1,002 search results for “that immune responses” in the Public website
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Vidi grant for seven researchers from Leiden University
From malaria parasites as a vaccine to how top-level bureaucrats reach their decisions: seven researchers from Leiden University have received a Vidi grant from the Dutch Research Council (NWO). This 800,000-euro grant will enable them to develop their own innovative line of research over the next five…
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‘Never stop trying’: Barz sees his polymers enter clinical trials
A new class of polymers has been used in patients for the first time. The compound is the first new drug solubilising agent in decades. Introduced in 2014 by chemist Matthias Barz from Leiden University, it offers a unique alternative to current options.
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Vidi grants for nine Leiden researchers
From artificial intelligence to letters from the Dutch East Indies and from breast-cancer gene BRCA-1 to the collaboration between government and opposition: nine researchers from Leiden University have been awarded a Vidi grant for their research.
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Funding for four Leiden studies in the fight against arthritis
Four researchers from Leiden University will receive funding from arthritis foundation ReumaNederland over the next five years. This should facilitate long-term research into arthritis.
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Five ERC Starting Grants for young researchers from Leiden
The ERC has awarded a Starting Grant to five promising researchers from Leiden. Two are from the Faculty of Social and Behavioural Sciences, one is from the Faculty of Humanities/Governance and Global Affairs, one from the LUMC and one from the Faculty of Science.
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Five Leiden contributions to NWO Perspectief projects
Five consortia within the Perspectief programme that include Leiden researchers have received funding to start their research projects. These projects focus on (further) developing technological innovations, with societal and economic impact at their core.
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Melanie Fink on Frontex and Access to Justice
On 6-8 and 10-13 November 2020, the Network for Migration Law (Netzwerk Migrationsrecht) organised their 14th annual conference on the topic of ‘law at the border’.
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Working Paper Series
The Grotius Centre Working Paper Series is an occasional series through which researchers in the Grotius Centre can publish the unedited versions of manuscripts that have been accepted for publication by journals and books.
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Analysing diseases through interactive visual interfaces
Alzheimer’s disease and cancer are two examples of diseases that are related to malfunctioning cellular patterns. The examination of cell tissue, however, takes a lot of time and generates a lot of data. To make the analysis of data easier, Antonios Somarakis of the Data Science Research Programme (DSRP)…
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Prof. Johan Kuiper will retire as of November 1st 2024 after 40 years of research and education
On November 1st, 2024, professor Johan Kuiper will retire and be appointed as emeritus professor at Leiden University. Since November 2008, Johan Kuiper was professor of Therapeutic Immunomodulation in the division of, at that time, Biopharmaceutics (which later on became the division of BioTherapeutics)…
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Sander van Kasteren: from molecule builder to Professor of Chemical Immunology
Sander van Kasteren only noticed some small, subtle changes since he was appointed professor on 1 May. Still, he has to get used to the idea, even though he had been working towards the professorship for a few years. ‘I don't quite see myself as a professor yet.'
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Silver and light: a powerful combination with the potential to save lives
Packages of DNA strands containing silver, measuring just two or three nanometres in size. Leiden physicists Donny de Bruin and Dirk Bouwmeester create these packages, which can enter living cells on their own. They then activate the silver with light, causing the cells to break down. This could, in…
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Grants for fundamental research in Leiden
Three fundamental research projects at Leiden in physics, chemistry and medical science have received funding from the Dutch Research Council (NWO). They involve research on magnetic fields in the universe, the role of myeloid cells in cancer immunotherapy and the evolution of ancient proteins.
