IoT technology poses serval opportunities to supply chains. This thesis employs grey correlation and forecasting models, system dynamics, agent-based modeling, and ex-ante LCA to investigate and quantify the opportunities and risks of IoT-enabled sustainable supply chain operations from both industrial…

Decarbonizing the building stock is critical for realizing the climate-neutral target for the Netherlands.

PhD defence

How can the Safe and Sustainable by Design (SSbD) framework developed in the SSbD4CheM project facilitate the creation of safer and more sustainable chemicals and materials across various industries?

The research within the Food research programme at CML focuses on a transition towards sustainable food production and consumption systems. We investigate from a very small to a very large scale, at a local, national or international level. We do so by researching for example molecular tools, food systems,…

Research at the Catalysis and Surface Chemistry group is comprised of the following research themes:

Twenty years from now, the world population is estimated to be around 8.7 billion people, compared to the current 7.3 billion. In combination with the improvements in living standards and the corresponding growth in consumption, this will result in an enormous increase in the demand for food, consumables,…

All PhD candidates who started their project in 2019 or later take a mandatory course on academic integrity, preferably in their first year.

The power of personalized nutrition lies in being able to conduct clinical research on healthy people while capturing metabolic markers sensitive to the impact of environmental and metabolic stressors (e.g. diet, changing sex hormones and the menstrual cycle).

Promotor: G.J. Kramer Co-Promotor: E.G.M. Kleijn

Promotor: E. Bouwman, Co-Promotor: S. Bonnet

Overall dispersion in LCA as result of inherent uncertainties, spread and unrepresentativeness.

Can Cyanobacteria be engineered to convert the greenhouse gas carbon dioxide into the valuable chemical isoprene?

Circular economy… is it another a buzz word or a concept worth learning more about?

Promotor: S.M. Verduyn Lunel

What are the possibilities of converting biowaste streams into value added products? What current and future technologies will enable this transition with minimal environmental and economic costs? The researchers in H2 steel project will enable the transition of sewage sludge into green hydrogen, steel…

ADHD & ME aims to explore how enhancing self-esteem can break the relation between ADHD symptoms and comorbid disorders, such as anxiety and depression. In this study we assess the effectiveness of a Cognitive Behavioural Therapy (CBT) program called Competitive Memory Training (COMET) for improving…

The Automated Design and Analysis of Algorithms (ADA) research group pursues the development of Artificial Intelligence techniques that complement, rather than replace, human intelligence.

In this thesis we examine certain phenomena in symplectic topology which are related to the theory of isolated singularities.

Statistical distributions in LCA and converting between different representations of these distributions.

The goal of hit discovery is to identify suitable chemical starting points to modulate a drug target. A hit can be, a.o., a small molecule, a protein or mRNA. Hit identification is performed via rational design, genome mining, (targeted) library screening, or in silico approaches.

How can we organise society so as to keep our planet habitable for us and for all other life forms around us? To answer this question, Leiden researchers collaborate across disciplines, from biology to data science, and from environmental economy to archaeology.

IDREEM (Increasing Industrial Resource Efficiency in European Mariculture) is a European research project launched in 2012 to protect the long-term sustainability of European aquaculture. This project has recently been featured on Euronews TV

We study cell-fate decision-making using embryonic stem cells as a model system. Stem cells integrate a large number of cues to direct their development into a great variety of cell types.

Bacteria are highly complex and diverse organisms that have adapted to survive in ecological niches ranging from the most extreme to the most heterogeneous environments.

The Science Council is an advisory committee to the Board of the Institute and consists of the full professors of the Institute.

This dissertation focused on computational methods based on first principles calculations using the Density Functional Theory (DFT) framework. Emphasis was laid on affordable methods that can provide a tradeoff between computational expense and accuracy.

Damien Van Puyvelde and Paul Oling explore how government intelligence agencies can effectively collaborate with the private technology sector to meet their evolving technological needs, focusing particularly on emerging technologies such as artificial intelligence (AI) and quantum computing.

Welcome to StatiCS: the Statistical Consultation Service. The goal of the service is to provide statistical support to PhD candidates and other researchers.

Adhyāyas 96 – 112. The Varāha Cycle and the Andhaka Cycle Continued

PhD defence

Looking for ways to travel more sustainably once you've reached your destination? Here, we offer some ideas and helpful links to guide you in becoming a more responsible tourist. Ecotourism, defined as "responsible travel to natural areas that conserves the environment, sustains the well-being of…

The Chemical Probe Facility is part of the Leiden Early Drug Discovery & Development (LED3) center. Activity-based protein profiling (ABPP) is one of the pillars of chemical biology. ABPP determines the activity of entire protein families in living cells and tissues under physiological conditions, such…

Adoptees in the Netherlands generally do not use more medication than their non-adopted peers.

To get a feeling of how we operate at LED3 when it comes to Early Drug Discovery, please browse through our case studies. When you select a case study you’ll find relevant contacts.

Twenty years from now, the world population is estimated to be around 9 billion people (now 8 billion). In combination with the improvements in living standards and the corresponding growth in consumption, this population will result in an enormous increase in the demand for food, consumables, water…

Urban, Food, Water, Biodiversity, Resources and Energy: these are the main research topics of the Institute of Environmental Sciences. We always strive to be a global leader in our field. And make a real impact with both our research programmes.

This dissertation revolves around the design and implementation of novel instrumentation and related measurement techniques, at the single molecule level, for use in biophysical research. Chapter 1 presents an introduction to the field of fluorescence-based single molecule measurements. In particular,…

Changing burial rites in Early Medieval Northern Gaul, 450-600 CE