753 search results for “mycobacteria maria infection” in the Public website
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Annemarie Meijer appointed full Professor of Immunobiology
Annemarie Meijer is appointed full Professor of Immunobiology. Meijer’s research focuses on immunobiology and infectious disease. She uses the zebrafish as a model for understanding mechanisms of host immune defense against intracellular bacterial pathogens.
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Influenza T-cell epitope-loaded virosomes adjuvanted with CpG as a potential influenza vaccine
Influenza CD8(+) T-cell epitopes are conserved amongst influenza strains and can be recognized by influenza-specific cytotoxic T-cells (CTLs), which can rapidly clear infected cells. An influenza peptide vaccine that elicits these CTLs would therefore be an alternative to current influenza vaccines,…
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Specters of Cavafy
Haunting the future through poetry
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Projects
An overview of Quantitative Pharmacology projects
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Collaborations
Click on the images to see the full event pages.
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Spinoza and Stevin Prizes for three Leiden professors
Three Leiden professors have recently been awarded the most prestigious scientific accolade in the Netherlands: Maria Yazdanbakhsh and Marc Koper have been awarded a Spinoza Prize and Judi Mesman a Stevin Prize. They received their prizes on 13 October.
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Andean Mummies Journey to European Museums 1810-1970
A look into the political history of collecting and the collections of Andean mummies in Western European museums from 1830-1930 through archaeology and paleoimaging.
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Bioprinting human tissues for drug testing
Bioprinters that enable scientists to engineer complex tissues and organs. It sounds like science-fiction, but not for the scientists of the Alireza Mashaghi lab at the Leiden Academic Centre for Drug Research. The lab has recently been equipped with two state-of-the-art bioprinters: BioX and LumenX+.…
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Functions of leptin in tuberculosis and diabetes: multi-omics studies across species
In this thesis, I study 1) metabolic alterations in tuberculosis related to wasting syndrome in human patients as well as in rodent and fish animal models. 2) effects of the mutation of the leptin gene on cachexia and diabetes in rodent and zebrafish animal models.
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Contact
Contact details and staff overview of the Leiden University Graduate School of Social and Behavioural Sciences.
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(Un)timely Crises Chronotopes and Critique
This book explores how ‘crisis’ - as a narrative, concept, grammar, and experience - structures time and space.
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Replicated molecules reveal hiding method of bacteria
Specific fatty acid-sugar molecules allow leprosy bacteria, among others, to hide from our immune system. How exactly is not entirely clear. Hessel van Dijk, who received his PhD on 13 October, replicated the molecules, helping to solve a piece of the puzzle. Van Dijk's dissertation is titled: Synthesis…
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Better vaccines against malaria and tuberculosis
The infectious diseases malaria and tuberculosis are responsible for 2.1 million deaths every year. Leiden researchers are currently testing a new tuberculosis vaccine.
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Ariane Briegel: 'AI literally opens new worlds for the life sciences'
Bacteria caught red-handed, deeply frozen just as they were about to cause Lyme’s disease. Ariane Briegel is wildly enthusiastic about the wonders she observes thanks to three elements: a freezing technique, a camera-equipped microscope, and AI. ‘It’s fascinating. Every single cell is different.’
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About the Food Citizens? project team
Cristina Grasseni, Federico de Musso, Ola Gracjasz, Maria Vasile, Vincent Walstra and Marilena Poulopoulou are part of the 'Food citizens?' Research project.
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Barbarian: Explorations of a Western Concept in Theory, Literature and the Arts Vol. 2: The Twentieth and Twenty-First Centuries
The second and final volume of this co-authored study has just been published by J.B. Metzler. This second monograph explores the history of the concept of barbarism in the twentieth and twenty-first centuries.
- Meet our staff
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Indonesia
This is an Erasmus+ International Credit Mobility project of Leiden University Medical Center and the Faculty of Science with two universities in Indonesia.
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White blood cells in transparent embryos
Leiden molecular cell biologists in the research group of Annemarie Meijer have discovered novel early macrophage-specific genes in zebrafish, including a signal transducer pivotal for the migration of macrophages in the innate immune response to bacterial infection. Their findings were published on…
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Major Leiden symposium on TB bacteria
More than 1.3 million people worldwide die of tuberculosis (TB) each year, making research on its prevention and control essential. Researchers from various disciplines in Leiden are studying TB. A symposium on 24 March will highlight different activities in the hope of boosting nationwide collabora…
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Learning from Mycobacterium Infections in Animals – Immunodiagnostics for Leprosy and Tuberculosis in Humans and Animals
PhD defence
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Chemical biology of antigen presentation by MHC molecules
MHC class I and MHC class II molecules present peptides to the immune system to drive proper T cell responses. Pharmacological modulation of T-cell responses can offer treatment options for a range of immune-related diseases.
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Arts as an Interface of Law and Justice: Affirmation, Disturbance, Disruption
On 25 Februarry 2021 Hart Bloomsbury brings out a monograph by Frans-Willem Korsten: Arts as an Interface of Law and Justice: Affirmation, Disturbance, Disruption. Its working title was 'Annoyance' but that did not sell. A sign in itself; most struggles for justice have been considered as annoying.
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Subjects Barbarian, Monstrous, and Wild: Encounters in the Arts and Contemporary Politics
Subjects Barbarian, Monstrous, and Wild responds to a contemporary political climate in which historically invested figures of otherness—barbarians, savages, monsters—have become common discursive currency.
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Publications
A selection of recent publications from the Plant BioDynamics Laboratory.
