1,062 search results for “optimize drug design” in the Staff website
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LUMC will administer first Dutch stem cell gene therapy to patients
Researchers and clinicians at Leiden University Medical Centre (LUMC) are about to begin a milestone clinical study. It will be the first time a stem cell gene therapy developed in the Netherlands is used in a clinic. The therapy will be used to treat children with SCID, a rare disorder where children…
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Perovskite-based Photoelectrochemical Investigations for Artificial Photosynthesis
PhD defence
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Microphysiological liver systems for in vitro modeling and industry implementation
PhD defence
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Acquired resistance in pancreatic cancer: characterization and exploration of actionable targets of a multifactorial disease
PhD defence
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Herman SpainkFaculty of Science
h.p.spaink@biology.leidenuniv.nl | 071 5275055
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Grada DegenaarsFaculty of Science
g.h.degenaars@lacdr.leidenuniv.nl | 071 5274530
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Show me the money: the magic of the marketing and finance interface to drive financial performance in hospitality operations
PhD defence
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E-Values for Anytime-Valid Inference with Exponential Families
PhD defence
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GIREP-EPEC 2025 Conference, Leiden
Conference
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Government Policies and Scientific Collaboration symposium
Conference
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How e-coaching helps people with chronic kidney disease to live more healthily
An e-coaching programme helps people with chronic kidney disease, particularly in areas that patients themselves want to work on. ‘A healthy lifestyle is important for patients with kidney disease: it can slow down the loss of kidney function and there will be fewer complications,’ Katja Cardol explains…
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Voice of the ocean
There are many tributaries to Rosalin Kuiper’s story and they all lead to the sea. The 28-year-old sailor was one of the five-person Team Malizia in the world’s most prestigious sailing competition: the Ocean Race.
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The annual interview is changing: from scores and numbers to more human dimensions
Speaking with your manager more often, focusing explicitly on well-being and giving more recognition and rewards for teamwork and team performance: the annual Performance & Development (P&D) interview will have a new format and also a new name. With the acronym GROW (Gesprekken over Resultaat, Ontwikkeling…
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Personal Professional Skills Lab: a certificate for the development of FSW bachelor students
In line with the university and faculty ambition: ‘Future-oriented development of students’, from now on all FSW bachelor students can follow a three-year elective, faculty programme with certificate for personal-professional development, the programme starts with current first-year students; they are…
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Open science means better science
Leiden University has an active open science community. Open science means transparency in all phases of research by precisely documenting every step of the way and making this publicly available. ‘It’s time to be open,’ say psychologists Anna van ’t Veer and Zsuzsika Sjoerds. There is increasing awareness…
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How these young researchers are preparing for their first scientific conference
Three Psychology students will present a poster of their thesis research on Alzheimer’s and dementia at the international conference AAIC Neuroscience Next. ‘I remind myself to recognise - without fear or shame - when I don't know something.’
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Director of the MIVD General Swillens visits ISGA to talk about intelligence cooperation
On 15 December, Director of the MIVD General Jan Swillens, visited the Institute of Security and Global Affairs (ISGA) to give a lecture on international intelligence cooperation together with ISGA/NLDA researcher Pepijn Tuinier. This event, co-organised by the Intelligence and Security Group and the…
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Peter van Bodegom on sustainable horticulture
Dutch greenhouse horticulture is a world leader when it comes to innovative capacity and sustainability, but ‘the challenges are great in terms of energy, water, environment and biodiversity,’ says Peter van Bodegom, coordinator of AgriFood at the Centre for Sustainability of the Leiden, Delft, Erasmus…
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Faculty Strategic Plan 2022 – 2027 finalised
Tuesday 7 June saw the finalisation of the new Faculty Strategic Plan 2022 – 2027 by the Faculty Board. A PDF of the Faculty Strategic Plan (FSP) will be available in Dutch and English for the faculty community in July. A number of members of the FSP Steering Committee look back on a far-reaching and…
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70 years Mathematical Institute - growth, prosperity and (mathematical) challenges
Floreat et crescat. Flourish and grow. That was what was wished for the Mathematical Institute at its opening. Now, the institute proudly celebrates its 70th anniversary. Time to reflect on how it all began. And importantly, how is it doing now?
