370 search results for “t cells” in the Staff website
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Cast #4: Changes to administrative law in the Netherlands with Prof. T. Barkhuysen
Leiden Law Cast is a podcast made by Leiden Law School, Leiden University, for everyone who wants to learn more about current legal issues.
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Jonathan Hak on the paramount importance of the truth – and why we shouldn’t always take images at face value
Hak, lawyer, international imagery law lecturer, and adjunct associate professor, talks about his PhD research on the use of images in international criminal prosecutions. He was a public prosecutor in Canada for over 30 years and dealt primarily with the prosecution of homicides and other major cri…
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Taarique teaches career planning but doesn’t want students to plan their future too strictly: ‘Keep on experimenting’
In the ‘Educatips’ column, psychology lecturers share their most important insights on teaching. This month: Taarique Debidin thinks making contact with one another is more important than cramming knowledge. ‘I’d get no energy at all from being a formal lecturer.’
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In memoriam: Prof. dr. J.T.P. de Bruijn (1931-2023)
On Monday 23 January 2023 J.T.P. (Hans) de Bruijn passed away at the age of 91. Until 1995 he held the Chair of New Persian Language and Culture at Leiden University.
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President of the European Parliament in The Hague: ‘Your friends don’t want to vote? Let me call them’
‘We have to have accountability.’ That was Roberta Metsola’ for her audience on Thursday evening. The President of the European Parliament had come to the Wijnhaven building to speak with students.
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two hundred local chronicle texts launched: A few years ago that wouldn’t have been possible'
Too expensive groceries, diseases suddenly breaking out: from the sixteenth to the nineteenth century, hundreds of people documented the world around them in chronicles. A significant number of these texts have been digitised in recent years. Professor of Early Modern Dutch History and project leader…
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Academic and non-academic staff do an exchange: ‘We don’t know enough about each other’s worlds’
At a work meal HR Policy Adviser Petra Boerlage and Associate Professor Robert Stein got talking about the ‘worlds’ of academic and support staff: are they really that different, they wondered. And wouldn’t it be good if staff knew more about each other? The two put their money where their mouths are…
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Rubicon for research into Roman law: ‘We don’t know what wider society thought about law’
Expert in Classics Renske Janssen has been awarded a Rubicon grant. She will use the grant to conduct research at the University of Edinburgh into how Roman law was perceived by society at the time.
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Report: Tracking down green spaces in The Hague in places you don't always want to be
Although there is considerable evidence that nature in the city is beneficial to both people and animals, we still do not have an overall picture of those benefits. To rectify that, a Leiden PhD candidate and a student – armed with a cargo bike – are using The Hague as a life-size laboratory.
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‘You can’t just go to the field and leave again with data’: meet LUCIR scholar Corinna Jentzsch
Corinna Jentzsch, Assistant Professor of International Relations at the Institute of Political Science and co-convener of the Leiden University Center for International Relations (LUCIR) has conducted extensive fieldwork in Mozambique. Her resulting book, Violent Resistance: Militia Formation and Civil…
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Joey Zuijderveldt won first prize in the ‘Schild-De Groen Onderzoeksprijzen' for cancer research
One of our PhD candidates at the LACDR, Joey Zuijdervelt, recently achieved recognition by winning the first prize in the ‘Schild-De Groen Onderzoeksprijzen’ for cancer research. His award-winning master’s thesis explored glioblastoma multiforme through an innovative orthotopic zebrafish xenograft model,…
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Connected on climate change: "Especially as a researcher, you shouldn't always take the plane to a conference"
On Thursday afternoon, 6 October, Lara Wierenga, Anne Urai and Niels van Doesum kicked off the first edition of Psychology Connected, a recurring event organised by the Science Committee, where big questions and small conversations easily alternate.
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brothers write book about nature and adventure in Eastern Europe: 'I didn't know there live pelicans in Romania'
With a self-converted red camper van, biologists and twin brothers Kevin and Marvin Groen go on a nature adventure in Eastern Europe. Together, they search for wild animals, beautiful nature and places to sport. From a long search for a bear in the Slovakian wilderness to the discovery that pelicans…
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Research finds WiFi isn’t the only thing connecting us during video calls: so are our bodies
Can we truly connect with each other through video calls? Yes, according to a recent study. Psychologists found our bodies synchronise almost as much in digital conversations as in real life. But this doesn’t mean we should skip in-person meetings altogether, says researcher Fabiola Diana.
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1K Z1E J3 bench placed on Wijnhaven Rooftop Garden: ‘Don't be afraid to start a conversation'
‘Een goed gesprek begint met iemand écht zien.’ (A good conversation starts with truly seeing someone). That text is written on a plaque that was screwed onto a IK Z1E J3 (I see you) bench on the Wijnhaven Rooftop Garden on Monday morning. The bench acts as a symbol to create room for discussions about…
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Researchers discover how malaria parasite survives in mosquitoes
Researchers from Leiden University Medical Center (LUMC) have discovered how malaria parasites escape the immune system of mosquitoes. The so-called QC enzyme changes proteins on the outside of the malaria parasite such that the immune cells are unable to recognise the parasite. As a result, the parasite…
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‘Look beyond your own discipline’
Good research means looking beyond disciplinary boundaries, said Professor of Molecular and Cellular Biochemistry Remus Dame in his inaugural lecture on 10 May. Processes that take place on DNA shouldn’t only be researched in a test tube but also in living cells, for instance.
