974 search results for “been cancer” in the Public website
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Andraniek Evadgian -
Alfred Vertegaala.c.o.vertegaal@lumc.nl | 071 5269111
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Quantitative systems pharmacology modeling of biotherapeutics in oncology
In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.
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High throughput microscopy of mechanism-based reporters in druginduced liver injury
Promotor: B. van de Water
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Luca Giomi Group - Soft and Bio Mechanics
We are interested in understanding the mechanics of soft materials, of which biological materials are prominent examples.
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High school programmes
The Leiden Institute of Chemistry organises and participates in several programmes for high school students and teachers.
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Illuminating N-acylethanolamine biosynthesis with new chemical tools
In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.
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Thomas Schmidt Lab - Single Molecule Microscopy
Intrigued by the way cells autonomously regulate their fate, we strive to understand and visualize cellular processes as the basis of Cell Signaling.
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Systems microscopy to unravel cellular stress response signalling in drug induced liver injury
Promotor: B. van de Water
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Centre for Microbial Cell Biology
The CMCB brings together microbial cell biology expertise in Leiden. It aims at optimal resonance between the groups and maximal exploitation of the available infrastructure and to develop innovative cross-boundary technology platforms.
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Activity-Based Proteasome Profiling
Promotor: H.S. Overkleeft, Co-promotor: B.I. Florea
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Overview
The Division of BioTherapeutics at the Leiden Academic Centre for Drug Research (LACDR) is aimed at a smoother and speedier transition from preclinical research to pharmacological interventions, and the delivery of drugs in the human body by use of small molecules and biologics.
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Kinetics for drug discovery – The first step towards an improved drug discovery paradigm
Supervisor: Indira Nederpelt
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Introduction
Despite recent advances in medicine, many devastating disorders like cancer and cardiovascular, neurodegenerative and infectious diseases still lack effective treatments. In order to address this challenge, we, as scientists from Leiden University, joined hands in the LED3 network. LED3, for Leiden…
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NeCEN
With the powerful electron microscopes at NeCEN we study abnormalities in cells of blood vessels in cardiovascular disease, the interaction between pathogens and hosts in infectious diseases, molecular processes that cause cancer and the interaction between drugs and target proteins. Drug development…
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Synthetic Affinity-Based Probes for ADP-Ribose Interactome Studies
Adenosine diphosphate ribosylation (ADP-ribosylation) is a fascinating post-translational modification (PTM) that plays a role in a variety of cellular processes and is associated with several diseases, including cancer and viral infections.
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Intracellular allosteric modulators for human CC chemokine receptors
Supervisor: Natalia Ortiz Zacarías
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Immunologist Ton Schumacher wins NWO Stevin Prize
Ton Schumacher, professor by special appointment in Immunotechnology at the LUMC and group leader of Molecular Oncology and Immunology at the Netherlands Cancer Institute, has been awarded the NWO Stevin Prize. The Stevin Prize and the Spinoza Prize are the top scientific prizes in the Netherlands and…
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This is the library you did not know you had been looking for
2,240 plant extracts from 1,299 different plant species of Dutch origin. That’s the collection of the Dutch Extract Library, which has recently been transferred to the Institute of Biology Leiden. To plant biologist and contact person for this library Pingtao Ding this is a true treasury. ‘To bring…
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Niko Tinbergen lecture 2019: Stem cells, mini organs and eternal life
Three speakers, three fascinating science stories and a well-filled lecture hall. The Niko Tinbergen Lecture had a successful restart on 10 December 2019.
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End of the Lone Wolf: The Typology that Should Not Have Been
This research note argues that the “lone wolf” typology should be fundamentally reconsidered.
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postmortems of European foreign policy: should decision-makers have been surprised?
This paper develops a novel theoretical framework for the conduct of postmortems after major foreign policy surprises for the European Union and its member states.
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In memoriam: Juan José Jaime Aloísio Archidona Ramírez (1992 - 2024)
On Monday 26 February the terrible news reached us that our gifted former Egyptology student – and former student assistant at the Leids Papyrologisch Instituut – Juan Archidona Ramírez had succumbed to cancer.
