One of the most crucial aspects of our behaviour is our motivation to explore novel environments and interact with new people. This became painfully clear during the COVID-19 lockdowns, when many people suffered from lack of new experiences and real-life social interactions. The relevance of novelty…

Can SMILE, our multi-component intervention, which combines cognitive-behavioural therapy for insomnia, mindfulness, stress, and lifestyle components, improve sleep quality? Can it also improve mood and quality of life and prevent depression and anxiety in the long term?

Our ability to learn and control movements is essential for engaging in goal-directed behaviour. From buttoning your shirt and driving a car, to cooking dinner and brushing your teeth -- our actions in daily life rely on this ability.

The research connected to this topic is related to Work and health.

In the traditional theory of linear elasticity, superposition dictates that the response of a material does not depend on the sequence of the applied mechanical actuations.

Like a mixture of oil and water, lipid membranes separate into two liquid phases.

Mechanical metamaterials are carefully engineered materials whose properties are controlled by their structure, not by their composition, which allows using metamaterials to study and control physical effects in detail⁠.

Within the LUMC medical research profile Translational Neuroscience innovative multidisciplinary research is performed on a number of severe disorders of the brain, nerves and muscles.

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PhD at the Natural Product Laboratory, Institute of Biology, Leiden University - the Netherlands

Errors are everywhere, and mechanical failures are especially common: buckled grain silos and cracked support columns are, justly, seen as an issue to be avoided.

This thesis focuses on amyloid proteins, a class of proteins that convert into amyloid fibrils.

“We are proud and happy to receive this grant. It will enable us to do truly innovative fundamental research with a direct link to practical applications.” Michiel Westenberg is looking forward to investigate the effects of age and social anxiety on eye-contact. Together with Esther van den Bos he has…

Lecture, PCNI Research Seminar

Activity-based protein profiling (ABPP, also termed chemical proteomics), is one of the pillars of chemical biology, and at LED3 we have taken it to the next level. ABPP allows the assessment of protein function in live cells and tissues, which means that the activity of a complete protein family can…

Individuals suffering from social anxiety disorder (SAD) consistently avoid eye contact. However, in a non-clinical population, gaze avoidance in socially anxious individuals depends on social situations, Jiemiao Chen saw in a series of experiments, for which she used wearable eye-trackers. On 25 April…

Bij Amsterdam University Press verschijnt 'Imams in Western Europe. Developments, Transformations and Institutional Challenges' onder redactie van Mohammed Hashas, Jan Jaap de Ruiter en Niels Valdemar Vinding, een publicatie waarin tal van zaken met betrekking tot imams in Europa behandeld worden. De…

In the specialisation Clinical Psychology, part of the Master in Psychology, you gain extensive knowledge on the asessment and treatment of mental disorders.

Lifelong learning | “Even though we were spread across five continents, there was a strong sense of connection.”

Psychology graduates acquire skills useful in a variety of jobs. Whether helping people with mental disorders, researching the brain or deciding who should be hired at a company, psychologists can do it.

Our lectures are open to anyone with an interest Find your inspiration for interdisciplinary research

There's a myth that people with autism avoid eye contact in conversations. This can come across as indifferent. Unjustified, stresses Jiayin Zhao, who is doing her PhD research on the socio-emotional development of children with autism. 'That people with autism don't care is anything but true.'

Political games have existed throughout history, but what is the role of 'play' in the way the American political world has developed? University lecturer Sara Polak has received an ERC Starting Grant to investigate this.

Neuroimaging research has greatly advanced our insights on how the brain is organized. Now is the time for the next step: Imagine what would be possible when we cannot only map brain-functioning, but use neuroimaging to voluntarily regulate brain-activity!

Leiden University neuropsychologists have shown that customised intervention pays off. A new fundamental research-based approach in children who are in danger of going off the rails has delivered spectacular results.

Young children, adolescents and students may experience learning difficulties as a result of lack of sleep. Dr Kristiaan van der Heijden investigates sleep problems and solutions for various age groups.

This is an Erasmus+ International Credit Mobility project of Leiden University Medical Center with Boston Children’s Hospital in the USA.

Our immune system protects us against disease, but every now and then, something goes wrong: an enemy invades our bodies or our immune system attacks our own cells and we become ill. Doctors and researchers at the Leiden University Medical Center (LUMC) want to be able to manipulate the immune system…

Serious forms of anxiety concerning other people’s opinions can hinder teenagers at school in social interactions or carrying out tasks. Psychologist Anne Miers is looking for ways to reduce this so-called ‘social anxiety’.

In case of serious illness, treatment in the Intensive Care Unit (IC) may be necessary. Intensive care treatments has improved over the years and more and more seriously ill patients are surviving admission to the ICU. This favorable development however has a downside since long-term consequences of…

The master's specialisation Clinical Neuropsychology consists of three main parts: the mandatory and elective courses, a thesis and an internship.

In the future, physicians may be able to identify dementia much earlier than they can today because a computer algorithm will be able to predict from brain scans how our memory is going to develop.

The STAP study examines the cost-effectiveness of Written Exposure Therapy (WET) for post-traumatic stress disorder (PTSD) symptoms in primary care settings.

Our mission is to improve the description, prediction, understanding and the prevention and treatment of mood disorders, including unipolar and bipolar depression, as well as suicidal thoughts, feelings, and behaviors. To tackle this ambitious mission, we focus on several research streams.

A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers.

Using brain imaging to discover the area in the brain that recognizes emotion.

Half the world's population is introverted and comes home drained after an evening of drinks. Their social battery is empty. 'People with autism have a similar experience, but much more intense,' says Boya Li, who researches emotional regulation in children with autism and hearing impairment. Does this…

Macrophages – the front line of our immune system – protect us from infections. But in the case of the tuberculosis bacteria, this often goes wrong. The group of Annemarie Meijer from the Leiden Institute of Biology has now discovered that macrophages in zebrafish are better able to eliminate tuberculosis…

This study tests whether behavioural problems at a young age are related to early reading and mathematics development.

Legitimacy is generally a term that is associated with the state. The term surfaces when there are problems with state legitimacy—when it is lacking or absent. This present volume attempts to think through the relevance of the concept of legitimacy for other political actors than the state.

Majorana fermions in superconductors are the subgap quasiparticle excitations that are their own antiparticles.

The group is involved in training in areas of diagnostic skills, treatment/prevention/intervention, neuropsychological assessment, behavioral observations, clinical interviewing, knowledge of intellectual disability, autism, ADHD, psychosis and aggression.

The genetic information of all living organisms is contained in their DNA. Cells modify the degree of DNA compaction by epigenetics, which largely determines what genes are read out and which genes are transcriptionally silent.

The progressive loss and degeneration of dopaminergic neurons is a major pathological hallmark of Parkinson's disease (PD). The onset and progression of PD can be triggered by multiple risk factors, for instance, genetic mutation, environmental exposure, and aging.

In the first part of this thesis we study the geometry of folding patterns.

Childhood sexual abuse is a common problem, with approximately one in five girls and one in 13 boys worldwide experiencing some form of sexual abuse before the age of 18. Despite its high prevalence, many individuals remain silent about these experiences, often delaying disclosure for years, with one…

Promotor: Prof.dr. M. Danhof, Co-promotor: E.C.M. de Lange

Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.

Transcutaneous vagus nerve stimulation (tVNS) was tested in chronic worriers. tVNS may reduce spontaneously occurring negative thought intrusions. After a worry induction, there was no longer an effect of tVNS. tVNS did not affect physiological responding to worrying.

We perform multidisciplinary research at molecular, cellular, and organismal levels of animal biology to increase fundamental understanding of health and disease.