A new therapy for the serious Graft-versus-Host disease

The kidneys play a major role in the elimination of drugs. In children, the exact age-related physiological changes underlying kidney function remain largely unknown.

Find out how to apply for Transfusion Medicine and Cellular and Tissue Therapies.

Therapeutic proteins have revolutionized the treatment of many severe diseases like multiple sclerosis, haemophilia, diabetes and many more. Unfortunately, even recombinant proteins with structures (almost) identical to those of their endogenous counterparts often induce the formation of anti drug antibodies…

Clinical psychology is a discipline concerned with the application of psychological science to the assessment and treatment of mental disorders.

Study information

PhD defence

PhD defence

The division of BioTherapeutics consists of the former divisions Biopharmaceutics and Drug Delivery Technology.

Primary Objective: The primary aim of the proposed RCT is to evaluate whether LF-TLP in blended form as an indicated prevention for anxiety complaints is more (cost-) effective than TAU according to the NHG guideline Anxiety. We hypothesize that in comparison to TAU, LF-TLP will result in a significantly…

Providing each cancer patient with the right treatment remains a challenge. Oncode Accelerator aims to change this by innovating the way we develop cancer treatments, thus ensuring the patient is at the heart of the process. Leiden University, the LUMC and other partners will implement this new way…

Our research programme collaborates with all kinds of partners to achieve our goal: bringing scientific discoveries to the clinic as soon as possible.

Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm

How can we develop new chemical biology tools and approaches to understand and interfere with glucosylceramide metabolism in relation to Gaucher disease?

This Master enables you to practice professional activities such as: lead research projects and develop technically qualified projects in the field of transfusion medicine.

A major challenge in the formulation of biopharmaceuticals is to overcome their inherent instability during production, storage, transportation, handling and administration. We are studying underlying mechanisms of degradation of biopharmaceuticals (including therapeutic proteins, vaccines and advanced…

Valedictory lecture

Breast cancer is the most common cancer in women worldwide. Metastasis, the process by which cancer cells spread to other parts of the body, makes treatments less effective. It is important to unravel the mechanism of metastasis.

PhD defence

This thesis explored the molecular pharmacological mechanisms of targeting CB2R via investigation of novel drug discovery concepts such as target binding kinetics, allosteric modulation and biased signaling.

A therapeutic vaccine against HPV-16 (type 16 human papillomavirus) improves the survival rate in cervical cancer patients. A new study by ISA Pharmaceuticals B.V. (a Leiden-based biotechnology company) and the Leiden University Medical Center (LUMC) shows that this vaccine produces a more robust response…

An overview of Quantitative Pharmacology projects

Tuberculosis (TB) is associated with 1.5 million deaths annually. There is a need exists to optimize both current as well as novel antibiotic combination treatment strategies to improve the effectiveness and safety of treatments against TB.

The GMP Facility facilitates development and production of Advanced Therapy Medicinal Products (ATMPs) and chemical (peptide) synthesis.

Valedictory lecture

Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…

Imagine how much time, money and discomfort it would save: a personalised treatment for each individual patient. Precision medicine like this is coming ever closer, thanks in part to Elise Dusseldorp’s algorithms. They retrieve a wealth of information from research data.

A master's degree in Psychology at Leiden University combines theoretical knowledge with academic and professional skills, making you an attractive candidate for many employers.

Our team is involved in the translation and adaptation of several questionnaires, for research purposes. Information about each questionnaire is listed below.

As a psychologist and pilot, Bert Busscher is interested in the phenomenon often termed as fear of flying. Busscher discovered that the heart rate of a person undergoing a therapeutic flight shows how much they still suffer from fear of flying. The post-flight heart rate can even predict whether the…

The effective treatment of tuberculosis (TB) remains a major challenge to global health.

Students stream into the lecture hall, handing in their mobile phones at the door. Once everyone’s seated, silence descends and all eyes turn to the large screen at the front of the lecture hall. A live connection has been set up with the prison where Marco is a long-term inmate. Today, the students…

Registration for the Co-Align 2023 conference is open!

The LUMC has a longstanding tradition researching the role of the immune system in infectious diseases, transplantation and auto-immune diseases.

For more information regarding ongoing research projects, please contact Prof. Johan Kuiper.

This thesis examines silicon pore optics (SPO), a technology that exploits silicon wafers from the semiconductor industry to create extremely high quality X-ray optics, by studying its manufacturing process, applications, and prospects.

Elk jaar organiseert het LIBC in samenwerking met de gemeente Leiden een Publieksdag over hersenonderzoek.

Sepsis is a life-threatening condition caused by a dysregulated host response to infection, it is associated with significant morbidity, mortality, and with a high financial burden on global healthcare systems. Bacterial infections are the primary cause of sepsis, but the growing prevalence of antimicrobial…

Leiden biophysicist Stefano Coppola has received the prestigious AXA Research Fund postdoctoral fellowship. With this grant he can work for two years on a project to research the role of mechanical factors in the development of pancreatic cancer.

Professor Tom Huizinga (LUMC) specialises in rheumatoid arthritis. He joined forces with alumni and the Natuurwetenschappelijk Gezelschap Leiden, a society that aims to share knowledge of the natural sciences and medicine, to explore the symptoms of the disease. With this form of arthritis the fluid…

Ten Leiden students have received a prize from the Royal Holland Society of Sciences and Humanities (KHMW). They were nominated by their degree programme. Who are these students?

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