Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.

Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska

This dissertation combines the use of defined microenvironments, high-resolution fluorescence microscopy, and time-resolved analysis, to study intracellular and cellular motility.

Promotor: T. Schmidt, Co-Promotor: B.E. Snaar-Jagalska

This thesis tackles the difficulty of predicting the liver’s clinical response to novel therapies, a challenge arising from interspecies differences and limitations of existing in vitro models.

Susanna Lindberg(ed.), Artemy Magun (ed.), Marita Tatari (ed.) With this book, we would like to resume the passionate conversation that Jean-Luc Nancy was engaged in throughout his life, with philosophers and artists from all over the world. Now that he has passed away, it is not enough for us to…

The Hazelhoff Centre for Financial Law team regularly publishes in both Dutch and international academic journals and book series.

Prostate cancer (PCa) is one of the most prevalent cancer in males.

Promotor: J.A. Bouwstra Co-promotor: A. El Ghalbzouri

G protein-coupled receptors (GPCRs), one of the largest families of membrane proteins, are responsive to a diverse set of physiological endogenous ligands including hormones and neurotransmitters.

PhD defence

PhD defence

PhD defence

Microbial rhodopsins are photosensitive pigments implemented in the growth and adaptation of a large population of microorganisms.

In this research project, we aimed to obtain more insight in the role of mast cells in the immune driven disorders rheumatoid arthritis and atherosclerosis.

Enabling volume-restricted metabolomics using next-generation microscale analytical tools.

Can Cyanobacteria be engineered to convert the greenhouse gas carbon dioxide into the valuable chemical isoprene?

Indigenous Pasts and the Roman Present

Plants, algae and cyanobacteria have the amazing capacity to perform delicate photophysical and photochemical processes of light capture, excitation transfer, charge separation and catalysis in fluctuating living environments. As a consequence, photosynthetic proteins and membranes form dynamic architectures.…

Below you will find a collection of books, other than those in the BLRN book series, to which members of BLRN have contributed.

PhD defence

PhD defence

The group of Dr. Roxanne Kieltyka designs and synthesizes molecules that self-assemble into polymeric materials using specific non-covalent interactions. These substrates can be used for numerous applications in medicine ranging from disease detection to cell delivery depending on the (bio)molecular…

The Immune Activation and Tolerance group is headed by Dr. Bram Slütter. Vaccination is an experimental, but promising, treatment strategy for atherosclerosis. Previous work has shown that immunization of mice with modified LDL particles can reduce atherosclerotic lesion development, however such vaccines…

Op zaterdag 27 februari organiseert Stichting Zenobia het Vijftiende Zenobiacongres, met de titel Van de Levant tot de Lagune: Venetië en het Oosten. Het congres zal online plaatsvinden en is vrij toegankelijk.

Het project heeft plaats gevonden onder begeleiding van Prof.dr.ir.Tjerk Oosterkamp. De titel van de presentatie is:

Op vrijdag 4 april 2025 organiseert de werkgroep Stedengeschiedenis een bijeenkomst bij de Rijksdienst voor het Cultureel Erfgoed onder de titel ‘Archeologie en de stad’. De studiedag is gratis en voor iedereen toegankelijk.

Het project heeft plaats gevonden in de Gorter LUMC groep onder begeleiding van Dr. J.W.M. Beenakker en prof.dr.ir. T.H. Oosterkamp . De titel van de presentatie is:

Het project heeft plaats gevonden in de KM3NeT Nikhef Amsterdam groep onder begeleiding van Dr. D.F.E. Samtleben en Prof.dr.ir. T.H. Oosterkamp. De titel van de presentatie is:

Het project heeft plaats gevonden in de QMO groep onder begeleiding van Dr. Michiel de Dood en Dr.ir. Sense Jan van der Molen. De titel van de presentatie is:

Leiden chemist Roxanne Kieltyka is part of the 2018 Talented 12 list of the American Chemical Society. That was announced by the journal Chemical & Engineering News on 19 August.

