De crèche en het klaslokaal zijn misschien wel de meest gunstige plekken voor ziekteverwekkers. Toch is er relatief weinig bekend over hoe kinderen reageren op virussen en bacteriën en hoe het komt dat sommige kinderen veel beter beschermd zijn dan anderen. Simon Jochems, onderzoeker aan het Leids Universitair…

Phage therapy is a novel yet unmatured therapeutic approach in the face of the crisis of antimicrobial resistance (AMR). Dr. Tingjie Guo received a grant from the Elise Mathilde Fund and the LUF to develop innovative phage-antibiotic combination treatment strategy for combating AMR.

Rob van Wijk (LACDR, Leiden University) and Robin van den Biggelaar (LUCID, LUMC) have been awarded a €10,000 euro KIEM grant from Leiden University to start an interdisciplinary collaboration to investigate the potential of AMPK activation as an adjunctive therapy to enhance tuberculosis treatment.

Bacteria temporarily live without their cell wall if dangerous viruses are near. A remarkable feature, as the cell wall is a sturdy barrier against threats. Still, the discovery has a logical explanation ánd might be of a consequence for fighting pathogenic bacteria, according to Véronique Ongenae,…

Leiden researcher Anne-Grete Märtson brought together a large number of studies to better understand antibiotic dosing in patients with obesity. The publication in a renowned medical journal has already garnered much positive reactions, Märtson says. ‘It’s high time researchers started sharing more…

Organisation

Organisation

Three researchers from Leiden University have been awarded a Starting Grant by the European Research Council. The subsidy will allow the researchers to set up their own projects and put together a research team.

Cryogenic memories, antibiotic treatment for urinary tract infections and recycling plastic sustainably. These are the subjects of the three NWO-XS grants awarded to Leiden Science researchers.

The antibiotic EVG7, developed in Leiden, has proven capable of fighting the dangerous gut bacterium C. difficile with only a minimal dose. What’s more, the bacterium is far less likely to return, a major issue with existing antibiotics. The research was published in Nature Communications.

Four university medical centres, including the LUMC, are joining forces to increase pandemic preparedness in the Netherlands.

Resistance to antibiotics is a major problem in health care. Thanks to a grant from the Elise Mathilde Fund and the LUF, pharmacologist dr. Coen van Hasselt can look for new dosing schedules to reduce the development of antibiotic resistance.

'What nature made isn’t necessarily an optimized medicine to use in the human body,’ says Professor of Biological Chemistry Nathaniel Martin. That’s why a group of Leiden researchers is making a chemistry-based improved version of the frequently used antibiotic vancomycin. They received an NWO NACTAR…

Infecting each other with viruses and bacteria while protecting yourself with medicines and vaccinations. Sounds like a fun evening, right? Master students Life Science & Technology Rafael Jezior and Dennis de Beeld certainly think so. Together, they developed ImmunoWars: an exciting card game based…

Effectively treating a severe case of pneumonia is often challenging. Identifying the pathogen behind it can be difficult. PhD candidate Ilona den Hartog tried something new: ‘We searched for answers in substances our own body produces.’ PhD defence on 17 September.

eLaw - Center of Law and Digital technologies from Leiden Law School, and the Vascular Surgery Department at Leiden University Medical Centre in the Netherlands, join forces to explore the use of AI for diabetes and secondary prevention of diabetic foot problems and won a prize for it.

When a bacterium becomes more resistant to one antibiotic, it sometimes becomes more sensitive to another. To better understand this interaction, researchers from the Leiden Institute of Biology (IBL) and the Leiden Academic Center for Drug Research (LACDR) under supervision of Daniel Rozen and Coen…

Two consortia led by Leiden researchers have been awarded over one million euros by the Dutch Research Council and the Ministry of Health, Welfare and Sport to find solutions to antimicrobial resistance.

Fungi germinating in the lungs of patients. Doesn’t sound too nice, does it? Luckily, humans can deal with this normally, and we are able to clear the infection before anything comes to harm. However, in people with health issues, Aspergillosis can cause a lot of damage, especially if the fungus becomes…

When a bacterium becomes resistant to one antibiotic, it may sometimes become more sensitive to another. This biological side-effect offers an unexpected opportunity in the fight against antibiotic resistance.

Cancer research generates massive amounts of data, but traditional tools often fail to fully harness their potential. How can we unlock this data to provide better treatments for cancer patients? PhD candidate Marina Gorostiola González explored this by using advanced data analysis techniques to guide…

How do you keep participants engaged in your research from start to finish? And how do you connect your research with a wider audience? As a science communication adviser, Eva Slings works with researchers at Psychology on these and other questions. Colleagues share their experiences.

