1,226 search results for “lysosomal state disorders” in the Public website
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On electronic signatures of topological superconductivity
Promotor: Prof.dr. C.W.J. Beenakker
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On transport properties of Majorana fermions in superconductors: free & interacting
Majorana fermions in superconductors are the subgap quasiparticle excitations that are their own antiparticles.
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Executive deficits in relation to early reading and math development
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Military Artificial Intelligence and the Accountability of States and Individuals for Crimes against Humanity in the Ukraine
Tens of thousands of soldiers and civilians have died as a result of Russia’s invasion of Ukraine in February 2022 and the continuing armed conflict. Many forms of critical infrastructure have been destroyed. Much of this devastation has been caused by weapons that utilise forms of artificial intelligence…
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Degradome analysis of vaccines
The objective is to develop in vitro antigen degradation assays in order to mimic the fate of the antigen in vivo.
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Iminosugars as glucosylceramide processing enzymes inhibitors: design, synthesis and evaluation
This Thesis describes the design, synthesis and evaluation as glycoprocessing enzyme inhibitors of focused libraries of iminosugars.
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New handbook “EU State Aids”
The Europa Instituut is pleased to announce that this week a new handbook “EU State Aids” (31 Chapters, 1500 pages) was published.
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Voluntary, Non-Binding Norms for Responsible State Behaviour in the Use of Information and Communications Technology: A Commentary
The United Nations Office for Disarmament Affairs (UNODA) has published the 2017 issue in their Civil Society and Disarmament series, titled Voluntary, Non-Binding Norms for Responsible State Behaviour in the Use of Information and Communications Technology: A Commentary. The series aims to provide…
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Borders and Mobility Control in and between Empires and Nation-States | Studies in Global Migration History, Volume: 46/14
In a modernist interpretation of migration controls, nation states play a major role. This book challenges this interpretation by showing that comprehensive migration checks and permanent border controls appeared much earlier, in early modern dynastic states and empires, and predated nation states by…
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Severe behavioral and emotional problems, special education and youth care
Which educational and child welfare interventions offer optimal opportunities for positive development to children with severe behavioral and emotional disorders.
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Social Injustice, Disadvantaged Offenders, and the State’s Authority to Punish
Andrei Poama, Assistant Professor at Leiden University, published a piece in the journal of Political Philosophy about social injustice, disadvantaged offenders and the state's authority to punish.
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Privilege, Economy and State in Old Regime France: Marine Insurance, War and the Atlantic Empire under Louis XIV
This book closely analyses the rise and fall of Louis XIV's marine insurance institutions in Paris, which were central to the French monarchy's efforts to stimulate commerce, colonial enterprise and economic growth.
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Politics, pandemics, and support: the role of political actors in Dutch state aid during COVID-19
How do governments distribute resources across economic sectors during a crisis? And why do some sectors receive more than others? The recent COVID-19 pandemic has highlighted the urgency of these questions. In this paper, we explore the extent to which a political economy…
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Importance of Religion in Spinoza's Thought and Its Implications for State and Society
On 23 October 2019, Yoram Stein defended his thesis 'Spinoza's Theory of Religion: The Importance of Religion in Spinoza's Thought and Its Implications for State and Society'. The doctoral research was supervised by Prof. P.B. Cliteur and Prof. A.A.M. Kinneging.
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Abdourahamane Idrissa AbdoulayeAfrican Studies Centre
a.idrissa.abdoulaye@asc.leidenuniv.nl | +31 71 527 3372
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Willemien den OudenFaculty of Law
w.denouden@law.leidenuniv.nl | +31 71 527 --
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Anne Hafkemeijer
Social & Behavioural Sciences
a.hafkemeijer@fsw.leidenuniv.nl | +31 71 527 1375
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Studies on molecular basics of metabolic syndrome in zebrafish
The research described in this thesis has, using the zebrafish as a model system, shed new light on the intricate relationship between TB and DM2, in particular on the role of leptin, SHP-1 and glucocorticoids.
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Nienke BouwSocial & Behavioural Sciences
j.c.bouw@fsw.leidenuniv.nl | +31 71 527 2727
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Linguistic and Cultural Foreign Policies of European States
The policies relating to language pursued by European monarchies and states have been widely studied, but far less attention has been given to their linguistic and cultural policies in territories outside their own borders.
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Cohen, The Right-Wing ‘One-State Solution’
Mateo Cohen (research assistant at the Open University of Israel and PhD candidate at Leiden University’s Institute of Political Science) studied arguments articulated by diverse members of the Right-Wing elite in Israel and explains how these views lead to the rejection of a two-state solution and…
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Technology and the State: Enlightenment Language Machines, Then and Now
Lecture, Research Seminar Medieval and Early Modern History
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Catecholamine function, brain state dynamics, and human cognition
The work presented in this thesis addresses the role of the locus coeruleus (LC) - norepinephrine (NE) system in various aspects of human cognition, and the modulation of brain state.