Op donderdag 17 april 2025 neemt prof. dr. Marco Mostert, Hoogleraar Middeleeuwse Geschiedenis aan de Universiteit Utrecht afscheid.

15 March 1979 - 11 October 2024

Tussen 14 en 30 september 2022 wordt Het Land van Belofte gespeeld door Theatergroep De Kale. Het Land van Belofte neemt u mee naar de groteske verhaalwereld van middeleeuwse pelgrims naar het Heilig Land. Het Land van Belofte is gebaseerd op het zestiende-eeuwse tafelspel Schipper, Pelgrim en Post.…

How have human-environmental entanglements changed in the Gulf of San Miguel, Darien, Panama, from the first traces human practices through to the present?

The last two months of 2016 were a very productive time for the ACPA. We had no less than 6 promotions!

Leiden researchers have developed a groundbreaking model to advance cancer immunotherapy. Using a 3D printer, they create mini-tumors within an environment that closely mimics human tissue. They have also developed a method to monitor real-time interactions of these mini-tumours with immune cells during…

Within the ICM 2018 project, Leiden University cooperated with 25 partner universities from 14 countries. In total, 97 mobilities were granted to this project - 65 mobilities were realised (some mobilities had to be ended prematurely due to covid-19, others were finished online).

With cancer, the immune system is a double-edged sword: it can attack tumour cells, but can also help them grow and spread. It is a question of harnessing it. This is what Professor Karin de Visser argued in her inaugural lecture on 15 November 2019.

On Monday the 8th of December, the annual symposium of the IBL will be organized at the main building of the LUMC Leiden. This year’s theme is “Integrative Biology towards Healthy Communities”.

The Oncode Institute is a new international network organisation that focuses on making sure that new scientific findings on cancer are implemented in patients as rapidly as possible. Two young female researchers at Leiden University have been selected to join Oncode: Laura Heiman (Leiden Academic…

Cryogenic memories, antibiotic treatment for urinary tract infections and recycling plastic sustainably. These are the subjects of the three NWO-XS grants awarded to Leiden Science researchers.

From the 11th of May Ewa Snaar-Jagalska has been appointed Professor in the field of cellular tumor biology within the Faculty of Science at the Institute of Biology Leiden. Her research focuses on the cellular tumor biology and human cancer modeling in zebrafish

As of April 1, 2018, Erik Danen has been appointed as Professor of Cancer drug target discovery at the Leiden Academic Centre for Drug Research (LACDR). His discipline is cell biology of cancer, in which he focuses on the mechanisms underlying metastasis and therapy resistance.

Ewa Snaar-Jagalska, Shuning He and colleagues from IBL, LION and LACDR reported on a new zebrafish study to understand micrometastasis of human cancer cells. They discovered a novel role for neutrophils in assisting metastasis formation, which provides critical insights for anti-cancer therapies.

Zebrafish-human communication shows that cancer cells lacking a signaling protein are less able to develop aggressive metastatic properties. This discovery has been made by molecular cell biologist Claudia Tulotta. PhD defence 14 June.

Op maandag 1 april 2024 stierf onze leermeester, vriend en gewaardeerd collega Dr. Alexander Hendrik de Groot (Sander).

Met groot plezier heeft de Universiteit Leiden van 1 tot 4 november het X Congreso Internacional de la Asociación de Hispanistas del Benelux (AHBx) georganiseerd, met het thema Transhispanismos: contactos y contagios (Transhispanismes: contact en besmetting). De AHBx is een platform in de Benelux dat…

Seven talented female scientists join the fight against cancer of the Oncode Insitute. Laura Heitman of the Leiden Academic Centre for Drug Research is one of the new Junior Investigators. ‘I hope to discover new druggable targets’.

One used 3D cell models to study colorectal cancer, while the other used machine learning for more efficient blood donation. For these achievements, Marieke Vinkenoog and Simon Christian Hansmann were awarded the Krijn Rietveld Memorial Innovation Award on Tuesday 2 September.