576 search results for “genome organisation” in the Public website
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Feodor-Lynen research fellowship for Bela Bode
Dr Bela Bode receives a Feodor Lynen research fellowship for postdoctoral researchers by the Alexander von Humboldt-Foundation for development of new methods for signal enhancement in solid state NMR. He aims to create a specific analytical tool for surface studies and research on membranes and membrane…
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Ten years of Life Science and Technology
On September 9th 2009, the study Life Science and Technology (LS&T) celebrates its 10th anniversary. In 1999, a group of enthusiastic pioneers within the Technical University Delft (TUD) and Leiden University (LU) founded a novel study based on the biotechnological expertise of research institutes within…
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Preventing or curing diseases with X-omics
In April, the X-omics initiative was granted 17 million euros from the Dutch Organization for Scientific Research. The subsidy is part of the National Roadmap for large-scale scientific infrastructure, intended to build or renew large-scale research facilities. What new insights will this investment…
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IBL symposium “Integrative Biology towards Healthy Communities”
On Monday the 8th of December, the annual symposium of the IBL will be organized at the main building of the LUMC Leiden. This year’s theme is “Integrative Biology towards Healthy Communities”.
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Zebrafish models for disease and environmental stress
We use zebrafish as a model organism to study human development and disease as well as animal welfare and environmental impact.
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Vici grants for three Leiden researchers
Three Leiden researchers have been awarded a prestigious Vici grant, the Dutch Research Council (NWO) announced on Tuesday. Two of the researchers work at Leiden University and the third at the Leiden University Medical Center (LUMC).
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Discourse change in international organizations: How UN peace operations respond to global normative change and shifting power distributions
Buitelaar argues that IOs micro-level discourse adapts imperfectly to macro-level changes, balancing adaptation to pressures with commitment to values.
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Overview
The Division of Systems Pharmacology and Pharmacy (SPP) aims to develop precision medicine approaches to characterise and predict variation in treatment response and enhance translational drug development strategies.
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No venom resistance in snake-eating birds: ‘They just don’t need it’
To eat or get eaten. It describes the evolutionary race of snakes versus the mammals and birds that prey on these snakes. Muzaffar Ali Khan devoted his PhD to investigating the molecular mechanisms play of the evolutionary arms race, and has his promotion 16 February. What makes mammals and birds successful…
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Soil bacteria can produce a wealth of new antibiotics
Soil bacteria can produce a wealth of antibiotics that are new to us, claims Gilles van Wezel, Professor of Molecular Biotechnology at the Institute of Biology Leiden. His research group has developed a method that can rapidly identify and produce these unknown compounds.
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This week the National Antibiotic Development Platform, NADP, was officially launched via a meeting in Utrecht.
Antibiotic resistance is one of the major threats to human health. This week the National Antibiotic Development Platform, NADP, was officially launched via a meeting in Utrecht, with many of the stakeholders in the field present.
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Embryos of the bitterling perform a somersault. This teaches us something new about natural selection
Even embryos can become embroiled in an evolutionary arms race with another species. Leiden biologists demonstrate this with larvae of the rosy bitterling that parasitize the gills of freshwater mussels. They published their research on February 19 in PNAS.
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Snake venom glands grown in lab
For the first time, researchers were able to grow organoids from snake venom glands. The lab-grown 3-D structures can produce snake venom molecules. This is a major step in finding treatments to tackle snakebite, which causes over 100,000 deaths each year. Publication in top journal Cell.
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New insights into evolutionary loss of digits
Merijn de Bakker and colleagues of the IBL-research group of Prof. Mike Richardson provide a unique view on digit evolution in crocodiles and birds in their recent study published in Nature.
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Science and business working together on affordable alternatives for antibiotics
Almost fifty scientists and twenty companies will be working on developing new antibiotics and alternatives for antibiotics use. NWO and the Ministry of Health, Wellbeing and Sport will together invest close to seven million euros in this research. Scientists from Leiden University and LUMC will be…
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Alumnus Robert Ietswaart: ‘Machine learning is revolutionising drug discovery’
Robert Ietswaart does research into gene regulation at the famous Harvard Medical School in Boston. He developed an algorithm to better predict whether a candidate medicine is going to produce side effects. He studied mathematics and physics in Leiden, and gained his PhD in computational biology in…
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Virologist Eric Snijder: ‘Vaccination will be going well in 2021’
The research group of Eric Snijder, Professor of Molecular Virology (LUMC), has been conducting research on coronaviruses for decades. Then in March this year their work accelerated at an unprecedented rate. The first new results are now available: insight into how the virus replicates.
