Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.

Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska

This dissertation combines the use of defined microenvironments, high-resolution fluorescence microscopy, and time-resolved analysis, to study intracellular and cellular motility.

Promotor: T. Schmidt, Co-Promotor: B.E. Snaar-Jagalska

This thesis tackles the difficulty of predicting the liver’s clinical response to novel therapies, a challenge arising from interspecies differences and limitations of existing in vitro models.

Prostate cancer (PCa) is one of the most prevalent cancer in males.

Promotor: J.A. Bouwstra Co-promotor: A. El Ghalbzouri

G protein-coupled receptors (GPCRs), one of the largest families of membrane proteins, are responsive to a diverse set of physiological endogenous ligands including hormones and neurotransmitters.

PhD defence

PhD defence

PhD defence

Microbial rhodopsins are photosensitive pigments implemented in the growth and adaptation of a large population of microorganisms.

In this research project, we aimed to obtain more insight in the role of mast cells in the immune driven disorders rheumatoid arthritis and atherosclerosis.

Enabling volume-restricted metabolomics using next-generation microscale analytical tools.

Can Cyanobacteria be engineered to convert the greenhouse gas carbon dioxide into the valuable chemical isoprene?

Plants, algae and cyanobacteria have the amazing capacity to perform delicate photophysical and photochemical processes of light capture, excitation transfer, charge separation and catalysis in fluctuating living environments. As a consequence, photosynthetic proteins and membranes form dynamic architectures.…

Systems are called real-time systems, if the correctness of the system does not only depend on the correctness of the system output but also on whether the output is delivered on time.

2026

Research question

Contemporary Maya Calendars

The opening times of the Humanities buildings vary. The Lipsius building is opened during evenings as well, the other faculty buildings retain office hours.

Discover the power of interdisciplinary AI research at Leiden University's SAILS Initiative through this bi-weekly seminar. The SAILS network of AI experts spans all seven faculties: Law, Science, Archaeology, Social Sciences, Humanities, Governance and Global Affairs, and the Leiden University Medical…

With tomography it is possible to reconstruct the interior of an object without destroying.

A study concerning the collective memory in the region of the Bene lo Ya/ Ene lo I'ya, Sierra Norte, Oaxaca.

PhD defence

PhD defence

This thesis explored the molecular pharmacological mechanisms of targeting CB2R via investigation of novel drug discovery concepts such as target binding kinetics, allosteric modulation and biased signaling.

Understanding the temporal modes of digital mapping.

Predictive maintenance (PdM) is a maintenance policy that uses the past, current, and prognosticated health condition of an asset to predict when timely maintenance should occur.

Mining time series is a machine learning subfield that focuses on a particular data structure, where variables are measured over (short or long) periods of time.

This research hopes to contribute to social awareness of the consequences of colonialism for Indigenous Peoples, to the deconstruction of still existing colonial and discriminatory notions and to a better appreciation of Indigenous art and thought.

Increased public trust in law, government and democracy.

The group of Dr. Roxanne Kieltyka designs and synthesizes molecules that self-assemble into polymeric materials using specific non-covalent interactions. These substrates can be used for numerous applications in medicine ranging from disease detection to cell delivery depending on the (bio)molecular…

The Immune Activation and Tolerance group is headed by Dr. Bram Slütter. Vaccination is an experimental, but promising, treatment strategy for atherosclerosis. Previous work has shown that immunization of mice with modified LDL particles can reduce atherosclerotic lesion development, however such vaccines…

Promotor: Prof.dr. R. Verpoorte, Co-promotores: Dr. Y.H.Choi, N.R. Mustafa

Promotor: H.J. van den Herik, B.R. Katzy, Co-promotor: K. Sailer

The biweekly Lunch Time Seminar is an online only event, but it is not publicly accessible in real-time. If you would like to attend one of the upcoming sessions, please send an email to sails@liacs.leidenuniv.nl.

Lecture

Leiden Embedded & Real-time Computing (LERC) is an expert lab and leader in advanced research on embedded and real-time systems and software. The main mission of LERC is by its research to contribute in a highly innovative way to the system-level design of embedded and cyber-physical systems and software…

Lecture

This volume explores the nature of ellipsis, the core phenomenon that results in various types of omission in sentences.

Lecture

Lecture