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Vascular and Regenerative Medicine
Methods of treatment for chronic illnesses are limited. Doctors and researchers at Leiden University Medical Center (LUMC) and Leiden University are working on new therapies as an alternative for organ transplants. The goal is to cure the illnesses by restoring organs to their original function. Stem…
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Healthy ageing
The elderly accept may minor discomforts like stiffer muscles and getting tired more quickly, but they do want to go to their children's birthdays independently. Preventive elderly care helps people with that. The goal is to let people grow old while maintaining their self-reliance and independence…
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Research lines
Physics and Engineering Approaches to Biomedicine and Pharmacology
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SAILS
SAILS (Society, Artificial Intelligence and Life Sciences) is a universitywide initiative aimed at facilitating collaboration across disciplines on the use of Artificial Intelligence (AI). It is one of Leiden University's interdisciplinary programmes.
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The scientists behind LED3
Meet the scientists within the LED3 community
- Research Dossiers
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Two young female Leiden researchers join Oncode
The Oncode Institute is a new international network organisation that focuses on making sure that new scientific findings on cancer are implemented in patients as rapidly as possible. Two young female researchers at Leiden University have been selected to join Oncode: Laura Heiman (Leiden Academic…
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‘Creating propaganda has been democratised’
University lecturer Peter Burger has been researching the reliability of stories for almost 30 years. Whether political news item or urban myth, he debunks falsehoods and half-truths on an almost daily basis. He recently received a prize for his complete oeuvre.
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Workshops & Demo's
During the Leiden Science Family Day, you can take part in various workshops. You can also watch various demonstrations. Where will you go?
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Research with animals
At Leiden University, in both our biomedical and biological research, we use laboratory animals. Learn more about these specific areas of research and the goals we aim to achieve through these studies.
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Center for Interdisciplinary Placebo Studies Leiden
The Center for Interdisciplinary Placebo Studies Leiden (IPS) aims to advance the understanding of placebo and nocebo effects, their underlying mechanisms, and their potential applications in clinical practice. IPS consists of a group of interdisciplinary researchers working at Leiden University with…
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Research
Research at the MCBIM group is comprised of the following research themes:
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Cell Observatory: visualising structures of life
From molecule, to cell, to organism. The high-level drug research at the Cell Observatory aimes at reducing the spread of cancer and developing new medicines for tuberculosis.
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Stephan Raaijmakers: 'Humans and systems have to learn to understand each other better'
You can ask virtual assistant Siri about the weather, but you can’t have a real conversation with it yet. You can’t refer to anything that’s been said before, or ask the system why it says what it says. Stephan Raaijmakers, Professor by Special Appointment from TNO, hopes to change this.
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Education
Education & outreach
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Centre for Interdisciplinary Genome Research
The CIGR brings together a diverse range of unique expertise in genome research rooted in biology, chemistry and physics. Members of the CIGR investigate genome folding and genome transactions. An important aspect is direct as well as long term relevance for medicine.
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Bio-Pharmaceutical Sciences (MSc)
The master’s programme of Bio-Pharmaceutical Sciences at Leiden University examines the research area of bio-pharmaceutical sciences and drug research. It offers seven specialisations ranging from BioTherapeutics to Industrial Pharmacy.
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Biomedical Sciences Health
The Biomedical Sciences Health specialisation aims to provide you with a theoretical background and academic competences in multidisciplinary research in Biomedical Sciences and in clinical practice in Medicine. Since the programme is partly taught in English and partly in Dutch, fluency in Dutch is…
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Events
LIACS organizes different lectures and seminars like the LCN2 Seminars and SAILS Lunch Time-seminars.
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Biomedical Sciences Research
The Biomedical Sciences research specialisation aims to provide you with a theoretical background and academic competences in multidisciplinary research in Biomedical Sciences. The entire programme is taught in English.
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Archive
On this page, you will find the recordings of the Tuesday Talks since April 2025. Recordings of the precursor to the Tuesday Talks, This Week’s Discoveries, are also available here.
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Research
Research at the BIOSYN group is comprised of the following research themes:
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Awards and Grants 2023
On this page you will find an overview of awards and prizes granted to our staff and students in 2023, as well as special appointments at Leiden University and other institutions.
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Marcel Tijstermanm.tijsterman@lumc.nl | 071 5269111
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Ferry Ossendorpf.a.ossendorp@lumc.nl | 071 5263800
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Christi van Asperenc.j.van_asperen@lumc.nl | 071 5266090
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Peter Devileep.devilee@lumc.nl | 071 5269510