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PhD defence

PhD defence

PhD defence

How does an embryonic stem cell decide if it becomes a heart cell or a kidney cell? That’s the question computational biologist Maria Mircea studied for her PhD research. She looked at the inside of individual cells to analyse how they change. This is what she discovered.

Stack two layers of graphene, twisted at slightly different angles to each other, and the material spontaneously becomes a superconductor. Science still can't explain how something so magical can happen, but physicists use special equipment to reveal what is taking place under the surface.

Heritage Quest is a large-scale citizen science project in the field of archaeology that allows anyone to contribute to scientific research. It is the first large-scale archaeological citizen science project in The Netherlands and one of the few of its kind in the world. As part of the Cultural Heritage…

When putting together your assessment, it may be useful to use an assessment matrix. This is a table in which you link the learning objectives to test questions and indicate the weight you give each objective in the assessment. It can be requested in the context of a programme accreditation.

Identifying novel antibiotic compounds to tackle antibiotic-resistant bacteria. Researchers from Leiden University and VU Amsterdam will unite through a project now funded by NWO’s Open Technology Programme (OTP), which awarded the collaboration nearly one million euros.

Gelderland Heritage and Leiden University’s Faculty of Archaeology have won the European Heritage Award / Europa Nostra Award 2022 in the ‘research’ category with the Heritage Quest citizen science project. ‘Heritage Quest has shown that citizens can play an active role in protecting cultural heritage…

Due to its success, the Leiden2022 Q&A has been extended and is looking for even more thought-provoking, interesting or unusual questions.

The LUMC has become the first institution in the Netherlands to treat a patient with an autoimmune disease using CAR T-cell therapy.

Hosts and creators of the Nebula tv series ‘Archeology Quest’ Lorraine Boissoneault and Stephanie Sammann compete to see if they could have survived during the Palaeolithic, and this time Dr. Andrew Sorensen is there to help. Every episode different archaeological experts are there to teach them the…

The Leiden University Medical Center (LUMC), the Danstem Institute from the University of Copenhagen and the Murdoch Children’s Research Institute in Melbourne have received 300m euros from the Novo Nordisk foundation. The aim of this new international consortium is to bring stem-cell based therapies…

To look for atmospheres around planets outside our solar system is to look for extraterrestrial life. Astronomist Sebastian Zieba used data from the James Webb Space Telescope to study small rocky exoplanets but found no aliens yet. However, his findings are still very interesting for future observations.…

Research

A tenacious postdoc researcher persuaded Professor Marc Koper to research the oxygen reduction reaction. In Koper's eyes, there was little of interest there. But they promptly discovered a whole new way to improve fuel cells on hydrogen and oxygen. Their article appeared in Nature Catalysis on 07 Ju…

PhD defence

Researchers from the Netherlands Cancer Institute, the Leiden University Medical Center (LUMC) and Oncode have created a tracking system that can reveal how often cells have divided. This allowed them to find a yet undiscovered population of immune cells: young memory cells that behave like stem cells.…

‘Rudy van Vliet is always willing to go that extra mile to help us,’ is what students say about him. The lecturer in the Computer Science bachelor’s programme not only teaches his regular courses but also offers additional classes to prepare students for programming competitions. His dedication to students…

What do people wonder about on social media? University lecturer Matthijs Westera is the recipient of an NWO grant to investigate what people are curious about online.

Mechanics play a larger role in blood vessel formation, and other developmental biology, than previously thought. Cells appear to respond to mechanical signals, such as pressure. Through the extracellular matrix, a network of fibrous proteins, cells can supposedly exchange those mechanical signals over…

A bacterium hiding from the immune system and picking up bits of DNA from its environment. The result: gaining new traits, such as better protection against antibiotics. Fortunately, we have not found such a damning scenario yet. However, PhD student Renée Kapteijn did find the first clues, which…

Ilze Bot wants to reduce the prevalence of cardiovascular diseases. Her research focuses on mast cells, which protect us from infections but can also make us ill.

Luca Giomi has the first results of his ERC consolidator grant. He discovered that epithelial cells move collectively but in different ways, depending on the scale you look at. It is hexatic at small scales, and becomes nematic at larger scales: it is a multiscale order. This collective movement of…

Researchers at the Leiden University Medical Centre (LUMC) have managed to culture human heart muscle cells on a massive scale. This is an exceptional achievement because it is very difficult to replicate heart muscle cells outside the body. Using a special technique, the researchers have now created…

During illness, the stiffness or viscosity of cells can change. Tom Evers demonstrated this by measuring such properties of human immune cells for the first time. ‘The stiffness of certain cells could be a way to make a diagnosis,’ Evers said. He defended his thesis on March 26th.

Researchers and clinicians at Leiden University Medical Centre (LUMC) are about to begin a milestone clinical study. It will be the first time a stem cell gene therapy developed in the Netherlands is used in a clinic. The therapy will be used to treat children with SCID, a rare disorder where children…

Bacteria temporarily live without their cell wall if dangerous viruses are near. A remarkable feature, as the cell wall is a sturdy barrier against threats. Still, the discovery has a logical explanation ánd might be of a consequence for fighting pathogenic bacteria, according to Véronique Ongenae,…

Researchers from the Leiden University Medical Center (LUMC) have successfully used stem cell gene therapy to treat a baby with the severe congenital immune disorder SCID. An important milestone: it is the first time stem cell gene therapy of Dutch origin has been administered to a patient, and also…

A COVID-19 vaccine that specifically instructs the immune system to produce T-cells rather than antibodies is shown to provide good protection in a mouse model, Leiden University Medical Center (LUMC) researchers report in Nature Communications. According to them, the alternative vaccine may offer a…

Cells in our bodies are often threatened by errors in our own proteins. The FLOW consortium, comprising scientists from various institutions including Leiden, is poised to meticulously map out for the first time how cells control proteins, correcting or removing faulty ones. This endeavour holds promise…

What’s really happening in the space between the cells in your body? With the Collagen Canvas project, students from Leiden University invite you to explore this question by blending science with art. This interactive artwork immerses you in the dynamics of the extracellular matrix—the invisible structure…