671 search results for “single molecule biophysics” in the Staff website
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This is how physicists use light to build complex structures
Petr Steindl works on quantum dots in microcavities for his PhD research. He manipulates single-photons to create complex structures of light. Applications could include quantum communication and gates for quantum computers.
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Planet-forming discs around young low-mass star differs fundamentally from one around sun-like star
Using the James Webb Space Telescope, an international team of researchers, including Leiden Professor of Molecular Astrophysics Ewine van Dishoeck, has discovered a palette of hydrocarbons in a planet-forming disc around a young, low-mass star. The results confirm that discs around very lightweight…
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Leiden-developed drug candidate ready for final clinical trial phase
Bringing your drug candidates to patients is what many academic chemists dream about, but the road to this goal is long and bumpy. Now, Leiden small molecule nizubaglustat is ready for phase 3 clinical trials. This is thanks to a €132 million funding secured by the biotech spin-out Azafaros.
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Huub de GrootFaculty of Science
h.j.m.de.groot@lic.leidenuniv.nl | 071 5274539
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Dag van de duurzaamheid: Launch Billiecup
Op de dag van de duurzaamheid van 10 oktober startte de 'Billiecup' pre-pilot op de Faculteit der Rechtsgeleerdheid. Aanwezig waren 'plastic soup surfer' Merijn Tinga, Bart Hemmes van het Leiden University Green Office (LUGO) en Esther Kentin, docent bij instituut Metajuridica & projectleider Leiden…
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Active Learning Classrooms
If you want your students to be actively involved in your lecture or tutorial, book an Active Learning Classroom!
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About BAS InSite
Starting in January 2026, Leiden University will transition to a new, future-proof software system: BAS InSite. This system will replace SAP Self Service and handle personnel, financial, and administrative matters currently managed through the Serviceplein.
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Bound for Devotion: The Prayer Book as Object and Practice, 1300–1800
Conference
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Innovation and grants
If you’re inspired to introduce innovations or have plans to update a course or learning pathway, the tips and starting points given here may be helpful.
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Phishing
We all occasionally receive an email from an unknown sender, with content we weren’t expecting or that raises our suspicions in some other way. This is usually a fake email, also known as a phishing email. In fact, there are various types of phishing: it can also be done over the phone.
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Hybrid teaching
Hybrid teaching combines face-to-face teaching on campus with online attendance: some students are present in class, while others join remotely at the same time via a livestream.
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In the end, we all want the same thing: to be a strong, inspiring, and compassionate institute
On Monday 3 November, Hanneke Hulst bid farewell to the Institute of Psychology and gave a heart-warming speech to her colleagues. After two years as scientific director, she is moving to New Zealand to start a new chapter in her life. ‘I wish you all one thing that costs nothing but is worth everything:…
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Can birds imitate R2-D2? Yes – and some are surprisingly good at it
Scientists have discovered that starlings and parrots can imitate the complex sounds of Star Wars droid R2-D2 remarkably well. Their study reveals how the structure of a bird’s vocal organ determines its vocal abilities – and how citizen science helps uncover it.
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Women in early modern courtrooms: 'A cross-section of society'
In early modern England, courts of law were working overtime. University lecturer Lotte Fikkers delved into the records of centuries-old court cases involving women. In Early Modern Women's Life-Writing and English Law, she reconstructs how the story they told in court differs from the one they wrote…
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Improving nature’s antibiotic
'What nature made isn’t necessarily an optimized medicine to use in the human body,’ says Professor of Biological Chemistry Nathaniel Martin. That’s why a group of Leiden researchers is making a chemistry-based improved version of the frequently used antibiotic vancomycin. They received an NWO NACTAR…
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Astronomers spot benzene in planet-forming disk around star for first time
An international team of astronomers including Leiden professor Ewine van Dishoeck has observed the benzene molecule (C6H6) in a planet-forming disk around a young star for the first time. The observations tell us more about the forming of planets in this disc, like our own Earth. The scientists publish…
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Chemotherapy without side effects? It’s possible, with light
Nausea, neurologic pain and hair loss: some of the severe side effects of chemotherapy. Not necessary, biochemist Liyan Zhang showed. Together with Leiden biologists and others, she achieved great results with a drug that is only active in combination with light. Zhang will defend her PhD on 4 July.
