1,533 search results for “cognitive impairment” in the Public website
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How to get there
Route descriptions to CML by public transport or car
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The importance of free fatty acid chain length for the skin barrier function in atopic eczema patients
An important feature of atopic eczema (AE) is a decreased skin barrier function. The stratum corneum (SC) lipids - comprised of ceramides (CERs), free fatty acids (FFAs) and cholesterol - fulfill a predominant role in the skin barrier function.
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Nanomaterial safety for microbially-colonized hosts: Microbiota-mediated physisorption interactions and particle-specific toxicity
The external tissues of plants and animals are colonized by microbial communities termed microbiota. When organisms are exposed to environmental pollutants, these substances will therefore encounter microbiota at the exposure interface.
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Calcium-dependent regulation of auxin transport in plant development
The plant hormone auxin regulates plant growth and development through polar cell-to-cell transport-generated maxima and minima. PIN FORMED (PIN) auxin efflux carriers determine the direction of this auxin flow through their asymmetric placement on the plasma membrane (PM).
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On the efficacy of digitized storybooks for young learners with attention problems
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The added value of multimedia to repeated story book reading in preschool age
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Master Internship
Binnen de masteropleiding Education and Child Studies kun je verschillende typen stages lopen.
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Unraveling the drivers of antimicrobial pharmacokinetic variability in individuals with obesity and hospitalized patients with multimorbidity
Obesity may alter how a person absorbs, distributes, metabolizes or excretes medication. This thesis describes how obesity affects drug levels in the blood for antimicrobial agents, such as ciprofloxacin and fluconazole.
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Singing is silver, hearing is gold: impacts of local FoxP1 knockdowns on auditory perception and gene expression in female zebra finches
The experiments described in this thesis employ local lentiviral knockdowns in brain areas of female zebra finches followed by behavioural assays consisting of preference and Go/Nogo tasks.
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Developmental effects of polystyrene nanoparticles in the chicken embryo
There is concern about the threat that nanoplastics (NPs) may pose to both wildlife and humans. This thesis explores the mechanisms of toxicity of polystyrene nanoparticles (PS-NPs) in chicken embryo.
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Executive deficits, behavioural problems and early reading development
This study tests whether behavioural problems at a young age are related to early reading and mathematics development.
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A novel formulation for skin barrier repair : from ex vivo assessment towards clinical studies
The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.
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Human skin equivalents: understanding the lipid biosynthesis in the skin
There is considerable need for improved skin models to develop safe and efficient drugs for skin delivery as well as for cosmetic and chemical product testing on the skin.
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Novel factors modulating AGC kinase signaling-controlled polar auxin transport
The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.
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The Negative Effects of Bullying
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‘Kindersprache, Aphasie und allgemeine Lautgesetze’ revisited
The current project aims to revive the idea that sound inventories are structured according to a small set of universal principles by applying insights from current phonological theory and by making use of modern database technologies and data assessing methodologies.
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Psychosomatic Imagery. Photographic Reflections on Mental Disorders
Introduces a novel trope of photographic images dealing with states of mental disorders; focuses on photographs that visualize disturbed corporeal and mental perceptions of the world and connects medium-specific characteristics of photography to concepts from mental disorder studies.
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HuygensNiels Bohrweg 2, Leiden
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Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice, Nat. Chem. Biol. 2020
N-acylethanolamines (NAEs), which include the endocannabinoid anandamide, represent an important family of signaling lipids in the brain. The lack of chemical probes that modulate NAE biosynthesis in living systems hamper the understanding of the biological role of these lipids.
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Combating Bullying in Schools by Means of Self-Affirmation Training
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Nanoparticle – redox protein biohybrids
Artificial photosynthesis aims to produce fuels from solar energy using chemical processes. In semi-artificial photosynthesis, a hybrid approach is taken using both chemical and biotechnology approaches. We aim to develop hybrid systems between light-harvesting nanoparticles and redox-enzymes (oxidoreductases)…
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PoortgebouwRijnsburgerweg 10, Leiden
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Lipid model membrane systems as a tool for unraveling the underlying factors for skin barrier dysfunction
Barrier function is the natural role of the skin. The lipid matrix present in the outermost layer of the skin, the stratum corneum is important for this function.
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Emotion regulation in children and adolescents with an Autism Spectrum Disorder
Why do children with an Autism Spectrum Disorder (ASD) have difficulties with acquiring emotion regulation skills; and how is this related to their social impairments and comorbid psychopathology?
