490 search results for “anti-inflammatory drug” in the Staff website
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PhD Graduate Van Groesen: ‘Nothing is too crazy to try.’
In a world where bacteria are increasingly resistant to antibiotics, Emma van Groesen set out to find a solution. This month she obtained her PhD, after four years of research into new variants of the antibiotic vancomycin. With success.
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Artificial microswimmers work together like bacteria
Microscopic swimmers such as bacteria do not always swim alone. There are advantages to exchanging information and cooperating. Stefania Ketzetzi and colleagues now show in Nature Communications that human-made microswimmers, too, can cooperate.
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Biology student Martijn Verkuilen wins Unilever Research Prize
Martijn Verkuilen is the winner of the Unilever Research Prize 2022. By transferring DNA from a plant into yeast, he made the first move to produce a new drug for type 2 diabetes. He collected his prize in Wageningen on 24 November.
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Kiem project investigates link between violence and other health problems
‘Violence as a Population Health Problem’ is one of 33 interdisciplinary projects that have been launched thanks to a Kiem grant. The project team will analyse a large patient database to identify links between violence and other health problems. ‘Violence can also be an expression of other factors,’…
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Two new Directors for IBL
The Institute of Biology Leiden (IBL) has appointed two new directors. Maribel Adame Valero will become the new Director of Operations on 1 August, and Hubertus Irth will start as the new Scientific Director on 1 September. This completes the new collegial management for IBL, following the earlier appointment…
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Luijten appointed as Professor of Human-Relevant Risk Assessment of Chemical Substances
As of 1 July, toxicologist Mirjam Luijten from the Dutch National Institute for Public Health and the Environment (RIVM) starts as professor by special appointment at the Leiden Academic Centre for Drug Research (LACDR).
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Leiden researchers visualise the 'guardian of our genome’
The guardian of our genome, the protein MutS, scans the DNA for spelling errors and makes sure they are corrected. An essential process for our health. Researchers at Leiden University Medical Centre (LUMC) have discovered precisely how this protein works by making MutS visible with cryo-electron microscopy.…
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Researchers tackle antibiotic-resistant bacteria
When a bacterium becomes more resistant to one antibiotic, it sometimes becomes more sensitive to another. To better understand this interaction, researchers from the Leiden Institute of Biology (IBL) and the Leiden Academic Center for Drug Research (LACDR) under supervision of Daniel Rozen and Coen…
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Leiden scientists create first-ever dengue-on-a-chip to study this deadly virus
Researchers at Leiden University have created a unique model that mimics how disease develops after a dengue infection. This 'dengue-on-a-chip' model helps them study the virus more effectively. The timing is crucial, as climate change is causing dengue to spread worldwide.
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‘Sleep should play a greater role in lifestyle research’
Sleep disorders have a significant influence on our physical and emotional health. Sleep should therefore receive more attention within lifestyle medicine, says Professor Gert Jan Lammers. He will give his inaugural lecture on Friday 20 May entitled: ‘Getting to sleep’.
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De dag van Jasper
Jasper Knoester is de decaan van de Faculteit Wiskunde & Natuurwetenschappen. Hoe gaat het met hem, wat doet hij precies en hoe ziet zijn dag eruit? In elke nieuwsbrief geeft Jasper een inkijkje in zijn leven.
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Ecologist Michiel Veldhuis is the Discoverer of the Year 2020
Michiel Veldhuis received the most public votes for the C.J. Kok Public Award and may therefore call himself Discoverer of the Year. Veldhuis researches how climate change affects savannah ecosystems in Africa and how we can protect them.
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Three innovative research projects awarded Open Competition Science-M funding
Tracking mucus-eating bacteria, mapping the complexity of planetary nebulae and a signalling pathway in cancer. These three Leiden projects have been awarded Open Competition Science-M funding by the Dutch Research Council.
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Four Leiden researchers receive ERC Advanced Grant
From social inequalities in prehistory to placebo effects in medical treatments. Four researchers from Leiden University have been awarded a prestigious ERC Advanced Grant worth EUR 2.5 million to develop their research.
