1,129 search results for “optimize drug design” in the Staff website
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LACDR PhD Introductory course on Drug Research
This week, we had the LACDR PhD Introductory course on Drug. This is always a great opportunity for starting PhD candidates to get to know LACDR, CHDR, the Clinical Pharmacology department of LUMC and the embedding of the institute in the BioSciencepark as a whole.
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Growth Fund invests many millions in faster and more sustainable (cancer) drug development
On 14 April, the National Growth Fund awarded million euros in grants to two consortia in which Leiden's science faculty is involved. Pharma-NL will receive 80 million euros and Oncode-PACT 325 million euros. Pharma-NL wants to make medicines available to the patient faster and more sustainably. Oncode-PACT…
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Simulation of infant gut makes predictions about optimal milk
David Versluis successfully simulated an infant gut virtually. This is crucial for research on improvements in formula milk. Currently, such research primarily relies on diaper contents, which is not optimal. Versluis defended his doctoral thesis on April 23.
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Ben van WerkhovenFaculty of Science
b.van.werkhoven@liacs.leidenuniv.nl | 071 5272727
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Giulia CallegaroFaculty of Science
g.callegaro@lacdr.leidenuniv.nl | 071 5276105
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LACDR PhD introductory course on drug research
Due to the corona pandemic and the uncertainty of the circumstances end of January 2022, is decided to postpone the LACDR PhD introductory course.
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Leiden-developed drug candidate ready for final clinical trial phase
Bringing your drug candidates to patients is what many academic chemists dream about, but the road to this goal is long and bumpy. Now, Leiden small molecule nizubaglustat is ready for phase 3 clinical trials. This is thanks to a €132 million funding secured by the biotech spin-out Azafaros.
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Olivier BéquignonFaculty of Science
o.j.m.bequignon@lacdr.leidenuniv.nl | 071 5272727
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LACDR PhD Introductory course on Drug Research
The PhD introductory course will take place on 30 May, 31 May and 1 June 2022 in castle Oud Poelgeest. We are very happy that it will be a live event (as it stands now).
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Better ship designs thanks to smart algorithms
The perfect ship is light and sleek for speed, but also needs to be strong and stable for safe sailing. These and other conflicting requirements make it difficult, even with a supercomputer, to find the ideal design. Computer scientist Roy de Winter has developed an algorithm that helps strike the perfect…
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Marie-leen RyckaertFaculty of Governance and Global Affairs
m.l.e.ryckaert@fgga.leidenuniv.nl | 070 8009589
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New potential cancer drugs and where to find them
Cancer research generates massive amounts of data, but traditional tools often fail to fully harness their potential. How can we unlock this data to provide better treatments for cancer patients? PhD candidate Marina Gorostiola González explored this by using advanced data analysis techniques to guide…
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Willem Jespers appointed Assistant Professor AI & Structure Based Drug Discovery
Willem Jespers started his position as Assistant Professor in the group of Prof. G.J.P. van Westen on June 1st, a short introduction below:
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Joni ReefFaculteit der Rechtsgeleerdheid
j.reef@law.leidenuniv.nl | 071 5278596
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Countering nerve pain caused by chemotherapy with new drug
Nerve pain is one of the most common side effects of chemotherapy. It is therefore one of the biggest reasons for cancer patients to stop treatment early. Darcy Reynolds worked on new drug candidates against this pain during her bachelor's thesis. She developed a new series of molecules that increase…
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Guilherme PerinFaculty of Science
g.perin@liacs.leidenuniv.nl | 071 5272727
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Optimizing Solvers for Real-World Expensive Black-Box Optimization with Applications in Vehicle Design
PhD defence
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Bob van de WaterFaculty of Science
water_b@lacdr.leidenuniv.nl | 071 5276223
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How drugs work better when encapsulated in nanoparticles
Chemist Tobias Bauer discovered ways to improve drugs by encapsulating them. Packages with iron nanoparticles, for example, can stimulate immune cells. Bauer will receive his PhD on 9 June.
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LACDR launches training programme for innovative drug development
The Leiden Academic Centre for Drug Research (LACDR) has received a €750,000 grant from ZonMw for QPharmNL. This is a continuing education programme that trains professionals in computational techniques in pharmacology for innovative drug development.
