865 search results for “taal immune responses” in the Public website
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High throughput microscopy for cellular adaptive stress response pathways in drug adversity
High throughput microscopy
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‘I always thought I was immune to stress, but now I’m not so sure’
Lecturers had a week to move their courses online. An enormous challenge because remote teaching definitely wasn’t commonplace at Leiden University. Suzan Verberne, a lecturer and researcher at LIACS, shares her experiences. ‘I tried to do too much in my first week working from home.’
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Whole-cell biosensor for label-free detection of GPCR-mediated drug responses in personal cell lines
Source: Biosens Bioelectron, Volume 74, pp. 233-42 (2015)
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Novel immunomodulatory drugs for tuberculosis treatment
Can drugs that target host signaling pathways be used to eradicate antibiotic-resistant bacteria?
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Metabolic signatures in nutrition and health: short-term diet response, sexual dimorphism and hormone chronobiology
The power of personalized nutrition lies in being able to conduct clinical research on healthy people while capturing metabolic markers sensitive to the impact of environmental and metabolic stressors (e.g. diet, changing sex hormones and the menstrual cycle).
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How partisan politics influence government policies in response to ageing populations
Kohei Suzuki is Assistant Professor at Institute of Public Administration. This study carries several important implications for understanding the policy impacts of a graying population and for studies of the welfare state, in general.
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A Priori Truth in the Natural World : A Non-referentialist Response to Benacerraf's Dilemma
The main question addressed in this thesis is how we can best conceive the contrast between a priori and empirical truths.
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Framing conditionality in times of crisis: EU institutional responses to Turkey’s democratic decline (2014–2024)
In this article, Seda Gürkan, Özlem Atikcan and George Christou examine how EU institutions responded to Turkey’s democratic decline between 2014 and 2024, analysing how conditionality was framed and applied by the European Commission, European Parliament and European Council.
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Many objective optimization and complex network analysis
This thesis seeks to combine two different research topics; Multi-Objective Optimization and Complex Network Analysis.
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Liposome-based synthetic long peptide vaccines for cancer immunotherapy
Promotores: Wim Jiskoot; Ferry Ossendorp
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Education
Please find here the BA- and MA-Courses taught on the subject of language learning at Leiden University.
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CHERRIES - Constructing Healthcare Environments through Responsible Research Innovation and Entrepreneurship Strategies
The project will support Responsible, Research and Innovation (RRI) policy experiments in the healthcare sector in three European territories: in Murcia (ES), Örebro (SE) and the Republic of Cyprus (CY). CHERRIES will engage the territorial stakeholder ecosystems in participatory agenda setting, need…
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interactions to unravel biomarkers for disease progression and treatment response
The aim of this project is to explore the use of statistical interaction models to quantify cross-omics and omics-drug interactions in large-scale clinical and experimental datasets
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Margo Donam.a.dona@biology.leidenuniv.nl | 071 5272727
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Protease-Responsive Targeted Delivery of Chemotherapeutics Holds Great Promise for the Treatment of Pancreatic Ductal Adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is the deadliest common cancer, with only 8% of patients surviving for five years. One reason for this poor outcome is that current chemotherapy treatments are highly toxic, often leaving patients too sick to receive treatment or forcing doctors to lower the dose…
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Maria Yazdanbakhshm.yazdanbakhsh@lumc.nl | 071 5265067
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Constructing an ‘emotional community’ in times of crisis: the EU’s response to Russia’s invasion of Ukraine in 2022
Emotions play a key role in EU politics. This article examines how emotions influence the EU’s response to international crises and norm violations.
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Isabella BrunnerFaculteit Governance and Global Affairs
i.brunner@fgga.leidenuniv.nl | 070 8009500
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Not just a protein machine: How ribosomes regulate immune response
PhD defence
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Inspirational practices in cultural heritage management: fostering social responsibility
This catalogue is the result of the EU_CUL project (2018-2021), which explores the use of cultural heritage in Europe for fostering academic teaching and social responsibility in higher education.
- Gender Approaches to Cybersecurity: design, defence and response
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Quantitative modelling of the response of earthworms to metals
Promotor: Prof.dr. W.J.G.M. Peijnenburg, Co-promotor: Dr. ing. M.G. Vijver
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Rosema & Louwerse, ‘Response scales in Voting Advice Applications’
Voting Advice Applications represent popular election campaign tools in many countries, enabling voters to discover which party or candidate provides the best match with their political preferences. Political scientists Martin Rosema (University of Twente) and Tom Louwerse (Leiden University) examine…
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Trading Responsibility: navigating national burdens in a globalized world
International trade has played a major role in defining the modern global economy. Trade, however, entangles the environmental pressures of economic sectors, giving the illusion of environmental improvements, while the opposite may be occurring.
