671 search results for “single molecule biophysics” in the Staff website
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Procurement, purchasing and ordering
Do you wish to purchase or order something on behalf of the University? You need to take into account a number of procurement procedures. For example, the University makes use of framework contracts. Do you do need temporary staff? You can read all about it on the page of HR.
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Education Dashboard
Leiden University’s Education Dashboard contains key data for all the university’s degree programmes. Please note that at present the dashboard is only available in Dutch. For more information see the Dutch staff website or send an email to cijfers@bb.leidenuninv.nl.
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Manuals
Do you want to install software yourself at your workplace? Or would you link to sync your work email with your smartphone? On this page you will find all our ICT workplace manuals, sorted by theme.
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Institutional accreditation and audit (ITK)
Higher-education institutions must be assessed and accredited once every six years to ensure they provide a high standard of education. You may be asked to speak to the assessment panel during the institutional audit.
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New faculty policy on earned income: clarity and fair rules
Finance
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Functional MRI Analysis (Basics)
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Designing the quantum future on a regular computer
Computer scientist Tim Coopmans uses pen, paper and regular computers to simulate the best possible quantum computer. He tells about his research and how this helps make a useful quantum computer a reality a little bit sooner. ‘I hope I will get to see quantum computers contributing something really…
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European Central Bank’s centralised application of national law under the Single Supervisory Mechanism: A rule of law analysis
PhD defence
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Professor by special appointment Jeroen van Zon joins the Institute of Biology
As of 1 September, Jeroen van Zon started as professor by special appointment in Quantitative Developmental Biology at the Institute of Biology Leiden (IBL). Van Zon is also group leader of Quantitative Developmental Biology at the physics research institute AMOLF. Three questions about his new role…
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LACDR introduces ‘Digital Labcoat’ for Biopharmaceutical Sciences students
Learn to program, gain knowledge of AI methods, or use it in a research project at the LACDR. With the introduction of the innovative digital learning environment ‘Digital Labcoat’, Biopharmaceutical Sciences bachelor students can further develop their computational skills.
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Developing drugs with artificial intelligence
Developing new drugs is a difficult process. With the aid of artificial intelligence, Pharmaceutical scientist Xuhan Liu has developed methods that can help make drug design cheaper and faster. PhD defence on 15 February.
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Successful symposium on Circuit Topology
On the 8th of December 2021, Leiden Academic Centre for Drug Research (LACDR) organized “Circuit Topology 2021”, the first international symposium on circuit topology. The focus was on the mathematical notion of Circuit Topology, and its applications to physics, chemistry and biomedicine.
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Stiffness and viscosity of cells differ in cancer and other diseases
During illness, the stiffness or viscosity of cells can change. Tom Evers demonstrated this by measuring such properties of human immune cells for the first time. ‘The stiffness of certain cells could be a way to make a diagnosis,’ Evers said. He defended his thesis on March 26th.
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Gijs van der MarelFaculty of Science
marel_g@chem.leidenuniv.nl | +31 71 527 2727
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Peter ten DijkeFaculteit Geneeskunde
p.ten_dijke@lumc.nl | +31 71 526 9270
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Hendrikus TankeFaculteit Geneeskunde
h.j.tanke@lumc.nl | +31 71 526 9201
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Silvere van der MaarelFaculteit Geneeskunde
s.m.van_der_maarel@lumc.nl | +31 71 526 9480
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Akos KovácsFaculty of Science
a.t.kovacs@biology.leidenuniv.nl | 071 5274384
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Jitske van WelsenFaculty of Science
j.van.welsen@biology.leidenuniv.nl | 071 5272727
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With this algorithm, new medicines can be found more quickly
Did he dare take a gamble with his PhD research? Jeroen Methorst didn’t have to think long about it. It could fail or turn out very well. The latter is the case. Methorst developed a computer system that helps researchers find the protein they need. ‘Our whole group is now using this program.’ Methorst…
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Can Parkinson's be stopped by unravelling protein fibres? Anne Wentink finds out with a Vidi grant from NWO
In brain diseases such as Parkinson's and Alzheimer's, proteins clump together to form fibres. ‘Chaperone proteins’ unravel those fibres, but in the test tube biochemist Anne Wentink saw that this can also cause new problems. She is going to find out what happens inside cells to determine what a drug…
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Making the invisible visible with ‘click chemistry’
Sander van Kasteren (Professor of Molecular Immunology) makes the invisible visible. He will explain more in his inaugural lecture.
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Superselective bonds light up
Rather than one key and one strong lock, biology often uses tens or hundreds of weaker links to bind parts together, such as cells membranes. This allows for selectivity and also reversibility: the binding can also be undone. Researchers first caught this phenomenon using spheres or colloids, and published…
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Madouc Bergers made her own enzyme inhibitors for her bachelor’s thesis
For her bachelor’s thesis, Molecular Science and Technology student Madouc Bergers synthesized her own molecule that can inhibit the breakdown of sugars. Although most students do not even manage to make one building block, Madouc made three. Partly because of this, she has been nominated for the Science…
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Smart programming for the quantum computer that does not exist yet
Designing innovative algorithms, thinking outside the box, and brainstorming over coffee with his colleagues — this is what physicist Stefano Polla enjoys most. His success shines through in his nomination for the C.J. Kok Jury Award 2024 for PhD thesis of the Year.
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Environmental awareness at work
The University has ambitious plans for reducing the environmental impact of its activities. To this end we have taken university-wide measures in the form of improved building sustainability, sustainable energy and water-saving measures. As an employee, you can also contribute to lowering the environmental…
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Kilometre allowance
For your commuting days, you can apply for a supplementary kilometre allowance in the Terms of Employment Individual Choices Model. You will not be reimbursed in full for your commuting expenses, but by offsetting your gross income, you will benefit from a tax benefit.
