High-throughput holistic preclinical screens are increasingly used in drug discovery, to assess both drug efficacy and drug safety.

Van Steenis, Einsteinweg 2, 2333 CC, Leiden

The Joan van der Waals colloquium is an ongoing bi-weekly lecture series.

On 29 November 2018, Roberto van den Heuvel zijn defended his thesis 'Duidelijkheid van fiscale wetgeving'. The doctoral research was supervised by prof. dr. A.O. Lubbers en prof. dr. H. Vording.

Building a Deep Cross-media Transfer Network to extract visual relations that relieve the problem of insufficient training data for visual tasks.

This dissertation is concerned with the development of grammar. Starting from a usage-based perspective, which holds that children use domain-general learning mechanisms to acquire the grammatical patterns of their mother tongue, Beekhuizen shows how to operationalize various concepts from this tradition…

uman skin equivalents (HSEs) are in vitro 3D-skin models that mimic many aspects of the native human skin (NHS) and can be a valuable tool.

Can a newly developed, app-based, personalized maintenance program enhance the effectiveness of the exposure-based one-session-treatment for children with a specific phobia?

In design optimization problems, engineers typically handcraft design representations based on personal expertise, which leaves a fingerprint of the user experience in the optimization data. Thus, learning this notion of experience as transferrable design features has potential to improve the performance…

Hydrogen peroxide (H2O2) is an important bulk chemical that is used in various industrial processes. More than 95% of the H2O2 used in industry is made via the anthraquinone process during which a large amount of energy is going to waste.

Promotor: H.S. Overkleeft, Co-Promotor: B.I. Florea

In this dissertation, we study partition-based models that can be used both for interpretable predictive modeling and for understanding data via interpretable patterns.

Willem Peene defended his thesis on 12 January 2017

Analysis of drug adversity

With the emergence of online social networks (OSNs), the way people create and share information has changed, which becomes faster and broader than traditional social media.

Op zaterdag 3 juni vindt de Museumnacht Leiden plaats. Ook dit jaar zijn Leidse wetenschappers en studenten onderdeel van de programmering.

Een demonstratie in de Utrechtse gemeenteraad zorgde onlangs voor veel opschudding en leidde tot een aangifte. Volgens Rowie Stolk, universitair docent Staats- en bestuursrecht, ‘is het juist de bedoeling van zo’n demonstratie dat het ophef veroorzaakt en een beetje wringt’. Dit leidt er vaak toe dat…

‘Vrijwel elke kritische reflectie op AI en de richting waarin AI zich op dit moment ontwikkelt, ontbreekt’, zegt Reijer Passchier, hoogleraar digitalisering en de democratische rechtsstaat aan de OU en universitair docent staatsrecht in Leiden, in een opiniestuk in de Volkskrant.

Het schilderij van Rein Dool waarop voormalig bestuurders van de Universiteit Leiden zijn afgebeeld, is verhuisd naar de Receptieruimte van het Academiegebouw.

What is students’ engagement in problem-based learning (PBL) and case-based learning (CBL) in teacher certification programs?

The surface and the edges of graphene are expected to provide higher sensitivity and specificity in detecting and characterizing single molecules. However fundamental physical limits exist in reaching an ultimate precision in detecting the dynamics of chemical and biological systems. The research in…

Green infrastrucuture (GI) like urban farm and green roofs could provide many beneficial functions in cities. These include for example food production, flood prevention or increasing biodiversity. MultiGreen project aims at developing an integrated modelling tool to support…

This doctoral thesis is an effort to understand how lipid phase-separation induced by diacylglycerol analogues in lipid-based nanoparticles affects their in vivo behavior, leading to specific nanoparticle-protein communications and selective cell targeting.

Anna van Buerenplein, Anna van Buerenplein 301, 2595 DG, The Hague

Anna van Buerenplein, Anna van Buerenplein 301, 2595 DG, The Hague

We investigate the physics and design of mechanical metamaterial, intricately sculpted materials with properties set by their architecture.

The focus of our theoretical research is understanding the behaviour of soft condensed matter, physical matter which is deformed or structurally altered by thermal fluctuations or small stresses.

Anna van Buerenplein, Anna van Buerenplein 301, 2595 DG, The Hague

Van Steenis, Einsteinweg 2, 2333 CC, Leiden

Van Steenis, Einsteinweg 2, 2333 CC, Leiden

On the occasion of prof Paul van der Heijden’s stepping down as Rector Magnificus and President of the Executive Board of Leiden University in 2013 the Chair bearing his name on Social Justice was established. It was a “farewell present” of the Leiden University to it’s Rector.

The development of new environmentally sound technologies is seen as a key route towards achieving sustainability.

On the 26th of September, Cosmas Rai Amenorvi successfully defended a doctoral thesis. Leiden University Centre for Linguistics congratulates Cosmas on this achievement!

Metabolomics is a powerful tool that can provide a comprehensive insight into the complexity of human biology and the pathophysiology of diseases. By analyzing the metabolome, which refers to the complete set of small (endogenous) molecules (with a mass <1500 Da) present within a given biological system,…

Barrie Sander identifies different categories of risks and concern of relying on artificial intelligence technologies to confront climate change.

On 26 February 2020, Hans-Jan van Kralingen defended his thesis 'De ondeelbaarheid van het pand- en hypotheekrecht, deconstructie van een leerstuk'. The doctoral research was supervised by Prof.mr. W.J. Zwalve and Prof.mr. E. Koops.

Chromatin is an ubiquitous protein-DNA complex that forms the structural basis of DNA condensation in all eukaryotic organisms.

Discover the new MSc in Public Sector Economics at Leiden University, offered entirely in Dutch. This program prepares future policy economists by bridging economic theory, Dutch institutions, and real-world policy challenges. Starting September 2025 in The Hague, it focuses on key issues like inequality,…

Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)

Glycoconjugate vaccines are composed of microbial poly- or oligosaccharides covalently linked to a carrier protein.

A P300-based Brain Computer Interface character speller, also known as P300 speller, has been an important communication pathway, under extensive research, for people who lose motor ability, such as patients with Amyotrophic Lateral Sclerosis or spinal-cord injury because a P300 speller allows human-beings…

The polypept(o)ide hybrid material attracted more and more attention over the past decade by combining the multifunctional characteristics of polypeptides with the shielding characteristics of polypeptoid-pSar possessing similar properties as a shielding material as polvethylene glycol(PEG). Polysarcosine…

Promotor: B. van de Water

Political scientists Huib Pellikaan and Niels van Willigen (Leiden University) use and elaborate on the theoretical insights from game theory in order to understand nuclear security in changing environment. Now that the relations between the US and Russia have deteriorated and smaller nuclear states…

Political scientists Marijn Nagtzaam (Leiden University) and Patrick van Erkel (University of Antwerp) investigate how electoral rules affect intra party preference voting. Focusing on the effect of two specific rules—the option to cast a list vote and on a single versus multiple preference vote—and…