The guardian of our genome, the protein MutS, scans the DNA for spelling errors and makes sure they are corrected. An essential process for our health. Researchers at Leiden University Medical Centre (LUMC) have discovered precisely how this protein works by making MutS visible with cryo-electron microscopy.…

BRAIN Biotech and the Leiden University will jointly develop an Aspergillus based production strain with high yield and thus contribute to a bio-based circular economy. The cooperation is based on BRAIN´s molecular tool BEC.

Prof Dr Joke Bouwstra will receive the “ Dr Saal van Zwanenberg Ereprijs” from the “Koninklijke Hollandse Maatschappij der Wetenschappen” on November 14 in Haarlem. Joke is awarded for her innovative contributions to the field of skin delivery science and technology. She shares the price with prof…

Two Leiden researchers have been awarded ERC Proof of Concept grants. These grants, each worth EUR 150,000, will help the grantees in their efforts to bridge the gap from basic science to real-life applications

Imagine scanning lion dung or a mouse dropping and instantly knowing exactly what and how much the animal has eaten. Thanks to new DNA techniques, this is becoming increasingly feasible. PhD student Kevin Groen tested how effective these techniques are at unraveling the diets of wild animals.

To eat or get eaten. It describes the evolutionary race of snakes versus the mammals and birds that prey on these snakes. Muzaffar Ali Khan devoted his PhD to investigating the molecular mechanisms play of the evolutionary arms race, and has his promotion 16 February. What makes mammals and birds successful…

Sander van Kasteren (Professor of Molecular Immunology) makes the invisible visible. He will explain more in his inaugural lecture.

Sometimes an idea seems so logical and elegant at first glance, that you later wonder why no one thought of it before. Two researchers from LACDR have teamed up to develop a completely synthetic alternative to antibodies—one that mimics their size, shape and function, but which is cheaper, more stable,…

Seven Leiden professors have been elected as members of the Royal Netherlands Academy of Arts and Sciences (KNAW). In total 23 new members will be inaugurated on Monday 13 September.

For over a year now, the James Webb Telescope has been sending stunning images that exceed astronomers’ expectations. The photos are fascinating to see, but what exactly are we looking at? Assistant professor Melissa McClure explains.

How do you fulfill a chairing position during a team meeting? How do you visualise a dataset for a presentation? How do you write the introduction to a scientific article? All Science students can find the answers to these and many more questions in the 100+ skill modules on the digital Science Skills…

Luc Amkreutz, curator of prehistory at the National Museum of Antiquities in Leiden and professor of Public Archaeology at Leiden University, has a mission: to make the past accessible and relevant to a broad audience. He is the new Eugène Dubois Visiting Professor at the Faculty of Science and Engineering…

Emeritus Professor of Molecular Astrophysics Ewine van Dishoeck has been named a Citation Laureate by Clarivate, a research analytics provider. Clarivate considers her an influential researcher of the calibre to win a Nobel Prize.

During the LACDR Fall Symposium, Niek Kijk in de Vegte received the annual Suzanne Hovinga Award for the best master thesis. Niek performed his RP1 research under the supervision of Dr. Natalia Ortiz Zacarias and Prof.dr. Laura Heitman in the Molecular Pharmacology group at the Division of Drug Discovery…

During the LACDR Fall Symposium, Daan Jiskoot received the annual Suzanne Hovinga Award for the best master thesis. Daan performed his Research Project 2 at the University of California, Irvine at the Prof. David Mobley lab, supported by LACDR supervisor Willem Jespers. The in silico determination of…

Yeast, alpacas, and antibodies. They may seem unrelated, but within the project of the Leiden iGEM students, they come together perfectly. For the international synthetic biology competition iGEM, the team is working on an innovative method to produce nanobodies—a special form of antibodies—using brewer’s…

What started as an idea during a social gathering led to an unexpected breakthrough in research on resistant bacteria. Biologists and chemists from Leiden developed a new substance that proves to be effective against bacteria resistant to antibiotics. They published their discovery in Nature Chemist…

‘’ And then the world changed forever ,welcome to the future’’. These are the words that Kausik Ray (President of the European Atherosclerosis Society) spoke when the worldwide first dose of inclisiran, a novel SiRNA based cholesterol lowering agent, was administered at the Cardiology lipid clinic at…

Plant biologist Pingtao Ding, assistant professor at the Institute of Biology Leiden (IBL), has received a 2.4 million European grant from the European Research Council (ERC). This ERC Starting Grant for promising young researchers allows him to unravel the molecular mechanisms by which plants resist…

The Fritz Zwicky Prize 2022 for Astrophysics & Cosmology has been awarded to Prof. Ewine F. van Dishoeck for her pioneering, decades-long work in astrochemistry and molecular spectroscopy, as well as for her leadership within the astronomical community. The award was announced today by the European…

