147 search results for “bioactive molecules” in the Staff website
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Lina Bayona Maldonado
Science
l.m.bayona.maldonado@biology.leidenuniv.nl | +31 71 527 4791
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Nicola Thome
Science
n.u.thome@biology.leidenuniv.nl | +31 71 527 4395
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IBL Spotlights - Bioactive molecules
Lecture
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IBL Spotlight - Bioactive Molecules
Lecture
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ERC grant to further investigate next-generation antibiotics with reduced toxicity
The European Research Council (ERC) has awarded Nathaniel Martin a Proof of Concept (PoC) grant. With it, his group aims to make a dangerous but potent antibiotic less toxic. He receives €150.000.
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Annemarie Meijer
Science
a.h.meijer@biology.leidenuniv.nl | +31 71 527 4927
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Discovery Leiden nominated for KIJK: Best Tech-idea of 2021
Using artificial intelligence to find new antibiotics. With that, researchers from Leiden University are nominated by magazine KIJK for the Best Tech-idea of 2021. From September 14 onwards people can vote to crown one of the nominees as the winner.
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NWO grant gives way to more sustainable production of antibiotics
The opportunity to explore a new, exciting research topic. That is how Lennart Schada von Borzyskowski describes his successful application for the NWO XS grant. It comprises 50,000 euros, which the researcher from the Institute of Biology Leiden (IBL) will spend on investigating a more sustainable…
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Collaboration starts quest for new antibiotics through NWO fund
Identifying novel antibiotic compounds to tackle antibiotic-resistant bacteria. Researchers from Leiden University and VU Amsterdam will unite through a project now funded by NWO’s Open Technology Programme (OTP), which awarded the collaboration nearly one million euros.
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Revolutionizing plant protection strategies: Ding lab receives 2.4M grant to investigate plant immunity
Plant biologist Pingtao Ding, assistant professor at the Institute of Biology Leiden (IBL), has received a 2.4 million European grant from the European Research Council (ERC). This ERC Starting Grant for promising young researchers allows him to unravel the molecular mechanisms by which plants resist…
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These eleven Leiden Science researchers are among the most highly cited
Eleven researchers of the Faculty of Science are on the 2021 Highly Cited Researchers list of Clarivate Analytics. Only 0.1 per cent of researchers are included in this list, literally making them one in a thousand.
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Awaken sleeping antibiotics with ERC Advanced grant
To facilitate the search for new antibiotics. That is the aim of Gilles van Wezel, professor molecular biotechnology at the Institute of Biology Leiden (IBL). He wants to do this by looking at similarities in the DNA of antibiotic-producing bacteria. Van Wezel has been awarded an ERC Advanced grant…
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Low-temperature spectroscopic studies of single molecules in 3-D and on 2-D hosts
PhD defence
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Record number of registrations for PhD course microscopy
‘Microscopy is by far the least understood, most inefficiently operated, and the most abused of all laboratory instruments,’ reads the quote on the office wall of microscopy unit supporters Joost Willemse en Gerda Lamers. It describes exactly why the two developed the microscopy course for starting…
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Researchers tackle antibiotic-resistant bacteria
When a bacterium becomes more resistant to one antibiotic, it sometimes becomes more sensitive to another. To better understand this interaction, researchers from the Leiden Institute of Biology (IBL) and the Leiden Academic Center for Drug Research (LACDR) under supervision of Daniel Rozen and Coen…
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'I have always worked for a better world. Here at Biology we do the same'
The new institute manager of the IBL studied biology for six months, but went in a completely different direction: development cooperation and the financial sector. Three decades later, Resi Janssen is making a radical career switch. Or isn’t she? 'In ten years’ time I want IBL to be in a new, sustainable…
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Surprising molecule helps detect protoplanets
A team of scientists, including Leiden Astronomer Alice Booth, has discovered silicon monosulfide molecules in the dust disk around a young star. Such molecules indicate planet formation. The team made the discovery using the ALMA telescopes. This method provides an alternative when direct observation…
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Modified caffeine molecules help medical research move forward
Before researchers can develop targeted drugs, they need to know exactly how a disease works. Biochemist Bert Beerkens created molecules that allow them to find out. He used caffeine as the basis for new molecules that enable research into certain receptor proteins on cells.
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What do complex molecules tell us about star formation?
How do you progress from an immense gas cloud somewhere in the universe to a star with planets? Research by Astronomy PhD student Martijn van Gelder sheds more light on the earliest phases of this process. He will receive his doctorate on November 24th.