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Why you should publish negative data
As a bachelor student of Bio-Pharmaceutical Sciences, Femke Vlaswinkel wrote a research proposal she was allowed to carry out in her master’s BPS. Femke subsequently graduated with honors. Her research was published in the journal Scientific Reports, she won an award from the Dutch Pharmacy Society…
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Atherosclerosis resembles an autoimmune disease. Marie Depuydt graduated on this topic, with honours
In addition to cholesterol and high blood pressure as risk factors for atherosclerosis, we may need to address our own immune system to prevent a heart attack or stroke. Marie Depuydt revealed which cells exactly reside in the atherosclerotic plaque that narrows an artery. The presence of a diverse…
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Templeton Grant Drukker News
In a project funded by the John Templeton Foundation to the group of Micha Drukker, scientists will produce stem cells from short and long living understudied species to model cellular and organismal lifespan.
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Improving the treatment of pathogenic fungi. ‘The process is working, but not that well…’
Fungi germinating in the lungs of patients. Doesn’t sound too nice, does it? Luckily, humans can deal with this normally, and we are able to clear the infection before anything comes to harm. However, in people with health issues, Aspergillosis can cause a lot of damage, especially if the fungus becomes…
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Leideners and researchers learn from each other at the Science Market
3 October University has become something of a tradition: a bit of science among the Leidens Ontzet celebrations. During the new and improved edition, the WetenschapsWarenMarkt (Science Market), visitors spoke to researchers about the nitrogen problem, making organs and the city’s connections with A…
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Preventing heart attacks by earlier detection of cardiovascular disease
In the Netherlands, 1.55 million people suffer from cardiovascular diseases. Yet, acute cardiovascular events, such as a heart attack or stroke, often occur unexpectedly. That is because many people do not know they are at risk for such an event. Immunological researcher Amanda Foks and her colleagues…
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Publication on the design of multifunctionalized nanoparticles
Despite considerable progress in the design of multifunctionalized nanoparticles (NPs) that selectively target specific cell types, their systemic application often results in unwanted liver accumulation. The exact mechanisms for this general observation are still unclear.
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Modified caffeine molecules help medical research move forward
Before researchers can develop targeted drugs, they need to know exactly how a disease works. Biochemist Bert Beerkens created molecules that allow them to find out. He used caffeine as the basis for new molecules that enable research into certain receptor proteins on cells.
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Marie Depuydt receives presentation award at the 10th EMBRN meeting in Utrecht
From 11-13 July 2022, the 10th EMBRN International Mast Cell and Basophil Meeting took place in the Utrecht University Academia Building in Utrecht. During this meeting, novel insights and developments in the field of mast cell and basophil biology in both health and disease were shared.
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Malformations in heart, eyes and nervous system: Nano-plastics disrupt growth
Nano-plastics cause malformations. Meiru Wang, researcher at the Institute of Biology Leiden, looked at the extreme effects polystyrene nano-particles could have, using chicken embryos as a model. Her results were quite alarming. Especially as nano-particles are everywhere. In the air, floating through…
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Is a cancer pill a matter of time?
A cancer pill, preferably without severe side effects, is something we’d all welcome. Is it a matter of time before such a pill is a reality? We put this question to three Leiden researchers and asked how they themselves are contributing to new cancer treatments.
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Grants to build large-scale research facilities
Five projects with researchers from Leiden University have received a grant from the Dutch Research Council (NWO) to build or upgrade existing research facilities.
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What you see is not what you get: the importance of what you don't see
Cultural anthropologist Sabine Luning, cultural historian Paul van de Laar and professor of architecture and urban development history Carola Hein say that the things that are not shown in images are also worth studying.
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ERC-grant for Sebastian Pomplun to cure disease by controlling gene expression with synthetic transcription factors
Sebastian Pomplun receives an ERC starting grant of 1.85 million Euros in five years. He wants to develop synthetic transcription factors that can enter cells and activate or deactivate specific genes. For example to disrupt cancer-related processes or to trigger the production of an important missing…
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Can Parkinson's be stopped by unravelling protein fibres? Anne Wentink finds out with a Vidi grant from NWO
In brain diseases such as Parkinson's and Alzheimer's, proteins clump together to form fibres. ‘Chaperone proteins’ unravel those fibres, but in the test tube biochemist Anne Wentink saw that this can also cause new problems. She is going to find out what happens inside cells to determine what a drug…
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FCVB moderated poster award for Esmeralda Hemme
During the 2024 Frontiers in CardioVascular Biomedicine (FCVB) conference, which was held from April 12-14 in Amsterdam, Esmeralda Hemme from the BioTherapeutics division received the award for best moderated poster.
