137 search results for “breast cancer metastasis” in the Staff website
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Review on “Anticancer opportunities at every stage of chemokine function” is featured on the cover of TIPS
Last November, Dr. Natalia Ortiz, Martijn Bemelmans (MSc), and Prof. Laura Heitman published a review in Trends in Pharmacological Sciences (TIPS) on targeting the chemokine system in cancer (https://doi.org/10.1016/j.tips.2021.08.001). The review was written in collaboration with Prof. Tracy Handel…
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‘Everyone in healthcare realises that something has to change’
Good, accessible and affordable healthcare is increasingly difficult to provide. Martin Schalij from the LUMC understands that this can keep people awake at night.
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New potential drug suppresses chemotherapy induced neuropathic pain
Oncode Investigator Mario van der Stelt and his colleagues have discovered a new potential drug that suppresses chemotherapy induced neuropathic pain.
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University flag travels to Mount Everest and back again
Leiden PhD candidate Mona Shahab climbed Mount Everest two years ago to raise money for the education of disadvantaged children in Egypt. She made it to the top and posed there with the University flag. She recently presented the flag to Rector Carel Stolker.
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Eduard Fosch-Villaronga and Hadassah Drukarch win European Commission’s Product Safety Award
The EU Product Safety Award encourages and honors innovative business initiatives and research that make a difference for consumers. This year, the Gold Medal was awarded to Eduard and Hadassah for their innovative research on diversity in robot design, testbed, and safety standardization
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Vidi grants for 12 researchers from Leiden University
An impressive 12 researchers from Leiden University have been awarded an 800,000-euro grant by the Dutch Research Council (NWO). This will enable them to develop their own line of research over the next five years.
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Veni grant for ten Leiden researchers
Ten Leiden researchers have been awarded a Veni grant by the Dutch Research Council (NWO). The grant, of up to 280,000 euros, will enable them to elaborate their ideas over a period of three years.
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Countering nerve pain caused by chemotherapy with new drug
Nerve pain is one of the most common side effects of chemotherapy. It is therefore one of the biggest reasons for cancer patients to stop treatment early. Darcy Reynolds worked on new drug candidates against this pain during her bachelor's thesis. She developed a new series of molecules that increase…
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ERC-grant for Sebastian Pomplun to cure disease by controlling gene expression with synthetic transcription factors
Sebastian Pomplun receives an ERC starting grant of 1.85 million Euros in five years. He wants to develop synthetic transcription factors that can enter cells and activate or deactivate specific genes. For example to disrupt cancer-related processes or to trigger the production of an important missing…
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Anja Rüten-Budde wins the C.J. Kok Jury Award for best thesis
Statistician Anja Rüten-Budde has won the C.J. Kok Jury Award 2020. Her PhD thesis resulted in an app which helps patients with soft tissue sarcoma and their doctors to make well-considered choices about the treatment. ‘Her work is interdisciplinary and directly relevant for society,’ the jury state…
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Tazuko van Berkel and Noel de Miranda join Young Academy
Leiden researchers Tazuko van Berkel (Greek and Latin Language and Culture) and Noel de Miranda (Tumour Immunology, LUMC) will join the KNAW’s Young Academy next year. They will be inducted on 22 March 2021.
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Bioart plays with genetic building blocks
Biotechnological developments are moving fast. From genetically modified plant varieties we are now moving to cultured meat. These developments require moral interpretation - and they get it in the form of art. Lotte Pet wrote a dissertation about it.
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A quick call with Corinda van Bohemen about the SteunLeiden.nl crowdfunding platform
From an emergency fund for Ukrainian students to a golf tournament for cancer research at the LUMC: the Leiden University Fund (LUF) crowdfunding platform is full of fantastic projects that enrich the university. If you are looking for funding for your idea or special project, crowdfunding may just…
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Erik Danen new Dean of the Graduate School of Science
The Graduate School of Science starts 2024 with a new Dean. The Faculty Council appointed Erik Danen for the coming four years. He succeeds Eric Eliel, who has held the position since May 2020.
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Richard Karlsson Linnér: ‘I expect a future where a genetic test will be as much a no-brainer as getting X-rayed.’
Assistant Professor Karlsson Linnér, who works at the Department of Economics, is one of the recipients of a Veni grant. His research on the accuracy of preventive genetic testing is a fine example of the intersection of economic science and law.
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Guest lecture by 113 on suicide prevention
Lecture
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In memoriam: Juan José Jaime Aloísio Archidona Ramírez (1992 - 2024)
On Monday 26 February the terrible news reached us that our gifted former Egyptology student – and former student assistant at the Leids Papyrologisch Instituut – Juan Archidona Ramírez had succumbed to cancer.
