Promotor: K.E. Schalm, Co-promotor: S.S. Lee

The thesis describes terrestrial field trials aimed to detect side-effects of pesticides within the framework of pesticide registration procedures. Field trials were developed using vascular plants Brassica napus and Poa annua, caterpillars Pieris brassicae and effects on decomposition were studied…

This open access book brings together an eclectic cast of scholars in related disciplines to examine ageing in the Soviet Union, covering the practice of geriatrics, the science of gerontology, and the experience of growing old. Chapters in the book focus on concepts and themes that analyse Soviet ageing…

Promotor: J.M. van den Broek Co-promotor: M.C. de Vries

In this PhD thesis, available data on the PK and/or PD of different targeted therapies, chemotherapy and immunotherapies obtained during both routine clinical practice and prospective clinical studies were analyzed.

Leiden University Libraries (UBL) has been able to acquire four remarkable medical manuscripts partly thanks to support from the Friends of Leiden University Libraries, the Pieter van Foreest Stichting and the Van de Sande Fonds. All four are largely written in Dutch and can be dated between 1595 and…

Promotores: W.J.G.M. Peijnenburg, G.R. de Snoo, Co-promotor: M.G. Vijver

Promotor: S.J. Edixhoven

PhD research recently completed by pharmacologist Margreke Brill shows that morbidly obese patients should be given a different dosage of the drugs Cefazolin and Midazolam. This could also apply to other drugs such as anti-cancer drugs as well as antibiotics and Margreke Brill is advocating a change…

Make more fluid: In condensed matter systems, electrons can acquire unusual properties from their interaction with the atomic lattice.

The fact that scientists are increasingly better able to access molecular cell and tissue data also brings with it a new challenge: how can scientists find the information they need for research among the vast amount of data available?

This thesis describes the implementation and on-sky demonstration of high-resolution integral-field spectroscopy for extreme adaptive optics systems that are used to find and characterize exoplanets.

In this work we describe three methods to improve the performance of Quantum Field Theory calculations.

A management strategy has been developed for field margins to reduce pesticide drift to non-target areas and to promote biodiversity on arable land. To this end, 3 and 6 m wide strips along the edges of winter wheat, sugar beet and potato crops have been left unsprayed with herbicides and insecticides…

Seven new Medical Delta professors revealed their research plans in a lecture marathon on 21 June. The professors at Leiden University, the LUMC, Delft University of Technology and the Erasmus Medical Centre Rotterdam operate at the interface between life sciences and health and technology.

Doctors and pharmacists should take greater account of obesity when dosing medicines. The distribution in the body and the breakdown of a medicine can vary considerably in obese patients. This is stated by clinical pharmacologist Catherijne Knibbe in the Annual Review of Pharmacology and Toxicology.

This thesis investigates the relations between metabolism and anatomy through the use of Magnetic Resonance Imaging (MRI).

Promotor: H.J.M. de Groot, Co-Promotor: A. Alia

LUMC researcher Marius Staring will receive a $ 200,000 grant from the Chan Zuckerberg Initiative to improve the accessibility, interoperability and efficiency of the Elastix imaging software. This will give the popular 2003 software package a much-needed new impulse.

According to the LUMC, patients experience 30% fewer serious side effects when medication doses are tailored to their DNA.

The redox-conversion reaction of metal-disulfide and metal-thiolate complexes are important, as they may shed light on electron-transfer reactions that often occur in Nature.

On the largest scale, the Universe resembles a cosmic spiderweb. Most galaxies coexist in small groups within the threads of this web. At the nodes of the threads are enormous groups of galaxies forming the largest structures in the universe still held together by gravity: clusters of galaxies.

Premature babies almost always require treatment with medication. Doctors usually determine the dosages based on data from children who were not born prematurely, while preterm infants often develop differently. Medication researcher Aline Engbers investigated three commonly used drugs, focusing on…

Promotor: S.J. Edixhoven Co-promotor: L. van Geemen, P. Parent

Leiden researchers have developed an app that doctors can use to more easily determine the right dosage of medication for corona patients. At the moment, doctors are prescribing many existing kinds of medication to patients. Using the app, they can determine a safe and effective dosage.