Building a sustainable, international and interdisciplinary consortium for developing evidence-based communication strategies about Antimicrobial Resistance. That is the objective of a new project between researchers from Leiden University, VU Amsterdam and Stellenbosch University in South Africa, made…

On 21 April 2022, Cleveringa Professor Jan Grabowski visited Leiden. The theme of his visit was the role of law and historiography in shaping collective memories.

Multidrug-resistant pathogens and worldwide pandemics are increasing, making infectious diseases more prevalent. To develop new treatments, deeper knowledge of the interaction between bacteria and human cells is required. Ariane Briegel recently became a Medical Delta professor and studies such path…

Three Leiden professors have recently been awarded the most prestigious scientific accolade in the Netherlands: Maria Yazdanbakhsh and Marc Koper have been awarded a Spinoza Prize and Judi Mesman a Stevin Prize. They received their prizes on 13 October.

Dying from viral infection due to organ failure and blood loss: we still know little about how it can happen. Among other things, Huaqi Tang developed an organ-on-a-chip to figure it out. 'These technologies can offer unprecedented opportunities to fight the viruses that threaten our society.' Tang…

Researchers from Leiden University, University of York, University of Barcelona/IQTCUB/ICREA and The Francis Crick Institute report a new class of experimental compounds that powerfully block influenza viruses. The findings offer a potential new strategy for treating flu infections and preparing for…

With the aid of artificial intelligence (AI), care professionals at the LUMC (Leiden University Medical Center) are able to calculate quickly and accurately whether a coronavirus patient has suffered serious lung damage. They do this by putting a CT scan through the AI software of the CAD4COVID-CT p…

About one and a half million people worldwide die each year from tuberculosis. For thirty years, therapy with antibiotics has been the same, while it takes far too long and can lead to resistant pathogens. Leiden researchers from four institutes are now joining forces to develop more effective and efficient…

Researchers at Leiden University have created a unique model that mimics how disease develops after a dengue infection. This 'dengue-on-a-chip' model helps them study the virus more effectively. The timing is crucial, as climate change is causing dengue to spread worldwide.

Our lecturers are back on campus sooner than the rest of the staff. Away from their screens and in live contact with students: many lecturers are relieved, but some are concerned. Have sufficient steps been taken at our teaching locations? What about ventilation? We spoke to Michel Leenders who, as…

Every year, an NWO PhD in the Humanities grant is awarded to a prospective PhD candidate at the Faculty of Archaeology. This year, the grant went to Maia Casna, enabling her to study respiratory disease in the past. ‘My hypothesis is that the rapid formation of cities in the medieval Netherlands, must…

“Is it possible to restore antibiotic sensitivity in resistant bacteria?” Dr. Tingjie Guo wondered. “Watch me and learn”, phage responded. Dr. Tingjie Guo received an open competition XS domain ENW grant from the Dutch Research Council (NWO) to investigate the evolutionary trade-off of antimicrobial…

A team of LACDR scientists from three different divisions (SPP, BT, MC) contributed to a book on "Substance P in Health and Disease," which will be published by Elsevier. The project was a collaboration with Hannover Medical School (Germany) and was coordinated by Alireza Mashaghi. Master students Ehsan…

An impressive 22 research projects by Leiden researchers have been awarded Veni funding from the Dutch Research Council (NWO).

The shock wave triggered by one of the five galaxies making up the iconic Stephan’s Quintet appears to be less disruptive than previously thought, with the shock likely being cushioned by dust particles in the surrounding gas. This is according to the analysis of the first scientific observations of…

After an intensive tender procedure, Leiden University and the Municipality of Oegstgeest have chosen Dura Vermeer for a new housing development with plenty of affordable homes in Nieuw Rhijngeest-Zuid. Dura Vermeer seeks to create a green and playful neighbourhood with welcoming public spaces as its…

The history of the LGTBI+ collective, deeply marked by episodes of violence, repression, and discrimination, is also the history of the struggle for social change and the conquest of civil rights, advances without which contemporary Western democracies could not be explained. More recently, the implementation…

From medicines from snake venom to supercrops and the origin of words. Thirteen researchers from Leiden University will receive Open Competition XS grants from the Dutch Research Council (NWO).

On January 24 Professor Annemarie Meijer and Dr Sander Wezenberg received a NWO grant for their research. The grant was awarded within the Open Competition Domaine Science-M programme and is intended for innovative research areas that can form the basis for the research themes of the future.