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Eani LachmansinghFaculty of Science
e.t.lachmansingh@liacs.leidenuniv.nl | 071 5272727
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Mark RoelofsenFaculty of Governance and Global Affairs
m.roelofsen@fgga.leidenuniv.nl | 070 8009589
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Katja CardolFaculty of Social and Behavioural Sciences
c.k.cardol@fsw.leidenuniv.nl | 071 5275697
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Qinyu ChenFaculty of Science
q.chen@liacs.leidenuniv.nl | 071 5272727
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Julian SteinkeFaculty of Social and Behavioural Sciences
j.steinke@fsw.leidenuniv.nl | 071 5272727
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Sebastian Sewerin
Faculty of Social and Behavioural Sciences
s.sewerin@fsw.leidenuniv.nl | 070 8009500
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Niki van SteinFaculty of Science
n.van.stein@liacs.leidenuniv.nl | 071 5272727
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Alexander KrosFaculty of Science
a.kros@chem.leidenuniv.nl | 071 5274234
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Jiawen QiFaculty of Science
j.qi@liacs.leidenuniv.nl | 071 5272727
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Vasilii BokovFaculty of Science
v.bokov@liacs.leidenuniv.nl | 071 5272727
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Jana EnkingFaculty of Science
j.e.enking@cml.leidenuniv.nl | 071 5272727
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Bernhard SteubingFaculty of Science
b.r.p.steubing@cml.leidenuniv.nl | 071 5272727
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Kristian RietveldFaculty of Science
k.f.d.rietveld@liacs.leidenuniv.nl | 071 5277038
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How to choose the optimal location for wind turbines in the North Sea
In the next decades, thousands of wind turbines will be added to the North Sea. Environmental scientist Chen Li identified the most beneficial areas for their construction, focusing on material use, carbon footprint, and environmental impact. His paper was published in Environmental Science & Techno…
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for effective application of a new revolutionary cholesterol lowering drug resides in a 30 year old Leiden Patent
‘’ And then the world changed forever ,welcome to the future’’. These are the words that Kausik Ray (President of the European Atherosclerosis Society) spoke when the worldwide first dose of inclisiran, a novel SiRNA based cholesterol lowering agent, was administered at the Cardiology lipid clinic at…
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Review paper on the potential impact drug-metabolizing enzymes on brain exposure
PhD candidate Mengxu Zhang (Division of Systems Pharmacology and Pharmacy) published a comprehensive and important review on “The potential impact of CYP and UGT drug-metabolizing enzymes on brain target site drug exposure” in Drug Metabolism Reviews.
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Marieke Liem in The Economist on drug-related murders in Europe
Marieke Liem, professor at ISGA, discusses how the number of drug-related murders has not decreased in the last years
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Pregnant and drug dependent: Ministry of Justice tries to intervene with prosecution
Drug use during pregnancy seems like a choice without any consequences. However, the Dutch Public Prosecution Service (OM) has decided to prosecute a mother for using alcohol and drugs during her pregnancy. Mariëlle Bruning, Professor of Child Law, tells current affairs programme ‘Nieuwsuur’ that she…
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Universiteit Leiden Announce Collaboration to Develop Advanced Polyaminoacid Drug Delivery Systems
Polypeptide Therapeutic Solutions (PTS), a leader in the design, development and custom manufacturing of polyamino-acid based delivery systems for therapeutic drugs and the Leiden Academic Centre for Drug Research (LACDR) today announced a research collaboration to develop advanced drug delivery systems…
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Gerard van WestenFaculty of Science
gerard@lacdr.leidenuniv.nl | 071 5273511
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Executive Board visits Institute of Environmental Sciences: ‘Optimism-led solutions’
The Executive Board is visiting the university’s institutes to find out what is going on. On 8 July 2025, it was the turn of the Institute of Environmental Sciences (CML), one of the fastest-growing institutes at Leiden University. ‘Our main aim is to preserve our planet for future generations.’
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Duygu Uysal DincolFaculty of Social and Behavioural Sciences
d.m.uysal.dincol@fsw.leidenuniv.nl | 071 5272727
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Peter BerrillFaculty of Science
p.berrill@cml.leidenuniv.nl | 071 5272727
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Roozbeh SiyadatzadehFaculty of Science
s.r.siyadatzadeh@liacs.leidenuniv.nl | 071 5274799
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Major study offers practical guidance on antibiotic dosing in patients with obesity
Leiden researcher Anne-Grete Märtson brought together a large number of studies to better understand antibiotic dosing in patients with obesity. The publication in a renowned medical journal has already garnered much positive reactions, Märtson says. ‘It’s high time researchers started sharing more…
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Arteriosclerosis and drug discovery: two young researchers win Krijn Rietveld Award for innovative research
One discovered that arteriosclerosis resembles an autoimmune disease, while the other developed a system to aid in the search for new medications. For these achievements, Marie Depuydt and Jurren de Groot were awarded the Krijn Rietveld Memorial Innovation Award on the evening of Tuesday 4 June.
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Algorithm Design for Mixed-Integer Black-Box Optimization Problems with Uncertainty
PhD defence
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3 October University: from Russian DNA to drug-related violence
In prehistoric times there was a huge wave of migration, from the steppes in Russia and Ukraine to West Europe. The newcomers’ genes began to dominate. Archaeology research in Leiden into burial mounds in the Veluwe and Utrechtse Heuvelrug areas of the Netherlands yielded this spectacular conclusion.…
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Anita LiaoFaculty of Science
c.liao@lacdr.leidenuniv.nl | 071 5272727
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Dental remains shed light on drug use in 19th century Dutch village
Archaeologist Bjørn Peare Barthold suspected farmers in a doctorless 19th century Dutch village may have been self-medicating to manage pain and disease. By examining the skeletons' dental calculus this hypothesis could be tested. Science Magazine interviewed him about this new technique.