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Tracking the origin and evolution of molecules in space
How do molecules originate and evolve in space? And how does that ultimately determine the chemical composition of planets and their atmospheres? The Dutch Astrochemistry Network (DANIII) receives 1.6 million euros from NWO to find out. A large group of Leiden astronomers and chemists is contributing:…
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Michel Orrit
Science
orrit@physics.leidenuniv.nl | +31 71 527 2727
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Sander van Kasteren: from molecule builder to Professor of Chemical Immunology
Sander van Kasteren only noticed some small, subtle changes since he was appointed professor on 1 May. Still, he has to get used to the idea, even though he had been working towards the professorship for a few years. ‘I don't quite see myself as a professor yet.'
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Remus Dame
Science
rtdame@chem.leidenuniv.nl | +31 71 527 5605
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Dennis Hetterscheid
Science
d.g.h.hetterscheid@chem.leidenuniv.nl | +31 71 527 4545
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ERC Advanced Grants for four Leiden researchers
From a new generation of antibiotics and more-effective vaccines to a map of dark matter and new light on Hindu traditions. Four researchers from Leiden University have received a prestigious €2.5m ERC Advanced Grant to develop their research.
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Geert-Jan Kroes
Science
g.j.kroes@chem.leidenuniv.nl | +31 71 527 4396
- IBL Spotlights
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Systematics, biogeography and bioactivity of the genus Phyllanthus L. and related genera of tribe Phyllantheae (Phyllanthaceae)
PhD defence
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Laura Heitman
Science
l.h.heitman@lacdr.leidenuniv.nl | +31 71 527 4558
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Marcel Schaaf
Science
m.j.m.schaaf@biology.leidenuniv.nl | +31 71 527 4975
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Fatema Zahra Rashid
Science
f.z.m.rashid@lic.leidenuniv.nl | +31 71 527 1037
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Amin Moradi
Science
moradi@physics.leidenuniv.nl | +31 71 527 5676
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Single-molecule microscopy in zebrafish embryos
PhD defence
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Single-molecule fluorescence in sequence space
PhD defence
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Optoplasmonic Detection of Single Particles and Molecules in Motion
PhD defence
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Highly Accurate Simulations and Benchmarking of Molecule-Surface Reactions
PhD defence
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The hunt for frozen organic molecules in space
PhD defence
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Alireza Mashaghi Tabari
Science
a.mashaghi.tabari@lacdr.leidenuniv.nl | +31 71 527 4425
- IBL Symposium 2022
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Dynamics of Single Protein Molecules by Temperature Cycling under Laser Heating
PhD defence
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Biological Origami at molecular level: folding a single protein
Human cells are protecting their proteins from unfolding and aggregating. That's what biophysicist Alireza Mashaghi and his team discovered after seven years of in-depth research into the folding mechanisms of proteins. With an unprecedented approach, the team was able to study the folding of a single…
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Lindsey Burggraaff wins Krijn Rietveld Memorial Innovation Award
Data scientist Lindsey Burggraaff has won the second edition of the Krijn Rietveld Memorial Innovation Award. She receives the prize for her research into bioactive substances in food. ‘Burggraaff's work is situated at a unique intersection of data science, biochemistry and the fields of food and nutrition,’…
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‘Look beyond your own discipline’
Good research means looking beyond disciplinary boundaries, said Professor of Molecular and Cellular Biochemistry Remus Dame in his inaugural lecture on 10 May. Processes that take place on DNA shouldn’t only be researched in a test tube but also in living cells, for instance.
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Hunting for life’s building blocks at minus 250 degrees Celsius
James Webb life’s building blocks
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Developing drugs with artificial intelligence
Developing new drugs is a difficult process. With the aid of artificial intelligence, Pharmaceutical scientist Xuhan Liu has developed methods that can help make drug design cheaper and faster. PhD defence on 15 February.
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With this algorithm, new medicines can be found more quickly
Did he dare take a gamble with his PhD research? Jeroen Methorst didn’t have to think long about it. It could fail or turn out very well. The latter is the case. Methorst developed a computer system that helps researchers find the protein they need. ‘Our whole group is now using this program.’ Methorst…
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Versatile antiviral proteins discovered with supercomputer
A single tiny molecule that can destroy flu, corona, HIV and Zika viruses? Yes, it really does exist. Biophysicist Niek van Hilten, who will receive his doctorate on 14 September, contributed to this discovery.
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Making the invisible visible with ‘click chemistry’
Sander van Kasteren (Professor of Molecular Immunology) makes the invisible visible. He will explain more in his inaugural lecture.
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Superselective bonds light up
Rather than one key and one strong lock, biology often uses tens or hundreds of weaker links to bind parts together, such as cells membranes. This allows for selectivity and also reversibility: the binding can also be undone. Researchers first caught this phenomenon using spheres or colloids, and published…
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Madouc Bergers made her own enzyme inhibitors for her bachelor’s thesis
For her bachelor’s thesis, Molecular Science and Technology student Madouc Bergers synthesized her own molecule that can inhibit the breakdown of sugars. Although most students do not even manage to make one building block, Madouc made three. Partly because of this, she has been nominated for the Science…