This thesis focuses on the application of lipid-based nanomedicine in drug delivery, including small molecular antitumor drugs and biomacromolecules including mRNA, and evaluates their biological performance.

The aim of the REACT Study is to examine whether baseline inflammation, and/or neuro-immune responses to stress in a sample of adolescents with experiences of childhood adversity predicts: the perception of stress, social behaviour and general mental and physical health during and after the COVID-19…

Light can be used to apply forces on single cells. Focused lasers have been used by physicists to tweeze particles and to manipulate them. These so called “optical tweezers” can be used as mechanical phenotyping tools for characterising the mechanics of materials and living objects.

PhD defence

An overview of the research at the Biologics Formulation group

At the division of Biopharmaceutics, we aim to develop and test new therapeutic approaches to limit or even prevent the development of atherosclerosis in order to reduce the number of acute cardiovascular syndromes such as myocardial infarction or stroke.

In STAYAHEAD data-intensive approaches are being developed to ”decode the human immunome” with a focus on a global vaccine strategy. They have developed a rapid mass spectrometric test to analyse in real-time large numbers of variants of SARS-CoV-2 and the host immune response, and use these data to…

The Leiden University Medical Center (LUMC) is committed to improving healthcare and the health of individuals. The LUMC staff put this mission into practice on a daily basis with their leading research, cutting-edge teaching and optimal, innovative healthcare.

The Ghent Rolin-Jaequemyns International Law Institute (GRILI) is a research institute within the Faculty of Law at Ghent University. Founded in 2015 at the initiative of Prof. Tom Ruys, the Institute brings together the existing expertise within the law school in the broader international law domai…

Pharmacologist Amanda Foks is one of the ten talented scientists who received a Dekker grant from the Hartstichting. She receives €427,000 to find a way to rejuvenate immune cells to prevent infarcts. Foks was nominated as Discoverer of the Year in 2016.

In our HANDS!Lab for Sign Languages and Deaf Studies, we run projects pertaining to sign language linguistics with a focus on Africa. In addition, we are running projects on sign language teaching, tactile signing, deaf people’s experiences with the legal system, and deaf history.

How does the human mind work when it comes to language? Why are some speeches totally persuasive, and others less so? How do children acquire language so effortlessly? How do languages develop over time? How many different speech sounds can humans make? During your BA in Linguistics, you will be immersed…

In the first year, the Linguistics programme provides a sound basis for specialisation and helps you develop your academic skills. In the second year, you will choose one of our four specialisations. While focusing on this track in your second and third year, you can also choose electives outside your…

The outbreaks of AIDS and COVID-19 showed clearly how infectious viruses can influence people’s lives. Investigating the changes in the host metabolism may provide a paradigm shift to consider immune-metabolic interactions as therapeutic targets.

Research in the BioTherapeutics research programme is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.

Yvonne Erkens, Associate Professor Labour Law, was a guest lecturer at the FHR Institute for Higher Education in Paramaribo, Suriname, from 4 to 11 November.

In this research group, led by Dr. Joost Beltman, the aim is to employ mathematical and computational dynamical modelling approaches in order to quantitatively and mechanistically understand the dynamical behaviour and regulation of intracellular networks of genes, proteins and metabolites as well as…

The Department of Medical Microbiology at Leiden University Medical Center (LUMC) is researching antiviral drugs that could treat and prevent SARS-CoV-2 in various projects. One part of the PanCoroNed project is being led by Martijn van Hemert and involves lab tests into the antiviral effect of molecules…

PhD defence

Was the progressive colonial civil servant the precursor of the postcolonial development-aid worker?

Political Islam is not new to the Middle East, but the appearance of ISIS has stretched the phenomenon to the extreme.

This project investigates how sign languages change and spread over time, and how this is influenced by their transmission history.

Leiden researchers are helping develop safe COVID-19 vaccines.

About nine million people worldwide contract tuberculosis each year. Research into new treatment for this disease has received fresh stimulus with more efficient techniques and a new understanding of how the tuberculosis bacteria works.

The research within the Division of Cell Systems and Drug Safety, headed by Prof. Bob van de Water, is focused on novel therapeutic modalities and novel concepts in early drug discovery, in order to develop more effective and safer therapeutic strategies. We generate advanced cell and computational…

About the book

Promotor: B. van de Water

Two excellent young chemists, Jeroen Codée and Sander van Kasteren, have received an ECHO grant for €260,000 from the Netherlands Organisation for Scientific Research (NWO). This funding will allow them to begin their research projects.

The previous blog post in this series discussed the role of international diplomacy during the coronavirus crisis. This post focuses on diplomacy and its challenges in post-corona times. Specifically, the blog post argues that diplomats will face a range of challenges following the Covid-19 pandemic…

The major aim is to examine the potential of learning the body to produce a similar physiological (autonomic, neuroendocrine, or immune) and physical (e.g., desensitization of persistent physical symptoms) response to placebo medication than to active medication (pharmacological conditioning). If proven…

PhD defence

PhD defence

Promotores: Prof.dr. G.F.A Kersten, Prof dr. J.A. Bouwstra

Psycho-physiological studies for health and disease.

The inverse electron demand Diels-Alder (IEDDA) pyridazine elimination emerged in 2013 as a new bioorthogonal reaction and constitutes a prime example of what is now known as dissociative bioorthogonal chemistry. The research described in this Thesis aims to develop synthetic strategies which enable…

Carbohydrates are present on the surface of bacteria making them suitable antigen candidates for vaccine development. This thesis deals with the synthesis of two carbohydrate-based components; the capsular polisaccharide of S. aureus type 5 and teichoic acids from staphilococci and enterococci speci…

2026

Research in the Lemay Lab concentrates on Iontronics: the physics of mixed electronic-ionic charge transport.

Researchers at Leiden University Medical Center (LUMC) and Radboud university medical center have been given the green light to deliberately infect volunteers with malaria in order to test a highly promising vaccine on them.

PhD defence

PhD defence

PhD defence

Linguistic research on a unique collection of Dutch letters allowed us to gain access to the every-day language of people from various walks of life. Private letters by men, women and even children have been elaborately explored in the Letters as Loot researchprogramme, initiated and directed by prof.…