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When will there be a coronavirus vaccine?
The genetic code of the new coronavirus has been found: it is closely related to the SARS virus from 2003. Professor of Molecular Virology, Eric Snijder, has been researching coronaviruses for years. We asked him a few questions about the outbreak. ‘It’s still unclear whether this new virus is more…
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Are Citizens More Negative About Failing Service Delivery by Public Than Private Organizations?
Petra van der Bekerom, Joris van der Voet, and Johan Christensen, three assistant professors at Leiden University, conducted a large-scale survey experiment about whether citizens are more negative about failing service delivery than private organizations.
- Managing the nuclear threshold: Non-nuclear allies in NATO decision-making
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Special Chair Organised and Subversive Crime Studies
Starting 1 July 2020, Pieter Tops will hold the special chair Organised and Subversive Crime Studies. The chair will be hosted by the Institute Security and Global Affairs (ISGA) at Leiden University's Faculty Governance and Global Affairs. Pieter Tops is a lector at the Police Academy. He conducts…
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25 million euros for research into energy from plants and algae
On Friday 10 July the Towards Biosolar Cells research programme was granted a budget of 25 million euros by the Dutch Government. The Ministry of Agriculture, Nature and Food Quality recommended the programme because it will contribute to green energy, improve food supplies and a create a more sustainable…
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ERC grant to improve post-vaccination protection in low-income countries
Maria Yazdanbakhsh, Professor of Parasitology at the Leiden University Medical Centre (LUMC), has been awarded an ERC Advanced Grant of 2.5 million euros. She will investigate why people in Africa and Southeast Asia respond less to certain vaccines than Europeans. Her goal is to find a solution for…
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Failures at foster care organisation Enver confirmed
The Dutch Health and Youth Care Inspectorate (IGJ) has found that foster care at stitching Enver is not up to scratch. Mariëlle Bruning, Professor of Children and the Law, spoke to public broadcaster NOS about these new findings.
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‘Don’t ever discriminate yourself by any gender-related label’
Iranian molecular plant biologist Salma Balazadeh started her career in Germany. Now she sets up a research group in Leiden to study stress in plants to secure global food supply. Her outlook on women in science in the context of the International Day for Women and Girls in Science, 11 February.
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Visit the Leiden preliminary heat of FameLab
Which two Leiden scientists will present their research in the most compelling way in three minutes? It could be those with the most supporters. The Leiden preliminary heat of FameLab is taking place on 14 February. Sign up now to be in the audience!
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New funding for advanced microscopy using gold nanorods
A consortium of researchers from the Leiden Institute of Physics (LION), the Institute of Biology Leiden (IBL), and the Leiden Institute of Chemistry (LIC) received a FOM program grant to develop a novel way of studying individual proteins inside a cell using gold nanorods.
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26 million for research into the impact of non-genetic factors on health
Who will be affected by certain chronic diseases, and who will not? For 30 percent that depends on heredity factors, whereas no less than seventy percent is explained by external factors. A Dutch research consortium receives 18 million euros from the prestigious Zwaartekrachtsubsidies to study these…
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‘Using real-world data to enhance our healthcare system’
On 16 May 2022, Professor Michel Wouters from the Department of Biomedical Data Sciences at the Leiden University Medical Centre (LUMC), will deliver his inaugural lecture titled ‘Quality of Cancer Care: why the real world matters’. Wouters will use the opportunity to describe how quality registries…
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The African lion consists of two subspecies
Biologist Laura Bertola argues that the traditional separation of lions into African and Asian subspecies is incorrect. She has discovered that Africa is actually home to two subspecies. Her PhD defense was on 18 March 2015.
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New insights into chemical sensing of the human pathogen for cholera
The bacterium Vibrio cholerae is a serious threat to our health because it is the causative agent of cholera. Worldwide, over a billion people per year are at risk of cholera infection. New strains of V. cholerae are resistant to the multiple drugs used to treat cholera, meaning that new types of drugs…
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Second layer of information in DNA confirmed
Leiden theoretical physicists have proven that not only the genetic information in DNA determines who we are, but also DNA’s mechanics. Helmut Schiessel and his group simulated many DNA sequences and found a correlation between mechanical cues and the way DNA is folded. Publication in PLoS One.