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Postdoc Adam Benfer stewards big data in the study of Central America
In the spring of 2024 the Faculty of Archaeology welcomed a new postdoc. Dr Adam Benfer, originally from the United States, occupies a double position as a researcher in the project of Alex Geurds and as the Faculty’s Data Steward. ‘It is pretty much what the title says: I steward data. Essentially,…
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PhD candidate Sinéad is a Europaeum Scholar: ‘There’s no other programme quite like this’
Sinéad Mulcahy recently started the Europaeum Scholars Programme, a two-year policy and leadership course for a group of thirty talented and committed PhD candidates from universities across Europe. She is already enthusiastic – both about the programme and her fellow scholars. ‘I would like to bring…
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Rethinking Urban Renewal and Citizen Engagement: Insights from Turin
Maria Vasile's ethnographic fieldwork in Turin reveals that volunteering and citizen engagement may not empower residents or allow them to shape their cities. Her analysis of urban gardens, food markets, and food aid initiatives calls for a broader perspective on urban peripheral areas and a shift away…
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Drs. Isabelle van de Calseyde and dr Sjef Houppermans presented with high French honour
“Very French and very impressive.” Those are the words drs. Isabelle van de Calseyde used to describe the reception at the French embassy residence in The Hague on 2 June 2015. There, she and dr. Sjef Houppermans were presented with an distinction for their remarkable services to the French language…
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Separate and holistic solutions to the problems of cross-border death and gift taxation
The response of international organizations to the problems of cross-border death and gift taxation needs to be revisited, according to PhD candidate Vassilis Dafnomilis. PhD defence on 3 June 2021.
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New statistical method brings together studies at an early stage
During the coronavirus pandemic, scientists were in a hurry to find drugs that would help fight the disease. To combine the research that was being carried out around the world, PhD candidate Judith ter Schure developed a new statistical method: ALL-IN meta-analysis. This helps determine sooner whether…
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Using low sample volumes to better understand brain diseases
Marlien van Mever delved into the analysis of tiny samples, cerebrospinal fluid from transgenic mouse models for example. She validated methods that can now be used to study brain diseases such as migraine and epilepsy. Van Mever will receive her PhD on 14 June.
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Jasper’s day - from Leiden to Brussels to Voorschoten
On Monday, 13 October, Jasper will travel to Brussels with a delegation from Key Region Leiden. Why is this collaboration important? And who will he be having dinner with that same evening in Voorschoten? Jasper shares his account of a long and interesting Monday.
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Smart monitoring of test subjects is the future of clinical research
Knowing whether or not a treatment is working just by wearing your watch? Data scientist Ahnjili ZhuParris has identified a lot of opportunities for the use of machine learning in clinical research to monitor test subjects at home.
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Alumnus Charlotte Poot developed a hospital app for children
Charlotte Poot (31) is co-founder and chair of Hospital Hero, an app that prepares children for a hospital visit. She studied and obtained her PhD at the LUMC.
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Jasper's Day
Jasper Knoester is the dean of the Faculty of Science. How is he doing, what exactly does he do and what does his day look like? In each newsletter, Jasper gives an insight into his life.
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‘Exposure therapy’ for bachelor students: preparing for the reality of scientific research
Already during their bachelor’s programme, students in Pharmaceutical Sciences are presented with challenging projects. One of these is the Bachelor Research Assignment (BOO in Dutch), which is often their first real experience with scientific research. This means a lot of responsibility and failures,…
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Veni grant for ten Leiden researchers
Ten Leiden researchers have been awarded a Veni grant by the Dutch Research Council (NWO). The grant, of up to 280,000 euros, will enable them to elaborate their ideas over a period of three years.
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Night of Discoveries: 3D-printed paintings and the effects of psychedelics
Come to the Night of Discoveries art and science festival on 16 September. Various researchers from the university are speaking at the festival.
