Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).

The filamentous bacteria Streptomyces are widespread inhabitants of terrestrial soils.

Isotopic insights on human diet from the later stone age to Neolithic in Northwest Africa, Morocco

Promotores: J. Jonkers, K.E. de Visser

Within the field of astronomy, understanding how galaxies grow and evolve from the Big Bang to the present day is a challenging and complex question.

The dissertation by Max Kusters (PhD at ICLON) examined ‘teacher agency’: the capacity of university lecturers to actively and purposefully influence their teaching practices and work conditions.

The Pharmacy research group focusses on the development of predictive models to improve clinical drug efficacy and safety. We are moreover strongly involved in the Master specialisation of Pharmacy at Leiden University. We work on clinical problems that require further mechanistic understanding and…

Atherosclerosis is the most prominent underlying pathology of cardiovascular disease and an important cause of major adverse cardiovascular events.

On 16 January 2020, Maaike Wensveen defended her thesis 'Eigen haard is goud waard?'. The doctoral research was supervised by Prof. P. Nieuwbeerta and Dr. J.M.H. Palmen.

Promotor: S.M. Verduyn Lunel, Co-promotor: S.C. Hille

The main research question of this thesis was: Can nitrogen cycling on dairy farms on peat soil in the Dutch Green Heart area be improved by adapting management to the nitrogen supply from soil and by using other grassland species and crops without affecting milk production?

The Encyclopedia of Global Human Migration provides a complete exploration of the prominent themes, events, and theoretical underpinnings of the movements of human populations from prehistory to the present day.

Large carnivores and humans, along with their livestock, have co-existed for thousands of years. However, human population growth and an increase in economic activities are modifying the landscape for large carnivores and their prey.

How geographical and institutional openness in Dutch Guiana fostered a unique colonial economy. This publication is part of the Early American Places Series.

Here you can find products and research tools developed by the Navigation Lab Leiden

Patterns of paleomobility in the Caribbean were studied through an inter-disciplinary approach using a combination of archaeological, osteological, mortuary, and isotopic data.

The project aims to explore Eurasian elk's role in the ecosystems of the past and its relationship with humans through analysis of its distribution and habitat in the Netherlands.

Promotors: Prof.dr. G.R. de Snoo, Prof.dr. H. Leirs (Univ. Antwerpen), Co-promotor: H.H. de Iongh

Promotor: T. Schmidt

Promotor: Prof.dr. P.G.L. Klinkhamer, Co-Promotor: T.J. de Jong

An archaeological case-study of the Pointe des Châteaux, La Désirade and Les Îles de la Petite Terre micro-region, Guadeloupe, F.W.I.

Childhood obesity is an increasing health issue. In the first part of this thesis comorbidities in children with obesity were studied, concerning the diagnostic process and dosing regimens.

De lichtheid van literatuur: Engagement in de multiculturele samenleving (The Lightness of Literature: Engagement in the Multicultural Society) is a plea for the social relevance of literature. The book delves into an age-old debate about literature and social engagement, which has recently been reinvigorated…

The land question had a crucial formative influence on Mayo politics in the decades before the First World War and this book shows the part played by many prominent nationalist figures such as Davitt, O’Brien, Dillon and MacBride in shaping the political landscape in Mayo.

Promotor: E.F. Smets Co-promotor: J. Geml

This thesis is a (biased) journey through very different topics in astrophysics: quasars and new populations of active galactic nuclei, gravitational waves from merging black holes, and protoplanetary discs around young stars.

This thesis aims to enhance our understanding of galaxies by testing theoretical models of galaxy formation against observations, particularly in the cases of extreme systems which have been found to have an excess of baryonic mass in their central regions, in the form of either supermassive black holes…

How do Humanitarian Response Organizations (HROs) and Virtual & Technical Communities (V&TCs) collaboratively govern disaster sensemaking processes, and what challenges shape the effectiveness of these collaborations between 2010 and 2016?

Promotor: G.R. de Snoo

Humans can see the world through the eyes of other humans and imagine what they know, want, and intend. This competence is known as Theory of Mind.

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This article examines how immigration from Central and Eastern Europe influences political support for Eurosceptic parties.

In this region researchers at LUCL have specific expertise in studying Austronesian and Papuan languages. China is another important region where Leiden linguists conduct research.

On the 17th of January, Sarah Von Grebmer Zu Wolfsthurn successfully defended a doctoral thesis. The Leiden University Centre for Linguistics congratulates Sarah on this achievement!

Promotores: Prof.dr. C.A.J. Knibbe, Prof.dr. M. Danhof, Prof.dr. K. Allegaert (Leuven)

Promotores: H.A. Udo De Haes, P.M. Brakefield

Our everyday life consists of all sorts of spatial processes: we find our way to work, remember where we left our keys, and are able to pick up our cup of coffee. We study how the human brain processes such spatial processes. From a clinical perspective, we are interested in how acquired brain damage…

Promotores: C.A.J. Knibbe; J.N. van den Anker, Co-promotores: H.P.A. van Dongen; B. van Ramshorst

Une étude archéo-anthropologique de la céramique des sociétés caribéennes multiculturelles de la période précoloniale à nos jours

This thesis focuses on important life history traits and their trade-offs using two hexapod models. Particularly, the trade-off between immune defense and embryonic developmental speed is a central theme of this study.

An interdisciplinary collection of the best international scholarship on Muslim youth.

This thesis explores several aspects of these Early Old Babylonian Amorites.

Human civilization consumes a huge amount of fossil fuels, which has resulted in an atmospheric CO2 level which has not been higher in over 800 millennia.

Jaroslaw Kantorowicz, assistant professor at the Institute of Security and Global Affairs, isolated the reaction of the public to the potential breach of constitutional fiscal rules from the reaction of other players, such as the opposition, media and civil society organizations.

Mycoheterotrophy is a particular mode of life in which plants obtain carbohydrates from their associated fungal partners, instead of by using photosynthesis.

The Mid Upper Palaeolithic of Eurasia 30,000 - 20,000 BP

Understanding how galaxies form, interact, and evolve comes largely from comparing theory predictions with observational data. Numerical simulations of galaxies provide the most accurate approach to testing the theory, as they follow the non-linear evolution of gas and dark matter in great detail and…

Pulsars were first discovered in 1967 and since then the population has grown and expanded over several wavelengths.

Promotor: Prof.dr. M. Ubbink

Technological advances have an impact on our daily lives. They have also been employed by governments to manage border security, especially at controversial border crossings. Fences, heat sensors, heat cameras, drones and other hi-tech equipment that are currently being tested collectively produce a…