489 search results for “bio-organische synthesis” in the Public website
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Cheminformatics: Analyzing small-molecule activity data
While bioinformatics methods deal with the analysis of sequence information (be it proteins or DNA), the field of cheminformatics is concerned with the analysis of small-molecule datasets.
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Allosteric modulation by sodium ions and amilorides of G protein-coupled receptors
Promotor: A.P. IJzerman
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Research schools in chemistry
The Leiden Institute of Chemistry actively participates in several national research schools for MSc and PhD students. These schools are consortia that stimulate collaboration between research groups of the different participating Dutch universities. The research schools also offer advanced training…
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Microscopy and Spectroscopy on Model Catalysts in Gas Environments
In surface science there is great effort to move from studying simple, flat model surfaces in vacuum to investigating more complex model catalysts in gas environments (in situ). This thesis gives three examples of such studies using microscopy and spectroscopy.
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Self Defense: Mimicking natural deterrent strategies in plants using adhesive spheres and volatiles
How can we make agricultural production systems more sustainable as the worldwide demand for healthy, safe food continues to grow? How can we develop healthy new food crops that have higher yields while requiring fewer harmful chemicals?
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Azafaros is valorizing a library of compounds
The company Azafaros was established in 2018 to translate innovative science from Leiden University and Amsterdam University Medical Center into novel disease-modifying treatment modalities for rare genetic metabolic disorders such as lysosomal storage diseases.
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Allosteric modulation by sodium ions and amilorides of G protein- coupled receptors
Promotor: A.P. IJzerman
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Integrating palaeoproteomics into the zooarchaeological analysis of Palaeolithic bone assemblages
Doctoral Thesis
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Multilevel governance and responses to the COVID-19 pandemic: a systematic literature review
In this article, the authors summarise the literature on the effects of multilevel governance on governments’ policy responses to Covid-19.
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Exploring the potentials of nurture: 2(nd) and 3(rd) generation explant human skin equivalents
BACKGROUND: Explant human skin equivalents (Ex-HSEs) can be generated by placing a 4mm skin biopsy onto a dermal equivalent. The keratinocytes migrate from the biopsy onto the dermal equivalent, differentiate and form the epidermis of 1(st) generation Ex-HSEs. This is especially suitable for the expansion…
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From data to models: reducing uncertainty in benefit risk assessment: application to chronic iron overload in children
M. Danhof, Co-promotor: O.E. Della Pasqua
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Heme biosynthesis and regulation in the filamentous fungus Aspergillus niger
Promotors: Prof.dr. P.J. Punt, Prof.dr. C.A.M.J.J. van den Hondel
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Michel Orrit and Hermen Overkleeft members KNAW
The Royal Netherlands Academy of Arts and Sciences (KNAW) selects prominent researchers as members based on their scientific achievements. On September 17th, the KNAW will install 21 new members, including Leiden physicist Michel Orrit and chemist Hermen Overkleeft.
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Metals for Catalysis and Sustainability
Central in coordination and organometallic chemistry is the synthesis of new chelating ligands, the synthesis and characterization of metal complexes with these ligands, and the study of their properties. An important goal in my research is to create understanding of the relation between the structures…
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Chemical biology of glucosylceramide metabolism: fundamental studies and clinical applications for Gaucher disease
How can we develop new chemical biology tools and approaches to understand and interfere with glucosylceramide metabolism in relation to Gaucher disease?
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PhD Theses
A full overview of MacBio PhD Theses.
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Ukraine
This is an Erasmus+ International Credit Mobility project of the Faculty of Science with the Taras Shevchenko National University of Kyiv.
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Covalent inhibitors of G protein-coupled receptors: the case of adenosine receptors
Supervisor: Xue Yang
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Leiden Academic Centre for Drug Research
The Leiden Academic Centre for Drug Research (LACDR) is a centre of excellence for multidisciplinary research on drug discovery and development.
