Mathematical and computational analysis of the dynamics of polar transport of the plant hormone auxin.

Promotor: S.M. Verduyn Lunel, Co-Promotores: S.C.Hille, O.W. van Gaans

In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.

A single self-assembled semiconductor quantum dot in a high-finesse optical microcavity - the subject of this thesis - is an interesting quantum-mechanical system for future quantum applications. For instance, this system allows trapping of an extra electron and thus can serve as a spin quantum memory,…

What role play stress and fear in forming of nocebo hyperalgesia?

To what extent can literary strategies deepen and enhance research in and through the visual and performing arts, as well as for research in academia?

Social anxiety and factors determining school success in children. Brain development in relation to cognitive, social and emotional development in adolescence.

This project looks at how the native language influences processing mechanisms of non-native language(s) as well has how it influences brain structure and functional connectivity.

Master projects are available in

This thesis investigates the connection between tonal realization and tone change (tone sandhi) in Wenzhou Chinese, and whether and how such a connection is conditioned by prosodic structure and focus marking.

Leiden has a strong tradition in theoretical physics, thoroughly linked with experimental disciplines.

Sound & Score brings together music expertise from prominent international researchers and performers exploring the intimate relations between sound, score and notation, and the artistic possibilities that this relationship yields for performers, composers and listeners.

The Leiden Institute of Physics (LION) offers bachelor and master level education in physics at Leiden University.

Source: PLoS ONE, Volume 10, Issue 3 (2015)

The thesis describes experimental steps towards reduction of friction on the macroscopic scale by scenarios of thermo- and superlubricity well-known on the nanoscale.

The GMP Facility facilitates development and production of Advanced Therapy Medicinal Products (ATMPs) and chemical (peptide) synthesis.

To improve treatment of breast cancer patients it is important to understand all stages of breast cancer from initiation to in situ disease and progression to invasive disease. In this thesis we use intraductal injections of patient derived tissue to model ductal carcinoma in situ and invasive breast…

On the 6th of July, wood specialists, members of the canoe club Natsec, a professional boat builder, volunteers of the Vlaardingen Broekpolder and students and staff of the Faculty of Archaeology of the Leiden University gathered on the waterfront in Vlaardingen. Two reconstructions of prehistoric canoes…

Tuberculosis causes 1.5 million deaths yearly and anti-tuberculosis therapies are threatened by emergence of drug resistance. Development of innovative drug combinations should be accelerated with the use of translational pharmacological models. Moreover, host-directed therapies (HDT), which stimulate…

The Physics and Quantum Matter and Optics specialisation is one of the two programmes Leiden offers in experimental physics. The programme can be tailored to individual needs and interests.

The Quantitative Pharmacology group headed by Coen van Hasselt focusses on the application of state-of-the-art quantitative pharmacometrics and systems pharmacology modeling combined with translational experimental models to develop personalized treatment strategies for antibiotics and to combat antimicrobial…

This thesis consists of two subjects, that are both a consequence of radiation pressure.

Political scientist Luzia Helfer (Leiden University) empirically tested claims about media-politics relatiopns using unique data from experimental studies with elected politicians and political journalists in Switzerland and the Netherlands.

Mechanical interactions between cells and their environment play an important role in many biological processes.

The interest of this thesis lies in spin transport in normal metals and superconducting half-metallic junctions.

The drug discovery pipeline is used to describe the stages in drug discovery. The earliest stage concerns with the identification of potential targets and molecules ('hits') that can modulate their function, while more advanced stages are about developing these hits into viable experimental drugs and…

The probability for dissociation of molecules on metal surfaces, which often controls the rate of industrially important catalytic processes, can depend strongly on how energy is partitioned in the incident molecule. There are many example systems where the addition of vibrational energy promotes reaction…

This thesis is an experimental study of the UV irradiation of the interstellar ice analogues, relevant for the different stages of the star and planet formation sequence.

In this thesis we use Josephson and noise scanning tunneling microscopy for the study of conventional, unconventional (iron-based) and disordered superconductors. On the one hand, Josephson scanning tunneling microscopy allows us to directly visualize the superfluid density with high spatial resolut…

Promotor: Prof.dr. M. de Jong, Co-Promotor: Dr. A.J. Heijboer

We study the dynamics of individual emitters in micro cavities.

Ecotox is a stimulating top-facility that provides an integrative research environment around the topic of ecotoxicological testing and experimental research. Research focus: Dose-response modelling Mode-of-actions and mechanism-of-actions Test method development, in view of targets in AOPs (adverse…

The emergence of complex diseases resulting from abnormal cell-cell signaling and the spread of infectious diseases caused by pathogens are significant threats to humanity. Unraveling the dynamic mechanisms underlying cell-cell signaling and infectious disease spreading is crucial for effective disease…

Research in the BioTherapeutics research programme is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.

In this thesis, we have used numerical approaches to study the effects of translational symmetry breaking on strange metallic systems as realised by the holographic duality⁠.

The study of tax law covers the tax system in its full width. It includes domestic, international and European tax law.

CrO2, a half-metal ferromagnet, has shown great promise for superconducting spintronics applications for nearly two decades.

This thesis explores interfacial conductance and electric field-effects in LaAlO3/SrTiO3 heterostructures.

Considering Mesoamerican Precolonial books as material objects

‘By cleverly combining new techniques for analysing DNA at the level of individual molecules, we can achieve real breakthroughs in research into conditions such as dementia,’ predicts Professor John van Noort. Together with four leading biophysics research groups, he has written a review article in…

Special achievements, grants and a top 10 ranking, a great calendar year for the Faculty of Archaeology! See the overview of 2023 in the hall of fame below.

Death, fire and identity in North-West Europe

How can the combination of sound composition, astrochemistry, and epistemological analysis provide new and unexpected insights into interstellar chemical reactivity?

Our group explores the larger domain of quantum measurement. In particular we investigate two themes that are closely connected: The detection of specially prepared quantum states of light and understanding and characterizing quantum photon detectors.

To what extent and in what manner can experimental video be used to reclaim the capacity for telling one’s own story, on one's own terms, speaking in tongues outside the linguistic framework of immune system discourse?

The CIGR comprises research groups from the Leiden Institute of Chemistry (LIC), the Leiden Academic Centre for Drug Research (LACDR) and the Leiden Institue of Physics (LION).

How does stress affect different components of behavioral impulsivity and aggression in patients with Borderline Personality Disorder compared to clinical controls (patients with Attention Deficit Hyperactivity Disorder) and healthy controls?

In the one-year Linguistics specialisation programme you will be able to focus on a specific thematic or disciplinary route, reflecting the linguistics expertise present at Leiden University.

Practical information about the physics summer school of Leiden University: the frontiers of modern physics. This page contains information about the cost and price of the summer school, the available scholarships, location, housing and the programme. This summer school is a part of the Leiden Insitute…