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The Bulgarian governments' response to Covid-19
Emerging from the first wave relatively unscarred to an increase in infections. This research analyses the response from the Bulgarian government to Covid-19.
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Andrea BartolucciFaculteit Governance and Global Affairs
a.bartolucci@fgga.leidenuniv.nl | 070 8009506
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Illuminating Host Defence against Mycobacterial Infection: Interactions with Autophagy and LC3-Associated Phagocytosis
Despite substantial progress in understanding tuberculosis (TB), the eradication of the TB epidemic is still far from reach.
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Determining the most appropriate dose metrics for evaluating dose-response relationships of metal-based nanoparticles to Zebrafish embryos
Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver
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Environmental Refugees. A human rights-based, security and State responsibility approach
On 7 May 2020, Jolanda van der Vliet defended her thesis 'The International Legal Protection of Environmental Refugees. A human rights-based, security and State responsibility approach'. The doctoral research was supervised by Prof. N.J. Schrijver and Prof. J.J.C. Voorhoeve.
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Tussen taal en dialect
Lecture, Comparative Indo-European Linguistics (CIEL) Seminars
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Detecting cross-linguistic syntactic differences automatically
So far it has been impossible to compare large sets of syntactic constructions in large sets of languages systematically and automatically. The online availability of parallel text corpora and software tools to align, enrich, search and analyse them has the potential to make automatic massive systematic…
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understanding and provision of an enhanced and robust monitoring system for Responsible Research & Innovation (RRI)
Across Europe, the need for a more dynamic governance and a better societal integration of research and innovation is increasingly appreciated. Internal drivers of change (such as the digitalization of science) and political will to better align with societal needs and concerns are bringing about aspirational…
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The importance of friendships in reducing brain responses to stress in adolescents exposed to childhood adversity: a pre-registered systematic
Up to 50% of all children and adolescents growing up worldwide are exposed to at least one form of childhood adversity (CA), which is one of the strongest predictors for later-life psychopathology.
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Development of hyaluronan-based dissolving microneedle arrays for dermal vaccination
Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.
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Classical conditioning to improve immunotherapy in cancer
Can the conditioning paradigm be used for checkpoint inhibition cancer treatment?
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Education
An overview of the courses
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Annemarie Meijera.h.meijer@biology.leidenuniv.nl | 071 5274927
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When do bureaucrats respond to external demands?
This article examines to what extent bureaucratic responsiveness depends upon the source, the content and the salience.
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Fast vaccine design and development based on correlates of protection (COPs) Influenza as a trendsetter
New and reemerging infectious diseases call for innovative and efficient control strategies of which fast vaccine design and development represent an important element.
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Two-pronged attack on infectious diseases
A combination of two potential drugs gives hope of a 'super blockage' of an over-active immune system, Leiden researchers report in Nature. The breakthrough came from the crystallisation of a membrane protein.
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Certificate Dutch as a Foreign Language
The CNaVT exam is the official, international exam of Dutch as a Foreign Language for all who learn Dutch all over the world. The Catholic University of Leuven organizes the exam. The Dutch Language Union has commissioned this collaboration.
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Frank Baasf.baas@lumc.nl |
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Cornelis van Kootenc.van_kooten@lumc.nl | 071 5262148
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Mark van Buchemm.a.van_buchem@lumc.nl | 071 5264376
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Patrick van Hagep.van.hage@biology.leidenuniv.nl | 071 5274950
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MICA-mediated immunity: a new opportunity for improving corneal graft survival
Corneal transplantation is one of the most common human organ transplantations worldwide. Although the 1-year survival rate is as high as 90%, more than half of transplantation patients suffer various types of corneal rejection, such as epithelial rejection, chronic stromal rejection, and endothelial…
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Anita Liaoc.liao@lacdr.leidenuniv.nl | 071 5272727
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Towards the development of synthetic vaccines against tuberculosis
The research described in this Thesis was aimed at designing and synthesizing nature-inspired compounds as part of TB vaccine discovery.
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Parameter optimization toward optimal microneedle-based dermal vaccination
Microneedle-based vaccination has several advantages over vaccination by using conventional hypodermic needles.
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The unexplored functions of Toll-like receptor signaling: Immunometabolism, development and microbiome interactions
Toll-like receptors (TLRs) are central components of the innate immune system, functioning as pattern recognition receptors that detect microbial- and damage-associated molecular patterns and initiate antimicrobial and inflammatory responses.