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Polypept(o)ide-based nanostructures for therapeutic and diagnostic application
Nanoparticles exhibit a number of adjustable properties, e.g., their size, shape, and surface and core chemistry, which can be further diversified with different functional moieties. This opens a broad field for application in diagnostic and therapy. In this respect, the use of a polymeric hybrid material,…
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Molecular Physiology
Molecular Physiology is a research group at the Leiden Institute of Chemistry dedicated to the design, synthesis and application of chemical tools to study important biological and biomedical questions. The group is headed by Prof. Dr. Mario van der Stelt and includes the research lines of Assistant…
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Call overview
We are delighted to announce that Speech Prosody 2024 will be held in Leiden, The Netherlands (02–05 July 2024). The conference aims to showcase the facets of prosodic variation and their role in the production, comprehension, and acquisition of speech in order to obtain a better understanding of the…
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Galaxies and the structures in which they are embedded
Researchers at Leiden Observatory study the fundamental physics that creates structure in the Universe. These processes collect matter into galaxies and gas into stars. With the use of powerful telescopes and advanced calculations and computer simulations, Leiden astronomers seek to understand the origin,…
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Mission
Area studies is an approach to knowledge that starts from the study of places in the human world from antiquity to the present, through the relevant source languages, with central regard for issues of positionality.
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WISE Horizons
To facilitate and accelerate a systemic change in society by creating a framework based on the current post-growth narratives, policies, and initiatives.
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Master Projects
The following master research projects are currently open in the Bouwmeester group.
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Research
Research at the BIOSYN group is comprised of the following research themes:
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Clay in Common
Conference, Workshop
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Clever variant of antibiotic bypasses resistance in bacteria
Biological chemist Nathaniel Martin is going to test an alternative antibiotic that can combat common resistant bacteria such as MRSA. For this purpose, he will receive 350,000 euros from the NWO's NACTAR programme. ‘We want to know how safe and effective our antibiotic is in a realistic situation.’
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Hans van den ElstFaculty of Science
elst_h@chem.leidenuniv.nl | 071 5274275
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Thijs VoskuilenFaculty of Science
t.voskuilen@lic.leidenuniv.nl | 071 5272727
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Tim OfmanFaculty of Science
t.p.ofman@lic.leidenuniv.nl | 071 5274481
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Rian van den NieuwendijkFaculty of Science
nieuwend@chem.leidenuniv.nl | 071 5274483
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Indigo BekaertFaculty of Science
i.m.bekaert@lic.leidenuniv.nl | 000 0000000
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Helena EhrenFaculty of Science
h.l.ehren@lic.leidenuniv.nl |
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Gijs RuijgrokFaculty of Science
g.ruijgrok@lic.leidenuniv.nl | 071 5272727
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Laura van Vliet-van den DoolFaculty of Science
l.van.vliet@lic.leidenuniv.nl | 071 5276458
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Jorn de JongFaculty of Science
j.de.jong@lic.leidenuniv.nl | 071 5272727
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Kitt Emilie OsterlidFaculty of Science
k.e.osterlid@lic.leidenuniv.nl | 071 5272727
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Nico MeeuwenoordFaculty of Science
meeuwenoord@chem.leidenuniv.nl | 071 5274358
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Vincent LitFaculty of Science
v.a.j.lit@lic.leidenuniv.nl | 071 5272727
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Merijn VriendsFaculty of Science
m.b.l.vriends@lic.leidenuniv.nl | 071 5272727
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Kateryna BilaFaculty of Science
k.bila@lic.leidenuniv.nl | 071 5275604
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Patrick WeberFaculty of Science
p.weber@lic.leidenuniv.nl | 071 5274478
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Yevhenii RadchenkoFaculty of Science
y.radchenko@lic.leidenuniv.nl | 071 5272727
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Florian KüllmerFaculty of Science
f.kullmer@lic.leidenuniv.nl | 071 5272727
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Remco PeterFaculty of Science
r.e.a.peter@lic.leidenuniv.nl | 071 5272727
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Rebecca KatzyFaculty of Science
r.e.katzy@lic.leidenuniv.nl | 071 5272727
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Jurriaan HemingFaculty of Science
j.j.a.heming@lic.leidenuniv.nl | 071 5272727
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Koen RijpkemaFaculty of Science
k.j.rijpkema@lic.leidenuniv.nl | 31682056822