The LIACS Media Lab has received a research grant from the worldwide leading graphics hardware company NVIDIA. The grant exists of newly developed hardware utilizing thousands of processors. LIACS researchers will use it to investigate deep learning in understanding imagery from sources such as MRI…

Boudewijn Röell, Leiden medical student and rower with the Asopos rowing club, has won a bronze medal with the Dutch Rowing Eight at the Olympic Games in Rio.

‘The Survival of Pliny in Padua. The Botanical Renaissance and the Transformation of Classical Scholarship’ in: Transformations of the Classics via Early Modern Commentaries, ed. by K.A.E. Enenkel. Intersections 29 (Leiden/Boston: Brill, forthcoming autumn 2013), pp. 327-62.

Promotores: P. Stevenhagen, E. Fouvry (Univeriste Paris Saclay)

Why do black holes emit thermal radiation? And how does a closed quantum system thermalize?

Subproject of the NWO Smart Culture Grant research project 'The Critical Visitor'.

Medical research is often exaggerated in the news. Medical journalists are not the only ones guilty of such sloppiness; results are also often exaggerated in academic press releases. This was the conclusion of a study by researchers from Leiden University Medical Center (LUMC) and Leiden University,…

A tried and tested medication for treating ADHD works differently than expected in the brains of healthy individuals during rest: rather than stimulating brain activity, it suppresses it.

Five of the new Medical Delta professors who now hold an appointment at multiple institutions are affiliated with Leiden University/LUMC. They are psychologist Andrea Evers and four LUMC professors.

Persistent somatic symptoms are long term symptoms that lack a clear medical explanation. These symptoms have a high prevalence where most people know someone who experiences such symptoms or they experience such symptoms themselves. Symptoms can vary greatly in and between people. While one person…

How do humans control their thoughts and actions, and what can high-field brain scanning reveal about the underlying processes?

The Geneva Conventions and customary international humanitarian law clearly prohibit any attacks on medical units and establishments during armed conflicts. Unfortunately, despite this clear prohibition, medical personnel and medical facilities continue to be the subject of attacks. Doctors now risk…

Natashe Lemos Dekker addresses the experiences of family members of people with dementia as they expressed their sense of gradually losing the person with dementia in the article 'Anticipatory Grief in Dementia: An Ethnographic Study of Loss and Connection' published in Culture, Medicine, and Psychi…

This ethnographic exploration of anticipation published in the Journal of the Royal Anthropology Institute draws on fieldwork among people with dementia and their families in the Netherlands.

With the powerful electron microscopes at NeCEN we study abnormalities in cells of blood vessels in cardiovascular disease, the interaction between pathogens and hosts in infectious diseases, molecular processes that cause cancer and the interaction between drugs and target proteins. Drug development…

This project investigates the role of art in the public and academic debate on biosolar energy

The insights leading to the present project firstly manifested themselves in 2008, when I worked with field recordings on the basis of relatively well-established notions in music composition studies, such as ‘musical material’ and écriture. With hindsight, I understand the outcomes of those first experiments…

In this thesis, we show that we can use Shimura’s CM theory to explicitly compute the Hilbert class field of any primitive quartic CM field.

PhD defence

Professor of Radiology Lioe-Fee de Geus-Oei was already a professor at LUMC and the University of Twente. As Medical Delta professor, she has now also been appointed at Delft University of Technology. 'Talking with people from other disciplines always makes me immensely humble, because they look at…

This project, commissioned by DG Research and Innovation, aims to provide information for policies that lead to the creation and improvement of the conditions which will allow researchers and European industries to safely master the properties of nanomaterials and to innovate with nanotechnology.

The different kinds of cultural perspectives on health and disease of the participants are related to their knowledge, beliefs, values and practices manifested in various forms of lifestyle in Indonesia. The cultural diversity of the population is also related to differences in health behaviour.