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Linguistic Advances in Central American Spanish
Covering all seven countries on the isthmus, this volume presents the first collection of original linguistic studies on Central American Spanish varieties, which have long been neglected in Hispanic Linguistics.
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Leiden University scientists - Working at Leiden University
Nobody is better qualified to tell you what it is like to work at Leiden University than the employees themselves. Watch the videos and meet your future colleagues. They will be happy to share their experiences with you.
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Spanish-English Codeswitching in the Caribbean and the US
This volume provides a sample of the most recent studies on Spanish-English codeswitching both in the Caribbean and among bilinguals in the United States.
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Multidisciplinary Approaches to Bilingualism in the Hispanic and Lusophone World
This volume offers a multidisciplinary view of cutting-edge research on bilingualism in Spanish and Portuguese-speaking regions, with the aim of building a bridge between sub-fields and approaches that often find themselves isolated from one another.
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Social Policy, Poverty, and Inequality in Ecuador 1980-2021 [Política social, pobreza y desigualdad en el Ecuador 1980-2021]
This book offers a detailed analysis of social policy in Ecuador, covering its evolution over the past four decades. It examines how social relations and institutional frameworks have influenced concepts of well-being, the implemented policies, and the outcomes achieved.
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Workshop: Other Forms of Embodying Knowledge
Pau(la) Chaves Bonilla aka La ChicaScratch is a choreographer, performance artist and queer grassroots organiser born and raised in Colombia and based in The Netherlands, co-founder of the Papaya Kuir collective led by Latinx trans and queer migrants/refugees. BOCA had the privilege of inviting Paula…
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G.F. Stout and the Psychological Origins of Analytic
The philosopher and psychologist G.F. Stout was the teacher of Moore and Russell around 1894. This book shows that Stout's ideas have played a role in Moore and Russell's development from their early idealism towards analytic realism, where Stout's ideas often find their origin in early phenomenolog…
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Mechanisms of vaccines against viral infections
PhD defence
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Horizon2020 grant for toxicologist Bob van de Water
An international research consortium led by Bob van de Water, Professor of Toxicology at Leiden University, has been awarded a prestigious Horizon2020 grant of 30 million euros.
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New insights into chemical sensing of the human pathogen for cholera
The bacterium Vibrio cholerae is a serious threat to our health because it is the causative agent of cholera. Worldwide, over a billion people per year are at risk of cholera infection. New strains of V. cholerae are resistant to the multiple drugs used to treat cholera, meaning that new types of drugs…
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EU awards 18 million euros for research into new antibiotics
An international consortium of research groups is aiming to develop novel antibiotics against the tuberculosis bacteria and two other deadly bacteria. The European Union has awarded a total of 18 million euros to the RespiriTB and RespiriNTM projects. Researchers from the Leiden University Medical Centre…
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Respiratory health and disease in the Netherlands
Studying the impact of urbanisation on the respiratory health of past Dutch populations (1200-1850 CE).
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Development & Disease
Living systems scale from unicellular microbes to complex multispecies communities that constantly change over time. Within the theme Development & Disease, we enhance our fundamental understanding of development and homeostasis of living cells and systems. We analyze the normal situation and how stresses…
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Courses in Academic English
To help you improve your skills in communicating about your research in English, the Graduate School has an in-house Academic English Lecturer.
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Tomasz PrajsnarFaculty of Science
t.k.prajsnar@biology.leidenuniv.nl | +31 71 527 4950
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Jaap van DisselFaculty of Medicine
j.t.van_dissel@lumc.nl | 071 5269111
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A new target in the fight against Tuberculosis: exploring key enzymes in TB-causing bacteria
How do lipases in Mycobacterium tuberculosis help the bacteria survive, and can we target them to create new antibiotics?
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Development and evaluation of evidence based self-help and online programs for people with a somatic stressor and depressive symptoms
What is the effectiveness of (booklet or online) self-help programmes for people with somatic stressors and depressive symptoms? What works best for whom? How to improve motivation and adherence?
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Host-Microbe Interactions
Microbes influence and respond to other organisms. This theme explores the dynamic relationships within plant and animal microbiomes, and the immune responses that govern host defense. Using model systems such as zebrafish, insects, and plants, we investigate fundamental processes and engineer microbes…
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Japan
This is an Erasmus+ International Credit Mobility project of the Leiden University Medical Center with Nagasaki University.
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Buccal and sublingual vaccine delivery
Because of their large surface area and immunological competence, mucosal tissues are attractive administration and target sites for vaccination.
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Optimizing antifungal treatment through pharmacometrics: dosing considerations to enhance outcome
Fungal infections pose a significant threat to individuals with compromised immune systems and despite advancements in diagnosis and treatment, they continue to jeopardize patient’s health.
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Comparative biology of common and grey seals along the Dutch coast : stranding, disease, rehabilitation and conservation
Promotores: H.A. Udo De Haes, P.M. Brakefield
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Microstructural and Metabolic Alterations in the Zebrafish Brain Induced by Toll-Like Receptor 2 Deficiency
Advanced UHF MRI techniques provide powerful tools for studying the zebrafish brain, an emerging model in neurological research. In this work, various MRI and localized MRS methods are optimized and employed for UHF strength for studying the zebrafish brain.
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Concepts and applications for evidence-based dosing in morbidly obese patients before and after weight loss surgery
Promotor: C.A.J. Knibbe, Co-promotores: H.P.A. van Dongen, B. van Ramshorst