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Targeting the immune system to inhibit atherosclerosis
A new treatment for atherosclerosis showed promising results in isolated cells but proved to be less effective in initial animal tests. Bachelor student Biopharmaceutical Sciences Willemijn van der Heijden aimed to understand why. She investigated whether the formation of a protein layer around the…
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Executive Board column: Annetje Ottow on the importance of student associations
Now the introduction weeks can go ahead as usual, the new students’ enthusiasm is overwhelming. It’s back to normal for the student associations too, having had a hard time of it during the pandemic.
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Can we live longer? Leiden physicist makes discovery in protective layer in genes
With the aid of physics and a minuscule magnet, researchers have discovered a new structure of telomeric DNA. Telomeres are sometimes seen as the key to living longer. They protect genes from damage but get a bit shorter each time a cell divides. If they become too short, the cell dies. The new discovery…
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LUMC participates in pioneering type 1 diabetes research
The promising early results of an international study have shown that insulin-producing cells grown from stem cells can cure the disease. The new Cure One LUMC research centre aims to accelerate this breakthrough.
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Three awarded research projects in NWO-XS call
Cryogenic memories, antibiotic treatment for urinary tract infections and recycling plastic sustainably. These are the subjects of the three NWO-XS grants awarded to Leiden Science researchers.
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How do we get the we-feeling on the faculty? This is how Joost Batenburg thinks
As professor of computer science at LIACS and programme director of incentive programme SAILS, Joost Batenburg knows better than anyone what is going on in the faculty. Over the past three years, he learned at lightning speed what is going well and where sensitivities lie. 'We need to move more towards…
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BPS-student Ramazan Kiliç receives Travel Grant for Research Symposium in Baltimore, USA
This summer, one of our BPS-master students, Ramazan Kiliç, will travel to Baltimore to present his research at the annual ARRE Research Symposium, a conference on ASXL-disorders that attracts researchers from all over the world, including the US, Japan, Germany, Ireland and, of course, The Netherlands.…
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Quantitative Pharmacology Approaches to Inform Treatment Strategies Against Tuberculosis
PhD defence
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CellEKT: a chemical proteomics platform to study the kinome
PhD defence
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Microphysiological liver systems for in vitro modeling and industry implementation
PhD defence
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Exploration of the endocannabinoid system using metabolomics
PhD defence
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Optimizing antifungal treatment through pharmacometrics: dosing considerations for enhanced efficacy
PhD defence
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E-Values for Anytime-Valid Inference with Exponential Families
PhD defence
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Interdisciplinary collaboration in Leiden: discover the interdisciplinary research programmes
Event for all Leiden researchers
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Nathaniel MartinFaculty of Science
n.i.martin@biology.leidenuniv.nl | +31 71 527 2954
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Hermen OverkleeftFaculty of Science
h.s.overkleeft@chem.leidenuniv.nl | +31 71 527 5037
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Improving Nature’s Antibiotics to Overcome Resistant Bacteria
Lecture, NGL-lezing
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Organ failure caused by viruses, how does it work? Now there are methods to find out
Dying from viral infection due to organ failure and blood loss: we still know little about how it can happen. Among other things, Huaqi Tang developed an organ-on-a-chip to figure it out. 'These technologies can offer unprecedented opportunities to fight the viruses that threaten our society.' Tang…
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Curing diseases with lab-grown organs
Organs and tissues grown in the lab may in the future be able to cure people with organ failures. Micha Drukker, professor of Stem Cells, Developmental Biology and Technology for Innovative Drug Research, is convinced that the use of stem cells will make this possible. He will deliver his inaugural…
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Contributing to cancer research in your own way: three PhD candidates on their work within Oncode Accelerator
Accelerating the development of new cancer medicines by joining forces—that’s the mission of Oncode Accelerator, a Dutch consortium that recently welcomed three Leiden-based PhD candidates. Under the guidance of Gerard van Westen, Marc Boef, Remco van den Broek, and Lucina-May Nollen are exploring how…
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How NeCEN helped develop the Johnson & Johnson Covid-19 vaccine
The Phase 3 clinical trial results of the promising Covid-19 vaccine of Johnson & Johnson are expected this month. The Dutch electron microscopy facility NeCEN helped develop the company’s vaccine, and they have now published their scientific findings in Nature Communications.
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How to make cryptographic techniques more efficient?