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Bacteria under stress can live without cell wall
Thread-like bacteria make cells that no longer have a cell wall under the influence of osmotic stress. A remarkable discovery, since the cell wall serves as a protection barrier for bacteria. It could also help to explain how pathogenic bacteria can hide in our body from our immune system. A team of…
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Preventing heart attacks by earlier detection of cardiovascular disease
In the Netherlands, 1.55 million people suffer from cardiovascular diseases. Yet, acute cardiovascular events, such as a heart attack or stroke, often occur unexpectedly. That is because many people do not know they are at risk for such an event. Immunological researcher Amanda Foks and her colleagues…
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Investigating inflammation: new leads for treating atherosclerosis
How do you detect people at high risk of heart attacks and strokes? And how can we improve the treatment of atherosclerosis? These are the questions that keep LACDR researcher Marie Depuydt busy. She is investigating the immune cells that contribute to the worsening of atherosclerosis. ‘It's a challenging…
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Modified caffeine molecules help medical research move forward
Before researchers can develop targeted drugs, they need to know exactly how a disease works. Biochemist Bert Beerkens created molecules that allow them to find out. He used caffeine as the basis for new molecules that enable research into certain receptor proteins on cells.
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Impurities in sugar excipients could cause drugs to fail
Sugar excipients, needed to stabilize medicines, can be unsafe for patients due to an impurity discovered recently by Daniel Weinbuch. ‘The biopharmaceutical industry should now consider new excipient quality criteria for safer drug development,’ he says. PhD defence on 13 December.
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New insights into mycobacterial infections with NWO grant
Why are mycobacteria such successful pathogens? And are there defence mechanisms in the body that help reduce an infection? To find out, Annemarie Meijer has been awarded the NWO Open Competition ENW-XL grant. She will not explore this quest alone. Five other leading Dutch research groups are participating…
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User-friendly test brings global elimination of leprosy closer
Researchers from the Leiden University Medical Center (LUMC) are working on the first diagnostic test for leprosy that can be used outside a laboratory. This will not only reliably diagnose leprosy, but also be cheap and easy to use. Leprosy mainly occurs in low-income countries. A double challenge…
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Drugs with fewer side effects through a collaboration between LACDR and PTS
LACDR, the Leiden Institute for Drug Research, developed better tolerated excipients to prevent adverse effects related to the surface of nanosized drugs such as vaccines. LADCR professor of Biopharmacy Matthias Barz and Polypeptide Therapeutic Solutions (PTS) are collaborating to develop processes…
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EU awards 18 million euros for research into new antibiotics
An international consortium of research groups is aiming to develop novel antibiotics against the tuberculosis bacteria and two other deadly bacteria. The European Union has awarded a total of 18 million euros to the RespiriTB and RespiriNTM projects. Researchers from the Leiden University Medical Centre…
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Treatment before patients develop rheumatism provides lasting relief
Early treatment benefits patients who have not fully developed rheumatoid arthritis but are in the preliminary stages of the disease. This is what researchers from the Leiden University Medical Centre (LUMC) have reported in The Lancet. Patients in the pre-arthritis stage who were temporarily prescribed…
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Sabine van der Asdonk wins Gratama Science Prize 2021
For her research into complex family problems, an assistant professor in Forensic Family and Youth Care Studies Sabine van der Asdonk has won the Gratama Science Prize 2021, a prize for talented young researchers from the universities of Leiden and Groningen. The jury praised Van der Asdonk’s excellent…
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Four Leiden University researchers receive Rubicon Grants
Four Leiden researchers, who have recently obtained their PhDs, will receive a Rubicon Grant from NWO to conduct research abroad. A total of 22 scientists have received Rubicon Grants. This grant aims to provide young, promising scientists with international research experience.
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Four Vici grants for Leiden University researchers
Four researchers from Leiden University have been awarded prestigious Vici grants the Dutch Research Council (NWO) has announced. The honoured applications are from researchers at the Faculty of Social and Behavioural Sciences, Leiden Observatory, the LUMC and the Faculty of Archaeology.
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Leiden’s poo can help rid patients of resistant gut bacteria
Transferring poo from healthy donors to the intestines of chronically ill people has beneficial effects on these recipients’ gut bacteria, also in the longer term. This is the conclusion of research by the Leiden University Medical Center (LUMC) and the Netherlands Donor Feces Bank (NDFB).
