571 search results for “drug” in the Staff website
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Alive or not? Tiny 3D printed robots that swim and navigate just like animals
They are only a few tens of micrometres long — far smaller than the width of a human hair – yet these robots can swim, sense, navigate and adapt in ways that look surprisingly life-like. And all this without having a brain.
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From lab to startup: scientist develops new treatment for nerve pain
What do you do when a discovery in the lab shows real promise? Scientist Mirjam Huizenga founded a startup to develop a new treatment for nerve pain caused by chemotherapy. ‘The goal is to give patients a better option.’
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Teams formed to lead university themes
The teams that will lead the themes guiding Leiden University’s strategic positioning in the coming years have been formed.
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These were Leiden University’s interdisciplinary milestones of 2024
Connecting scientific fields, enhancing research and teaching, and providing innovative solutions to complex social issues: that is the idea behind interdisciplinary research. What did the university achieve in 2024? A small sample.
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Mutation-Driven Modulation of GPCR Pharmacology: Insights from Adenosine and Serotonin Receptors
PhD defence
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CellEKT: a chemical proteomics platform to study the kinome
PhD defence
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Microphysiological liver systems for in vitro modeling and industry implementation
PhD defence
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Acquired resistance in pancreatic cancer: characterization and exploration of actionable targets of a multifactorial disease
PhD defence
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E-Values for Anytime-Valid Inference with Exponential Families
PhD defence
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New traffic controller discovered on DNA railway
A new LUMC study has changed our understanding of how cells work. Researchers have discovered that the CFAP20 protein acts as a kind of ‘traffic controller’ on DNA. Without this protein, chaos ensues, potentially causing cancer. Their findings have been published in the prestigious journal Nature.
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Turning the tables on tuberculosis: boosting our own immune forces
Tuberculosis bacteria survive by hiding in our immune cells. In her PhD research, biologist Salomé Muñoz Sánchez explores how boosting the body’s own defenses might outsmart this deadly pathogen. Her work reveals two key proteins that help immune cells destroy the bacteria.
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Organising STEM effectively, both within and beyond the faculty
Tuesday 27 January - A crisp winter morning and a busy Tuesday. Board matters, research safety, leadership and faculty profiling alternate throughout the day, with a focus on collaboration both inside and outside the faculty. A full day that ends with a game of darts.
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New statistical method brings together studies at an early stage
During the coronavirus pandemic, scientists were in a hurry to find drugs that would help fight the disease. To combine the research that was being carried out around the world, PhD candidate Judith ter Schure developed a new statistical method: ALL-IN meta-analysis. This helps determine sooner whether…
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Using low sample volumes to better understand brain diseases
Marlien van Mever delved into the analysis of tiny samples, cerebrospinal fluid from transgenic mouse models for example. She validated methods that can now be used to study brain diseases such as migraine and epilepsy. Van Mever will receive her PhD on 14 June.
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Jasper’s day - from Leiden to Brussels to Voorschoten
On Monday, 13 October, Jasper will travel to Brussels with a delegation from Key Region Leiden. Why is this collaboration important? And who will he be having dinner with that same evening in Voorschoten? Jasper shares his account of a long and interesting Monday.
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Smart monitoring of test subjects is the future of clinical research
Knowing whether or not a treatment is working just by wearing your watch? Data scientist Ahnjili ZhuParris has identified a lot of opportunities for the use of machine learning in clinical research to monitor test subjects at home.
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Jasper's Day
Jasper Knoester is the dean of the Faculty of Science. How is he doing, what exactly does he do and what does his day look like? In each newsletter, Jasper gives an insight into his life.
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‘Exposure therapy’ for bachelor students: preparing for the reality of scientific research
Already during their bachelor’s programme, students in Pharmaceutical Sciences are presented with challenging projects. One of these is the Bachelor Research Assignment (BOO in Dutch), which is often their first real experience with scientific research. This means a lot of responsibility and failures,…
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Veni grant for ten Leiden researchers
Ten Leiden researchers have been awarded a Veni grant by the Dutch Research Council (NWO). The grant, of up to 280,000 euros, will enable them to elaborate their ideas over a period of three years.
