A microscope with incredible sharpness that leaves samples unharmed – Guido Stam helped develop one. During his PhD research, he combined light and electrons to study biological samples. ‘We can now measure things that simply weren’t possible before.’

In addition to cholesterol and high blood pressure as risk factors for atherosclerosis, we may need to address our own immune system to prevent a heart attack or stroke. Marie Depuydt revealed which cells exactly reside in the atherosclerotic plaque that narrows an artery. The presence of a diverse…

A flu virus could cause a pandemic. And then we would be poorly armed because flu viruses are starting to become resistant to flu medications like Tamiflu. Chemist Merijn Vriends successfully worked on an improved version of such medications. He will be awarded his doctorate on September 12th.

Bacteria carry countless hidden treasures in their DNA: fragments that could hold the key to new medicines. But how do you pick out the most promising ones from millions of options? ‘Look at the switches that turn genes on and off,’ says molecular biologist Gilles van Wezel.

A true shower of awards for students from the Faculty of Science during the annual KHMW Young Talent Awards ceremony. On Monday, 25 November, no less than nine first-year students received a prize for the best academic results in their first year. In addition, there were graduation prizes for master’s…

Secret services are engaging in increasingly extreme forms of cyber espionage. But nobody talks about this. Dennis Broeders knows why and is trying to have an open conversation about new forms of espionage. As Professor of Global Security and Technology, he will give his inaugural lecture on Friday…

For the first time, it was shown in living cells how the bacterium E. coli regulates genes that help it survive in a new environment. Biochemist Fatema Zahra Rashid managed to do this using a technique she fine-tuned. Her research into changes in 3-dimensional chromosome structure offers clues for ways…

Researchers from the Leiden University Medical Center (LUMC) have successfully used stem cell gene therapy to treat a baby with the severe congenital immune disorder SCID. An important milestone: it is the first time stem cell gene therapy of Dutch origin has been administered to a patient, and also…

In dermatology, there should be a high level of multidisciplinary collaboration among institutes and specialists, Professor of Translational Dermatology, Robert Rissmann, will say in his inaugural lecture on 8 July. He is building an infrastructure that will put pre-clinical and clinical skin research…

The LUMC has become the first institution in the Netherlands to treat a patient with an autoimmune disease using CAR T-cell therapy.

Immunologist Leender Trouw specialises in the complement system, which is part of the immune system. In some diseases drugs help activate or inhibit this system. This is best done ‘in the right place at the right time’ − the title of his inaugural lecture.

How safe are the dozens of apps on our phone? And how do we make sure organisations don’t get hacked? Cybersecurity expert Olga Gadyatskaya works on all these kind of security issues. Next to that, she hopes to inspire young girls to consider a career in cybersecurity. ‘Too many young women think: I’m…

Why does a medicine work well for one person, but cause side effects in another? Research by Laura de Jong shows that it’s not just our DNA that matters – other medicines and illnesses can also affect how our bodies respond.

Whether a microbe is beneficial or harmful to a plant can now be predicted with high accuracy thanks to bacLIFE. This bioinformatic tool with an intuitive interface makes it much easier to unlock the secrets of bacterial genomes. A group of Leiden biologists presented it in Nature Communications.

Dario Fazzi works at the Institute for History as Assistant Professor. Although he's not not completely new to the Institute, he recently received a permanent appointment. Below he introduces himself!

How does the soil we grow our vegetables in, affects the health of our gut? And does a healthy soil gives crops a better quality and taste? These are some of the questions Soil ecologist Emilia Hannula and a big consortium will work on. With an NWO-KIC grant of 1.8 million, CML, IBL, FGGA, the LUMC,…

A patent for what may be a potent, new antibiotic. And: a clear overview of promising approaches to overcome a crucial resistance tactic employed by bacteria. In the span of one week, two researchers from Leiden are receiving their PhDs, each of them on an important step in the battle against bacteria…

Does medicine make patients feel better or worse? We are getting better at predicting this from people’s DNA profiles, says Professor Jesse Swen. ‘It never fails to fascinate me how one DNA base pair can have such a huge effect on treatment with medication and the outcome.’

PhD defence

‘Men must make way. GroenLinks–PvdA voters are sending at least three additional women into the House of Representatives through preferential votes,’ Trouw headlined this week. What would happen if we allocated all seats on the basis of preferential votes? And would we see differences between the pa…

Eighteen researchers from Leiden University have been awarded a Veni grant by the Dutch Research Council (NWO). This grant gives promising young researchers the opportunity to develop their ideas for a period of three years.

Lecture, Pint of Science

Photographing fluorescent flowers, searching for frogs and shooting tropical cucumbers out of trees: this is only a small part of the course Tropical Biodiversity and Field Methods. For this class, master’s students biology traveled to Malaysian Borneo for two weeks to gain experience in fieldwork.…

The outbreak of coronavirus has radically changed our life and work. We have had to work, teach and conduct research from home. How has coronavirus changed your work? What do you miss most? And what is keeping you going? We asked a few colleagues.

Two deans: one leaving and one just arriving. Paul Wouters was deputising at the Faculty from March up to December. As of January he returns to his 'ordinary' role as dean of the Faculty of Social Sciences. Jasper Knoester is taking over from him, as he will be leaving Groningen for Leiden. How did…

Hit the brakes! That’s the advice of the Council for Public Health and Society in a recent report. Eight psychologists share their insights on how to slow down and reconnect.

The airspace had almost closed last year as Leiden students and staff rushed to leave the Netherlands Institute Morocco (NIMAR). How is this Leiden institute in Rabat doing over a year later? ‘Luckily we’d done a crisis exercise a few months before. Everyone managed leave the country in time.’