With the aid of physics and a minuscule magnet, researchers have discovered a new structure of telomeric DNA. Telomeres are sometimes seen as the key to living longer. They protect genes from damage but get a bit shorter each time a cell divides. If they become too short, the cell dies. The new discovery…

How do you engage students? Sander van Kasteren knows how to do that like no other. ‘He compares immune cells to Pokémon and doesn’t just give information; he tells stories,’ students say about their favourite lecturer, Sander van Kasteren. The Professor of Molecular Immunology passionately teaches…

Smart drug carriers, uneven cosmic expansion, and solar energy storage in molecules. These are the topics of three newly awarded NWO-XS grants to researchers at the Faculty of Science.

One of our RISE members, Prof. Laura Heitman, has been nominated for the TOPX Females to Follow “Guiding Star” award. TOPX empowers promising and ambitious women, and aims to honour inspirational females with remarkable careers in Life Sciences. TOPX selected her (and 7 other female professionals) because…

From 1 October, two new Directors of Education will start at the Institute of Biology Leiden (IBL). Dennis Claessen as the new director for the master's programme of Biology and Marcel Schaaf as director for the Biology bachelor's programme. Claessen and Schaaf have been appointed for a period of four…

For the second year in a row, LACDR organized an international symposium on molecular fold topology. An afternoon program centered around the theme “circuit topology”, inspired and connected mathematicians, physicists and chemists. Scientists from USA, Europe, and Asia participated in this online ev…

As many as seven first-year students from the Faculty of Science were honoured as young talents. In addition, the Royal Holland Society of Sciences and Humanities (KHMW) also lauded three master's students and an astronomy project during a vibrant ceremony on 28 November. Professor of Science Communication…

Each year, CML gives out three Stans Awards. The Institute's staff could nominate students and colleagues for the prices of best student thesis, best PhD paper and best outreach from the past year. Jury members Jan Willem Erisman and Nicole de Voogd made the final decision.

The fastest chemical reaction in the universe takes place inside our eyes.

Two research groups involving Leiden University have been awarded a major European grant, the ERC Synergy Grant. This for research on the development of membranes that can clean water and purify medical drugs and research on the biological clock in certain bacteria.

As of this month, Kim Bonger has been appointed Professor of Chemical Biology. As a first-generation academic, she’s especially grateful. ‘I wasn’t exactly a top student at school. I never could’ve imagined this.’

Roll-up solar panels, bendable phone displays, or better computer chips… The EU project STIBNITE investigated the next generation of semiconductors, made from organic materials based on carbon, nitrogen, and boron. The project has now concluded. During the Open Science Debate on 1 July, the group will…

What happens in the brains of people with psychiatric illnesses? With a €23.23 million gravity grant, scientists from different fields will search for biological causes over the next decade. ‘By joining forces, we hope to improve diagnosis and treatment for patients with these diseases.’

Is it a coincidence that three chemists from the same department have each independently received a ZonMw grant? 'No,' the researchers agree in unison. 'The role of chemistry in medical biology is becoming increasingly important, and we’ve worked hard to make this happen.'

On the 6th and 7th of September 2023, the Leiden Academic Centre for Drug Research (LACDR) organized the Leiden Bio-AFM workshop in cooperation with Bruker Nano GmbH (Germany) and Bruker Nederland BV. The organization of this event was led by the Medical Systems Biophysics and Bioengineering group (Alireza…

The Rob Schilperoort Memorial will be unveiled at the Leiden Bio Science Park on Saturday 16 September. This gigantic gate stands at the entrance to the park, which is also named after Schilperoort, its founder.

The 'deepest and sharpest' image of the Universe to date: the first photos from the new James Webb space telescope yesterday mesmerised astronomers and the public alike. Leiden Professor of Molecular Astrophysics, Ewine van Dishoeck, spoke to various media outlets about the first images, which include…

As of 1 September, Marco van Eijk has been appointed Director of Education of the bachelor's programme Life Science & Technology. He succeeds Marcellus Ubbink, who moved to the position of Scientific Director of the Leiden Institute for Chemical Research (LIC). Van Eijk has been appointed for a period…

On Tuesday evening 22 August, our very dear colleague Jo Hermans passed away. Jo had been ill for some time, but continued to enjoy life in good spirits until the very end. He meant a great deal to Leiden University and will be remembered with fond memories by many.

PhD defence

Conference

PhD defence

Bacteria carry countless hidden treasures in their DNA: fragments that could hold the key to new medicines. But how do you pick out the most promising ones from millions of options? ‘Look at the switches that turn genes on and off,’ says molecular biologist Gilles van Wezel.