In the latest episode of DWDD University on 'Light', Prof. Robbert Dijkgraaf used a number of experiments from the Leiden Physics Practicum Lab. He showed why the sky is blue, that light is a wave phenomenon, how magnetism and electricity are connected and that white light consists of all colors of…

In the weekly magazine “Mare” from Leiden University, an interview with the Leiden statistics prof. dr. Richard Gill has been published recently about his contribution to the Delfts quantum-experiment.

Are you thinking about studying abroad for a semester? We came across two students who want to share their experiences with you.

The research conducted at the Leiden Academic Centre for Drug Research is clustered within the divisions of BioTherapeutics, Cell Systems and Drug Safety, Medicinal Chemistry and Systems Pharmacology and Pharmacy, and the Metabolomics and Analytics Centre.

In the specialisation Occupational Health Psychology, part of the Master in Psychology, you will integrate knowledge of several disciplines in psychology, with a clear focus on workers and their work setting.

We focus on a better understanding of the mechanisms of cancer drug resistance and metastasis.

In this project, we aim to develop mathematical models to mechanistically and quantitatively predict the dynamics of cellular stress pathway activation and its relation with toxic effects when cells are exposed to various toxicants.

Supervisor: Natalia Ortiz Zacarías

PhD defence

Supervisor: Anna Vlachodimou

In the second semester of this academic year (February 2025), the Faculty of the Humanities will switch to Ans for digital exams. Several lecturers have already gained experience with the new platform through pilot exams. Two lecturers from Dutch Studies, Liesbet Winkelmolen and Myra Arends, share their…

CERN has approved the construction and operation of SND@LHC, a neutrino detector at the Large Hadron Collider. It's a precursor for SHiP, a detector meant to detect dark matter. Leiden physicist Alexey Boyarsky is one of the initiators of both SHiP and SND@LHC.

Would you like to know more about our research using laboratory animals or our studies on alternatives to animal testing? If so, take a look at the news articles on the right-hand side of the page (for mobile users, see the bottom of the page).

Promotores: J. Jonkers, K.E. de Visser

The main aim of this thesis was to unravel the signaling and regulatory networks that drive tumor cell migration during breast cancer metastasis.

In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.

Source: J Med Chem (2015)

ChEMBL is a large-scale drug discovery database containing bioactivity information primarily extracted from scientific literature.

The focus of the described research in this thesis is on the oxidative stress response (Nrf2 pathway). The aim of the research presented in this thesis is to obtain more information concerning microRNAs which are involved in the Nrf2 pathway, to determine and evaluate the application of microRNAs for…

Double Bind. Public service professionals coping with contrasting demands. How do public service professionals align their PSM with contrasting demands set by the organizational and social contexts in which they work?

Epithelial-mesenchymal plasticity (EMP) and tumor cell migration play an important role in cancer progression, and an improved understanding of the mechanisms underlying these concepts is essential for developing new targeted approaches.

Developing new medicines is one of modern science's most significant hurdles, a process marked by high costs, long timelines, and frequent failures of promising candidates.

Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.

Animal models suggest that the chemokine ligand 2/CC-chemokine receptor 2 (CCL2/CCR2) axis plays an important role in the development of inflammatory diseases. However, CCR2 antagonists have failed in clinical trials because of a lack of efficacy.

Structure-affinity relationship (SAR) and structure-kinetics relationship (SKR) studies were combined to investigate a series of biphenyl anthranilic acid agonists for the HCA2 receptor.

Triple-negative breast cancer (TNBC) constitutes a small subtype (~15%) of breast cancer, but causes the majority of breast cancer-related deaths.

Drug induced organ toxicity is the main problem of the drug development and drug usage in the clinic. The liver and kidneys are the most sensitive organs towards drug induced toxicity.

Promotor: Prof.dr. B. van de Water, Co-promotores: J.W. van der Laan, C.L.E. Siezen

Local broadcaster Omroep West recently joined one of the University’s Summer Tours. These exclusive tours give you a peek behind the scenes at the Academy Building, P.J. Veth Building and Bibliotheca Thysiana: buildings with a long, rich history.

Our core themes, which our programmes are about, are: Public Affairs, Leadership, Political-Administrative Sensitivity, Safety and major social issues.

Bispecific antibodies with one Fab arm binding to effector cells, such as T-cells and NK-cells, while the other Fab arm recognizing a tumor associated antigen (TAA) can be used to redirect these effector cells for tumor specific killing. Using bispecific antibodies to treat hematological cancers is…

What is it like to study at the Humanities Faculty of Leiden University? Soon-to-be students experienced a day at university during the Experience Day 2017 and found out what studying really is about.

Seksueel grensoverschrijdend gedrag en structurele sociale onveiligheid horen niet thuis in vrouwengevangenissen, blijkt uit onderzoek van Leidse onderzoekers Esther van Ginneken en Yara Abbing. Zij vinden dat er een ingrijpende cultuurverandering nodig is en doen aanbevelingen.

This project aims to link robot development and policymaking to reduce the complexity in robot legal compliance in the context of COVR.

In the Bachelor’s in Security Studies you study 21st century security challenges and learn to devise strategic solutions to a complex world.

Course

What is it like to be a Leiden University student at Campus The Hague? These prospective students found out on the Experience Day of 30 March.

The cannabinoid receptor type 2 (CB2R) is associated with several inflammatory diseases with an unmet medical need (e.g. Alzheimers, multiple sclerosis, reumatoid arthritis). Development of new chemical biology strategies to study this protein is essential to aid future development of drugs for these…

The Young Academy Leiden and its workgroups have launched different initiatives in the interest of early-career scholars. To find upcoming events, check out our (social) media channels. Below you can see a selection of the initiatives YAL's workgroups have launched.

This project is funded by the Dutch Cancer Society. The project will be part of an ongoing research line aimed at identifying mechanisms of cancer therapy resistance and metastasis. In this project, it will be investigated how the Grainyhead family of transcription factors controls therapy response…

Division contact information & address

In the Drug Research theme, we primarily work with rodents. Rodents, such as mice, are one of the most common laboratory animals. These small mammals are easily housed and exhibit a rapid rate of reproduction.

This article examines the effects of introducing proportional representation (PR) in Polish local elections on women’s political representation.

The following dissertation reconstructs Paul Natorp's philosophical psychology. It argues that psychology's main object is the lived experience of concrete subjects, understood as a transcendental structure of logical-reflexive conditions for the recognition, appropriation, and evaluation of objective…

Last Saturday, Wijnhaven Campus and the Anna van Buerenplein were the setting for the first 'on campus' Experience Days in The Hague since the restrictive measures in higher education were introduced in March 2020. Spread over the day, some 200 students visited the campus to delve deeper into the 3…

Police, administrators and other parties will from now on have access to the advice of the new Academic Advisory Board for the Police. Maartje van der Woude, professor of socio-legal studies, is one of the members of this council.

Marieke Liem wrote a contribution for DJIzien, a magazine published by the Dutch Custodial Institutions Agency (Ministry of Justice and Security), about her meetings with long-term prisoners. ‘For my research on long-term prisoners I made numerous visits to Dutch prisons. During these visits, I came…

Are you interested in the BA programme International Studies but not yet sure what it all means?