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EUROTAST Press Release
The transatlantic slave trade between the 15th and 19th centuries represents one of the most traumatic chapters in history and is now widely recognised as a crime against humanity. EUROTAST is a new European-funded research network that will bring together an unprecedented range of researchers to examine…
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AI, Healthcare, and the Law Panel at CPDP 2020
On 24 January 2020, eLaw attended the Annual Conference on Privacy and Data Protection (CPDP) in Brussels, Belgium. The overarching theme of the 13th edition was
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Three Leiden scientists receive NWO ENW-KLEIN grant for innovative research
The origins of Surinamese rice, a digital twin of the Earth and a large big-data project in the Chilean sky: three Leiden scientists receive an ENW-KLEIN grant for innovative, fundamental research.
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European roadmap for graphene applications in science and technology
More than 60 European researchers and industry partners have set out their roadmap for the application of graphene in marketed products. Leiden chemist Grégory F. Schneider believes that graphene and other layered materials can in the future be used for DNA sequencing applications.
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Non-invasive DNA-labeling tool opens doors for new research
Dutch researchers have developed a new tool to label DNA for studying chromosomes in live cells. The tool is non-invasive and can be applied in culture but also in living organisms, such as zebrafish embryos. The team published their findings in the journal Nucleic Acids Research.
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Altruism in bacteria: colonies divide the work
Bacteria found in soil specialise in the colony by division of labour. Some of the bacteria produce antibiotics, even when it comes at the expense of their individual reproduction success, to defend their colony against competitors. Publication in Science Advances.
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Seven new Medical Delta professors
Medical Delta has appointed seven professors who will bridge the medical worlds of Leiden, Delft and Rotterdam.
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ERC grant for Sebastian Pomplun to precisely influence gene expression
In order to stop a whole range of diseases or disorders at their source, you would have to be able to switch certain genes on or off. Sebastian Pomplun wants to develop substances that can do this very precisely. For example, he wants to disrupt cancer processes and make cells produce an important missing…
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Over a million euros for two studies on solutions to antimicrobial resistance
Two consortia led by Leiden researchers have been awarded over one million euros by the Dutch Research Council and the Ministry of Health, Welfare and Sport to find solutions to antimicrobial resistance.
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Leiden’s poo can help rid patients of resistant gut bacteria
Transferring poo from healthy donors to the intestines of chronically ill people has beneficial effects on these recipients’ gut bacteria, also in the longer term. This is the conclusion of research by the Leiden University Medical Center (LUMC) and the Netherlands Donor Feces Bank (NDFB).
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'Biologists also need to be a bit of a data analyst’
Biologists today have to be able to work with big data. Data analysis skills should be taught from the start of the degree programme, or - even better - in secondary school. This is the message of Vera van Noort, new Professor of Computational Biology. Inaugural lecture 22 January.
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Bacteria full of potential: searching for new antibiotics through genetic on–off switches
Collaborating and learning from other fields – that is what bioinformatician Hannah Augustijn enjoys most about doing research. During her PhD at Leiden University, she developed new ways to search within bacteria for the antibiotics of the future.
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Academics call for more powers for international organisations
Organisations like the UN and the EU should be given more powers to combat transboundary problems. This is the message of a report published by the Swedish SNS Democracy Council, whose authors include Prof. Jan Aart Scholte of Leiden University. The researchers also wrote the following article.
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NWO grant for research on new type of global organisation
To what extent can global issues be solved by multistakeholder collaboration, a relatively new type of organisation? Jan Aart Scholte, the coordinator of the Global Transformations and Governance Challenges (GTGC) interdisciplinary research programme, has received a Dutch Research Council (NWO) grant…
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Managers play an important role in inclusiveness in organisations
Team leaders and other immediate supervisors play an important role in facilitating inclusiveness within public organisations. This is the finding of research by public administration expert Tanachia Ashikali. PhD defence 20 November.
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Erwin Muller appointed Vice-Rector of Organisational Development
Leiden University’s Executive Board has appointed Erwin Muller as Vice Rector of Organisational Development. In this role, he will help further professionalise and improve the university’s organisation as per the Strategic Plan.
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University and government organisations to work together on public leadership
How adaptable can and should a government organisation be – in a crisis situation, for instance? How can such organisations join forces to solve the problems faced by citizens? Leiden University will collaborate with six government organisations that are opening their doors for research and the joint…
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Organisations often learn too little from disasters and crises
From recurrent oil disasters to the outbreak of contagious diseases or major fires. Public organisations often learn too little from such crises, according to public administration specialist Wout Broekema. Staff frequently fail to communicate information adequately, which means that lessons are often…