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Biological Origami at molecular level: folding a single protein
Human cells are protecting their proteins from unfolding and aggregating. That's what biophysicist Alireza Mashaghi and his team discovered after seven years of in-depth research into the folding mechanisms of proteins. With an unprecedented approach, the team was able to study the folding of a single…
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Ine Tijdens on forty years at LACDR: ‘No two days were the same’
She walked into the Sylvius building as a wide-eyed twenty-something in 1984, and next year, she’ll be leaving us as a soon-to-be retiree in her sixties. Ine Tijdens (66) reflects on more than four decades at LACDR. ‘One year, I got a little whip for Sinterklaas. That says something about my persona…
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Flu stops when you block the enzyme that cleaves off virus particles
A flu virus could cause a pandemic. And then we would be poorly armed because flu viruses are starting to become resistant to flu medications like Tamiflu. Chemist Merijn Vriends successfully worked on an improved version of such medications. He will be awarded his doctorate on September 12th.
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Student mental health problems still common but less so than in covid year 2021
The number of students suffering from stress and anxiety has decreased slightly compared with 2021. But around half still suffer from mental health problems. This is according to the National Mental Health and Substance Use Monitor.
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Minor Violence Studies: interesting encounters and flying wooden blocks
The English taught interdisciplinary minor Violence Studies looks into various facets of interpersonal violence. Is this minor for all Leiden students? These two 'colleagues' are certain of it.
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Four burning questions for four inspiring international alumni
Last week on Monday evening, four international Leiden Law School alumni working in various sectors and areas of expertise came back to their alma mater to talk to current students. So who are these alumni?
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Aafje de Roest: ‘As an expert in Dutch Studies you have the right skills to research hip hop’
Aafje de Roest turned her hobby into her job. She went from a teenager who enjoyed listening to hip hop music to a PhD candidate who focuses on how Dutch hip hop music shapes the cultural identity of young people in the Netherlands.
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Pride is a celebration, but also a fight for visibility
‘Be yourself. Be as gay, queer, trans as you can and show the world you exist.’ These rousing words from Looi van Kessel marked the start of the third Pride Leiden for the university boat, with the theme: ‘450 years of being yourself’.
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GTGC lunch seminar series: an international, interdisciplinary scope
Starting February 6, the Leiden interdisciplinary research programme Global Transformations and Governance Challenges (GTGC) will host a lunch seminar series on pressing global governance issues. The series will feature researchers from various disciplines. It promises to be a trove of inspiration and…
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Leiden biologists find nanoplastics in developing heart
Nanoplastics can accumulate in developing hearts, according to a study by biologist Meiru Wang from Leiden University. Her research on chicken embryos sheds new light on how these tiny plastic particles pose a threat to our health.
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Awaken sleeping antibiotics with ERC Advanced grant
To facilitate the search for new antibiotics. That is the aim of Gilles van Wezel, professor molecular biotechnology at the Institute of Biology Leiden (IBL). He wants to do this by looking at similarities in the DNA of antibiotic-producing bacteria. Van Wezel has been awarded an ERC Advanced grant…
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Five Leiden contributions to NWO Perspectief projects
Five consortia within the Perspectief programme that include Leiden researchers have received funding to start their research projects. These projects focus on (further) developing technological innovations, with societal and economic impact at their core.
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Using health data for scientific research isn’t that simple
While health data is essential for scientific research, that data also needs to be protected. In her doctoral thesis, Irith Kist found a balance between protecting the individual and exchanging health data.
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Leaving Afghanistan: ‘Tensions with Russia and China are rising further’
After an extremely painful conclusion, the Western allies have left Afghanistan and the Taliban have regained supremacy. How will Afghanistan move forward, and what does the departure mean for global relations? Rob de Wijk, emeritus Professor of International Relations and Security, analyses the failure…
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How to make cryptographic techniques more efficient?
Sharing scientific data, transferring money, or sending other sensitive information online: with cryptography, applications make sure your data does not fall into the wrong hands. Mathematician Thomas Attema (CWI/TNO/Leiden University) helps with this. For his PhD research, he developed a new technique…
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How NeCEN helped develop the Johnson & Johnson Covid-19 vaccine
The Phase 3 clinical trial results of the promising Covid-19 vaccine of Johnson & Johnson are expected this month. The Dutch electron microscopy facility NeCEN helped develop the company’s vaccine, and they have now published their scientific findings in Nature Communications.