discovery.
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From every angle: novel insights into CC chemokine receptor 2 pharmacology
The CC chemokine receptor 2 (CCR2), a member of the G protein-coupled receptor (GPCR) superfamily, is widely involved in autoimmune and inflammatory diseases. However, no drugs for this receptor have made it to the pharmaceutical market yet.
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Plasmonic enhancement of single-molecule fluorescence under one- and two-photon excitation
This thesis aims to improve the detection from ultra-weak single emitter by enhancing their emission properties with plasmonic nanostructures. We exploit the wet-chemically synthesized single crystalline gold nanorods (GNRs) as our basic frameworks in the whole studies, simply because of their unique…
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Synthetic carbohydrate ligands for immune receptors
One of the main challenges in the development of an effective anti-cancer vaccine is the generation of an adequate and directed cellular immune response.
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Glycosyl Cations in Glycosylation Reactions
This thesis describes the use of a combined approach of computational and experimental techniques to gain novel insights to understand the glycosylation reaction and its reactive intermediates.
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Resistance to PARP inhibition by DNA damage response alterations in BRCA1/2-deficient tumors
Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.
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Improved hard real-time scheduling and transformations for embedded Streaming Applications
This thesis addresses the problem of designing performance and energy efficient embedded streaming systems, that is, systems which process a stream of input data coming from the environment and generate a stream of output data going into the environment.
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Reconstruction and Computational Modelling for Inherited Metabolic Diseases
Accelerating the diagnosis and personalising the management of inherited metabolic diseases.
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Algorithms for analyzing and mining real-world graphs
Promotor: Prof.dr. J.N. Kok, Co-Promotor: W.A. Kosters
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Genomics applications of nanopore long-read sequencing for small to large sized genomes
In this thesis I highlight the applications of Oxford Nanopore Technologies (ONT) sequencing. This technique is a relatively new approach in the sequencing field, where nanopores are embedded in a membrane, DNA molecules are pulled through nanopores and an electrical current serving as the sequencing…
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Sociabilidade do Brasil Neerlandês (1630 - 1654)
Painstaking research in Dutch and Portuguese archive materials, so far poorly assessed on the topic of social relations, reveals intense and intricate associations between different European individuals both in terms of ethnicity and social strata.
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(Inter)national Tax Planning and Policy
Tax scandals, like the Panama Papers, the Paradise Papers, and the Pandora Papers, have made taxation a major topic of public debate. Learn more about this in the new minor Tax and Society: Building a Sustainable and Fair Tax System.
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Medicinal Chemistry
The mission in this division, headed by Laura Heitman, is to design and synthesize novel and better ligands for drug targets. Drug discovery is a lengthy but inspiring adventure. It is often an interplay between academic institutes and pharmaceutical industry, in which scientists at university develop…
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Rebel Legal Order, Governance and Legitimacy: Examining the Islamic State and the Taliban Insurgency
This article explores how ISIS and the Taliban have fostered support through their parallel legal systems.
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Dynamics and radiation from tidal disruption events
When a star gets too close to a supermassive black hole, it is torn apart by strong tidal forces in a tidal disruption event (TDE).
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Nanoparticle – redox protein biohybrids
Artificial photosynthesis aims to produce fuels from solar energy using chemical processes. In semi-artificial photosynthesis, a hybrid approach is taken using both chemical and biotechnology approaches. We aim to develop hybrid systems between light-harvesting nanoparticles and redox-enzymes (oxidoreductases)…