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Bilingualism
The University aims to be bilingual, and provides its information in Dutch and English wherever possible. This has consequences for the information provided on the University websites.
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Living at the Leiden Bio Science Park? Apply for an apartment
Organisation
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Dissertation layout requirements
The layout of a dissertation must meet certain requirements. Special rules also apply if the dissertation was written with others or if a commercial edition will be published.
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Email
Do you want access to your mailbox via your webmail? Do you want to share a single e-mail address with a number of colleagues? Read about the different options for email.
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Optimizing Solvers for Real-World Expensive Black-Box Optimization with Applications in Vehicle Design
PhD defence
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University to switch from SAP to Vidatum for research time tracking
Research
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From classroom to coastline: Nature-based learning in Honours College
In the Honours College course 'Climate, Sustainability and Wellbeing', students do more than just sit in a lecture hall. They are encouraged to explore climate and sustainability topics by connecting them to personal, embodied experiences and the natural world.
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Zware metalen hebben slechte reputatie, maar genezen ook kanker
Veel mensen denken dat zware metalen giftig zijn en mens en natuur altijd schade aanbrengen. Dat beeld moet genuanceerd worden, vindt hoogleraar Sylvestre Bonnet.
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Artificial intelligence as the co-pilot for drug discovery
There are more molecules that could conceivably be candidate drugs than there are stars in the universe. How can we ever efficiently identify those molecules? Professor of AI and Medicinal Chemistry, Gerard van Westen: ‘I’m going to use artificial intelligence as the co-pilot to make an automated search.’…
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Finally solved: how the body's own marijuana spreads through the brain
Since its discovery thirty years ago, it remained a mystery: how does the body’s own marijuana move between nerve cells in the brain? Mario van der Stelt and his research group have now uncovered the answer. This insight could aid the development of new treatments for pain and neurological disorders…
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Interdisciplinary Collaboration Explores Substance P in Health and Disease
A team of LACDR scientists from three different divisions (SPP, BT, MC) contributed to a book on "Substance P in Health and Disease," which will be published by Elsevier. The project was a collaboration with Hannover Medical School (Germany) and was coordinated by Alireza Mashaghi. Master students Ehsan…
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Flu stops when you block the enzyme that cleaves off virus particles
A flu virus could cause a pandemic. And then we would be poorly armed because flu viruses are starting to become resistant to flu medications like Tamiflu. Chemist Merijn Vriends successfully worked on an improved version of such medications. He will be awarded his doctorate on September 12th.
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In memoriam Harold V.J. Linnartz 1965 – 2023: Unlocking the Chemistry of the Heavens
With great sadness we share the news that Prof. Harold Linnartz passed away suddenly and unexpectedly on Sunday 31 December 2023. We are all in shock, and our thoughts are with his wife and children, other family, and friends. Harold was at the heart of our institute, as a researcher, as a supervisor,…
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Thirteen NWO Open Competition XS grants for Leiden researchers
From medicines from snake venom to supercrops and the origin of words. Thirteen researchers from Leiden University will receive Open Competition XS grants from the Dutch Research Council (NWO).
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Countering nerve pain caused by chemotherapy with new drug
Nerve pain is one of the most common side effects of chemotherapy. It is therefore one of the biggest reasons for cancer patients to stop treatment early. Darcy Reynolds worked on new drug candidates against this pain during her bachelor's thesis. She developed a new series of molecules that increase…
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From collagen to canvas: interactive artwork brings the world between our cells to life
What’s really happening in the space between the cells in your body? With the Collagen Canvas project, students from Leiden University invite you to explore this question by blending science with art. This interactive artwork immerses you in the dynamics of the extracellular matrix—the invisible structure…
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Antibiotic resistance: an economic problem universities could help to solve
Antibiotic resistance is an economic problem. Pharmaceutical companies cannot earn much from antibiotic research, so they do not invest in it. This makes it important that universities do so, says Ned Buijs.
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Webb reveals chemical profile of atmosphere of exoplanet WASP-39 b
An international team of astronomers has revealed the first 'chemical profile' of an exoplanet's atmosphere. The team, including Leiden astronomer Yamila Miguel and provenda Amy Louca, made the profile using so-called Early Release Science data from the James Webb Space Telescope. The results have been…
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How to hijack natural destruction in cells: ‘We need to understand it through and through’
Destroying proteins from the Golgi apparatus of the cell in a controlled manner. That is the focus of chemist Marta Artola’s pioneering research. By developing a groundbreaking technology to target specific proteins in the Golgi, Artola aims to unlock new ways for drug development. For this ambitious…
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From bachelor student to entrepreneur: card game about elementary particles an unexpected hit
bachelorstudent Serafine Beugelink ontwikkelt kaartspel over elementaire deeltjes en deeltjesfysica. Ze zet succescol haar eigen bedrijf op.
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Recent PhD defenses
Here we highlight the achievements of our latest PhD graduates, each of whom has made significant contributions to the advancement of the field of (bio)pharmaceutical sciences.
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A smarter way to search for antibiotics
Bacteria carry countless hidden treasures in their DNA: fragments that could hold the key to new medicines. But how do you pick out the most promising ones from millions of options? ‘Look at the switches that turn genes on and off,’ says molecular biologist Gilles van Wezel.
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Webb detects icy ingredients for making potential habitable worlds
An international team of astronomers, led by Will Rocha of Leiden Observatory, using the NASA/ESA/CSA James Webb Space Telescope have discovered that the key ingredients for making potentially habitable worlds are present in early-stage protostars, where planets have not yet formed.