Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.

Sepsis is a life-threatening condition caused by a dysregulated host response to infection, it is associated with significant morbidity, mortality, and with a high financial burden on global healthcare systems. Bacterial infections are the primary cause of sepsis, but the growing prevalence of antimicrobial…

The aim of the RAISE study is to investigate how resilient people respond to stress. Specifically, we will study how key biological systems (HPA-axis, immune system) interact with the brain and social environment in order to facilitate resilient functioning after childhood adversities.

The investigation into the bidirectional communication between the gut and its host is a rapidly growing area of research, attracting considerable attention for its potential to provide crucial insights into health and disease.

Leiden University seeks to bring knowledge, academic top talents, and resources from Leiden and Latin America and the Caribbean together in mutually beneficial joint research projects that are content-driven, based on existing excellent research. Connecting research and researchers.

This thesis describes the development of improved formulations and alternative delivery strategies for polio vaccination.

We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.

This dissertation explores new chemical strategies for the synthesis of self-adjuvanting peptide conjugates and immunomodulatory ligands aimed at targeted activation of the immune system.

De incubatietijd (van infectie tot de eerste symptomen) en latente periode (van infectie tot de start van besmettelijkheid) zijn cruciaal voor het informeren van controle maatregelen aan het begin van een infectieziektenuitbraak. Een voorbeeld is de duur van quarantaine voor potentieel geïnfecteerden,…

Promotor: Prof.dr. J. Kuiper, Co-promotor: Saskia C.A. de Jager

Can the venom of snakes, scorpions and other animals be sources of new antibiotics?

Animal Sciences’ contributions to the Development & Disease research theme include the mechanisms and evolution of embryonic development, the development of cognitive mechanisms, and animal models for understanding mechanisms of human disease.

How interest groups, differences in policy issues and institutional differences between countries affect whether public opinion is translated into policy?

Lecture

On Thursday 8 June 2017 Melanie Fink, Postdoctoral Researcher at the Europa Institute, participated in the Legal Seminar ‘EU Law and Undocumented Migrants: Defending Rights in the Context of Detention & Deportation’.

Between 18 and 20 October, CEPS (Centre for European Policy Studies) and the Migration Policy Centre of the European University Institute organized the ASILE training school for PhD researchers. The training focused on the concepts of responsibility attribution and accountability for fundamental rights…

Christian Lequesne introduces the upcoming special issue on Ministries of Foreign Affairs in this blog post.

In recent weeks, Luuk van Middelaar has commented widely in the European press on the EU response to the corona crisis.

The ongoing coronavirus crisis means that Leiden Law Exchange (LLX) events have now also moved online. On 26 January 2021 policy workers, academics and professionals met in an informal setting under the Chatham House Rule to discuss the recent accusations aimed at the European Border and Coast Guard…

PhD defence

PhD defence

There are many complex links in the chain that provides patients with new drugs: from fundamental science, to clinical tests, to production. The entire chain can be found in Leiden. Leiden University, the Leiden University Medical Center (LUMC) and the businesses at the Leiden Bio Science Park (LBSP)…

Supervisor: Andrea Martella

The soil ecosystem consists of the largest reservoir of biodiversity on Earth.

The Cardiovascular Pharmacology research group headed by Ilze Bot aims to elucidate the mechanisms that underlie atherosclerotic plaque destabilization, which is the key process that leads to acute cardiovascular syndromes such as a myocardial infarction or stroke.

A balanced diet and enough sleep and exercise will help strengthen your immune system.

The Leiden Institute of Chemistry (LIC) is the basis for research and collaborations of the Leiden chemistry groups. Chemistry is the central science enabling a healthy future in a sustainable society. Chemistry researchers at Leiden University take a fundamental approach in finding tailored solutions…

For effective cancer immunotherapy by vaccination, co-delivery of tumour antigens and adjuvants to dendritic cells and subsequent activation of antigen-specific cytotoxic T cells (CTLs) is crucial. In this study, a synthetic long peptide (SLP) harbouring the model CTL epitope SIINFEKL was encapsulated…

Nanodiscs are small, disc-shaped structures designed to mimic biological cell membranes, composed of a lipid bilayer stabilized by scaffold proteins. Membrane proteins play crucial roles in essential processes such as nutrient and waste transport, molecular recognition, and cell signalling, making them…