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New professor Suzan Verberne aims to bring large language models and search engines closer together
Suzan Verberne has been appointed professor of Natural Language Processing at the Leiden Institute of Advanced Computer Science (LIACS) from 1 October. Verberne has been at LIACS since 2017 as group leader of the Text Mining and Retrieval group.
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“You look well,” said the oncologist, but she didn't feel that way at all
Leiden psychologists Janine Westendorp and Liesbeth van Vliet have investigated types of communication that seriously ill patients may experience as harmful. The results of this research were published in the American journal Cancer. And the results have now also been published as a poster for education…
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Statistics for the benefit of the patient
Marta Fiocco has been appointed as of 1 April as professor of applied mathematics, in particular medical statistics. Fiocco's appointment is at the Faculty of Science and at the Leiden University Medical Centre (LUMC). She conducts research into 'personalised medicine', tailor-made medicines for cancer…
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Four Leiden researchers awarded Rubicon grants
Four promising young researchers will be able to conduct two years of research at a university abroad thanks to a Rubicon grant from the Dutch Research Council (NWO). The Leiden laureates are Renske Janssen, Girija Josh, Anne van der Meij and Yana van der Weegen.
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With 30 million dollars, this consortium aims to tackle tuberculosis
Thanks to a clever research method, progress is being made in the quest for better tuberculosis medications. Within an American consortium that received a 30 million dollars grant, Leiden researcher Rob van Wijk plays a significant role. ‘The next breakthrough in tuberculosis research will come much…
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PhD-Postdoc event 2022
Last October, we organized our annual PhD-Postdoc event at Kasteel Oud-Poelgeest. An important part of the program was a speed dating session with LACDR alumni.
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‘Pharmacogenetics will become part of patient care’
Does medicine make patients feel better or worse? We are getting better at predicting this from people’s DNA profiles, says Professor Jesse Swen. ‘It never fails to fascinate me how one DNA base pair can have such a huge effect on treatment with medication and the outcome.’
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Eight professors receive double appointment simultaneously
Delft, Nov. 15th, 2022 – Today, eight professors were simultaneously inaugurated as ‘Medical Delta professors’ at Leiden University, LUMC, TU Delft, Erasmus University and/or Erasmus MC. With an appointment of two or more of these five academic institutions, they combine technology and healthcare in…
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What Works in Suicide Prevention? Lessons from the 113 Helpline
Lecture
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Researchers discover how malaria parasite survives in mosquitoes
Researchers from Leiden University Medical Center (LUMC) have discovered how malaria parasites escape the immune system of mosquitoes. The so-called QC enzyme changes proteins on the outside of the malaria parasite such that the immune cells are unable to recognise the parasite. As a result, the parasite…
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Sander van Kasteren: from molecule builder to Professor of Chemical Immunology
Sander van Kasteren only noticed some small, subtle changes since he was appointed professor on 1 May. Still, he has to get used to the idea, even though he had been working towards the professorship for a few years. ‘I don't quite see myself as a professor yet.'
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How ‘sleeping’ microorganisms can determine the fate of a population
Microorganisms that temporarily ‘go to sleep’ play an important role in the evolution and survival of a population. Mathematician Shubhamoy Nandan conducted research on the effect of this characteristic called ‘dormancy’ in a novel mathematical model.
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Inexhaustible source of human heart muscle cells allows strong reduction of animal testing
Researchers at the Leiden University Medical Centre (LUMC) have managed to culture human heart muscle cells on a massive scale. This is an exceptional achievement because it is very difficult to replicate heart muscle cells outside the body. Using a special technique, the researchers have now created…
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In Memoriam: Stephen Haigh (1957-2022)
With the passing of Stephen Haigh on 9 September 2022, Leiden University's Institute of Political Science has lost a dedicated and inspiring instructor.
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Campus Square renamed: Rosalind Franklin Square
On World DNA Day 25 April, Leiden University is pleased to focus the spotlight on Rosalind Franklin, whose name was given earlier this month to the Campus Square on the Leiden Bio Science Park. This square will now be known officially as the Rosalind Franklin Square.
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LACDR PhD-Postdoc event - 12 October 2022
On October 12th, the LACDR PhD-Postdoc event will be organized in castle Oud Poelgeest.
