814 search results for “team immune response” in the Public website
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Elizabeth BuimerFaculty of Social and Behavioural Sciences
e.e.l.buimer@fsw.leidenuniv.nl | 071 5273832
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How to share responsibility for polluting the atmosphere?
In our globalised economy, goods and services are frequently produced abroad. Is it the producer or the consumer that should be held responsible for greenhouse gas emissions associated with production? Together with colleagues from Berlin, Hauke Ward of the Institute of Environmental Sciences (CML)…
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Simcha Jong joins the SBB team
As of February the SBB team has expanded. Simcha Jong has joined the team as a Professor and Director of Science Based Business.
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Close call for Leiden Law team
The LLM Advanced International Civil and Commercial Law programme (ICCL) got off to a successful start last year. As a result of the academic bonds forged between staff and students Ilya Kokorin (ICCL student 2014-15) and Jeroen van der Weide (ICCL lecturer) took part in a competition for best comparative…
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The Global, Regional and Local Politics of Institutional Responses to COVID-19 - Implications for Women and Children
The shift from response to recovery is now noticeable as the world moves past the paralyzing effects of the COVID-19 pandemic. This book explores responses to the pandemic by international, regional, and local institutions, multilateral action, and crisis prevention efforts at different levels of governance,…
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Voluntary, Non-Binding Norms for Responsible State Behaviour in the Use of Information and Communications Technology: A Commentary
The United Nations Office for Disarmament Affairs (UNODA) has published the 2017 issue in their Civil Society and Disarmament series, titled Voluntary, Non-Binding Norms for Responsible State Behaviour in the Use of Information and Communications Technology: A Commentary. The series aims to provide…
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in science and innovation for Europe by adopting the concept of Responsible Research and Innovation (RRI)
The Project “Excellence in science and innovation for Europe by adopting the concept of Responsible Research and Innovation (NewHoRRIzon)” sets out to promote the acceptance of RRI in Horizon 2020 (H2020) and beyond. It will work out the conceptual and operational basis to fully integrate RRI into European…
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ANZUS cooperation in humanitarian assistance and disaster response in the Asia-Pacific: ships in the night?
In this article Vanessa Newby discusses how the ANZUS states of United States, Australia, and New Zealand that sit on the fringes of the Asia-Pacific, are increasingly using their armed forces to deliver Humanitarian Aid and Disaster Response (HADR) as a way of engaging with the region.
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Research lines
Physics and Engineering Approaches to Biomedicine and Pharmacology
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International organisations and the rule of law
International organisations that represent collaborations between States are becoming increasingly more powerful, and they have an increasing impact on our daily lives. For example, the European Court of Human Rights in Strasburg established that minors have a right to legal aid immediately following…
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Contagious Territories
In this project we think about the relationship between territory and contagion. Tracing the historical, political, and conceptual linkages between territorial bordering and migration on the one hand and disease related phenomena like contagion, immunity, and inoculation on the other, we ask how the…
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Team ICT in Business wins Strictly-for-Business Challenge 2012
On Monday 12 and Tuesday 13 March, the third edition of StrICTly for Business event was held at Papendal. Team
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Editorial: Responsibilities in the pursuit of employee well-being
What are we referring to when we talk about ‘good work’? And what does it mean to be a good employer? Helen Pluut and Merel Cornax address these questions in a recently published editorial.
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SBB team wins Philips Innovation Award
On Monday May 8th, two Leiden Startups took part in the finals of the Philips Innovation Awards. One Leiden venture, Levels Diagnostics, was selected as the winner of the €10.000,- price in the category of ‘Rough Diamonds’.
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Responsible alcohol consumption: 'It's good to pull together'
Anyone in Leiden wanting to join a student association has plenty to choose from. But the risk of alcohol abuse is a very real one. Leiden University, Leiden University of Applied Sciences and dozens of student associations have signed a new alcohol covenant that promises they will do their best to…
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Response to Brexit
We have followed the UK referendum of Thursday, 23 June 2016, with great interest and indeed concern.
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Cancer pathogenesis and therapy
With cancer, a person’s body cells grow uncontrollably. Putting together a detailed picture of how this comes about makes it possible to develop efficient therapies. Researchers at the Leiden University Medical Centre (LUMC) and Leiden University are working together to gain a better understanding…
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Health research and expertise at the IBL
We investigate the molecular basis underlying health and disease and provide answers to existing and emerging health problems. Within this theme, we study diseases ranging from rare genetic disorders to cancer and infectious diseases. We make use of a wide variety of model systems and pursue diverse…
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Life after a stem cell transplant: research on recovery and support
What is life like after a stem cell transplant? Haematologist Jennifer Tjon and nurse practitioner Kyra Oosterink from the LUMC are studying how patients experience recovery and what support they need.
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Tanzania
This is an Erasmus+ International Credit Mobility project of Leiden University’s Faculty of Medicine with Kilimanjaro Christian Medical Center in Tanzania.
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Marieke TollenaarFaculty of Social and Behavioural Sciences
m.s.tollenaar@fsw.leidenuniv.nl | 071 5273454
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Nanoparticles and Microfluidics for Future Tuberculosis Vaccines
Tuberculosis is a major global health problem caused by the Mycobacterium tuberculosis complex, claiming more than a million lives annually.
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Translational Immuno-Pharmacology
The Translational Immuno-Pharmacology group works on translating the efficacy of anti-infective therapy from preclinical (e.g. in vivo) to clinical, and is led by Rob van Wijk. Infectious diseases, such as tuberculosis, are in constant need of new therapies that work better, faster, and with less risk…
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Synthesis of oligosaccharide libraries from GBS capsular polysaccharides for structure-based selection of vaccine candidates
Glycoconjugate vaccines are composed of microbial poly- or oligosaccharides covalently linked to a carrier protein.