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The role of AGC kinases and auxin in male fertility
The thesis is about how auxin and AGC kinases regulate male fertility. The main AGC kinases studied in this thesis is PDK1, PDK2 and AGC1.5, AGC1.7.
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Cool little kids
Effectiveness of an early intervention program for anxiety-prone toddlers in the Netherlands
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Dutch Brain Cognition and Behavior Day
Conference
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Brain and Education Lab
The Brain and Education lab is a research group in the Institute of Education and Child Studies at Leiden University in the Netherlands. We use a Developmental Cognitive Neuroscience approach to study the development of complex cognitive processes involved in learning and academic skills such as reading…
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Participatory sense-making in physical play and dance improvisation: drawing meaningful connections between self, others and world.
The starting point of Hermans' research is how both children's physical play and dance improvisation by professionals can be considered somatic practices where sense-making manifests itself in and between bodies, and through movement.
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The interaction between Arousal and Cognitive Control
PhD defence
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Our team
Researchers from five different discplines work together in this interdisciplinary initiative.
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Zoo visitors can watch research into orangutan emotions
Researchers from Leiden University are working with Ouwehands Zoo to improve our understanding of emotions and intelligence in orangutans. Visitors to the zoo can now watch orangutans as they play with computer touch screens.
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Michael McCabe IIIFaculty of Archaeology
m.d.mccabe.iii@arch.leidenuniv.nl | 071 5272727
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Arnout KoornneefFaculty of Social and Behavioural Sciences
a.w.koornneef@fsw.leidenuniv.nl | 071 5271861
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Tessa VerhoefFaculty of Science
t.verhoef@liacs.leidenuniv.nl | 071 5277903
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Marina TerkourafiFaculty of Humanities
m.terkourafi@hum.leidenuniv.nl | 071 5273159
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Arie VerhagenFaculty of Humanities
a.verhagen@hum.leidenuniv.nl | 071 5272727
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Veronica Janssen
Faculty of Social and Behavioural Sciences
vjanssen@fsw.leidenuniv.nl | 071 5272727
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David HeyneFaculty of Social and Behavioural Sciences
heyne@fsw.leidenuniv.nl | 071 5272727
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Developmental and Educational Psychology Lab
What is the relation between brain development and social and cognitive development across childhood, adolescence and adulthood?
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Research
The main focus of our research programme is on adolescence, a key transitional period in human development. The programme puts emphasis on combined experimental behavioural and neural analysis of normative transitions and deviations in adolescent development.
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Leiden Index of Depression Sensitivity
The Leiden Index of Depression Sensitivity (LEIDS) measures cognitive reactivity (CR) to sadness, an aspect of cognitive vulnerability to depression, conceptually similar to rumination.
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On the representation of quantity: how our brains shape language
This project investigates properties of quantity expressions across languages from the perspective of how quantity is represented in the human brain.
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Research Seminars
The Psychology Research Seminars are organised by and for institute staff. They offer an opportunity to share knowledge, gain new insights, and meet colleagues from various disciplines.
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Grip krijgen op complexiteit. Onderwijs voor het 'moeras' - Getting a grip on complexity. Education for the 'swamp'
How can pupils and students learn to get a grip on complex 'swamp situations'? Inaugural lecture in abbreviated form held by prof.dr.ir. Fred Janssen on the acceptance of the post of professor of science education at Leiden University on 19 June 2017.
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Leticia Rettore MicheliFaculty of Social and Behavioural Sciences
l.rettore.micheli@fsw.leidenuniv.nl | 071 5272727
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Research
Our research examines mental health risk and resilience in young people. We do so by integrating cultural, social, cognitive and neurobiological factors and their interactions.
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Admission and Application
Are you interested in studying the Cognitive Neuroscience research master's programme at Leiden University? Find out how to apply by following the step-by step guide in the application and admission section.
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Members
The Leiden Institute for Brain and Cognition is a network that stimulates interdisciplinary exchange of knowledge and expertise on topics related to brain and cognition and focuses on science valorisation and outreach. Its research members come from a broad and diverse spectrum of specialized academic…
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Special training and testing reveal children's potential for learning
Traditional school tests, like the Dutch CITO, largely reflect students' existing knowledge and abilities. However, dynamic testing sheds light on students' learning potential, discovered Mirjam de Vreeze in her PhD research. This approach is especially promising for children with learning challenges,…