Sharing scientific data, transferring money, or sending other sensitive information online: with cryptography, applications make sure your data does not fall into the wrong hands. Mathematician Thomas Attema (CWI/TNO/Leiden University) helps with this. For his PhD research, he developed a new technique…
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New statistical method brings together studies at an early stage
During the coronavirus pandemic, scientists were in a hurry to find drugs that would help fight the disease. To combine the research that was being carried out around the world, PhD candidate Judith ter Schure developed a new statistical method: ALL-IN meta-analysis. This helps determine sooner whether…
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Leiden University academics pursue international projects with Una Europa grants
Seven interdisciplinary projects involving Leiden University academics have been awarded up to €27,000 in seed funding. They will work with Una Europa alliance partners to advance topics including academic freedom, AI in the humanities, sustainable mining and maternal health care.
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Status update in the evolutionary race between humans and resistant bacteria: two steps forward for us
A patent for what may be a potent, new antibiotic. And: a clear overview of promising approaches to overcome a crucial resistance tactic employed by bacteria. In the span of one week, two researchers from Leiden are receiving their PhDs, each of them on an important step in the battle against bacteria…
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Awaken sleeping antibiotics with ERC Advanced grant
To facilitate the search for new antibiotics. That is the aim of Gilles van Wezel, professor molecular biotechnology at the Institute of Biology Leiden (IBL). He wants to do this by looking at similarities in the DNA of antibiotic-producing bacteria. Van Wezel has been awarded an ERC Advanced grant…
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Leiden biologists find nanoplastics in developing heart
Nanoplastics can accumulate in developing hearts, according to a study by biologist Meiru Wang from Leiden University. Her research on chicken embryos sheds new light on how these tiny plastic particles pose a threat to our health.
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Post-quantum cryptography should keep our DigiD, bank accounts and state secrets safe
Our banking, DigiD and sensitive medical data: what if our entire digital infrastructure can no longer be trusted? Jelle Don has this question permanently in mind as he goes about his research. And that is no bad thing because without new digital security measures, our society will be extremely vuln…
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With 30 million dollars, this consortium aims to tackle tuberculosis
Thanks to a clever research method, progress is being made in the quest for better tuberculosis medications. Within an American consortium that received a 30 million dollars grant, Leiden researcher Rob van Wijk plays a significant role. ‘The next breakthrough in tuberculosis research will come much…
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Flu stops when you block the enzyme that cleaves off virus particles
A flu virus could cause a pandemic. And then we would be poorly armed because flu viruses are starting to become resistant to flu medications like Tamiflu. Chemist Merijn Vriends successfully worked on an improved version of such medications. He will be awarded his doctorate on September 12th.
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Biological Origami at molecular level: folding a single protein
Human cells are protecting their proteins from unfolding and aggregating. That's what biophysicist Alireza Mashaghi and his team discovered after seven years of in-depth research into the folding mechanisms of proteins. With an unprecedented approach, the team was able to study the folding of a single…
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Smart programming for the quantum computer that does not exist yet
Designing innovative algorithms, thinking outside the box, and brainstorming over coffee with his colleagues — this is what physicist Stefano Polla enjoys most. His success shines through in his nomination for the C.J. Kok Jury Award 2024 for PhD thesis of the Year.
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Smart monitoring of test subjects is the future of clinical research
Knowing whether or not a treatment is working just by wearing your watch? Data scientist Ahnjili ZhuParris has identified a lot of opportunities for the use of machine learning in clinical research to monitor test subjects at home.
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Room for everyone at a sun-drenched EL CID
Thousands of first-year students and hundreds of mentors kicked off the EL CID on Monday morning. This year for the first time, the introduction week of Leiden University and Leiden University of Applied Sciences was also open for students of Regional Training Centre mboRijnland and the Leiden Instrument…
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Minor Violence Studies: interesting encounters and flying wooden blocks
The English taught interdisciplinary minor Violence Studies looks into various facets of interpersonal violence. Is this minor for all Leiden students? These two 'colleagues' are certain of it.
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LUMC signs international agreement on developing Advanced Therapy Medicinal Products
Skåne University Hospital, Lund University and Leiden University Medical Center will work together to expand their research, teaching and development relating to Advanced Therapy Medicinal Products. That is the essence of a Memorandum of Understanding signed at SciLifeLab near Stockholm on Wednesday…