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The Nobel Prize in Chemistry went to an AI model (and rightly so)
Not experiments and lab coats, but computers and artificial intelligence: this year's Nobel Prize in Chemistry went to the inventors of the groundbreaking AI model, AlphaFold. This programme accurately predicts protein structures based on their genetic code—a crucial step in understanding biological…
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Frequently asked questions
You can find here questions and answers about the new mobility policy and what this means for the commuting allowance, the home-working allowance, the contribution to internet use, domestic business travel and the kilometre allowance via the Individual Choices Model.
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How cells talk by pulling on a fibre network
Mechanics play a larger role in blood vessel formation, and other developmental biology, than previously thought. Cells appear to respond to mechanical signals, such as pressure. Through the extracellular matrix, a network of fibrous proteins, cells can supposedly exchange those mechanical signals over…
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Newly discovered enzyme could play crucial role in bacterial breakdown of plastics
Leiden researchers have discovered an enzyme that helps bacteria feed on everyday plastics. This common enzyme could play a crucial role in future research and eventually in addressing the global plastic crisis. The study was published in Nature Communications.
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Medical Delta AI for Computational Life Sciences
The fact that scientists are increasingly better able to access molecular cell and tissue data also brings with it a new challenge: how can scientists find the information they need for research among the vast amount of data available?
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Ewine van Dishoeck receives Fritz Zwicky prize for astrophysics & cosmology
The Fritz Zwicky Prize 2022 for Astrophysics & Cosmology has been awarded to Prof. Ewine F. van Dishoeck for her pioneering, decades-long work in astrochemistry and molecular spectroscopy, as well as for her leadership within the astronomical community. The award was announced today by the European…
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A foldable smartphone? STIBNITE searched for the perfect semiconductor
Roll-up solar panels, bendable phone displays, or better computer chips… The EU project STIBNITE investigated the next generation of semiconductors, made from organic materials based on carbon, nitrogen, and boron. The project has now concluded. During the Open Science Debate on 1 July, the group will…
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How a pathogenic bacterium searches for food
Bacteria whirl around in the mouths of most people, forming dental plaques and sometimes causing nasty gum infections. Treponema denticola might be a dangerous pathogen, but not much is known about this bacterium. It was up to Ariane Briegel and her research group to change that.
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Oncode Accelerator launched: patients at the centre of innovative cancer drug development
Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process.
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How bittersweet sugar chemistry targets pathogens
The challenge is considerable, but so is the satisfaction when it succeeds: creating complex sugar molecules that play a role in biology.
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Investigating inflammation: new leads for treating atherosclerosis
How do you detect people at high risk of heart attacks and strokes? And how can we improve the treatment of atherosclerosis? These are the questions that keep LACDR researcher Marie Depuydt busy. She is investigating the immune cells that contribute to the worsening of atherosclerosis. ‘It's a challenging…
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Three NWO Open Competition grants for Leiden scientists
Smart drug carriers, uneven cosmic expansion, and solar energy storage in molecules. These are the topics of three newly awarded NWO-XS grants to researchers at the Faculty of Science.
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More efforts for less waste: reusable crockery will become standard
Facility
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Perpetuating Highland Heritages of Bhutan
Jelle Wouters (RTC Bhutan), Erik de Maaker (CADS Leiden) and Radhika Gupta (CADS Leiden) have been awarded a €260.000 grant by the Gerda Henkel Foundation for the research project ‘Perpetuating Highland Heritages of Bhutan’. This 4-year research project focuses on vernacular and unacknowledged heritages…
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Best poster presentation award for Jill de Mol at the GEMseq 2024 meeting
During the 6th edition of the Graz Expert Meeting on Single-cell sequencing technologies in the cardiovascular field, held on September 15 and 16 in Graz, Austria, Jill de Mol from the group of Dr. Amanda Foks from the Division of BioTherapeutics received the award for best poster presentation.