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First clinical trial with genetically modified malaria vaccine completed
In an innovative study, Radboudumc and LUMC jointly tested a candidate vaccine based on a genetically weakened malaria parasite. The results of this clinical trial, published in Science Translational Medicine, show that the vaccine is safe and elicits a defense response against a malaria infection.
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Antibodies against rheumatic diseases tested directly on patients
Leiden Professor of Translational Rheumatology Hans Ulrich Scherer has one foot in the clinic, where he helps patients, and the other in the lab, where he supervises researchers. He bridges these two worlds in his hunt for autoimmune rheumatic diseases.
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Quantum particles and bacteria without cell walls: KLEIN grant for Beenakker and Claessen
Are Weyl particles the ideal conductors? Do cells without a cell wall play a role in chronic Tuberculosis infections? Carlo Beenakker and Dennis Claessen want to answer these questions. They both received a KLEIN grant from the NWO. With these grants, NWO wants to stimulate innovative, fundamental r…
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How drugs work better when encapsulated in nanoparticles
Chemist Tobias Bauer discovered ways to improve drugs by encapsulating them. Packages with iron nanoparticles, for example, can stimulate immune cells. Bauer will receive his PhD on 9 June.
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Virologist Meta Roestenberg and Arabist Petra Sijpesteijn elected as members of KNAW
The Royal Netherlands Academy of Arts and Sciences (KNAW) has elected 16 new members, including two academics from Leiden: internist-infectiologist Meta Roestenberg and Arabist Petra Sijpesteijn.
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eLaw hosted valorization workshop SCALES project
Is the General Data Protection Regulation (GDPR) adequate in ensuring responsible innovation using data analytics? What is the role of ethics with regard to placing limits on technological developments? Does innovation drive business and industry transformations, or does shareholder value maximization…
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Mapping disciplinary differences in Responsible Conduct of Research: A Delphi study
Seminar
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FAIR - From FAIR to FAIR2: Turning principles into practice for responsible, AI-ready data
Webinar with Q&A
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PhD Thesis: Development of human skin equivalents to unravel the impaired skin barrier in atopic dermatitis skin
Recently, the PhD thesis of Lolu Danso Eweje appeared entitled ’Development of human skin equivalents to unravel the impaired skin barrier in atopic dermatitis skin’.
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Discoverer of the Year 2014: Annelien Zweemer
Former PhD student Annelien Zweemer was granted the C.J. Kok Award 2014, also known as “Discoverer of the Year”. A festive ceremony took place at the Faculty’s New Year’s reception on January 6, 2015.
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Portraits Johan Kuiper and Ilze Bot on Hartstichting.nl
The Heart Foundation has portrayed researchers Johan Kuiper and Ilze Bot of the Leiden Academic Centre for Drug Research (LACDR) who fight heart and brain infarcts in the lab.
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Jelle Goemanj.j.goeman@lumc.nl | 071 5269700
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Martine Jagerm.j.jager@lumc.nl | 071 5269111
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Rob Nelissenr.g.h.h.nelissen@lumc.nl | 071 5263606
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Olaf Dekkerso.m.dekkers@lumc.nl | 071 5269111
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Thijs van Oschm.j.p.van_osch@lumc.nl | 071 5269111
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Pieter Hiemstrap.s.hiemstra@lumc.nl | 071 5269111
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Ferry Ossendorpf.a.ossendorp@lumc.nl | 071 5263800
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Gerhard Burgerg.a.burger@lacdr.leidenuniv.nl | 071 5274285
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Saskia le Cessies.le_cessie@lumc.nl | 071 5272124
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Bram Kostera.j.koster@lumc.nl | 071 5269294
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Adam Cohena.f.cohen@lumc.nl | 071 5269111
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Rudolf Poolmanr.w.poolman@lumc.nl | 071 5269111