Ms. Monica Klasing Chen defended her thesis on 16 December 2020

In today's volatile market environments, companies must be able to continuously innovate. In this context, innovation does not only refer to the development of new products or business models but often also affects the entire organization, which has to transform its structures, processes, and ways of…

Ineke Smit defended her thesis on 17 September 2019

The post-PhD phase is discussed during the many formal and informal meetings PhD candidates have with their supervisors. However, there are also various online sources, workshops and events available to PhD candidates to better prepare for the next step.

On Wednesday 14 May 2025 Remzi Çakırlar successfully defended a doctoral thesis and graduated.

Research on the process of artisanal and small-scale mining (ASM) in West-Africa

Mathilde Mechling defended her thesis on 28 january 2020.

What are the characteristics of a curriculum that stimulates the development of student agency in secondary education? How can teachers respond to different agency profiles of students, and what is the relationship with academic performance, well-being, and stress?

Wijayanto defended his thesis on 17 January 2019

As a PhD candidate, you can experience problems in the relationship with your supervisor or co-supervisor, with your immediate superior, colleagues or other PhD candidates. If you are unable to solve these problems, you can turn to a confidential advisor for PhD candidates.

This research proposal focuses on historically informed performance (HIP) and adaptive performance practices within the late 18th-century German musical context.

On the 26th of May Sudarmoko successfully defended a doctoral thesis and graduated.

Lu, Man defended his thesis on 28 September 2017.

On 12 April 2022 Alok Oak successfully defended a doctoral thesis and graduated.

Barrier function is the natural role of the skin. The lipid matrix present in the outermost layer of the skin, the stratum corneum is important for this function.

The Graduate School Management (GSM) module is a registration and monitoring module for you and your supervisor(s). All information is stored in a uniform way and made accessible in one place. Converis is the software behind LUCRIS.

In this thesis we construct an extension associated with the Furstenberg compactification of symmetric space of noncompact type. From this extension we get a cycle in equivariant KK-theory representing the extension. The construction of the extension and the corresponding cycle is a generalization of…

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In this thesis, we describe the potential of cell mechanical phenotyping for immune cell characterization, diagnosis, drug testing, as well as treatment of disease.

This thesis describes the evaluation of novel natural products with antibacterial activity enabled by total chemical synthesis.

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Calamus javensis is polymorphic. Morphometry and molecular approach resulted in all names used in the complex are regarded as synonyms of C. javensis except C. tenompokensis, which is retained as a distinct species. One variety is here recognized, C. javensis var. polyphyllus (including C. acuminatu…

This thesis addresses questions on effectively using variational quantum circuits for machine learning tasks.

Being a supervisor is a demanding job. With these golden rules in mind, you'll do just fine. You can keep reading below, or download the PDF on the right for a visual representation.

Being a supervisor is a demanding job. With these golden rules in mind, you'll do just fine. You can keep reading below, or you can download the PDF in which you find a visual representation on the rules.

CSC-Leiden University joint scholarship program

The thesis describes the development, synthesis and biological evaluation of several proteasome inhibitor designs. Mainly, this work focusses on designing proteasome inhibitors that selectively inhibit the immunoproteasome, while leaving the constitutive proteasome mostly, if not completely, untouch…

Exploring metabolomics-based biomarkers for diagnosis and treatment response monitoring of community-acquired pneumonia

This dissertation presents four separate chapters, all striving towards the same goal: to understand dynamic phenomena occurring in dynamic networks and to explore the emergence of equilibrium in a broad sense.

This thesis has shed light on some of the ways in which the local electrolyte composition can differ from the bulk and how these changes in the local reaction environment can determine the activity and/or selectivity of two important electrocatalytic reactions, namely, electrochemical CO2 reduction…

This thesis describes the design and synthesis of novel small molecules based on sulfur-containing heterocycles for the inhibition of glycosidases and glycosyltransferases related to Fabry and Pompe disease.

To conclude, this thesis provides valuable methodological insights to address data gaps and improve environmental impact assessments within the circular economy, with a particular focus on product reuse and sharing practices. Through empirical analysis and innovative approaches, it aims to support informed…

Central Limit Theorem associated to a particular case of ergodic total automorphisms. Finally, Chapter 6 proves that the isoperiodic foliation is connected for a meromorphic differential with three poles on a torus.

A framework for prospective/ex-ante life cycle assessment (LCA) and ecological risk assessment (ERA) of emerging technologies is developed and applied to a case study of III-V/silicon photovoltaic panels.

uman skin equivalents (HSEs) are in vitro 3D-skin models that mimic many aspects of the native human skin (NHS) and can be a valuable tool.

Het proefschrift omschrijft de chemische synthese van fenolische glycolipiden van verschillende mycobacteriën met het doel om deze te kunnen gebruiken voor immunologisch onderzoek.

In my thesis I study Majorana fermions from three different perspectives. The first one corresponds to non-interacting Majorana fermions that, however, pose non-trivial topological properties. The second one corresponds to strongly interacting Majoranas and the third to relic neutrinos. No one knows…

Design and synthesis of two 3-substituted swainsonine derivatives with the aim to improve the potency and selectivity towards Golgi alpha-mannosidase II.

In the thesis we demonstrated an 85% state transfer efficiency between two mechanical modes coupled to a common optical mode via stimulated Raman adiabatic passage (STIRAP) in the classical regime. We also showed possibilities to manipulate quantum states of the mechanical modes via STIRAP.

Synthetic methodlogy is described, aiding in the synthetic preparation of putative inhibitors of retaining and inverting glycosidases and glycosyl transferases. All constructs are cyclophellitol-based cyclitols.

The aim of the research described in this thesis was to use structure-based design to optimise multiple properties of aryl sulfoxide monoacylglycerol lipase inhibitors as anti-inflammatory analgesics.

Although bacteria are usually invisible to the naked eye, they are the silent force behind many processes in our daily lives.

Thesis focused on uncovering the underlying mechanisms of the lysosomal storage disorders Gaucher's disease using chemical tools, biochemical assays and lipidomics.