Development of micro-scale analytical tools to be used to address relevant biomedical questions in the field of neuroscience, and other application areas intrinsically dealing with small sample amounts.

The Biomedical Microscale Analytics group is led by Dr. Rawi Ramautar. In present-day metabolomics, and bioanalysis in general, the analytical toolbox used encounters difficulties for the analysis of limited amounts of biological samples. As a result, a significant number of crucial biomedical/clinical…

Although sexual abstinence before marriage is no longer the central message in The Netherlands the affective relationship as a criterion for professionals within criminal justice can be seen as a more contemporary version of marriage.

What is the most effective way to eliminate tumour cells? The DNA repair mechanism could play an important role in increasing the effectiveness of chemotherapy in the fight against cancerous cells. If we are to influence this mechanism, we need fundamental knowledge about how the mechanism works.

Chemical reactions go hand-in-hand with an energy exchange with the environment in which they take place. Surfaces offer a variety of energy dissipation channels, constituted by the nuclear and electronic degrees of freedom of the atoms at the interface. Aiming at an improved future harvesting of energy,…

For many system in statistical physics the microcanonical and canonical ensemble are equivalent in the thermodynamic limit, but not for all.

Cardiovascular diseases are among the most frequent causes of death in the world. The main underlying pathology of cardiovascular diseases is the development of atherosclerosis in the medium and large-sized arteries.

PhD candidates carry out a programme of independent research and additional limited) course work, culminating in production of a PhD thesis in typically 4 years.

Are you coming to Leiden University by car? Read about the parking possibilities.

Detecting nanoscopic objects plays an important role in nanoscience in particular, in the rapidly growing field of nanobiology. The forebear to modern super-resolution microscopy for single molecule investigation, is fluorescence microscopy.

This dissertation examines how we can reconstruct physical activity by looking at variations in the shape of muscle attachment sites ( ‘entheses’) on the human skeleton. It evaluates two post-medieval contexts; rural Middenbeemster and urban Aalst.

PhD candidates carry out a programme of independent research and additional (limited) course work, culminating in production of a PhD thesis in typically 4 years.

PhD candidates carry out a programme of independent research and additional (limited) course work, culminating in production of a PhD thesis in typically 4 years.

The dissociative chemisorption of methane on metal surfaces is of fundamental and practical interest, being a rate-limiting step in the steam reforming process. The reaction is best modeled with quantum dynamics calculations, but these are currently not guaranteed to produce accurate results because…

The invention of neural networks marks a critical milestone in the pursuit of true artificial intelligence. Despite their impressive performance on various tasks, these networks face limitations in learning efficiently as they are often trained from scratch.

PhD candidates carry out a programme of independent research and additional (limited) course work, culminating in production of a PhD thesis in typically 4 years.

In this article, Barrie Sander together with his colleagues explore whether fairness in digital governance inadvertently entrenches structural inequalities

Cancer is considered the silent pandemic of the 21st century and the second leading cause of death worldwide.

In the Netherlands approximately 130 out of 700 secondary schools offer a bilingual stream. However, research about CLIL (Content and Language Integrated Learning) is limited. With her dissertation Evelyn van Kampen (PhD student at ICLON) wants to contribute to the understanding of the nature and range…

Jaroslaw Kantorowicz examines how strategic climate litigation influences public attitudes on climate policy, using a UK experiment to explore legal cues.

PhD candidates carry out a programme of independent research and additional (limited) course work, culminating in production of a PhD thesis in typically 4 years.

In this article, Vanessa Newby, assistant professor at the Institute of Security and Global Affairs, discusses credibility in peace operations. This article argues that credibility in peace operations must be built for both deterrence and cooperation purposes.

Generally the data from remote sensing surveys - the scanning of the earth by satellite or aircraft in order to obtain information about it - is screened manually in archaeology. However, constant monitoring of the earth's surface causes a huge influx of data of high complexity and high quality. To…

Biopolymer sequencing with graphene edge-based tunnel junctions has the potential to overcome current limitations with the third generation of sequencing based on biological nanopores.

This thesis utilises the exceptional sensitivity and resolution of LOFAR to explore the low-frequency Universe, while simultaneously advancing the telescope's capabilities to enable new scientific discovery.

Hoye proposes that concerns about virtues of the sovereign are essential for understanding Hobbes's both his political thinking and his political critique.

PhD candidates carry out a programme of independent research and additional (limited) course work, culminating in production of a PhD thesis in typically 4 years.

In this thesis, we develop a novel technique called Optical Near-field Electron Microscopy (ONEM), which aims to combine the advantages of both optical and electron microscopy: the high resolution of electron microscopy and the low sample damage of optical microscopy.

On 13 October 2021 Ross Spence defended the thesis 'Collateral Transactions and Shadow Banking'. The doctoral research was supervised by Prof. M. Haentjens and Prof. A.M. Pacces (UvA).

Dissolution processes – next to aggregation processes - play an important role for fate prediction and environmental risk assessment of metal-based nanoparticles (MNPs). It is challenging to predict the kinetics of the dissolution process of MNPs in complex systems such as we can find in in vivo and…

Participation is free, but registration is required as limited seats are available. Registration includes coffee breaks, lunch, and drinks during the poster session (plus speakers’ dinner for all invited lecturers).

Kidney transplantation is a major advance of modern medicine. This course will give you state of the art updates about what used to be an experimental, risky, and very limited treatment option more than 50 years ago and is now routinely performed in many countries worldwide.

Optimization tasks in practice have multifaceted challenges as they are often black box, subject to multiple equality and inequality constraints and expensive to evaluate.

What is the state of access to justice in real property grievances in today’s Libya, and how should it be improved?

The last decades it is increasingly recognized that acute as well as chronic postoperative pain is an important problem. Treatment and prevention of postoperative pain is a challenge, especially in special patient populations where there is only limited guidance on how to optimally use opioids.

Promotor: Prof.dr. G.P. van Wezel, Co-Promotor: E. Vijgenboom

On 21 February 2019, Ruben Zandvliet defended his thesis 'Trade, Investment and Labour: Interactions in International Law'. The doctoral research was supervised by Prof. dr. N.J. Schrijver.

On 20 January 2022, Marco Stam defended the thesis 'Essays on Welfare Benefits, Employment, and Crime'. The doctoral research was supervised by Prof. M.G. Knoef.

The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.

Growth hormone profiles are pulsatile and highly variable between individuals, limiting the implementation of mathemathical models to quantify an individual's secretion.

Tom Buitelaar is an Assistant Professor in the War, Peace & Justice programme of the Institute of Security and Global Affairs. This paper discusses four important challenges to the involvement of UN peace operations in international criminal justice: its effects on host state relations, peace and justice…