Could we stop cancer cells by cutting off their energy supply? That’s what Dione Blok, a bachelor’s student in Bio-Pharmaceutical Sciences, aimed to find out during her thesis research. She investigated a compound that affects the tumour cells’ energy metabolism. ‘Hopefully, these insights will provide…

The more data from cancer research we pool, the better we can search for new treatments. But how can we keep patient data safe when sharing it? Leiden researchers will tackle this challenge in a major European project.

How do cells repair their damaged DNA—and what happens when that process is hindered and cancer arises? Sarah Moser has taken a closer look during her PhD, uncovering surprising insights that could help improve future cancer treatments.

This study is important because it seeks to uncover whether clinicians' communication influences neurobiological and physiological outcomes for patients.

One used 3D cell models to study colorectal cancer, while the other used machine learning for more efficient blood donation. For these achievements, Marieke Vinkenoog and Simon Christian Hansmann were awarded the Krijn Rietveld Memorial Innovation Award on Tuesday 2 September.

Sebastian Pomplun from the Leiden Academic Centre for Drug Research has recently received an ERC Proof of Concept grant for his ambitious MYSTIC project. This initiative is set to transform cancer treatment by advancing the development of HeloMYC, a pioneering therapeutic candidate designed to target…

Luca Giomi has the first results of his ERC consolidator grant. He discovered that epithelial cells move collectively but in different ways, depending on the scale you look at. It is hexatic at small scales, and becomes nematic at larger scales: it is a multiscale order. This collective movement of…

When you think of physics, do you think only of complicated formulas? You’re not the only one. Therefore, every year, the Leiden Insitute of Physics organises the LION Image Award to show another side of physics: beautiful images about intriguing science. The winner of the 2022 photo competition captured…

Half of all people with cancer in the Netherlands are aged 70 or older, and as the population continues to age, this number will only rise. Yet vulnerable older people with cancer are often overlooked, says PhD candidate Joosje Baltussen.

On 14 April, the National Growth Fund awarded million euros in grants to two consortia in which Leiden's science faculty is involved. Pharma-NL will receive 80 million euros and Oncode-PACT 325 million euros. Pharma-NL wants to make medicines available to the patient faster and more sustainably. Oncode-PACT…

How can you ensure that more experimental drugs reach the finish line? At the moment, only one in twenty cancer drugs that are tested on humans makes it to the market. This is an enormous loss for patients and society. With a grant from the National Growth Fund, Oncode-PACT aims to efficiently select…

During illness, the stiffness or viscosity of cells can change. Tom Evers demonstrated this by measuring such properties of human immune cells for the first time. ‘The stiffness of certain cells could be a way to make a diagnosis,’ Evers said. He defended his thesis on March 26th.

One of our PhD candidates at the LACDR, Joey Zuijdervelt, recently achieved recognition by winning the first prize in the ‘Schild-De Groen Onderzoeksprijzen’ for cancer research. His award-winning master’s thesis explored glioblastoma multiforme through an innovative orthotopic zebrafish xenograft model,…

Facility

Accelerating the development of new cancer medicines by joining forces—that’s the mission of Oncode Accelerator, a Dutch consortium that recently welcomed three Leiden-based PhD candidates. Under the guidance of Gerard van Westen, Marc Boef, Remco van den Broek, and Lucina-May Nollen are exploring how…

If doctors could better estimate a patient's chances of survival, this would help in choosing a specific treatment. It would be particularly beneficial for the rare and malignant Ewing sarcoma, which mainly affects children and adolescents. Mathematics professor Marta Fiocco has been awarded a substantial…

Veel mensen denken dat zware metalen giftig zijn en mens en natuur altijd schade aanbrengen. Dat beeld moet genuanceerd worden, vindt hoogleraar Sylvestre Bonnet.

The moment has finally arrived: after months of hard work, the strategic plan is finished. It was an interesting period, thinks core group member Sylvestre Bonnet. 'How we finally arrived at this strategic plan was very different from what I had thought beforehand.'

The development of the Faculty Strategic Plan (FSP) did not come to a standstill over the summer. We now have a draft version of the Plan that incorporates the feedback on the strategic objectives that we obtained from various meetings and bodies before the summer. The Research Directors and a number…

A new website has been set up that provides information about the government funded Law Sector Plan in the Netherlands, including the plans of the participating universities and developments within the agreed themes.

Leiden University Libraries (UBL) recently issued a new collection policy plan, containing priorities for the coming years regarding the formation, management, availability, and use of the UBL collection.

The aim is to involve as many faculty colleagues as possible in the development of the new Faculty Strategic Plan (FSP). So after several stakeholder meetings and information gathering, the ball is now in the court of four working groups with a variety of members. They will carry out a SWOT analysis…

In 2021, more than 2,600 students and staff members shared their ideas for Leiden University and the Strategic Plan for the coming years, under the banner of LDN>>>FWD. What will be the guiding principle for taking decisions? Which aspects will be emphasised? The last consultations have now been concluded…

Organisation

Valedictory lecture

Now the Dutch national Law Sector Plan has been positively evaluated, the temporary funding provided to Leiden Law School for the research projects ‘Institutions for Conflict Resolution’ and ‘Empirical Legal Studies’ will become structural.

Tuesday 7 June saw the finalisation of the new Faculty Strategic Plan 2022 – 2027 by the Faculty Board. A PDF of the Faculty Strategic Plan (FSP) will be available in Dutch and English for the faculty community in July. A number of members of the FSP Steering Committee look back on a far-reaching and…

One of the aims in the development of the university’s new strategic plan is to foster a dialogue between as many students, staff and external stakeholders as possible about which topics and ambitions should be included in the plan. At the beginning of May we therefore invited all our students and staff…

PhD student Janine Westendorp and her colleagues conducted literature research on what patients with cancer and their loved ones perceive as harmful communication from healthcare providers. The results were published in the journal Psycho-Oncology and are released as a poster to distribute to healthcare…

In its Strategic Plan Leiden University sets its direction for the coming years. A new plan will be presented next year, and in the runup to this we are organising different forms of student and staff consultation within the scope of LDN FWD (‘Leiden Forward’). A series of meetings were recently held…

ICT

Chemotherapy, but without hair loss or extreme fatigue. It may be possible if the toxic drug only becomes active where it is ‘switched on’ by light. Matthijs Hakkennes has helped bring that idea closer to reality and obtained his PhD cum laude. ‘I received many thank-you emails from China and Bangla…

Nausea, neurologic pain and hair loss: some of the severe side effects of chemotherapy. Not necessary, biochemist Liyan Zhang showed. Together with Leiden biologists and others, she achieved great results with a drug that is only active in combination with light. Zhang will defend her PhD on 4 July.

Leiden University is concerned about the plans presented by Minister of Education, Culture and Science Robbert Dijkgraaf to limit English-taught courses in higher education. If these plans go forward, the university believes this could have major consequences for our international students and staff.…

The new university Strategic Plan Innovating and Connecting 2022-2027 was presented during the Dies Natalis on 8 February 2022. Colleagues and students from our faculty also made contributions, inspired by the vision and strategy process underway in our faculty since 2019.

Education, Organisation, Research