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Biological Origami at molecular level: folding a single protein
Human cells are protecting their proteins from unfolding and aggregating. That's what biophysicist Alireza Mashaghi and his team discovered after seven years of in-depth research into the folding mechanisms of proteins. With an unprecedented approach, the team was able to study the folding of a single…
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Flu stops when you block the enzyme that cleaves off virus particles
A flu virus could cause a pandemic. And then we would be poorly armed because flu viruses are starting to become resistant to flu medications like Tamiflu. Chemist Merijn Vriends successfully worked on an improved version of such medications. He will be awarded his doctorate on September 12th.
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Minor Violence Studies: interesting encounters and flying wooden blocks
The English taught interdisciplinary minor Violence Studies looks into various facets of interpersonal violence. Is this minor for all Leiden students? These two 'colleagues' are certain of it.
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Pride is a celebration, but also a fight for visibility
‘Be yourself. Be as gay, queer, trans as you can and show the world you exist.’ These rousing words from Looi van Kessel marked the start of the third Pride Leiden for the university boat, with the theme: ‘450 years of being yourself’.
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GTGC lunch seminar series: an international, interdisciplinary scope
Starting February 6, the Leiden interdisciplinary research programme Global Transformations and Governance Challenges (GTGC) will host a lunch seminar series on pressing global governance issues. The series will feature researchers from various disciplines. It promises to be a trove of inspiration and…
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Awaken sleeping antibiotics with ERC Advanced grant
To facilitate the search for new antibiotics. That is the aim of Gilles van Wezel, professor molecular biotechnology at the Institute of Biology Leiden (IBL). He wants to do this by looking at similarities in the DNA of antibiotic-producing bacteria. Van Wezel has been awarded an ERC Advanced grant…
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How to make cryptographic techniques more efficient?
Sharing scientific data, transferring money, or sending other sensitive information online: with cryptography, applications make sure your data does not fall into the wrong hands. Mathematician Thomas Attema (CWI/TNO/Leiden University) helps with this. For his PhD research, he developed a new technique…
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How NeCEN helped develop the Johnson & Johnson Covid-19 vaccine
The Phase 3 clinical trial results of the promising Covid-19 vaccine of Johnson & Johnson are expected this month. The Dutch electron microscopy facility NeCEN helped develop the company’s vaccine, and they have now published their scientific findings in Nature Communications.
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Contributing to cancer research in your own way: three PhD candidates on their work within Oncode Accelerator
Accelerating the development of new cancer medicines by joining forces—that’s the mission of Oncode Accelerator, a Dutch consortium that recently welcomed three Leiden-based PhD candidates. Under the guidance of Gerard van Westen, Marc Boef, Remco van den Broek, and Lucina-May Nollen are exploring how…
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'Satisfied students give me more fulfillment than getting a research grant'
Imparting students with a critical attitude and cross-curricular skills. That is what Rawi Ramautar wants to strive for as the new programme director (OD) of the bachelor of Bio-Pharmaceutical Sciences. 'A programme director has to create a programme of which students say: I find it challenging and…
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Curing diseases with lab-grown organs
Organs and tissues grown in the lab may in the future be able to cure people with organ failures. Micha Drukker, professor of Stem Cells, Developmental Biology and Technology for Innovative Drug Research, is convinced that the use of stem cells will make this possible. He will deliver his inaugural…
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Status update in the evolutionary race between humans and resistant bacteria: two steps forward for us
A patent for what may be a potent, new antibiotic. And: a clear overview of promising approaches to overcome a crucial resistance tactic employed by bacteria. In the span of one week, two researchers from Leiden are receiving their PhDs, each of them on an important step in the battle against bacteria…
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LUMC signs international agreement on developing Advanced Therapy Medicinal Products
Skåne University Hospital, Lund University and Leiden University Medical Center will work together to expand their research, teaching and development relating to Advanced Therapy Medicinal Products. That is the essence of a Memorandum of Understanding signed at SciLifeLab near Stockholm on Wednesday…
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Organ failure caused by viruses, how does it work? Now there are methods to find out
Dying from viral infection due to organ failure and blood loss: we still know little about how it can happen. Among other things, Huaqi Tang developed an organ-on-a-chip to figure it out. 'These technologies can offer unprecedented opportunities to fight the viruses that threaten our society.' Tang…
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Join us at 3 October University and the Weekend of Science
Are you curious about how the human skeleton works? Discover this and more on 3 October in Leiden and on 4 October in The Hague.