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From discovery to business: 'In the lab, we often don't realise that we are working to help an immense number of patients'
'It gave our team a big boost to hear that our work was valuable,' says medical chemist Elmer Maurits about the moment they won the Venture Challenge. With their company Iprotics, they want to develop a drug that can better treat patients with autoimmune diseases and blood cancers. 25,000 euros of prize…
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Vidi grant for seven researchers from Leiden University
From malaria parasites as a vaccine to how top-level bureaucrats reach their decisions: seven researchers from Leiden University have received a Vidi grant from the Dutch Research Council (NWO). This 800,000-euro grant will enable them to develop their own innovative line of research over the next five…
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Iprotics Wins the Venture Challenge Spring 2022
The winner of the 2022 Spring edition of the NWO Venture Challenge was announced during the Dutch Biotech Event. The innovative startup Iprotics has developed specific proteasome inhibitors that potentially treat multiple myeloma (MM) without the side-effects known from traditional proteasome inhibi…
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Call: collaboration between humanities and regenerative medicine
Research
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How a pathogenic bacterium searches for food
Bacteria whirl around in the mouths of most people, forming dental plaques and sometimes causing nasty gum infections. Treponema denticola might be a dangerous pathogen, but not much is known about this bacterium. It was up to Ariane Briegel and her research group to change that.
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Veni grant for ten Leiden researchers
Ten Leiden researchers have been awarded a Veni grant by the Dutch Research Council (NWO). The grant, of up to 280,000 euros, will enable them to elaborate their ideas over a period of three years.
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Superselective bonds light up
Rather than one key and one strong lock, biology often uses tens or hundreds of weaker links to bind parts together, such as cells membranes. This allows for selectivity and also reversibility: the binding can also be undone. Researchers first caught this phenomenon using spheres or colloids, and published…
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700,000 euros for the fight against aggressive breast cancer
To inhibit proteins that contribute to the growth of aggressive cancer cells, that’s the plan of Professor Bob van de Water and his team. They will receive over 700,000 euros from the KWF Dutch Cancer Society for their research. Researcher Maaike Vreeswijk and pathologist Danielle Cohen are affiliated…
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Flu stops when you block the enzyme that cleaves off virus particles
A flu virus could cause a pandemic. And then we would be poorly armed because flu viruses are starting to become resistant to flu medications like Tamiflu. Chemist Merijn Vriends successfully worked on an improved version of such medications. He will be awarded his doctorate on September 12th.
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Can we live longer? Leiden physicist makes discovery in protective layer in genes
With the aid of physics and a minuscule magnet, researchers have discovered a new structure of telomeric DNA. Telomeres are sometimes seen as the key to living longer. They protect genes from damage but get a bit shorter each time a cell divides. If they become too short, the cell dies. The new discovery…
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ERA4Health grants for Bram Slütter, Amanda Foks and Ilze Bot
Recently, Bram Slütter, Amanda Foks and Ilze Bot all individually obtained an ERA4Health research grant from the CARDINNOV 2023 program. In this program, which is co-funded by the EU and in the Netherlands by ZonMW, 17 consortia consisting of 3-5 European academic partners were selected for funding…
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Inaugural lecture prof.dr. B.T. Heijmans
Inaugural lecture
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Developing new therapies to fight muscle disease
Biophysicist Alireza Mashaghi and his collaborators are taking up the fight against muscular dystrophy: genetic disorders that cause muscle weakness. They want to inhibit the clumping of proteins that results in toxic aggregates. For this, the team receives 550,000 euros from Health Holland. The team…
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Targeting the immune system to inhibit atherosclerosis
A new treatment for atherosclerosis showed promising results in isolated cells but proved to be less effective in initial animal tests. Bachelor student Biopharmaceutical Sciences Willemijn van der Heijden aimed to understand why. She investigated whether the formation of a protein layer around the…
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This is how physicists contribute to the energy transition
Studying surfaces of solid materials: it may not seem relevant to energy consumption, but it is. Marcel Rost studies how platinum electrodes wear out. Those electrodes are a crucial component in the fuel cells of hydrogen-powered cars. ‘We need to make the switch from fossil fuel energy to hydrogen.…
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Four Leiden consortia awarded large NWO grants
No less than four Leiden research teams have been awarded a grant by NWO. On 27 July NWO honoured 21 applications in the Open Competition ENW-XL. NWO awards the grants to consortia in the exact and natural sciences who are doing unconnected fundamental research that is 'driven by curiosity'.
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Biological Origami at molecular level: folding a single protein
Human cells are protecting their proteins from unfolding and aggregating. That's what biophysicist Alireza Mashaghi and his team discovered after seven years of in-depth research into the folding mechanisms of proteins. With an unprecedented approach, the team was able to study the folding of a single…