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Surprising results of research on counterterrorism: 'Assumptions surrounding Trump may be wrong’
It poured down when Alexander Gallo received his diploma from West Point Military Academy. A bad sign, people said back then. It was June 2001, three months before 9/11. The now 46-year-old American fought in Iraq, did research in Afghanistan and stands in Leiden today, defending his dissertation on…
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Medical Delta professor Marco van Vulpen: ‘I advocate the introduction of the share factor’
Proton therapy is a new way of treating cancer in which radiation doses are delivered more precisely. This results in less damage to surrounding tissue and fewer side effects. Professor Marco van Vulpen is medical director of HollandPTC in Delft, where the social value of this therapy is studied. Van…
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How does the ethics committee work? Suzan Verberne gives an insight
How ethical is research involving humans and robots? And can research on artificial intelligence cause problems when it ends up in the wrong hands? In any research involving humans or their data, the ethics committee assesses where the issues are. Associate professor at LIACS Suzan Verberne chairs the…
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X-ray mirrors: useful in space, but also for radiation therapy
A special type of mirror to reflect X-rays has more possible applications than space research. Targeted radiation therapy for cancer, for example. Next to his full-time job, physicist David Girou mapped out the possibilities. He will receive his PhD on 14 June.
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A call about: the national university funds campaign
Various thought-provoking questions have been appearing online and in print adverts. They are part of a national university funds campaign in which the Leiden University Fund (LUF) is also participating. We wanted to find out more, so we called LUF Director, Lilian Visscher.
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Superselective bonds light up
Rather than one key and one strong lock, biology often uses tens or hundreds of weaker links to bind parts together, such as cells membranes. This allows for selectivity and also reversibility: the binding can also be undone. Researchers first caught this phenomenon using spheres or colloids, and published…
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Young, sleeping memory cells are crucial in fighting a reinfection
Researchers from the Netherlands Cancer Institute, the Leiden University Medical Center (LUMC) and Oncode have created a tracking system that can reveal how often cells have divided. This allowed them to find a yet undiscovered population of immune cells: young memory cells that behave like stem cells.…
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From lab discovery to a new drug: the Venture Challenge makes it possible
A breakthrough from the PhD research of medical chemist Elmer Maurits may help patients with autoimmune diseases and blood cancer in the future. But bringing a discovery from the lab to the clinic is not so easily done. Thanks to NWO's Venture Challenge, Maurits and his team will receive ten weeks of…
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Artificial microswimmers work together like bacteria
Microscopic swimmers such as bacteria do not always swim alone. There are advantages to exchanging information and cooperating. Stefania Ketzetzi and colleagues now show in Nature Communications that human-made microswimmers, too, can cooperate.
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In memoriam: Dr Andrzej Antczak (1956-2024)
On February 28th of this year Dr. Andrzej Tadeusz Antczak died of cancer after a long battle. Until his retirement in 2023 Andrzej was attached to the Faculty of Archaeology as an Associate Professor in Caribbean Archaeology. From 2017 until 2020 he was the Head of the Department of World Archaeology,…
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Making the invisible visible with ‘click chemistry’
Sander van Kasteren (Professor of Molecular Immunology) makes the invisible visible. He will explain more in his inaugural lecture.
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Seeking new concepts to treat diseases
Scientific Director of the Leiden Academic Centre for Drug Research (LACDR) Hubertus Irth: ‘We test substances and look for new concepts for treating disease.’
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Leiden research project on circular electronics receives 3.8 million euros from NWO
Fewer CO2 emissions, less airborne viral transmission, and a more sustainable form of food production: seven consortia of researchers and societal partners will put a budget of 32 million euros towards developing technological innovations. Important Leiden research on circular electronics by Prof. Dr.…
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Archaeologist Mette Langbroek works on beads exhibition: ‘Humans have a special relationship with beads'
Beads are among the oldest types of human artistic expression. Even so, the small ornaments have a bad status record regarding archaeological investigation. PhD candidate Mette Langbroek, usually at home studying early medieval beads, had the opportunity to work on a publication and exhibition on 5000…
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BrAInpower exhibition: tremendous and troubling uses of AI in our daily lives
Care robots, medical treatments, deepfakes and self-driving cars all with the aid of artificial intelligence (AI). The BrAInpower exhibition at Rijksmuseum Boerhaave shows spectacular applications of AI and explains how it can make such huge leaps. Bas Haring, Professor of Public Understanding of Science,…
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Five Leiden professors installed as Medical Delta professors
On 2 November, nine professors were simultaneously inaugurated as ‘Medical Delta Professor’ at Leiden University, LUMC, Delft University of Technology, Erasmus University and Erasmus MC. With an appointment at a minimum of two of these five academic institutions, they combine technology and healthcare…
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Leiden researchers visualise the 'guardian of our genome’
The guardian of our genome, the protein MutS, scans the DNA for spelling errors and makes sure they are corrected. An essential process for our health. Researchers at Leiden University Medical Centre (LUMC) have discovered precisely how this protein works by making MutS visible with cryo-electron microscopy.…