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Grant: Dr. Amanda Foks receives a prestigious Junior Postdoc fellowship from the Dr. E. Dekker stipendium awarded by the Dutch Heart Foundation
Dr. Foks obtained this fellowship for the project “Can promotion of efferocytosis induce regression of atherosclerosis?”, in which she aims to identify novel targets to promote regression of atherosclerosis. This research grant allows her to initiate independent research for the next three years.
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Targeting lipid metabolism to develop host-directed therapeutics for mycobacterial infections
Our research aims to develop drugs that boost the host immune response to better defend us against mycobacteria.
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mRNA and drug delivery with lipid-based nanoparticles
This thesis focuses on the application of lipid-based nanomedicine in drug delivery, including small molecular antitumor drugs and biomacromolecules including mRNA, and evaluates their biological performance.
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REACT Study
The aim of the REACT Study is to examine whether baseline inflammation, and/or neuro-immune responses to stress in a sample of adolescents with experiences of childhood adversity predicts: the perception of stress, social behaviour and general mental and physical health during and after the COVID-19…
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Sensing drug responses of single cells using optical tweezers
Light can be used to apply forces on single cells. Focused lasers have been used by physicists to tweeze particles and to manipulate them. These so called “optical tweezers” can be used as mechanical phenotyping tools for characterising the mechanics of materials and living objects.
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Student team invents Suckerspheres: sustainable alternative for microplastic
A Leiden Groningen student team has reached the European finals of the BISC-E competition. In this annual competition students have to come up with a sustainable solution to a major social problem. The team invented Suckerspheres: a natural alternative to the plastic microbeads that are still widely…
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Systemic Immune Dynamics in Cancer
PhD defence
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Freya Baetens speaks on shared international responsibility at GRILI
The Ghent Rolin-Jaequemyns International Law Institute (GRILI) is a research institute within the Faculty of Law at Ghent University. Founded in 2015 at the initiative of Prof. Tom Ruys, the Institute brings together the existing expertise within the law school in the broader international law domai…
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Amanda Foks receives Dekker grant from Dutch Hartstichting
Pharmacologist Amanda Foks is one of the ten talented scientists who received a Dekker grant from the Hartstichting. She receives €427,000 to find a way to rejuvenate immune cells to prevent infarcts. Foks was nominated as Discoverer of the Year in 2016.
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Research
An overview of the research at the Biologics Formulation group
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Research
At the division of Biopharmaceutics, we aim to develop and test new therapeutic approaches to limit or even prevent the development of atherosclerosis in order to reduce the number of acute cardiovascular syndromes such as myocardial infarction or stroke.
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Staying Ahead of the Virus
In STAYAHEAD data-intensive approaches are being developed to ”decode the human immunome” with a focus on a global vaccine strategy. They have developed a rapid mass spectrometric test to analyse in real-time large numbers of variants of SARS-CoV-2 and the host immune response, and use these data to…
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Leiden University Medical Center
The Leiden University Medical Center (LUMC) is committed to improving healthcare and the health of individuals. The LUMC staff put this mission into practice on a daily basis with their leading research, cutting-edge teaching and optimal, innovative healthcare.
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Arthur Rama.f.j.ram@biology.leidenuniv.nl | 071 5274914
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Global metabolomics and lipidomics approaches to probe virus-host interactions
The outbreaks of AIDS and COVID-19 showed clearly how infectious viruses can influence people’s lives. Investigating the changes in the host metabolism may provide a paradigm shift to consider immune-metabolic interactions as therapeutic targets.
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BioTherapeutics
Research in the BioTherapeutics research programme is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.
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Yvonne Erkens lectures on Corporate Social Responsibility in Suriname
Yvonne Erkens, Associate Professor Labour Law, was a guest lecturer at the FHR Institute for Higher Education in Paramaribo, Suriname, from 4 to 11 November.
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LUMC involved in development of novel drugs to treat and prevent SARS-CoV-2 and other coronaviruses
The Department of Medical Microbiology at Leiden University Medical Center (LUMC) is researching antiviral drugs that could treat and prevent SARS-CoV-2 in various projects. One part of the PanCoroNed project is being led by Martijn van Hemert and involves lab tests into the antiviral effect of molecules…
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Image-based Computational Biology
In this research group, led by Dr. Joost Beltman, the aim is to employ mathematical and computational dynamical modelling approaches in order to quantitatively and mechanistically understand the dynamical behaviour and regulation of intracellular networks of genes, proteins and metabolites as well as…
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Cellular immune profiles of Africans and Europeans in the context of vaccination and infectious diseases
PhD defence
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New Book by Margaretha Wewerinke-Singh – ‘State Responsibility, Climate Change and Human Rights under International Law’
About the book
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Noortje Dannenbergn.dannenberg@biology.leidenuniv.nl | 071 5274851
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High throughput microscopy of mechanism-based reporters in druginduced liver injury
Promotor: B. van de Water
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COVID-19 vaccine
Leiden researchers are helping develop safe COVID-19 vaccines.
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New techniques for tuberculosis treatment
About nine million people worldwide contract tuberculosis each year. Research into new treatment for this disease has received fresh stimulus with more efficient techniques and a new understanding of how the tuberculosis bacteria works.
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Cell Systems and Drug Safety
The research within the Division of Cell Systems and Drug Safety, headed by Prof. Bob van de Water, is focused on novel therapeutic modalities and novel concepts in early drug discovery, in order to develop more effective and safer therapeutic strategies. We generate advanced cell and computational…