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Man-made antibodies may change the future of drug development – here’s why
Sometimes an idea seems so logical and elegant at first glance, that you later wonder why no one thought of it before. Two researchers from LACDR have teamed up to develop a completely synthetic alternative to antibodies—one that mimics their size, shape and function, but which is cheaper, more stable,…
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Status update in the evolutionary race between humans and resistant bacteria: two steps forward for us
A patent for what may be a potent, new antibiotic. And: a clear overview of promising approaches to overcome a crucial resistance tactic employed by bacteria. In the span of one week, two researchers from Leiden are receiving their PhDs, each of them on an important step in the battle against bacteria…
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Rubicon grant for Remko Fermin: superconducting diodes for energy-efficient data centres
Physicist Remko Fermin from Leiden University was awarded a Rubicon grant from NWO. He will use it to study superconducting diodes that could contribute to reducing the CO2 emission of data centres.
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Sugar chemistry – Wouter Remmerswaal’s unrelenting pursuit of understanding
The dark matter of biology: clumps of sugar molecules that, for example, form sugary webs around pathogens. We know very little about them. Wouter Remmerswaal threw all his talent into the challenge – both in the lab and as a modeller – and succeeded. He received his PhD on 12th September.
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Frits RosendaalFaculteit Geneeskunde
f.r.rosendaal@lumc.nl | +31 71 526 4037
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Adam CohenFaculteit Geneeskunde
ac@chdr.nl | 071 5269111
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Ferry OssendorpFaculteit Geneeskunde
f.a.ossendorp@lumc.nl | +31 71 526 3800
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Marcellus UbbinkFaculty of Science
m.ubbink@chem.leidenuniv.nl | +31 71 527 4628
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Thomas HankemeierFaculty of Science
hankemeier@lacdr.leidenuniv.nl | +31 71 527 4226
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Marcel TijstermanFaculteit Geneeskunde
m.tijsterman@lumc.nl | +31 71 526 9111
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Henk-Jan GuchelaarFaculty of Science
h.j.guchelaar@lumc.nl | +31 71 526 2790
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Professor Ewine van Dishoeck named Citation Laureate
Emeritus Professor of Molecular Astrophysics Ewine van Dishoeck has been named a Citation Laureate by Clarivate, a research analytics provider. Clarivate considers her an influential researcher of the calibre to win a Nobel Prize.
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What if superbugs were as tall as buildings?
In Sci-Fi comic book Resist NOW!, wondrous adventures will illustrate possibilities to combat antimicrobial resistance. But the comic book will only be produced if enough money is raised to make the project into reality.
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Local residents research their own problems
The Countering Syndemic Vulnerability project supports communities by identifying and tackling clusters of social factors and health problems. The project works with residents and professionals in the Moerwijk district in The Hague and the Stevenshof district in Leiden.
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Synthetic Miniproteins Enter the Fight Against MYC-Driven Cancers
The transcription factor MYC is a master regulator implicated in the majority of human cancers. Despite its central role, MYC has long been considered "undruggable" by small molecules, lacking binding pockets and featuring disordered regions. While larger biomolecules could potentially disrupt MYC function,…
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Daan Jiskoot wins the Suzanne Hovinga Award 2024
During the LACDR Fall Symposium, Daan Jiskoot received the annual Suzanne Hovinga Award for the best master thesis. Daan performed his Research Project 2 at the University of California, Irvine at the Prof. David Mobley lab, supported by LACDR supervisor Willem Jespers. The in silico determination of…
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Special telescope measures neutrino with highest energy ever
Even with state-of-the-art technology, it is almost impossible to see: a cosmic neutrino. Yet scientists have managed to image this particle with a deep-sea telescope. And that could help to better understand our universe. Leiden particle physicists collaborated on this ambitious project, published…
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€10.6 million for innovative toolboxes to tackle brain cancer
Researchers at the Universities of Amsterdam (Uva) and Leiden together with the Netherlands Cancer Institute and Oncode Institute have received a €10,6 million ERC Synergy Grant to develop innovative therapeutic approaches to target glioblastoma. This is a deadly primary brain tumour for which no curing…