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Leiden University academics pursue international projects with Una Europa grants
Seven interdisciplinary projects involving Leiden University academics have been awarded up to €27,000 in seed funding. They will work with Una Europa alliance partners to advance topics including academic freedom, AI in the humanities, sustainable mining and maternal health care.
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With 30 million dollars, this consortium aims to tackle tuberculosis
Thanks to a clever research method, progress is being made in the quest for better tuberculosis medications. Within an American consortium that received a 30 million dollars grant, Leiden researcher Rob van Wijk plays a significant role. ‘The next breakthrough in tuberculosis research will come much…
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Post-quantum cryptography should keep our DigiD, bank accounts and state secrets safe
Our banking, DigiD and sensitive medical data: what if our entire digital infrastructure can no longer be trusted? Jelle Don has this question permanently in mind as he goes about his research. And that is no bad thing because without new digital security measures, our society will be extremely vuln…
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Small actions by our labs add up to big steps in sustainability
Freezers set three degrees higher, a recycling bin for plastic petri dishes or timer switches installed on equipment: a growing number of Leiden University laboratories are taking small – but effective – steps to reduce their environmental impact, via the internationally recognized Laboratory Efficiency…
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LIFES: From Reusable Data to New Treatments and Faster Diagnoses
Early diagnosis, new treatments, and personalised care: all of these are possible if we can better unlock the wealth of information hidden in health data. Unfortunately, this data is often poorly organised, difficult to access, and not interoperable. The new international Leiden Institute for FAIR and…
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‘Ultimately, the goal is to develop antibiotics for tuberculosis with a lower risk of resistance’
Tuberculosis stands as one of the most lethal infectious diseases worldwide. A significant challenge in combatting tuberculosis lies in the emergence of antibiotic resistance triggered by genetic alterations, commonly known as mutations. These mutations can diminish the responsiveness to antibiotics,…
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Smart programming for the quantum computer that does not exist yet
Designing innovative algorithms, thinking outside the box, and brainstorming over coffee with his colleagues — this is what physicist Stefano Polla enjoys most. His success shines through in his nomination for the C.J. Kok Jury Award 2024 for PhD thesis of the Year.
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Room for everyone at a sun-drenched EL CID
Thousands of first-year students and hundreds of mentors kicked off the EL CID on Monday morning. This year for the first time, the introduction week of Leiden University and Leiden University of Applied Sciences was also open for students of Regional Training Centre mboRijnland and the Leiden Instrument…
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Protecting the tiniest lives: how biological signals can improve care for premature babies
When a baby is born too soon, every minute counts – and so does every decision. To reduce uncertainty in those critical moments, biopharmaceutical scientist Manchu Umarani Thangavelu dedicated her PhD to identifying molecular markers of preterm birth and neonatal infection.
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Ine Tijdens on forty years at LACDR: ‘No two days were the same’
She walked into the Sylvius building as a wide-eyed twenty-something in 1984, and next year, she’ll be leaving us as a soon-to-be retiree in her sixties. Ine Tijdens (66) reflects on more than four decades at LACDR. ‘One year, I got a little whip for Sinterklaas. That says something about my persona…
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Academia in Motion: ‘Trying to do everything yourself is inefficient’
A stronger focus on personal talents and team science. ‘Stop searching for those elusive hen’s teeth: they’d only get in the way’, says Professor Laura Heitman about Academia in Motion. ‘It’s unrealistic to excel in everything.’
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Leiden biologists find nanoplastics in developing heart
Nanoplastics can accumulate in developing hearts, according to a study by biologist Meiru Wang from Leiden University. Her research on chicken embryos sheds new light on how these tiny plastic particles pose a threat to our health.
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Five Leiden contributions to NWO Perspectief projects
Five consortia within the Perspectief programme that include Leiden researchers have received funding to start their research projects. These projects focus on (further) developing technological innovations, with societal and economic impact at their core.
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Antibiotic Conjugates and Natural Products as Next-Generation Strategies Against Antimicrobial Resistance
PhD defence
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New Year's Reception
Conference
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Designing the next generation of precision medicine
Lecture, Tuesday Talks: Science Insights