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The Power of Words: State Reactions to Protest Announcements
Organizations often announce their protest activities prior to their implementation to mobilize awareness, recruit supporters, and receive media attention. We are interested in the effectiveness of protest announcements—that is, under what conditions governments make concessions to avoid having an announced…
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Semiha AydinSocial & Behavioural Sciences
s.aydin@fsw.leidenuniv.nl | +31 71 527 2727
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Isabella BrunnerFaculty of Governance and Global Affairs
i.brunner@fgga.leidenuniv.nl | +31 70 800 9500
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Neurodevelopmental risks in young children with an extra X or Y chromosome
This longitudinal study is focused on neurodevelopmental problems in young children with XXY, XXX and XYY, aged 1 to 6 years.
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Protection of Environmental Refugees. A human rights-based, security and State responsibility approach
On 7 May 2020, Jolanda van der Vliet defended her thesis 'The International Legal Protection of Environmental Refugees. A human rights-based, security and State responsibility approach'. The doctoral research was supervised by Prof. N.J. Schrijver and Prof. J.J.C. Voorhoeve.
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The political economy of immigration and welfare state reform: a collection of comparative political and economic essays on human mobility and
On 12 November, Clare Fenwick defended her doctoral thesis, The Political Economy of Immigration and Welfare State Reform: A Collection of Comparative Political and Economic Essays on Human Mobility and Social Protection. The PhD research was supervised by Olaf van Vliet and Kees Goudswaard.
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Bioclock: Light therapy for depression
Optimization, mechanisms of action and predictors of the outcome of light therapy in depression: A multicenter randomized trial
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Lipidomics study in liver metabolic diseases
The ideas underlying this thesis are that lipidomics may improve the diagnosis of liver metabolic diseases, and can provide further insights into the underlying pathophysiology of these diseases.
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Quantitative Super-Resolution Microscopy
Promotor: T. Schmidt
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Regulation of autophagy-related mechanisms during bacterial infection
Autophagy is a fundamental degradative process, maintaining cellular homeostasis and functions in host defense against intracellular pathogens, including mycobacteria and Salmonella.
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Selective autophagy in host defense against mycobacterial infection
The effective treatment of tuberculosis (TB) remains a major challenge to global health.
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Autophagy and Lc3-associated phagocytosis in host defense against Salmonella
Control of infectious diseases poses continuous challenges for human health.
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Bioorthogonal Labeling Tools to Study Pathogenic Intracellular Bacteria
In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.
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Gold nanoparticle-peptide conjugates for biomedical applications
Despite the fact that gold nanoparticles (GNPs) are one of the most studied nanoparticles, there is still a necessity for new approaches allowing for effective protective coating to enable wider use of GNPs in biomedical applications.
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Exploring chemical space in covalent and competitive glycosidase inhibitor design
Glycoside hydrolases (glycosidases/GHs) are widely abundant enzymes in all kingdoms of life and are important biocatalysts that catalyze the hydrolysis of glycosidic linkages in oligo/polysaccharides, glycoproteins and glycolipids with tremendous efficiency
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Jeffrey Fynn-PaulFaculty of Humanities
j.fynn-paul@hum.leidenuniv.nl | +31 70 800 9191
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Worlding America: How Play Shaped the United States between New Media and New Politics
WORLDING AMERICA researches how ‘play’ has been a key force in the past and present process of creating America as a coherent and hegemonic ‘world,’ from 1503 to the present.
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Online radicalisation: the use of the internet by Islamic State terrorists in the US (2012-2018)
Is online radicalisation is an analytically useful concept when discussing contemporary cases of terrorism?
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The Role of the Domestic Law of the Host State in Determining the ratione materiae Jurisdiction of Investment Treaty Tribunals: The Partial Revival
On 19 December 2019, Reza Eftekhar defended his thesis 'The Role of the Domestic Law of the Host State in Determining the ratione materiae Jurisdiction of Investment Treaty Tribunals: The Partial Revival of the Localisation Theory'. The doctoral research was supervised by Prof. E. de Brabandere.
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Face-to-face politics: why small states matter
Political scientist Wouter Veenendaal received an NWO Veni grant for his research on the political stability of small states. 'I find small states fascinating, they are almost always excluded from comparative research, while in fact they often challenge existing theories in political science.'
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Contribution to international book on enforcement of State aid law
In January 2020 the book “Private Enforcement of European Competition and State Aid Law”, edited by Ferdinand Wollenschläger, Wolfgang Wurmnest & Thomas M.J. Möllers, was published by Wolters Kluwer.
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Manja KoendersSocial & Behavioural Sciences
m.a.koenders@fsw.leidenuniv.nl | +31 71 527 7980
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Evert Scholte
Social & Behavioural Sciences
e.m.scholte@fsw.leidenuniv.nl | 071 5272727
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Bianca BoyerSocial & Behavioural Sciences
b.e.boyer@fsw.leidenuniv.nl | +31 71 527 2727
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Special education and autism
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Development of visual span in Hebrew and Dutch-speaking prereaders
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Growth and Transport properties of (Rare Earth)TiO3 / SrTiO3 interfaces
This thesis presents the results of a study on the interfaces of insulating oxides with and without the insertion of a magnetic layer.